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Course MOL203

Gene Structure and Function

Course offered :

Current programmes of study

Number of credits 10
Course offered (semester) Autumn
Schedule Schedule
Reading list Reading list

Language of Instruction

English, Norwegian if only norwegianspeaking students participate.

Pre-requirements

Basic knowledge in molecular biology.

Learning Outcomes

After completing the course, the students should be able to:

  • make use of knowledge about structure of nucleic acids to understand transfer and maintenance of genetic information
  • explain chromatin organization of DNA with emphasis to function in regulation of genes
  • combine knowledge about mechanisms in transcription, splicing and translation to explain regulation of genes
  • identify the significance of DNA damage and repair
  • able to compare molecular mechanisms in gene regulation in pro-and eukaryotic organisms

Contact Information

Study advisor at the Departement of Molecular Biology, advice@mbi.uib.no .

Course Coordinator

Professor Rune Male, rune.male@mbi.uib.no

Course offered (semester)

Autumn

Language of Instruction

English, Norwegian if only norwegianspeaking students participate.

Aim and Content

The course reviews the molecular basis of structure and physiology of prokaryote and eukaryote cells. The course deals with; structure of DNA, RNA and chromatin; maintenance of the genome through replication, repair and recombination; expression of the genome through gene regulation, transcription, RNA splicing and translation. Gene technology methods used in studies of biological mechanisms and structures will be presented. The course is obligatory in the bachelor degree in molecular biology.

Learning Outcomes

After completing the course, the students should be able to:

  • make use of knowledge about structure of nucleic acids to understand transfer and maintenance of genetic information
  • explain chromatin organization of DNA with emphasis to function in regulation of genes
  • combine knowledge about mechanisms in transcription, splicing and translation to explain regulation of genes
  • identify the significance of DNA damage and repair
  • able to compare molecular mechanisms in gene regulation in pro-and eukaryotic organisms

Pre-requirements

Basic knowledge in molecular biology.

Recommended previous knowledge

Basic knowledge of molecular biology (equivalent to MOL202), molecular cell biology (equivalent to MOL201).

 

Assessment methods

Written exam 4 hours.

No aids allowed.

Grading Scale

The grading scale used is A to F. Grade A is the highest passing grade in the grading scale, grade F is a fail.

Contact Information

Study advisor at the Departement of Molecular Biology, advice@mbi.uib.no .