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  • E-mailhalvor.sommerfelt@uib.no
  • Phone+47 55 58 85 75+47 406 40 882
  • Visitor Address
    Overlege Danielssens hus, 5 floor, Årstadveien 21
    5020 Bergen
    Room 
    515
  • Postal Address
    Postboks 7804
    5020 Bergen

Halvor Sommerfelt is a professor in epidemiology and global health at the Centre for International Health, and the Director of the Centre for Intervention Science in Maternal and Child Health (www.uib.no/en/cismac) and senior consultant at the Norwegian Institute of Public Health in Oslo. He has through international collaborative ventures with research groups in India, Nepal, Guinea-Bissau, Uganda, Zambia and South Africa, Europe, and the U.S. and with external funding from the Research Council of Norway, EU, NORAD, WHO, The Norwegian Programme for Development, Research and Education (NUFU) coordinated front-line research accompanied by capacity strengthening aimed at treating and preventing important childhood infections and promoting child growth, development and survival. His research spans basic molecular microbiological studies aimed at vaccine development, experimental immunological studies, molecular epidemiological studies, vaccine trials, and intervention trials of downstream biomedical and behavioral interventions to prevent pneumonia, diarrhea and severe bacterial infection (sepsis) to identify ways of preventing and treating these and other important childhood infections and reducing their nutritional insult.

Sommerfelt has co-authored almost 130 scientific papers reporting on original scientific work published in international peer-reviewed journals, (co-)authored 29 reviews, protocol papers, opinion papers, and letters to editors, held several lectures at research institutions in Europe, India, sub-Saharan Africa and the US, and has acted as a referee for several scientific journals. He has organized international scientific meetings on vaccine research and on maternal and child health. He holds 2 active patents, one for a vaccine candidate for childhood diarrhea, another for an ingestible untethered capsule to collect intestinal fluids.  

He was from 2001 to 2003 the Norwegian representative in the Working group and Steering committee of the planning project for the European and Developing Countries Clinical Trials Partnership (www.edctp.org), was in 2007 appointed to the GAVI Alliance’s Independent Assessment Committee for Advance Market Commitment for vaccines (http://www.vaccineamc.org), and a member of the epidemiology steering committee of The Global Enterics Multi-Center Study (http://medschool.umaryland.edu/GEMS). He has been an expert to several WHO advisory groups, including on non-specific effects of vaccines (https://www.who.int/immunization/research/implementation/nse_protocol_comments/en) and volunteer challenge models for developing COVID-19 vaccines (www.tinyurl.com/WHOHumanChallengeCOVID19). Sommerfelt is a member of the Data Safety Monitoring Board for WHO’s Solidarity trial(s) for COVID-19 vaccines (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/global-research-on-novel-coronavirus-2019-ncov/accelerating-a-safe-and-effective-covid-19-vaccine).

He has supervised 14 PhD candidates, all have defended their theses.

 

H-index 42 (web of science); 45 (Scopus)

    Sommerfelt teaches medical students, master students and PhD candidates in international health and epidemiology.

    He established three courses in epidemioogy at the Centre for International Health, Dept of of Global Public Health and Primary Care, including what is now INTH321A "Experimental epidemiology", in which he also teaches.

    His main areas of interst/competenece are: 

    • Epidemiology with a focus on Randomized controlled trials
    • Global Health
    • Child Health
    Academic article
    • Show author(s) (2023). Strong Association between Diarrhea and Concentration of Enterotoxigenic Escherichia coli Strain TW10722 in Stools of Experimentally Infected Volunteers. Pathogens. 13 pages.
    • Show author(s) (2022). Umbilical cord stump infections in central Uganda: Incidence, bacteriological profile, and risk factors. International Journal of Environmental Research and Public Health (IJERPH). 12 pages.
    • Show author(s) (2022). Effect of kangaroo mother care initiated in community settings on financial risk protection of low-income households: a randomised controlled trial in Haryana, India. BMJ Global Health. 1-9.
