SANT profile
This is the profile used with WiseTools programs for profile-based
sequence comparisons of SANT domains.
This version of the profile will only work with the WiseTools.
A profile for GCG programs can be made avaliable upon request.
(Peptide) : sant.aln Length: 50
Sequences: 11 MaxScore: 117.00
Profile created by: PROFILEWEIGHT version 2.0
Date: Fri Nov 3 12:07:22 1995
Start Residue: 5 End Residue: 55
** GCG ** GO: 1.63 (Suggested Gap Opening Penalty for GCG programs)
** GCG ** GE: 0.16 (Suggested Gap Extension Penalty for GCG programs)
** WISE ** GO: 1634 (Suggested Gap Opening Penalty for WISE programs)
** WISE ** GE: 163 (Suggested Gap Extension Penalty for WISE programs)
Sequence Weighting: N-J TREE
Position Weighting: OFF
Comparison Matrix: gon250.bla Negative
Gap: 100 Len: 100
GapRatio: 0.33 LenRatio: 0.10
(Use average gap length for gap extension penalty calculations)
Remove Gap Positions ( residues in at least 50% of all sequences )
Treat end gaps as partial sequence
Sequence Weights:
1 MoNCOR_A 82
2 CeNCOR 94
3 HuKG1Q_A 78
4 HuMTA1 87
5 ScYCR033_A 86
6 CeC04A2_A 100
7 MoNCOR_B 81
8 HuKG1Q_B 90
9 ScYCR033_B 99
10 ScSWI3 94
11 ScYFK7 88
Average Profile Score (total) = -6
Average Profile Score (no gaps) = -4
Cons A C D E F G H I K L M N P Q R S T V W Y Gap Len ..
N -4 -19 9 9 -22 -9 7 -19 7 -21 -15 13 -10 6 6 0 0 -15 -25 -8 100 100
W -31 -9 -49 -40 36 -40 -7 -11 -32 -1 -2 -34 -46 -25 -17 -30 -30 -19 117 37 100 100
T 8 -2 2 0 -24 -3 -2 -11 1 -16 -9 6 2 0 -2 18 20 -4 -34 -19 100 100
D 1 -18 9 8 -28 -10 -2 -14 2 -17 -12 3 1 4 -1 2 2 -7 -39 -21 100 100
E -1 -23 18 21 -30 -7 13 -25 11 -25 -18 10 -5 14 8 2 0 -19 -32 -16 100 100
E 0 -30 32 33 -40 -5 4 -30 10 -31 -22 12 -5 14 2 2 0 -21 -45 -27 100 100
A 1 -11 -7 -1 -13 -13 2 -5 4 -4 1 -3 -8 3 4 0 0 -4 -23 -11 100 100
Q -1 -16 0 5 -19 -13 0 -8 3 -7 -4 1 -7 6 0 1 0 -5 -28 -15 100 100
L -9 -16 -30 -19 7 -36 -14 19 -10 25 18 -21 -19 -10 -12 -15 -8 13 -15 -5 100 100
F -12 -7 -36 -30 44 -40 -5 10 -25 18 14 -25 -28 -19 -25 -19 -15 4 15 28 100 100
L -1 -19 -8 0 -15 -20 -6 -2 2 -1 -1 -7 -2 0 -1 -4 -2 -1 -29 -16 100 100
E 0 -25 17 21 -34 -7 5 -23 16 -24 -16 9 -4 16 11 3 1 -17 -37 -22 100 100
G 6 -13 -4 -5 -33 25 -9 -23 -2 -23 -17 -1 -10 -4 -1 2 -4 -16 -32 -27 100 100
I -12 -12 -34 -25 22 -42 -10 22 -19 23 18 -24 -25 -14 -20 -18 -11 14 -1 10 100 100
K 0 -17 -2 4 -20 -15 -2 -6 7 -8 -4 -2 -8 5 5 0 0 -3 -29 -17 100 100
E -4 -23 5 10 -18 -17 1 -11 6 -11 -5 0 -10 8 2 -3 -2 -9 -27 -13 100 100
H -15 -10 -18 -16 29 -31 29 -6 -11 0 0 -7 -22 -6 -10 -13 -12 -9 14 40 100 100
