Rein Aasland's picture
Rein
Aasland
Head of Department
, Professor
Visit Address: 
HIB - Thormøhlensgt. 55
5020 Bergen
Postal Address: 
Postboks 7803
5020 Bergen
Phone: 
+47 55 58 45 31
+47 924 25 456
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Journal articles
  • Rack, Johannes Gregor M; Lutter, Timo; Bjerga, Gro Elin Kjæreng; Guder, Corina; Ehrhardt, Christine; Varv, Signe; Ziegler, Mathias; Aasland, Rein. 2014. The PHD finger of p300 influences its ability to acetylate histone and non-histone targets. Journal of Molecular Biology. doi: 10.1016/j.jmb.2014.08.011
  • Rack, Johannes Gregor M; Van Linden, Magali R; Lutter, Timo; Aasland, Rein; Ziegler, Mathias. 2014. Constitutive nuclear localization of an alternatively spliced sirtuin-2 isoform. Journal of Molecular Biology. 426: 1677-1691. doi: 10.1016/j.jmb.2013.10.027
  • Taxt, Arne Michael; Diaz, Yuleima; Bacle, Amélie; Grauffel, Cédric; Reuter, Nathalie; Aasland, Rein; Sommerfelt, Halvor; Puntervoll, Pål. 2014. Characterization of immunological cross-reactivity between enterotoxigenic Escherichia coli heat-stable toxin and human guanylin and uroguanylin. Infection and Immunity. 82: 2913-2922. doi: 10.1128/IAI.01749-14
  • Hoppmann, Verena; Thorstensen, Tage; Kristiansen, Per Eugen; Veiseth, Silje Veie; Rahman, Mohummad Aminur; Finne, Kenneth; Aalen, Reidunn B.; Aasland, Rein. 2011. The CW domain, a new histone recognition module in chromatin proteins. EMBO Journal. 30: 1939-1952. doi: 10.1038/emboj.2011.108
  • Xiao, Bing; Sanders, Matthew J.; Underwood, Elizabeth; Heath, Richard; Mayer, Faith V.; Carmena, David; Jing, Chun; Walker, Philip; Eccleston, John F.; Haire, Lesley F.; Saiu, Peter; Howell, Steven A.; Aasland, Rein; Martin, Stephen R.; Carling, David; Gamblin, Steven J. 2011. Structure of mammalian AMPK and its regulation by ADP. Nature. 472: 230-233. doi: 10.1038/nature09932
  • Denoeud, France; Henriet, Simon; Mungpakdee, Sutada; Aury, Jean-Marc; Da Silva, Corinne; Brinkmann, Henner; Mikhaleva, Iana; Olsen, Lisbeth Charlotte; Jubin, Claire; Canestro, Cristian; Bouquet, Jean-Marie; Danks, Gemma Barbara; Poulain, Julie; Campsteijn, Coen; Adamski, Marcin; Cross, Ismael; Yadetie, Fekadu; Muffato, Matthieu; Louis, Alexandra; Butcher, Stephen; Tsagkogeorga, Georgia; Konrad, Anke; Singh, Sarabdeep; Jensen, Marit Flo; Cong, Evelyne Huynh; Otterå, Helen Eikeseth; Noel, Benjamin; Anthouard, Veronique; Porcel, Betina M; Kachouri-Lafond, Rym; Nishino, Atsuo; Ugolini, Matteo; Chourrout, Pascal; Nishida, Hiroki; Aasland, Rein; Huzurbazar, Snehalata; Westhof, Eric; Delsuc, Frédéric; Lehrach, Hans; Reinhardt, Richard; Weissenbach, Jean; Roy, Scott W; Artiguenave, Francois; Postlethwait, John H; Manak, J Robert; Thompson, Eric; Jaillon, Olivier; Du Pasquier, Louis; Boudinot, Pierre; Liberles, David A; Volff, Jean-Nicolas; Philippe, Hervé; Lenhard, Boris; Crollius, Hugues Roest; Wincker, Patric; Chourrout, Daniel. 2010. Plasticity of Animal Genome Architecture Unmasked by Rapid Evolution of a Pelagic Tunicate. Science. 330: 1381-1385. doi: 10.1126/science.1194167
  • Gould, Cathryn M.; Diella, Francesca; Via, Allegra; Puntervoll, Pål; Gemünd, Christine; Chabanis-Davidson, Sophie; Michael, Sushama; Sayadi, Ahmed; Bryne, Jan Christian; Chica, Claudia; Seiler, Markus; Davey, Norman E.; Haslam, Neill; Weatheritt, Robert J.; Budd, Aidan; Hughes, Timothy; Pas, Jakub; Rychlewski, Leszek; Trave, Gilles Michel; Aasland, Rein; Helmer-Citterich, Manuela; Linding, Rune; Gibson, Toby J. 2010. ELM: the status of the 2010 eukaryotic linear motif resource. Nucleic Acids Research. 38: D167-D180. doi: 10.1093/nar/gkp1016
  • Justin, Neil; De Marco, Valeria; Aasland, Rein; Gamblin, Steven J. 2010. Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies. Current opinion in structural biology. 20: 730-738. doi: 10.1016/j.sbi.2010.09.012