    • Show author(s) (2022). Effect of community-initiated kangaroo mother care on breastfeeding performance in low birthweight infants: A randomized clinical trial. Maternal & Child Nutrition. 9 pages.
    • Show author(s) (2022). Early child stimulation, linear growth and neurodevelopment in low birth weight infants. BMC Pediatrics. 9 pages.
    • Show author(s) (2022). A comparison of risk factors for cryptosporidiosis and non-cryptosporidiosis diarrhoea: A case-case-control study in Ethiopian children. PLoS Neglected Tropical Diseases. 20 pages.
    • Show author(s) (2021). Vaginal colonization with antimicrobial-resistant bacteria among women in labor in central Uganda: prevalence and associated factors. Antimicrobial Resistance and Infection Control. 11 pages.
    • Show author(s) (2021). Pathogens Associated With Linear Growth Faltering in Children With Diarrhea and Impact of Antibiotic Treatment: The Global Enteric Multicenter Study. Journal of Infectious Diseases. S848-S855.
    • Show author(s) (2021). Health equity impact of community-initiated kangaroo mother care: a randomized controlled trial. International Journal for Equity in Health. 8 pages.
    • Show author(s) (2021). Global research priorities on COVID-19 for maternal, newborn, child and adolescent health. Journal of Global Health. 12 pages.
    • Show author(s) (2021). Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial. JAMA Network Open. 1-12.
    • Show author(s) (2021). Effect of Community-Initiated Kangaroo Mother Care on Fecal Biomarkers of Gut Function in Low Birth Weight Infants in North India: A Randomized Clinical Trial. American Journal of Tropical Medicine and Hygiene. 945-952.
    • Show author(s) (2020). Vaginal colonisation of women in labour with potentially pathogenic bacteria: A cross sectional study at three primary health care facilities in Central Uganda. BMC Infectious Diseases. 1-10.
    • Show author(s) (2020). Neonatal sepsis at Mulago national referral hospital in Uganda: Etiology, antimicrobial resistance, associated factors and case fatality risk. PLOS ONE.
    • Show author(s) (2020). Community initiated kangaroo mother care and early child development in low birth weight infants in India-a randomized controlled trial. BMC Pediatrics. 1-12.
    • Show author(s) (2020). Antenatal uterotonics as a risk factor for intrapartum stillbirth and first-day death in Haryana, India: A nested case-control study. Epidemiology. 668-676.
    • Show author(s) (2019). The incidence, aetiology, and adverse clinical consequences of less severe diarrhoeal episodes among infants and children residing in low-income and middle-income countries: a 12-month case-control study as a follow-on to the Global Enteric Multicenter Study (GEMS). The Lancet Global Health. e568-e584.
    • Show author(s) (2019). Prolonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopia. Tropical medicine & international health. 1088-1097.
    • Show author(s) (2019). Immunizations with enterotoxigenic Escherichia coli heat-stable toxin conjugates engender toxin-neutralizing antibodies in mice that also cross-react with guanylin and uroguanylin. Infection and Immunity. 1-12.
    • Show author(s) (2019). Experimental infection of human volunteers with the heat-stable enterotoxin-producing enterotoxigenic Escherichia coli strain TW11681. Pathogens. 1-14.
    • Show author(s) (2019). Effects of complementary feeding on attained height among lower primary school-aged children in Eastern Uganda: A nested prospective cohort study. PLOS ONE. 1-17.
    • Show author(s) (2019). Effect of community-initiated kangaroo mother care on survival of infants with low birthweight: a randomised controlled trial. The Lancet. 1724-1736.
    • Show author(s) (2019). Diarrhoeal disease and subsequent risk of death in infants and children residing in low-income and middle-income countries: analysis of the GEMS case-control study and 12-month GEMS-1A follow-on study. The Lancet Global Health. e204-e214.
    • Show author(s) (2019). Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS). PLoS Neglected Tropical Diseases. 1-27.
