Eivind Valen
Professor, Associate group leader at Sars Centre and NCMM
- E-mailEivind.Valen@uib.no
- Phone+47 55 58 40 74
- Visitor AddressHIB / Thormøhlensgt. 55Room5133
- Postal AddressPostboks 78035020 Bergen
Announcements:
Press (mostly Norwegian):
- Nye metoder for lesing av DNA gir bedre utsikter
- Discovery of Apela/Toddler
- Rekruttering til Bergen
- Kartleggingen av menneskets promotere
Interviews (mostly Norwegian):
- Forskerforum - Her er forskernes beste tips for å holde seg faglig oppdatert
- Forskning.no - Så langt har forskere kommet med å bruke gensaksen CRISPR på mennesker
- Forskning.no - Dataprogram avdekker fusk i cellene dine
- Forskningsetikk og Teknisk Ukeblad - Frykt og håp rundt ny genteknologi
Panel debates (mostly Norwegian):
- Bergen Film Festival - Alt du vil vite om CRISPR (men ikke våger å spørre om)
- Arendalsuka - KUNSTIG INTELLIGENS I HELSESEKTOREN: NØKKELEN TIL ET LENGRE LIV, MEN…?
Video:
- Study bioinformatics at UiB (Norwegian)
I teach BINF201: Introduction to Omics
Academic article
- (2023). Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes. Diabetologia. 2226-2237.
- (2022). Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore cDNA sequencing. Nature Methods.
- (2022). Long-read single-molecule RNA structure sequencing using nanopore. Nucleic Acids Research (NAR). 11 pages.
- (2021). Rapid genome editing by CRISPR-Cas9-POLD3 fusion. eLIFE. 28 pages.
- (2021). ORFik: a comprehensive R toolkit for the analysis of translation. BMC Bioinformatics. 1-16.
- (2021). Deep conservation of ribosome stall sites across RNA processing genes. NAR Genomics and Bioinformatics. 1-13.
- (2021). CRISPR Genome Editing Made Easy Through the CHOPCHOP Website. Current Protocols in Bioinformatics.
- (2020). Profiling of Small Ribosomal Subunits Reveals Modes and Regulation of Translation Initiation. Cell reports. 18 pages.
- (2020). Intellectual disability in KATP channel neonatal diabetes. Diabetes Care. 526-533.
- (2020). Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation. PLoS Genetics. 1-25.
- (2020). Assessment of tumor suppressor promoter methylation in healthy individuals. Clinical Epigenetics. 1-15.
- (2019). tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing. RNA: A publication of the RNA Society. 1229-1241.
- (2019). Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR. BMC Genomics.
- (2019). CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing. Nucleic Acids Research (NAR). W171-W174.
- (2019). Accurate analysis of genuine CRISPR editing events with ampliCan. Genome Research. 843-847.
- (2018). Shoelaces: An interactive tool for ribosome profiling processing and visualization. BMC Genomics. 6 pages.
- (2017). Ribosome signatures aid bacterial translation initiation site identification. BMC Biology. 1-14.
- (2017). REPARATION: ribosome profiling assisted (re-) annotation of bacterial genomes. Nucleic Acids Research (NAR).
- (2016). Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature Communications.
- (2016). CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering. Nucleic Acids Research (NAR).
- (2015). Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell reports. 875-883.
- (2014). Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nature Communications.
Lecture
- (2022). Rapid genome editing by CRISPR-Cas9-POLD3 fusion. .
Editorial
- (2022). Nye CRISPR-metoder og mer presis presisjonsmedisin. Tidsskrift for Den norske legeforening.
Doctoral dissertation
- (2019). Understanding translational landscapes through the footprints of ribosomes.
Poster
- (2022). CRISPR-Cas9 T cell editing pipeline for Finnish founder diseases.
Academic literature review
- (2022). Small Open Reading Frames, How to Find Them and Determine Their Function. Frontiers in Genetics.
- (2021). Transcript Isoform-Specific Estimation of Poly(A) Tail Length by Nanopore Sequencing of Native RNA. Methods in molecular biology. 543-567.
More information in national current research information system (CRIStin)
CRISPR genome engineering
RNA Biology
Nanopore sequencing
Regulation of Translation
Homepage: ValenLab
Publications: Scholar
Press
- Searching for micropeptides (Norwegian)
- The CRISPR revolution (Norwegian)
- The discovery of Apela/Toddler
- Bergen Research Foundation Rectruitment Grant (Norwegian)
- Moving to Bergen (Norwegian)
- The human promoter atlas