  • Taxt, Arne Michael; Aasland, Rein; Sommerfelt, Halvor; Nataro, James; Puntervoll, Pål. 2010. Heat-stable enterotoxin of enterotoxigenic escherichia coli as a vaccine target. Infection and Immunity. 78: 1824-1831. doi: 10.1128/IAI.01397-09
  • Buchanan, Luke; Durand-Dubief, Mickaël; Roguev, Assen; Cagri, Sakalar; Wilhelm, Brian; Stålfors, Annelie; Shevchenko, Anna; Aasland, Rein; Shevchenko, Andrej; Ekwall, Karl; Stewart, Francis. 2009. The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. PLoS Genetics. 5. 13 pages. doi: 10.1371/journal.pgen.1000726
  • Thorstensen, Tage; Grini, Paul E.; Mercy, Inderjit S.; Alm, Vibeke; Erdal, Sigrid; Aasland, Rein; Aalen, Reidunn B. 2008. The Arabidopsis SET-domain protein ASHR3 is involved in stamen development and interacts with the bHLH transcription factor ABORTED MICROSPORES (AMS). Plant Molecular Biology. 66: 47-59. doi: 10.1007/s11103-007-9251-y
  • Pánek, Josef; Eidhammer, Ingvar; Aasland, Rein. 2007. Using hydropathy features for function prediction of membrane proteins. Molecular membrane biology. 24: 304-312. doi: 10.1080/09687860701213884
  • Glaser, Stefan; Schaft, Julia; Lubitz, Sandra; Vintersten, Kristina; van der Hoeven, Frank; Tufteland, Katharina Reksten; Aasland, Rein; Anastassiadis, Konstantinos; Ang, Siew-Lan; Stewart, A. Francis. 2006. Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development. Development. 133: 1423-1432. doi: 10.1242/dev.02302
  • Panek, Josef; Eidhammer, Ingvar; Aasland, Rein. 2005. A New Method for Identification of Protein (Sub)Families in a Set of Proteins Based on Hydropathy Distribution in Proteins. Proteins: Structure, Function, and Genetics. 58: 923-934.
  • Slagsvold, Thomas; Aasland, Rein; Hirano, Satoshi; Bache, Kristi g; Raiborg, Camilla; Trambaiolo, Daniel; Wakatsuki, Soichi; Stenmark, Harald. 2005. Eap45 in Mammalian ESCRT-II Binds Ubiquitin via a Phosphoinositide-interacting GLUE Domain. Journal of Biological Chemistry. 280: 19600-19606.
  • Aasland, Rein. 2004. Calico-katter og X-kromosominaktivering, et vakkert eksempel på epigenetisk genregulering. Naturen. 128: 262-263.
  • Aasland, Rein. 2004. Temahefte om epigenetikk (leder). Naturen. 128: 202-203.
  • Aasland, Rein; Puntervoll, Pål. 2004. Prediksjon av funksjonelle seter i proteiner med ELM. NBS-nytt. 28: 33.
  • Bjerga, Gro Elin Kjæreng; Aasland, Rein. 2004. Livets hemmelighet. Bergens Tidende. Published 2004-09-27.
  • Brehm, Alexander; Tufteland, Katharina Reksten; Aasland, Rein; Becker, Peter B. 2004. The many colours of chromodomains. Bioessays. 26: 133-140.
  • Dichtl, Berhard; Aasland, Rein; Keller, Walther. 2004. Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA: A publication of the RNA Society. 10: 965-977.
  • Eidhammer, Ingvar; Aasland, Rein; Coward, Eivind; Jonassen, Inge. 2004. Utdanningsmuligheter innen bioinformatikk ved UIB. NBS-nytt. 28: 8.
  • Korenjak, Michael; Taylor-harding, Barbie; Binne, Ulrich; Satterlee, John s.; Stevaux, Olivier; Aasland, Rein; White-cooper, Helen; Dyson, Nick; Brehm, Alexander. 2004. Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell. 119: 181-193.
  • Puntervoll, Pål; Aasland, Rein. 2004. Hvordan bruke BLAST til å undersøke sekvenser? NBS-nytt. 28: 19-20.
  • Ragvin, Anja; Aasland, Rein. 2004. Histonkoden: en mekanisme for cellulær hukommelse. Naturen. 128: 220-227.
  • Ragvin, Anja; Valvatne, Håvard; Erdal, Sigrid; Årskog, Vibeke; Tufteland, Katharina Reksten; Breen, Kamilla; Øyan, Anne Margrete; Eberharter, Anton; Gibson, Toby; Becker, Peter B.; Aasland, R; Aasland, Rein. 2004. Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300. Journal of Molecular Biology. 337: 773-788. doi: 10.1016/j.jmb.2004.01.051
