Profile for Classical Chromo Domains
(Peptide) : chromoCC.g Length: 67
Sequences: 23 MaxScore: 121.00
Profile created by: PROFILEWEIGHT version 2.0
Start Residue: 1 End Residue: 78
Gap Penalty Policy: SEARCHWISE
** GO: 4000 (Recommended Gap Opening Penalty)
** GE: 200 (Recommended Gap Extension Penalty)
Sequence Weighting: N-J TREE
Position Weighting: ON
Comparison Matrix: BLOSUM62 Negative (Modified matrix mutabilities)
User Specified Gap Coefficients:-
Local Gap Coefficient: 5
Local Gap Length Coefficient: 5
Remove Gap Positions ( residues in at least 50% of all sequences )
Treat end gaps as partial sequence
Sequence Weights:
1 DmPc 81
2 MoMOD3 78
3 CeYO82 83
4 DmHP1_A 37
5 DvHP1_A 38
6 HuHP1_A 48
7 MoMOD1_A 42
8 MoMOD2_A 51
9 PcHET1_A 57
10 PcHET2_A 65
11 SpSWI6_A 85
12 CeT9A58 90
13 DmSuv3-9 100
14 HuMG44 87
15 CfTENV 67
16 FoSKPY 82
17 MoCHD1_A 78
18 ScYEZ4_A 97
19 MoCHD1_B 95
20 ScYEZ4_B 94
21 MgGRH 88
22 MgMAGGY 89
23 Ce29H12 89
Average Profile Score (total) = -5
Average Profile Score (no gaps) = -6
Cons A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Gap Len ..
E -2 0 -9 1 5 -10 -8 -5 -8 0 1 -7 -3 -1 0 -5 2 -2 2 0 0 -6 -11 -1 -8 4 100 100
D -2 0 -9 1 1 -10 -2 -4 -9 0 -1 -10 -6 -1 0 -1 0 -3 0 -2 0 -6 -10 -1 -8 0 100 100
E -2 0 -15 3 11 -16 -10 -5 -14 0 1 -14 -9 -2 0 -2 3 -3 1 -3 0 -10 -16 -2 -12 8 100 100
G -2 -2 -9 -1 0 -8 -1 -3 -9 0 -4 -9 -6 -1 0 -3 -2 -6 0 -3 0 -7 -10 -2 -7 -1 100 100
E -9 7 -26 13 26 -24 -15 -4 -25 0 7 -24 -15 0 0 -4 9 -3 0 -7 0 -18 -23 -4 -17 21 100 100
E -8 3 -24 7 23 -20 -12 -1 -24 0 3 -22 -13 0 0 -10 12 0 0 -8 0 -18 -19 -4 -12 20 100 100
E -7 -6 -17 -2 8 -8 -15 -7 -6 0 -5 -10 -6 -9 0 -12 -1 -11 -7 -7 0 -2 -14 -3 -5 4 100 100
Y -15 -18 -15 -17 -11 18 -20 6 -10 0 -11 -8 -6 -13 0 -20 -6 -12 -13 -14 0 -11 7 -4 28 -11 100 100
V 2 -11 -10 -8 1 -12 -14 -11 2 0 -6 -4 -2 -11 0 -10 -4 -11 -4 0 0 8 -17 -2 -10 0 100 100
V 4 -32 -8 -29 -21 -11 -27 -27 25 0 -20 9 6 -29 0 -15 -20 -28 -17 -2 0 33 -26 -4 -12 -22 100 100
E -16 16 -52 28 75 -43 -28 0 -48 0 15 -48 -30 0 0 -13 30 0 0 -15 0 -32 -38 -7 -27 64 100 100
K -2 -4 -14 -9 3 -20 -12 -5 -21 0 19 -15 -8 -2 0 -9 4 14 0 -5 0 -16 -18 -3 -13 3 100 100
I -9 -36 -10 -32 -31 -3 -41 -30 42 0 -30 21 10 -31 0 -28 -30 -32 -22 -5 0 35 -27 -5 -11 -33 100 100
L -8 -28 -6 -25 -20 -3 -29 -20 17 0 -16 21 11 -21 0 -21 -15 -16 -15 -8 0 11 -16 -4 -9 -21 100 100