    • Show author(s) (2019). A New Human Challenge Model for Testing Heat-Stable Toxin-Based Vaccine Candidates for Enterotoxigenic Escherichia Coli Diarrhea - Dose Optimization, Clinical Outcomes, and CD4+ T Cell Responses. PLoS Neglected Tropical Diseases. 19 pages.
    • Show author(s) (2018). Proliferation of enterotoxigenic Escherichia coli strain TW11681 in stools of experimentally infected human volunteers. Gut Pathogens. 8 pages.
    • Show author(s) (2018). Kangaroo mother care: Using formative research to design an acceptable community intervention. BMC Public Health.
    • Show author(s) (2018). "We shall count it as a part of kyogero": acceptability and considerations for scale up of single dose chlorhexidine for umbilical cord care in Central Uganda. BMC Pregnancy and Childbirth.
    • Show author(s) (2017). Zinc as an adjunct treatment for reducing case fatality due to clinical severe infection in young infants: study protocol for a randomized controlled trial. BMC Pharmacology & Toxicology. 1-10.
    • Show author(s) (2017). When is a randomised controlled trial health equity relevant? Development and validation of a conceptual framework. BMJ Open. 9 pages.
    • Show author(s) (2017). Predictors of death in infants with probable serious bacterial infection. Pediatric Research. 784-790.
    • Show author(s) (2017). Impact of community-initiated Kangaroo Mother Care on survival of low birth weight infants: Study protocol for a randomized controlled trial. Trials. 1-10.
    • Show author(s) (2017). Efficacy of umbilical cord cleansing with a single application of 4% chlorhexidine for the prevention of newborn infections in Uganda: Study protocol for a randomized controlled trial. Trials. 1-9.
    • Show author(s) (2017). Early versus late BCG vaccination in HIV-1-exposed infants in Uganda: Study protocol for a randomized controlled trial. Trials. 1-17.
    • Show author(s) (2017). CONSORT-Equity 2017 extension and elaboration for better reporting of health equity in randomised trials. BMJ Global Health. 14 pages.
    • Show author(s) (2016). Towards rational design of a toxoid vaccine against the heatstable toxin of Escherichia coli. Infection and Immunity. 1239-1249.
    • Show author(s) (2016). The Burden of Cryptosporidium Diarrheal Disease among Children < 24 Months of Age in Moderate/High Mortality Regions of Sub-Saharan Africa and South Asia, Utilizing Data from the Global Enteric Multicenter Study (GEMS). PLoS Neglected Tropical Diseases.
    • Show author(s) (2016). Salivary IgA from the sublingual compartment as a novel noninvasive proxy for intestinal immune induction. Mucosal Immunology. 884-893.
    • Show author(s) (2016). Nutritional intake and status of cobalamin and folate among non-pregnant women of reproductive age in Bhaktapur, Nepal. Nutrients.
    • Show author(s) (2016). Extended pre-exposure prophylaxis with lopinavir-ritonavir versus lamivudine to prevent HIV-1 transmission through breastfeeding up to 50 weeks in infants in Africa (ANRS 12174): a randomised controlled trial. The Lancet. 566-573.
    • Show author(s) (2016). Effects of an exclusive breastfeeding intervention for six months on growth patterns of 4-5 year old children in Uganda: The cluster-randomised PROMISE EBF trial. BMC Public Health. 9 pages.
    • Show author(s) (2015). Prevalence of iron deficiency and anemia among young children with acute diarrhea in Bhaktapur, Nepal. Healthcare. 593-606.
    • Show author(s) (2015). Predictors of time to recovery in infants with probable serious bacterial infection. PLOS ONE. 11 pages.
    • Show author(s) (2015). Predictors of duration and treatment failure of severe pneumonia in hospitalized young nepalese children. PLOS ONE. 11 pages.
    • Show author(s) (2015). Microbiota that affect risk for shigellosis in children in low-income countries. Emerging Infectious Diseases. 242-250.