  • Puntervoll, Pål; Linding, Rune; Gemünd, Christine; Chabanis-Davidson, Sophie; Mattingsdal, Morten; Cameron, Scott; Martin, David M. A.; Auselio, Gabriele; Brannetti, Barbara; Costantini, Anna; Ferrè, Fabrizio; Maselli, Vincenza; Via, Allegra; Cesareni, Gianni; Diella, Francesca; Superti-Furga, Giulio; Wyrwicz, Lucjan; Ramu, Chenna; McGuigan, Caroline; Gudavalli, Rambabu; Letunic, Ivica; Bork, Peer; Aasland, Rein. 2003. ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins. Nucleic Acids Research. 31: 3625-3630.
  • Roguev, Assen; Schaft, Daniel; Shevchenko, Anna; Aasland, Rein; Shevchenko, Andrej; Stewart, Francis. 2003. High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. Journal of Biological Chemistry. 278: 8487-8493.
  • Aasland, Rein; Ampe, C.; Ball, L. J.; Bedford, M. T.; Cesareni, G.; Gimona, M.; Hurley, J. H.; Jarchau, T.; Lehto, V. P.; Lemmon, M. A.; Linding, Rune; Mayer, B. J.; Nagai, M.; Sudol, M.; Walter, U.; Winder, S. J. 2002. Normalization of nomenclature for peptide motifs as ligands of modular protein domains. FEBS Letters. 513: 141-144.
  • Conklin, Darrell; Jonasen, Inge; Aasland, Rein; Taylor, William R. 2002. Association of nucleotide patterns with gene function classes: application to human 3' untranslated sequences. Bioinformatics. 18: 182-189.
  • Stenmark, Harald Alfred; Aasland, Rein; Driscoll, P. 2002. The phosphatidylinositol 3-phosphate-binding FYVE finger. FEBS Letters. 513: 77-84.
  • Stenmark, Harald; Aasland, Rein. 2002. The phosphatidylinositol 3-phosphate-binding FYVE finger. FEBS Letters. 513: 77-84.
  • Aasland, Rein. 2001. Paper Alerts on Nucleus and Gene Expression. Current Opinion in Cell Biology. 13. 5 pages.
  • Aasland, Rein. 2001. Paper Alerts on Chromatin and Expression Mechanisms. Current Opinion in Genetics and Development. 10. 5 pages.
  • Pijnappel, W.W.; Schaft, Daniel; Roguev, Assen; Shevchenko, Anna; Tekotte, Hille; Wilm, Matthias; Rigaut, Guillaume; Seraphin, Bertrand; Aasland, Rein; Stewart, A. Francis. 2001. The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes & Development. 15: 2991-3004.
  • Roguev, Assen; Schaft, Daniel; Shevchenko, Anna; Pijnappel, W.W.; Wilm, Matthias; Aasland, Rein; Stewart, A. Francis. 2001. The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO Journal. 20: 7137-7148.
  • Stenmark, Harald Alfred; Aasland, Rein. 1999. FYVE-finger proteins - effectors of an inositol lipid. Journal of Cell Science. 112: 4175-4183.
  • Stenmark, Harald; Aasland, Rein. 1999. FYVE finger proteins - effectors of an inositol lipid. Journal of Cell Science. 112: 4175-4183.
  • Gasser, Susan M.; Paro, Renato; Stewart, A. Francis; Aasland, Rein. 1998. The genetics of epigenetics. Cellular and Molecular Life Sciences (CMLS). 54: 1-5.
  • Gaullier, Jean-Michel; Simonsen, Anne; Bremnes, Bjørn; Aasland, Rein; Stenmark, Harald Alfred. 1998. FYVE fingers bind PtdIns(3)P. Nature. 394: 432-433.
  • Gaullier, Jean-Michel; Simonsen, Anne; DArrigo, Antonello; Bremnes, Bjørn; Aasland, Rein; Stenmark, Harald. 1998. FYVE fingers bind PtdIns(3)P. Nature. 394: 432-433. Published 1998-07-30.
  • Gibson, Toby J.; Ramu, Chenna; Gemund, Christine; Aasland, Rein. 1998. The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor. TIBS -Trends in Biochemical Sciences. Regular ed.. 23: 242-244.
  • Olsen, Lisbeth Charlotte; Aasland, Rein; Fjose, Anders. 1997. A vasa-like gene i zebrafish identifies putative primordial germ cells. Mechanisms of Development. 66: 95-106.
  • Lorens, J.B.; Aasland, Rein; Brunstad, H.; Bergh, H.; Male, Rune. 1996. Two variants of the pituitary specific transcription factor Pit-1 in Atlantic salmon. Journal of Molecular Endocrinology. 17: 225-236.
