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Course INF282

Methods in Bioinformatics I

Course offered :

Current programmes of study

Number of credits 10
Course offered (semester) Spring
Subject overlap I 283: 10 ECTS
Schedule Schedule
Reading list Reading list

Language of Instruction

English

Pre-requirements

At least 120 ECTS in computer science, preferably including some mathematics

Learning Outcomes

After completing the course the student can:

  • describe how log-odds scoring matrices (e.g. PAM, BLOSUM) are developed
  • make programs to align and find patterns in a family of sequences and explain the connection to evolutionary trees
  • describe how protein structures can be described and classified, and make programs to discover similarities (patterns) between two or several structures
  • use knowledge about use of mass spectrometry in proteomics to develop programs relevant in this work
  • understand how DNA-sequencing can be used to characterize genome and gen-expressions, and protein-DNA interactions
  • understand use of micro matrices, sequencing and proteomics in functional genome-research, and make programs for some subtasks

Course offered (semester)

Spring

Language of Instruction

English

Aim and Content

The course mainly consists of methods to analyse biological sequences and structures: description and representation, comparison (in pairs and multiple), description and detection of joint properties (motif), classification.

Learning Outcomes

After completing the course the student can:

  • describe how log-odds scoring matrices (e.g. PAM, BLOSUM) are developed
  • make programs to align and find patterns in a family of sequences and explain the connection to evolutionary trees
  • describe how protein structures can be described and classified, and make programs to discover similarities (patterns) between two or several structures
  • use knowledge about use of mass spectrometry in proteomics to develop programs relevant in this work
  • understand how DNA-sequencing can be used to characterize genome and gen-expressions, and protein-DNA interactions
  • understand use of micro matrices, sequencing and proteomics in functional genome-research, and make programs for some subtasks

Pre-requirements

At least 120 ECTS in computer science, preferably including some mathematics

Recommended previous knowledge

INF 280, STAT 101 (Elementary Statistics)

Subject Overlap

I 283: 10 ECTS

Grading Scale

The grading scale used is A to F. Grade A is the highest passing grade in the grading scale, grade F is a fail.