    • Show author(s) (2015). Cost-effectiveness of peer counselling for the promotion of exclusive breastfeeding in Uganda. PLOS ONE. 18 pages.
    • Show author(s) (2015). Child survival and BCG vaccination: A community based prospective cohort study in Uganda. BMC Public Health. 10 pages.
    • Show author(s) (2014). Growth effects of exclusive breastfeeding promotion by peer counsellors in sub-Saharan Africa: the cluster-randomised PROMISE EBF trial. BMC Public Health. 12 pages.
    • Show author(s) (2014). Experimental infection of healthy volunteers with enterotoxigenic Escherichia coli wild-type strain TW10598 in a hospital ward. BMC Infectious Diseases. 9 pages.
    • Show author(s) (2014). Effect of withholding breastfeeding on the immune response to a live oral rotavirus vaccine in North Indian infants. Vaccine. A134-A139.
    • Show author(s) (2014). Effect of implementation of Integrated Management of Neonatal and Childhood Illness programme on treatment seeking practices for morbidities in infants: cluster randomised trial. BMJ. British Medical Journal.
    • Show author(s) (2014). Early infant feeding practices in three African countries: the PROMISE-EBF trial promoting exclusive breastfeeding by peer counsellors. International Breastfeeding Journal. 19.
    • Show author(s) (2014). Cobalamin and folate status in 6 to 35 months old children presenting with acute diarrhea in Bhaktapur, Nepal. PLOS ONE.
    • Show author(s) (2014). Characterization of immunological cross-reactivity between enterotoxigenic Escherichia coli heat-stable toxin and human guanylin and uroguanylin. Infection and Immunity. 2913-2922.
    • Show author(s) (2013). Quantitative PCR for Detection of Shigella Improves Ascertainment of Shigella Burden in Children with Moderate-to-Severe Diarrhea in Low-Income Countries. Journal of Clinical Microbiology. 1740-1746.
    • Show author(s) (2013). Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age. American Journal of Clinical Nutrition. 310-317.
    • Show author(s) (2013). Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. The Lancet. 209-222.
    • Show author(s) (2012). Zinc as adjunct treatment in infants aged between 7 and 120 days with probable serious bacterial infection: a randomised, double-blind, placebo-controlled trial. The Lancet. 2072-2078.
    • Show author(s) (2012). The high burden of infant deaths in rural Burkina Faso: a prospective community-based cohort study. BMC Public Health. 15 pages.
    • Show author(s) (2012). The global enteric multicenter study (GEMS) of diarrheal disease in infants and young children in developing countries: epidemiologic and clinical methods of the case/control study. Clinical Infectious Diseases. S232-S245.
    • Show author(s) (2012). Statistical methods in the Global Enteric Multicenter Study (GEMS). Clinical Infectious Diseases. S246-S253.
    • Show author(s) (2012). Risk factors for extended duration of acute diarrhea in young children. PLOS ONE.
    • Show author(s) (2012). Lopinavir/Ritonavir versus Lamivudine peri-exposure prophylaxis to prevent HIV-1 transmission by breastfeeding: the PROMISE-PEP trial Protocol ANRS 12174. BMC Infectious Diseases. 11 pages.
    • Show author(s) (2012). Effect of implementation of Integrated Management of Neonatal and Childhood Illness (IMNCI) programme on neonatal and infant mortality: cluster randomised controlled trial. BMJ. British Medical Journal. 13 pages.
    • Show author(s) (2012). Case/Control studies with follow-up: constructing the source population to estimate effects of risk factors on development, disease, and survival. Clinical Infectious Diseases. s262-s270.
    • Show author(s) (2012). A randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young children. Pediatrics. 701-708.
    • Show author(s) (2011). Vaccination coverage and timeliness in three South African areas: a prospective study. BMC Public Health. 11 pages.
    • Show author(s) (2011). RNA viruses in young Nepalese children hospitalized with severe pneumonia. The Pediatric Infectious Disease Journal. 1032-1036.
    • Show author(s) (2011). Poor folate status predicts persistent diarrhea in 6- to 30-month-old north Indian children. Journal of Nutrition. 2226-2232.