  • Stenmark, Harald Alfred; Aasland, Rein; Toh, Ban-Hock. 1996. Endosomal localization of the autoantigen EEA1 is mediated by a zink-binding FYVE finger. Journal of Biological Chemistry. 271: 24048-24054.
  • Lorens, James; Nerland, Audun H.; Aasland, Rein; Lossius, Ivar; Male, Rune. 1993. Expression of growth hormone genes in Atlantic salmon. Journal of Molecular Endocrinology. 11: 167-179.
  • Ness, G. O.; Aasland, Rein; Lillehaug, Johan. 1993. Growth requirements and oncogene expression in the humen thyroid cell line SGHTL-34. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 101: 767-776.
  • Slupphaug, G.; Markussen, F.-H.; Olsen, Lisbeth Charlotte; Aasland, Rein; Aarsæther, Niels; Bakke, O.; Krokan, H. E.; Helland, Dag Emil. 1993. Human Uracil-DNA glycosylase is shared by the nucleus and the mitochondria. Nucleic Acid Res. 21: 2579-2584.
  • Olsen, Lisbeth Charlotte; Aasland, Rein; Krokan, H. E.; Helland, Dag Emil. 1992. Human uracil DNA glycosylase cDNA complements E.coli ung mutants. Nucleic Acid Res. 19: 4473-4478.
  • Molven, Anders; Aasland, Rein. 1991. Fakta om transkripsjonsfaktorer. NBS-nytt. 4: 9-13.
  • Slupphaug, G.; Olsen, Lisbeth Charlotte; Helland, Dag Emil; Aasland, Rein; Krokan, H. E. 1991. Cell cycle regulation and in vitro hybrid arrest analysis of the major human uracil- DNA glycosylase. Nucleic Acids Research. 19: 5131-5137.
  • Sommerfelt, Halvor; Grewal, Harleen; Gaastra, W.; Bhan, M. K.; Svennerholm, A-M.; Kalland, Karl-Henning; Asphaug, V.; Aasland, Rein; Bjorvatn, B. 1991. Presence of cfaD-homologous sequences and expression of coli surface antigen 4 on enterotoxigenic Escherichia coli; relevance for diagnostic procedures. Microbial Pathogenesis. 11: 297-304.
  • Aasland, Rein; Lillehaug, Johan; Varhaug, Jan Erik; Kleppe, K. 1990. Coexpression of the genes encoding transforming growth factor-_a and its receptor in papillary carcinomas of the thyoid. International Journal of Cancer. 46: 382-387.
  • Aasland, Rein; Olsen, Lisbeth Charlotte; Spurr, N. K.; Krokan, H. E.; Helland, Dag Emil. 1990. Chromosomal assignment of Human Uracil-DNA Glycosylase to Chromosome 12. Genomics. 7.
  • Albretsen, Catrine; Haukanes, Bjørn Ivar; Aasland, Rein; kleppe, kjell. 1988. Optimal Conditions for Hybridization With Oligonucleotides: A Study With myc-Oncogenic DNA Probes. Analytical Biochemistry. 170: 193-202.
Reports and theses
  • Lycke, Kirsten Hofgaard; Eriksen, Harald M.; Hanken, Ingrid Maria; Granaas, Rakel Christina; Aasland, Rein; Løfgren, Trond. 2009. Utredning om etablering av Sentre for fremragende utdanning (SFU). Innstilling fra Universitets- og høgskolerådet til Kunnskapsdepartemtentet. 15. juni 2009. Universitets- og høgskolerådete, Oslo. 57 pages.
  • Aasland, Rein. 1991. Oncogenes and growth factors in thyroid carcinogenesis.
Book sections
  • Puntervoll, Pål; Aasland, Rein. 2004. Nomenclatures for protein modules and their cognate motifs. 22, pages 477-487. In:
    • Sudol, Marius. 2004. Modular Protein Domains. Wiley-VCH Verlagsgesellschaft. 524 pages. ISBN: 3-527-30813-X.
  • Aasland, Rein; Stewart, A Francis. 1999. Analysis of DNase I hypersensitive sites in chromatin by cleavage in permeabilised cells. 355-362. In:
    • Becker, PB. 1999. Chromatin Protocols,in the series: Methods in Molecular Biology.
  • Lossius, Ivar; Kryvi, Harald; Lorens, James; Male, Rune; Nerland, Audun H.; Olsen, L.; Telle, Wenche; Totland, Geir Kåre; Aasland, Rein. 1993. Cloning and characterization of growth regulating genes from Atlantic salmon: A strategy for increasing growth rate by microinjection of a modified growth hormone gene into fertilized salmon eggs. 40-46. In:
    • [Mangler etternavn], [Mangler fornavn]. 1993. Physiol and Biochem of Marine Fish Larvae. (Red.: Walther, B. T., Fyhn, H. J.).

More information in national current research information system (CRIStin)

Selected publications:

Rack JGM, Lutter T, Bjerga GEK, Guder C, Ehrhardt C, Varv S, Ziegler M, and Aasland R. 2014. The PHD finger of p300 influences its ability to acetylate histone and non-histone targets. Journal of Molecular Biology (in press) .doi: 10.1016/j.jmb.2014.08.011

Rack JGM, Van Linden MR, Lutter T, Aasland R, and Ziegler M. 2014. Constitutive nuclear localization of an alternatively spliced sirtuin-2 isoform. Journal of Molecular Biology. 426:1677-1691. 

Hoppmann V, Thorstensen T, Kristiansen PE, Veiseth SV, Rahman MA, Finne K, Aalen RB, and Aasland R.  (2011) The CW domain, a new histone recognition module in chromatin proteins. EMBO J. 30: 1939-1952..

Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ. (2011) Structure of mammalian AMPK and its regulation by ADP. Nature 472:230-233. 

Denoeud F, Henriet S, Mungpakdee S, Aury JM, Da Silva C, Brinkmann H, Mikhaleva J, Olsen LC, Jubin C, Cañestro C, Bouquet JM, Danks G, Poulain J, Campsteijn C, Adamski M, Cross I, Yadetie F, Muffato M, Louis A, Butcher S, Tsagkogeorga G, Konrad A, Singh S, Jensen MF, Cong EH, Eikeseth-Otteraa H, Noel B, Anthouard V, Porcel BM, Kachouri-Lafond R, Nishino A, Ugolini M, Chourrout P, Nishida H, Aasland R, Huzurbazar S, Westhof E, Delsuc F, Lehrach H, Reinhardt R, Weissenbach J, Roy SW, Artiguenave F, Postlethwait JH, Manak JR, Thompson EM, Jaillon O, Du Pasquier L, Boudinot P, Liberles DA, Volff JN, Philippe H, Lenhard B, Roest Crollius H, Wincker P, and Chourrout D. (2010) Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate. Science. 330:1381-5.

Justin N, De Marco V, Aasland R, and Gamblin SJ. (2010) Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies. Curr Opin Struct Biol. 20:730-8.

Taxt A, Aasland R, Sommerfelt H, Nataro J, and Puntervoll P. (2010) Heat-stable enterotoxin of enterotoxigenic Escherichia coli as a vaccine target. Infect Immun. 78:1824-31.

Gould CM, Diella F, Via A, Puntervoll P, Gemünd C, Chabanis-Davidson S, Michael S, Sayadi A, Bryne JC, Chica C, Seiler M, Davey NE, Haslam N, Weatheritt RJ, Budd A, Hughes T, Pas J, Rychlewski L, Travé G, Aasland R, Helmer-Citterich M, Linding R, and Gibson TJ. ELM: the status of the 2010 eukaryotic linear motif resource. Nucleic Acids Res. 2010 Jan;38(Database issue):D167-80. 