D -4 13 -13 21 8 -22 -8 -9 -22 0 -4 -26 -17 0 0 -5 0 -11 2 -6 0 -19 -24 -3 -19 4 100 100
H -3 -2 -7 -4 0 -8 -8 4 -11 0 2 -10 -6 0 0 -7 0 1 0 -3 0 -9 -10 -2 -2 0 100 100
R -7 -8 -18 -12 1 -17 -16 -4 -18 0 13 -12 -5 -3 0 -13 5 18 -4 -7 0 -16 -18 -3 -11 1 5 5
v -4 -6 -7 -8 -5 -7 -9 -6 -1 0 0 -2 1 -1 0 -8 -3 -3 -2 0 0 0 -9 -2 -6 -4 5 5
k -1 -3 -7 -3 0 -6 -6 -4 -4 0 0 -5 -3 -2 0 -6 -1 0 -1 -1 0 -2 -9 -1 -5 -1 5 5
k -4 0 -8 -3 0 -12 -7 -3 -12 0 6 -8 -4 1 0 -5 3 5 0 -2 0 -10 -11 -2 -8 1 5 5
g -2 -5 -21 -5 -6 -21 25 -8 -30 0 -9 -30 -20 2 0 -14 -8 -10 3 -11 0 -24 -15 -4 -16 -7 100 100
Q -5 -1 -12 -3 0 -12 -4 -4 -12 0 4 -9 -4 1 0 -7 4 0 0 -4 0 -9 -11 -2 -8 1 100 100
V -4 -14 -8 -12 -7 -4 -14 -7 1 0 -6 1 0 -10 0 -6 -5 -7 -7 -4 0 2 -9 -2 -1 -7 100 100
E -7 0 -19 2 15 -13 -14 -2 -15 0 3 -15 -7 -3 0 -9 10 0 -3 -6 0 -9 -14 -3 -7 13 100 100
Y -20 -33 -17 -30 -23 32 -30 7 -4 0 -23 -4 -5 -23 0 -30 -16 -23 -21 -18 0 -6 11 -5 50 -24 100 100
L -11 -32 -11 -29 -22 6 -30 -14 9 0 -16 21 9 -22 0 -24 -13 -15 -17 -11 0 2 -9 -4 4 -23 100 100
V -4 -30 -4 -27 -22 -5 -28 -23 25 0 -19 17 10 -25 0 -20 -19 -24 -18 -4 0 26 -19 -4 -8 -23 100 100
K -14 -1 -36 -14 12 -39 -26 -11 -43 0 64 -29 -13 0 0 -14 13 31 -1 -13 0 -30 -34 -6 -25 13 100 100
W -39 -53 -22 -49 -38 12 -24 -23 -39 0 -38 -26 -12 -49 0 -47 -25 -38 -39 -25 0 -39 121 -15 23 -39 100 100
K -5 -8 -14 -10 0 -15 -15 -7 -12 0 12 -4 -2 -5 0 -10 4 7 -3 -4 0 -9 -15 -3 -10 0 100 100
G -3 -6 -32 -6 -19 -35 58 -18 -50 0 -20 -50 -35 4 0 -22 -20 -18 0 -22 0 -39 -23 -6 -33 -21 100 100
Y -17 -27 -15 -24 -16 19 -24 4 -8 0 -17 -4 -5 -19 0 -25 -10 -18 -18 -15 0 -9 16 -5 36 -18 100 100
S -3 3 -11 5 0 -14 0 -3 -15 0 -4 -17 -11 3 0 0 -2 -7 5 -1 0 -13 -15 -2 -11 -1 5 5
d -5 4 -10 6 6 -7 -6 4 -11 0 -1 -12 -8 1 0 -5 2 -3 0 -4 0 -10 -9 -2 -2 4 5 5
s 0 0 -6 0 1 -8 -5 -4 -7 0 0 -7 -4 1 0 -5 0 -2 5 1 0 -6 -10 -1 -7 0 100 100
E -12 9 -25 13 24 -18 -14 12 -25 0 0 -26 -17 4 0 -10 8 -3 -2 -9 0 -20 -19 -4 -6 20 100 100
N -12 14 -16 3 -3 -25 -5 0 -25 0 -3 -25 -14 30 0 -8 -2 -5 7 -1 0 -23 -29 -5 -18 -3 100 100
T 2 -11 -11 -10 -11 -25 -21 -21 -16 0 -11 -16 -13 1 0 -12 -11 -13 20 58 0 -4 -23 0 -24 -11 100 100
W -36 -48 -21 -45 -35 9 -23 -22 -36 0 -35 -24 -12 -44 0 -43 -23 -35 -35 -19 0 -36 108 -13 20 -36 100 100
E -13 14 -48 26 68 -40 -26 0 -45 0 13 -45 -28 0 0 -13 27 0 3 -12 0 -30 -36 -6 -26 58 100 100