    • Show author(s) (2011). Perinatal mortality in Eastern Uganda: A community based prospective cohort study. PLOS ONE. 7 pages.
    • Show author(s) (2011). ORS containing zinc does not reduce duration or stool volume of acute diarrhea in hospitalized children. Journal of Pediatric Gastroenterology and Nutrition - JPGN. 161-167.
    • Show author(s) (2011). Malaria Parasitaemia among Infants and Its Association with Breastfeeding Peer Counselling and Vitamin A Supplementation: A Secondary Analysis of a Cluster Randomized Trial. PLOS ONE. 8 pages.
    • Show author(s) (2011). Is vaccination coverage a good indicator of age-appropriate vaccination? A prospective study from Uganda. Vaccine. 3564-3570.
    • Show author(s) (2011). Exclusive breastfeeding promotion by peer counsellors in sub-Saharan Africa (PROMISE-EBF): a cluster-randomised trial. The Lancet. 420-427.
    • Show author(s) (2011). Distribution of Classical and Nonclassical Virulence Genes in Enterotoxigenic Escherichia coli Isolates from Chilean Children and tRNA Gene Screening for Putative Insertion Sites for Genomic Islands. Journal of Clinical Microbiology. 3198-3203.
    • Show author(s) (2011). Cobalamin Status Modifies the Effect of Zinc Supplementation on the Incidence of Prolonged Diarrhea in 6-to 30-Month-Old North Indian Children. Journal of Nutrition. 1108-1113.
    • Show author(s) (2011). A Comparative genomic analysis of diverse clonal types of enterotoxigenic escherichia coli reveals pathovar-specific conservation. Infection and Immunity. 950-960.
    • Show author(s) (2010). Zinc supplementation for four months does not affect growth in young north Indian children. Journal of Nutrition. 630-634.
    • Show author(s) (2010). Two weeks of zinc administration to Nepalese children with pneumonia does not reduce the incidence of pneumonia or diarrhea during the next six months. Journal of Nutrition. 1677-1682.
    • Show author(s) (2010). Respiratory viruses in Nepalese children with and without pneumonia: a case-control study. The Pediatric Infectious Disease Journal. 731-735.
    • Show author(s) (2010). Prospective hospital-based surveillance to estimate rotavirus disease burden in the Gauteng and North West Province of South Africa during 2003-2005. Journal of Infectious Diseases. S131-S138.
    • Show author(s) (2010). Perinatal mortality in rural Burkina Faso: a prospective community-based cohort study. BMC Pregnancy and Childbirth. 9 pages.
    • Show author(s) (2010). Maternal education is associated with vaccination status of infants less than 6 months in Eastern Uganda: a cohort study. BMC Pediatrics.
    • Show author(s) (2010). Clinical presentation and severity of viral community-acquired pneumonia in young Nepalese children. The Pediatric Infectious Disease Journal. e1-e6.
    • Show author(s) (2010). Ancestral Lineages of Human Enterotoxigenic Escherichia coli. Journal of Clinical Microbiology. 2916-2924.
    • Show author(s) (2010). A randomized controlled trial of the effect of zinc as adjuvant therapy in children 2-35 mo of age with severe or nonsevere pneumonia in Bhaktapur, Nepal. American Journal of Clinical Nutrition. 1667-1674.
    • Show author(s) (2009). Zinc deficiency is common among healthy women of reproductive age in Bhaktapur, Nepal. Journal of Nutrition. 594-597.
    • Show author(s) (2009). RNA viruses in community-acquired childhood pneumonia in semi-urban Nepal; a cross-sectional study. BMC Medicine. 12 pages.
    • Show author(s) (2008). Multi-country analysis of the effects of diarrhoea on childhood stunting. International Journal of Epidemiology. 816-830.
    • Show author(s) (2007). Prevalence of iron deficiency and anemia among healthy women of reproductive age in Bhaktapur, Nepal. European Journal of Clinical Nutrition. 262-269.
    • Show author(s) (2007). Folate, but not vitamin B-12 status, predicts respiratory morbidity in north Indian children. American Journal of Clinical Nutrition. 139-144.
    • Show author(s) (2007). Community cohort study of Cryptosporidium parvum infections: sex-differential incidences associated with BCG and diptheria-tetanus-pertussis vaccinations. Vaccine. 2733-2741.
    • Show author(s) (2007). Cobalamin and folate status in infants and young children in a low-to-middle income community in India. American Journal of Clinical Nutrition. 1302-1309.
    • Show author(s) (2005). Intervention studies for improving global health and health care: an important arena for epidemiologists. Norsk Epidemiologi. 123-126.
    • Show author(s) (2004). Protection from natural infections with enterotoxigenic Escherichia coli: longitudinal study. Ugeskrift for Læger. 4051-4053.
    • Show author(s) (2004). Predictors of plasma zinc concentrations in children with acute diarrhea. American Journal of Clinical Nutrition. 451-456.
    • Show author(s) (2004). Identification and molecular characterization of the gene encoding coli surface antigen 20 of enterotoxigenic Escherichia coli. FEMS Microbiology Letters. 131-138.
    • Show author(s) (2004). Cost-effectiveness of zinc as adjunct therapy for acute childhood diarrhoea in developing countries. Bulletin of the World Health Organization. 523-531.
    • Show author(s) (2004). Clonal relatedness of enterotoxigenic Escherichia coli strains isolated from a cohort of young children in Guinea-Bissau. Journal of Clinical Microbiology. 3100-3107.
    • Show author(s) (2003). Vitamin A supplementation and childhood mortality: amplification of the non-specific effects of vaccines? International Journal of Epidemiology. 822-828.
    • Show author(s) (2003). The immune response to pneumococcal polysaccharide vaccine in zinc depleted mice. Scandinavian Journal of Immunology. 76-80.
    • Show author(s) (2003). Protection from natural infections with enterotoxigenic Escherichia coli: longitudinal study. The Lancet. 286-291.
    • Show author(s) (2003). Protection from natural infections with enterotoxigenic Escherichia coli: longitudinal study. The Lancet. 286-291.
    • Show author(s) (2003). Intestinal and systemic immune responses to an oral B-subunit-whole-cell cholera vaccine administered during zinc supplementation. Infection and Immunity. 3909-3913.
    • Show author(s) (2003). Effects of zinc deficiency and pneumococcal surface protein A immunization on zinc status and the risk of severe infection in mice. Infection and Immunity. 2009-2013.
    • Show author(s) (2003). Effects of zinc deficiency and pneumococcal surface protein A immunization on zinc status and the risk of severe infection in mice. Infection and Immunity. 2009-2013.
    • Show author(s) (2003). Development and evaluation of genotypic assays for the detection and characterization of enterotoxigenic Escherichia coli. Diagnostic microbiology and infectious disease. 97-105.
    • Show author(s) (2003). Cohort study of Guinean children: incidence, pathogenicity, conferred protection and attributable risk for enteropathogens during the first 2 years of life. Journal of Clinical Microbiology. 4238-4245.
    • Show author(s) (2003). Cohort study of Guinean children: incidence, pathogenicity, conferred protection and attributable risk for enteropathogens during the first 2 years of life. Journal of Clinical Microbiology. 4245 pages.
    • Show author(s) (2003). Characterization of nontypeable rotavirus strains from Guinea-Bissau: Identification of G8 and G9 types and a high frequency of mixed infections. Virology. 125-133.
    • Show author(s) (2002). Substantial Reduction in Severe Diarrheal Morbidity by Daily Zinc Supplementation in Young North Indian Children. Pediatrics. 86.
    • Show author(s) (2002). Protective immunity after natural rotavirus infection. A community cohort study of newborn children in Guinea-Bisau, West Africa. Journal of Infectious Diseases. 593-597.
    • Show author(s) (2002). