Profile for Chromo Shadow Domains
(Peptide) : chromoCS.g Length: 67
Sequences: 8 MaxScore: 68.00
Profile created by: PROFILEWEIGHT version 2.0
Start Residue: 1 End Residue: 78
Gap Penalty Policy: SEARCHWISE
** GO: 5000 (Recommended Gap Opening Penalty)
** GE: 200 (Recommended Gap Extension Penalty)
Sequence Weighting: N-J TREE
Position Weighting: ON
Comparison Matrix: BLOSUM62 Negative (Modified matrix mutabilities)
User Specified Gap Coefficients:-
Local Gap Coefficient: 5
Local Gap Length Coefficient: 5
Remove Gap Positions ( residues in at least 50% of all sequences )
Treat end gaps as partial sequence
Sequence Weights:
1 DmHP1_B 50
2 DvHP1_B 44
3 HuHP1_B 37
4 MoMOD1_B 36
5 MoMOD2_B 32
6 PcHET1_B 63
7 PcHET2_B 86
8 SpSWI6_B 100
Average Profile Score (total) = -6
Average Profile Score (no gaps) = -7
Cons A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Gap Len ..
V 0 -12 -5 -10 -8 -7 -7 -10 2 0 -7 0 0 -9 0 -3 -7 -10 -3 -1 0 5 -11 -2 -7 -8 100 100
R -2 0 -9 -3 0 -12 -6 -3 -12 0 6 -10 -5 4 0 -6 1 5 4 3 0 -10 -12 -1 -9 0 100 100
G -4 1 -19 4 -2 -21 20 -9 -28 0 -8 -27 -17 1 0 -10 0 -9 0 -11 0 -21 -15 -3 -17 -2 100 100
F -14 -29 -14 -26 -25 38 -26 -12 7 0 -25 2 2 -26 0 -30 -25 -27 -19 -14 0 2 0 -4 17 -27 100 100
E -3 11 -16 17 18 -17 -7 -4 -18 0 0 -20 -14 0 0 -5 4 -6 1 -5 0 -14 -18 -2 -14 13 100 100
R -12 -1 -24 -12 0 -26 -14 1 -29 0 14 -21 -11 11 0 -17 7 36 -5 -7 0 -29 -25 -4 -17 0 100 100
G -6 -14 -17 -13 -15 -4 17 -2 -22 0 -15 -22 -16 -6 0 -17 -12 -15 -6 -15 0 -17 -2 -4 7 -16 100 100
L -8 -18 -9 -13 -14 -6 -24 -18 9 0 -14 15 6 -16 0 -17 -12 -17 -13 -6 0 6 -17 -3 -10 -16 100 100
E -3 1 -14 4 10 -15 -7 -3 -16 0 4 -15 -9 0 0 2 3 -2 4 -2 0 -12 -15 -2 -11 8 100 100
P 1 -11 -8 -8 -6 -11 -5 -9 -13 0 -6 -12 -7 -9 0 6 -5 -9 0 -3 0 -10 -2 -3 -8 -6 100 100
E -12 12 -39 21 57 -32 -21 0 -36 0 11 -36 -22 0 0 -10 22 0 0 -11 0 -24 -28 -5 -21 48 100 100
k -5 3 -10 1 3 -11 -6 -2 -12 0 9 -10 -6 1 0 -5 2 8 -1 -4 0 -11 -11 -2 -8 2 50 100
I -10 -34 -8 -30 -30 0 -38 -26 37 0 -27 26 12 -28 0 -27 -27 -27 -21 -10 0 27 -23 -4 -9 -31 100 100
L -5 -25 -6 -22 -19 -1 -25 -18 22 0 -16 19 9 -19 0 -17 -16 -18 -14 -5 0 17 -15 -3 -6 -20 100 100
G 2 -7 -20 -6 -14 -24 40 -14 -34 0 -14 -34 -23 2 0 -15 -14 -16 9 -11 0 -27 -17 -3 -23 -14 100 100
A 22 -15 -2 -13 -7 -14 -4 -14 -3 0 -7 -7 -5 -11 0 -8 -7 -11 9 1 0 2 -20 0 -13 -8 100 100
T 0 -9 -6 -8 -9 -10 -14 -13 0 0 -9 -4 -4 -3 0 -9 -9 -10 7 20 0 2 -15 0 -12 -9 100 100
D -17 31 -24 41 16 -26 -10 -8 -29 0 1 -35 -24 7 0 -8 1 -11 0 -9 0 -27 -29 -4 -24 9 100 100
T 0 -2 -6 -4 -4 -10 -6 -6 -4 0 -4 -7 -4 4 0 -7 -4 -6 6 11 0 -1 -13 -1 -9 -4 100 100
S -1 -2 -4 -4 -6 -9 0 -6 -5 0 -6 -8 -5 2 0 -9 -6 -8 4 -1 0 -6 -12 -2 -9 -6 5 5
G 0 -11 -28 -10 -21 -31 62 -19 -46 0 -21 -46 -32 0 0 -20 -21 -21 0 -21 0 -34 -18 -5 -30 -23 100 100
E -2 0 -10 2 7 -12 -7 -3 -12 0 2 -12 -7 1 0 -5 2 2 4 3 0 -10 -12 -1 -9 5 100 100
L -12 -51 -10 -46 -36 0 -46 -32 25 0 -24 51 24 -34 0 -33 -24 -24 -25 -12 0 12 -20 -5 -11 -38 100 100
M -4 -6 -10 -6 2 -9 -13 -7 -6 0 3 -3 5 -4 0 -7 2 -1 -1 1 0 -2 -9 -2 -8 3 100 100
F -17 -29 -14 -26 -27 40 -28 -12 9 0 -27 4 2 -26 0 -32 -27 -27 -19 -16 0 0 0 -4 17 -29 100 100
L -12 -39 -10 -35 -27 5 -35 -17 14 0 -19 31 13 -26 0 -26 -17 -19 -20 -11 0 6 -9 -4 5 -28 100 100
M -7 -25 -6 -22 -18 0 -24 -16 14 0 -12 19 25 -17 0 -16 -8 -12 -11 -7 0 11 -10 -3 -6 -14 100 100
K -5 -1 -16 -5 5 -19 -13 -6 -19 0 20 -13 -5 0 0 -6 10 8 1 2 0 -11 -15 -2 -11 7 100 100
W -22 -30 -13 -28 -23 16 -16 -12 -18 0 -23 -12 -5 -28 0 -29 -17 -23 -22 -15 0 -20 58 -8 16 -24 100 100
K -9 2 -24 0 19 -24 -16 -5 -27 0 31 -21 -11 0 0 -7 11 11 0 -8 0 -18 -21 -4 -15 18 100 100
G -6 6 -17 4 -5 -18 19 -5 -24 0 -8 -25 -17 12 0 -11 -7 -9 2 -8 0 -20 -15 -3 -16 -6 100 100
T 0 -8 -6 -7 -8 -7 -2 -9 0 0 -8 -3 -2 -5 0 -8 -8 -9 0 3 0 2 -10 -1 -8 -8 100 100
D -2 15 -16 24 14 -20 -6 -7 -20 0 -4 -24 -17 0 0 -7 1 -10 1 -5 0 -16 -22 -3 -18 8 100 100
E -6 -3 -14 -1 9 -13 -13 -3 -8 0 1 -8 -4 -3 0 -9 7 2 -4 -5 0 -6 -13 -2 -8 8 5 5
a 31 -15 0 -14 -7 -14 0 -13 -7 0 -7 -7 -7 -14 0 -6 -7 -7 7 0 0 0 -18 0 -13 -7 100 100
D -4 8 -11 13 9 -14 -6 -5 -14 0 -1 -16 -11 3 0 -5 1 -6 7 3 0 -12 -15 -1 -12 6 100 100
L -8 -17 -8 -16 -12 5 -17 0 2 0 -10 8 8 -10 0 -14 -7 -9 -9 -8 0 -1 -5 -2 1 -12 100 100
V -3 -24 -11 -24 -15 -9 -25 -7 18 0 -17 2 3 -20 0 -17 -15 -23 -18 -3 0 27 -22 -4 -3 -16 100 100
P -7 -18 -13 -14 -10 -15 -17 -12 -8 0 -6 -1 -2 -13 0 12 -7 -6 -9 -6 0 -7 -17 -5 -13 -11 100 100
S 20 -7 -4 -6 -3 -15 0 -10 -13 0 -3 -13 -8 -2 0 -7 -3 -8 23 4 0 -10 -20 0 -15 -3 100 100
K -2 -5 -10 -7 -1 -13 -11 -9 -9 0 9 -8 -4 -1 0 -6 -1 0 3 8 0 -3 -14 -1 -10 -1 100 100
E -5 -2 -13 1 7 -10 -14 -8 0 0 -5 -7 -4 -7 0 -9 -1 -9 -5 -4 0 2 -16 -3 -9 4 100 100