P -8 -11 -23 -3 -6 -33 -15 -15 -28 0 -8 -29 -18 -8 0 40 -7 -17 0 0 0 -20 -31 -8 -25 -7 100 100
E -3 -5 -16 -2 9 -14 -10 -3 -15 0 1 -12 -8 -5 0 -5 2 -1 -3 -6 0 -11 -14 -3 -8 6 100 100
E 0 0 -14 2 12 -15 -9 -5 -13 0 2 -14 -8 -2 0 -7 4 -3 1 -2 0 -8 -16 -2 -11 10 100 100
N -14 13 -18 6 -1 -17 -7 2 -19 0 -4 -18 -12 24 0 -14 -2 -6 4 -1 0 -19 -23 -3 -11 -3 100 100
L -8 -32 -4 -29 -25 -1 -32 -23 24 0 -20 25 15 -24 0 -23 -19 -21 -17 -8 0 17 -17 -4 -8 -26 100 100
D 0 -2 -7 0 0 -9 -5 -6 -5 0 -1 -6 -3 -3 0 -4 -1 -5 0 -1 0 -3 -10 -1 -7 0 5 5
C 2 -6 13 -2 -11 -13 -6 -13 -13 0 -13 -15 -11 -10 0 -13 -12 -15 -1 -6 0 -11 -15 -4 -13 -10 100 100
P 0 -7 -8 -5 -1 -10 -8 -5 -8 0 -1 -7 -2 -5 0 2 1 -3 0 -1 0 -5 -11 -2 -7 0 100 100
E -5 0 -14 1 9 -14 -10 -2 -14 0 6 -12 -6 0 0 -6 7 6 -1 -1 0 -10 -13 -2 -9 8 100 100
L -6 -28 -6 -26 -18 -4 -26 -17 8 0 -11 18 10 -19 0 -20 -10 -11 -13 -8 0 4 -14 -4 -6 -18 100 100
L -7 -30 -9 -26 -21 -2 -31 -22 24 0 -19 22 11 -24 0 -22 -19 -21 -17 -7 0 19 -19 -4 -8 -23 100 100
K -3 3 -12 4 7 -12 -8 -3 -13 0 5 -12 -7 -1 0 -6 3 0 0 -4 0 -10 -13 -2 -8 5 100 100
E -3 2 -13 3 9 -11 -8 0 -13 0 0 -13 -8 2 0 -7 5 -2 0 -4 0 -10 -13 -2 -7 8 100 100
F -18 -30 -16 -27 -24 40 -27 0 -1 0 -24 -3 -3 -23 0 -30 -20 -24 -20 -17 0 -6 9 -5 38 -25 100 100
E -6 -4 -9 -3 3 -4 -11 2 -10 0 0 -8 -4 -3 0 -8 3 -2 -3 -6 0 -8 -5 -2 0 3 100 100
K -3 0 -14 -5 2 -17 -9 -3 -17 0 14 -12 -6 3 0 -7 6 9 2 -2 0 -13 -15 -2 -11 3 100 100
R -5 -2 -12 -4 2 -13 -9 -1 -14 0 8 -10 -5 0 0 -8 3 9 0 -3 0 -12 -11 -2 -8 2 100 100
N -5 -2 -8 -3 0 -4 -7 0 -7 0 -2 -5 -3 0 0 -7 0 -1 -3 -4 0 -7 -4 -2 -1 0 100 100
K -3 0 -11 -2 2 -12 -4 -1 -12 0 4 -11 -5 1 0 -4 4 1 0 -4 0 -9 -11 -2 -7 3 100 100
S 0 -2 -6 -2 0 -7 -3 -3 -6 0 0 -5 -2 -1 0 -5 -1 -2 1 -2 0 -4 -9 -1 -6 0 100 100
K -2 -3 -10 -4 2 -10 -8 -4 -9 0 5 -8 -4 -2 0 -4 0 1 0 0 0 -5 -10 -2 -6 1 100 100
K -4 -1 -9 0 2 -9 -7 -2 -8 0 1 -7 -4 -2 0 -2 0 -1 -1 -3 0 -6 -9 -2 -6 1 100 100
T -2 -3 -9 -3 1 -10 -7 -4 -8 0 2 -6 -3 0 0 -6 0 0 0 1 0 -5 -10 -1 -7 0 100 100
P -4 -4 -10 -4 0 -11 -7 -2 -12 0 0 -10 -5 -2 0 1 2 1 -2 -2 0 -9 -8 -2 -6 0 100 100
R -2 -2 -7 -2 0 -5 -7 -3 -4 0 -1 -4 -1 -2 0 -4 0 -1 -1 -2 0 -3 -8 -1 -5 0 100 100
K -2 -4 -12 -8 -1 -13 -6 -3 -15 0 9 -11 -7 0 0 -6 0 4 -1 -5 0 -11 -13 -2 -8 -1 100 100
X 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5
* 63 0 21 89 238 41 66 29 62 0 152 115 14 67 0 58 59 88 65 57 0 92 55 1 78 0