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PhD course

Cancer Genomics

Course description

Language of instruction

English

Course content

This course will provide broad understanding of aspects of cancer genome biology and their investigation by next generation sequencing (NGS) technologies. Methods for analysing DNA variation and structure and RNA expression patterns will be covered, as well as nuclear and chromatin structure. Also ethical, legal aspects, and hereditary predisposition will be taught.

Learning outcomes

Upon completing this course the candidate should have:

Knowledge regarding

  • What kinds of mutations may predispose for, contribute to, or appear during cancer development
  • How these variants can be detected by NGS methods and be analysed bioinformatically
  • How to employ these methods to stratify patients both diagnostically and therapeutically
  • The different implications of the same aberrations depending on tissue type
  • Ethical and legal regulations regarding genetic analyses of patient samples

Skills

  • Can formulate problems, plan and carry out NGS analyses on samples from cancer patients.
  • Be able to assess the expediency and application of different NGS methods in cancer diagnostics and research
  • To know the contact points for NGS analysis and data storage and analysis in the Bergen area
  • Be able to communicate relevant literature and methods concerning cancer genomics

General Competency

  • Be able to evaluate how knowledge about genome aberrations can help in understanding tumor biological mechanisms and as a guide to improved diagnosis, targeted treatment and follow up of cancer patients.

Study period

Once per year (fall)

Credits (ECTS)

3 ECTS

Specific terms

Course registration and deadlines

Register via StudentWeb (http://studentweb.uib.no) before 1st of September

Pre-requirements

 Master¿s degree or equivalent education level is required, with the exception of students on the Medical Student Research Programme.

Recommended previous knowledge

Medical or health related educational background or PhD project related to medical / health related research. Basic knowledge of cancer and cell biology is required.

Part of training component

Recommended as part of the training component for all candidates affiliated with the Research School for Cancer Studies (RSCS)

Form of assessment

To pass the course, the candidate must:

  • Participate during at least 90% of the course
  • Participate actively in the group
  • 10-15 min long oral presentation to the other participants about a method related to own project
  • Pass a one hour written exam. The exam will be evaluated by the course-coordinator

Grading scale:

pass / fail

Course overlap

No

Who may participate

The course is primarily intended for PhD candidates who are affiliated with the Centre for Cancer Biomarkers (CCBIO), but is also open to other students, PhD candidates and students at the Medical Student Research Program.

Addtional information

Programme

3 full days with lectures and seminars

Group discussions with individual presentations

Program: http://vedlegg.uib.no/?id=c9b476e3bddb59d812c0127b4e1c9e09

Reading curriculum (see mandatory reading)

Contact

Academic responsibility:

Ola Myklebost

Administration:

Solveig Lund Witsø@uib.no

Academic responsibility

Students who have been admitted to a program of study at the University of Bergen that includes access to this course are eligible to register. For information about admission requirements see Admission.

Lecturers

TBA

Course location

Bergen

Exam information

  • Note that the time may change up until 14 days prior to the day of the examination. The location will be published 14 days ahead.

  • Type of assessment: Written test

Study period

Once per year (fall)