A 33 -18 -1 -16 -9 -18 -4 -17 -10 0 -9 -10 -9 -14 0 -9 -9 -9 10 10 0 0 -22 0 -18 -10 100 100
N -18 24 -25 5 0 -27 -2 7 -30 0 2 -28 -17 46 0 -17 1 6 7 -1 0 -30 -31 -4 -17 0 100 100
V -3 -8 -7 -8 -3 -7 -12 -8 2 0 0 0 1 -7 0 -7 -4 -5 -4 0 0 5 -10 -2 -6 -3 100 100
K -8 -6 -22 -13 3 -24 -20 -12 -18 0 35 -14 -5 -5 0 -10 3 9 -4 -7 0 -8 -24 -4 -16 4 5 5
C -2 -25 48 -23 -30 -11 -25 -22 1 0 -24 -2 -4 -23 0 -22 -24 -24 -10 -8 0 0 -15 -8 -13 -25 100 100
P -11 -22 -27 -10 -10 -40 -20 -19 -33 0 -10 -33 -21 -20 0 68 -10 -21 -11 -10 0 -22 -35 -11 -29 -11 100 100
Q -10 -1 -26 -2 17 -28 -19 0 -31 0 11 -21 -1 0 0 -10 45 14 -1 -10 0 -22 -17 -5 -10 28 100 100
L -4 -14 -6 -14 -9 -3 -16 -10 6 0 -2 9 8 -10 0 -10 -5 -5 -7 -4 0 4 -9 -2 -5 -8 100 100
V -3 -26 -7 -24 -17 -5 -25 -20 24 0 -16 12 15 -22 0 -16 -14 -21 -15 -2 0 28 -17 -4 -7 -17 100 100
I -10 -34 -8 -30 -30 0 -38 -26 37 0 -27 26 12 -28 0 -27 -27 -27 -21 -10 0 27 -23 -4 -9 -31 100 100
Q -1 1 -8 3 5 -10 -5 0 -11 0 0 -10 -5 0 0 -4 5 0 1 -3 0 -8 -9 -1 -5 5 100 100
F -19 -29 -16 -26 -25 47 -26 -3 -1 0 -25 -1 -1 -24 0 -32 -24 -25 -19 -18 0 -9 9 -4 31 -27 100 100
Y -22 -33 -18 -30 -21 30 -30 19 -11 0 -21 -11 -10 -20 0 -29 -10 -21 -22 -21 0 -11 17 -5 68 -22 100 100
E -12 12 -39 21 57 -32 -21 0 -36 0 11 -36 -22 0 0 -10 22 0 0 -11 0 -24 -28 -5 -21 48 100 100
E -1 3 -15 4 16 -17 -7 -3 -19 0 7 -18 -10 2 0 -6 7 -1 12 -1 0 -14 -17 -2 -13 14 100 100
R -11 -5 -21 -12 0 -17 -15 19 -25 0 7 -19 -10 2 0 -14 5 26 -8 -10 0 -25 -18 -4 -4 0 100 100
L -12 -51 -10 -46 -36 0 -46 -32 25 0 -24 51 24 -34 0 -33 -24 -24 -25 -12 0 12 -20 -5 -11 -38 100 100
T 0 -4 -8 -4 -1 -15 -11 -9 -12 0 -2 -11 -6 1 0 -6 2 -4 11 22 0 -6 -13 0 -12 0 100 100
W -17 -27 -11 -25 -21 13 -18 -12 -8 0 -19 -1 0 -23 0 -24 -15 -19 -18 -12 0 -11 35 -6 10 -22 100 100
H -8 -4 -10 -7 -4 1 -9 9 -9 0 -3 -8 -5 0 0 -11 -2 0 -5 -6 0 -10 -4 -2 7 -4 100 100
S 0 6 -10 7 7 -13 -3 -2 -14 0 0 -15 -9 6 0 -5 1 -4 10 0 0 -12 -15 -1 -11 5 100 100
N -3 0 -5 1 -2 -8 -5 -2 -10 0 -4 -11 -7 1 0 0 -2 -6 0 -3 0 -8 -9 -2 -3 -2 100 100
P -4 2 -12 1 5 -14 -5 -2 -14 0 4 -13 -7 4 0 2 2 0 3 -2 0 -11 -13 -2 -9 4 100 100
E -3 0 -12 2 13 -9 -9 -2 -9 0 1 -8 0 -1 0 -5 6 -1 0 -3 0 -6 -10 -2 -7 11 100 100
X 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5
* 34 0 8 32 54 26 34 8 32 0 33 46 16 20 0 23 14 27 34 25 0 30 13 0 16 0