Buchanan L, Durand-Dubief M, Roguev A, Sakalar C, Wilhelm B, Strålfors A, Shevchenko A, Aasland R, Shevchenko A, Ekwall K, and Francis Stewart A. (2009) The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. PLoS Genet. 5:e1000726

Thorstensen T, Grini PE, Mercy IS, Alm V, Erdal S, Aasland R, and Aalen RB. (2008) The Arabidopsis SET-domain protein ASHR3 is involved in stamen development and interacts with the bHLH transcription factor ABORTED MICROSPORES (AMS). Plant Mol Biol. 66:47-59

Glaser S, Schaft J, Lubitz S, Vintersten K, van der Hoeven F, Tufteland KR, Aasland R., Anastassiadis, K, Ang, SL., and Stewart, AF. (2006) Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development. Development.133:1423-1432.

Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, and Stenmark H. (2005) Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain. J Biol Chem. 2005 280:19600-6.

Ragvin A, Valvatne H, Erdal S, Årskog V, Tufteland KR, Breen K, Øyan AM, Eberharter A, Gibson TJ, Becker PB, and  Aasland R. (2004) Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300. J Mol Biol. 337:773-88.

Korenjak M, Taylor-Harding B, Binne UK, Satterlee JS, Stevaux O, Aasland R, White-Cooper H, Dyson N, and Brehm A. (2004) Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell. 119:181-93

Puntervoll P, Linding R, Gemund C, Chabanis-Davidson S, Mattingsdal M, Cameron S, Martin DM, Ausiello G, Brannetti B, Costantini A, Ferre F, Maselli V, Via A, Cesareni G, Diella F, Superti-Furga G, Wyrwicz L, Ramu C, McGuigan C, Gudavalli R, Letunic I, Bork P, Rychlewski L, Kuster B, Helmer-Citterich M, Hunter WN, Aasland R, and Gibson TJ. (2003) ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins. Nucleic Acids Res. 31:3625-3630.

Roguev A, Schaft D, Shevchenko A, Aasland R, Shevchenko A, and Stewart AF. (2003) High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. J Biol Chem. 278:8487-8493.

Conklin D, Jonassen I, Aasland R, and Taylor WR. (2002) Association of nucleotide patterns with gene function classes: application to human 3' untranslated sequences. Bioinformatics. 18:182-189.

Pijnappel, W.W., Schaft D., Roguev, A., Schevchenko, A., Tekotte, H., Wilm, M., Rigaut, G., Seraphin B., Aasland, R., and Stewart, A.F. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev. 15, 2991-3004

Roguev, A., Schaft, D., Schevchenko, A., Pijnappel, W.W., Wilm, M., Aasland, R., and Stewart, A.F. (2001) The Saccharomyces cerevisiae Set1 complex includes and Ash2 homologue and methylates histone 3 lysine 4. EMBO J. 20, 137-148

Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Aasland R., Stenmark H (1998) FYVE fingers bind PtdIns(3)P. Nature 394:432-3. 

Gibson, T.J., Ramu, C. Christine Gemund, C., and Aasland, R. (1998). The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor. Trends Biochem. Sci. 23(7):242-244

Aasland, R., Stewart, A. F., and Gibson, T. J. (1996). The SANT domain:A putative DNA binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem. Sci. 21, 87-88.

Aasland, R., and Stewart, A. F. (1995). The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1. Nucl. Acids. Res. 23, 3168-3173.

Aasland, R., Gibson, T. J., and Stewart, A. F. (1995). The PHD-finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem. Sci. 20, 56-59.

 

 

 

 

Brief CV:

  • Cand. scient. (UiB, 1983) - Thesis: "Proteins Associated with the Chromatin of E. coli."
  • Dr. scient. (UiB, 1991) - Thesis: "Oncogenes and Growth Factors in Thyroid Carcinogenesis"
  • Post-doc (EMBL, Heidelberg, 1992-1995) - Chromatin-based gene regulation
  • Assoc.prof (Fellslaboratorium for bioteknologi, UiB, 1995-1996)
  • Assoc.prof (Department of Molecular Biology, UiB, 1997-2001
  • Professor (Department of Molecular Biology, UiB, 2002-)
  • Senior scientist (Computational Biology Unit, BCCS, 2002-)
  • Visiting scientist, NIMR/MRC (May 2010 - Jan 2011)

Competence:

  • Molecular biology: gene regulation, proteins, protein domains
  • Applied bioinformatics: sequence and structure analysis of proteins