G 3 -20 0 -4 -43 35 -12 -32 -8 -32 -26 0 0 -6 -9 2 -6 -22 -40 -34 100 100
K 0 -21 6 9 -32 -6 3 -21 22 -22 -15 7 -4 11 21 3 2 -16 -33 -20 100 100
D -2 -22 17 11 -29 -6 4 -20 7 -22 -15 16 -7 9 2 3 2 -15 -36 -18 100 100
F -27 -8 -47 -40 57 -47 -3 0 -33 10 6 -32 -42 -26 -26 -29 -26 -8 75 47 100 100
S 1 -10 2 1 -19 3 10 -21 0 -21 -15 4 -7 3 -1 5 1 -15 -23 -6 100 100
K 0 -18 -2 0 -24 -5 -3 -14 8 -12 -8 0 -9 3 9 -1 -2 -10 -28 -19 100 100
I -7 -10 -37 -26 10 -43 -21 37 -20 28 24 -27 -24 -18 -23 -17 -6 30 -17 -6 100 100
A 10 -3 2 3 -22 -1 4 -13 2 -16 -9 4 0 5 0 11 8 -7 -30 -15 100 100
E -1 -24 16 17 -31 -6 10 -25 14 -24 -17 10 -5 14 12 3 0 -19 -33 -18 100 100
Y -8 -14 -6 -4 3 -23 7 -6 -4 -5 0 -2 -18 -2 -7 -7 -6 -6 -10 10 100 100
L -9 -8 -36 -26 22 -41 -15 26 -21 28 23 -27 -24 -17 -23 -18 -9 20 -5 5 100 100
g 3 -21 -1 -4 -42 28 -12 -31 -8 -30 -25 -1 9 -6 -9 2 -5 -21 -41 -33 50 100
H -6 -16 4 1 -15 -12 12 -18 1 -17 -12 8 -12 2 1 0 0 -15 -13 -4 100 100
K -4 -25 4 10 -29 -11 11 -21 28 -20 -14 7 -6 14 26 0 0 -17 -30 -16 100 100
S 8 -1 3 1 -27 1 -1 -17 3 -20 -13 8 2 2 2 19 14 -9 -31 -18 100 100
V 1 -12 -13 -7 -15 -21 -10 3 -5 0 0 -11 4 -4 -6 -2 1 6 -30 -17 100 100
E 6 -13 6 11 -28 -8 -3 -13 2 -17 -11 1 3 4 -2 6 6 -6 -38 -22 100 100
Q 0 -20 16 15 -28 -7 4 -20 6 -19 -11 8 -4 13 3 4 1 -15 -34 -19 100 100
C -1 45 -34 -27 3 -31 -16 12 -23 10 9 -22 -25 -19 -21 -8 -6 14 -12 -4 100 100
V -3 -10 -22 -13 -5 -30 -13 18 -5 9 9 -15 -17 -7 -6 -9 -1 18 -24 -12 100 100
L -4 -17 -2 0 -13 -16 -2 -5 0 -2 -2 2 -11 0 -4 -2 -1 -5 -26 -12 100 100
Y -17 -10 -25 -21 37 -36 14 -5 -13 1 0 -14 -27 -11 -10 -17 -15 -8 22 45 100 100
Y -22 -5 -32 -30 56 -43 15 -2 -24 5 3 -18 -32 -19 -21 -21 -19 -7 39 70 100 100
Y -16 -8 -27 -22 34 -38 7 3 -17 9 5 -16 -25 -12 -16 -17 -14 0 18 43 100 100
R -3 -13 -7 -4 -12 -16 -1 -4 1 -1 2 0 -11 2 3 -1 0 -4 -20 -11 100 100
W -15 -10 -22 -19 12 -27 0 -7 -15 -2 -3 -9 -24 -11 -11 -11 -9 -9 31 18 100 100
K 0 -24 1 6 -32 -10 1 -20 20 -20 -15 3 9 10 18 2 1 -15 -36 -22 100 100
K -1 -18 -5 0 -22 -15 -1 -7 14 -10 -5 0 -8 5 15 0 1 -5 -28 -17 100 100
T 0 -15 6 8 -28 -8 2 -16 10 -19 -12 7 -3 7 13 7 11 -10 -31 -19 100 100
D -3 -22 12 9 -22 -12 5 -20 1 -21 -16 7 -2 4 -1 0 -2 -15 -31 -13 100 100
N -1 -21 17 10 -34 4 5 -27 9 -29 -21 21 -8 7 7 6 2 -21 -36 -20 100 100
Y -15 -7 -28 -23 30 -35 4 0 -17 4 2 -17 -26 -14 -15 -16 -15 -4 27 39 100 100
K -2 -19 0 2 -21 -17 -3 -6 7 -9 -5 0 -9 2 3 0 3 -3 -32 -17 100 100
* 24 5 28 49 33 22 18 27 61 45 10 25 13 24 27 33 27 28 18 33