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Centre for Cancer Biomarkers CCBIO

CCBIO international affiliated investigators

Klaus Pantel

Professor Pantel did his MD at the University of Cologne in 1986, Dr.Med. at the University of Cologne in 1987 and Dr.med.habil. at the Ludwig-Maximillians-Universitaet in 1995. He is currently director of the Institute of Tumor Biology at the University Medical Center Hamburg-Eppendorf.

The pioneer work of Professor Pantel in the field of cancer micrometastasis, circulating tumor cells and circulating nucleic acids (ctDNA, microRNAs) is reflected by more than 400 publications in high ranking biomedical and scientific journals and has been awarded the AACR Outstanding Investigator Award 2010, the German Cancer Award 2010, and the ERC Advanced Investigator Grant 2011. Moreover, Professor Pantel coordinates the European TRANSCAN group “CTC-SCAN”, the European IMI consortium CANCER-ID (www.cancer-id.eu) on blood-based “Liquid Biopsies” and serves on the editorial boards of international cancer journals (e.g., Clin. Cancer Res., Breast Cancer Res., Cancer Res.).

Professor Pantel has established a clinical micrometastasis research network at the University Cancer Center Hamburg with a clear focus on diagnosis and treatment of solid tumors. Moreover, their laboratory for CTC analyses serves as central diagnostic center in various large-scale national and international clinical trials.

Professor Pantel’s expertise is particularly on disseminating tumor cells as biomarker of treatment efficacy. This work provides new insights into the biology of early tumor cell dissemination in cancer patients with particular emphasis on the identification of the putative metastatic founder cells (“stem cells”) and the regulation of cancer dormancy responsible for late relapses in breast cancer patients.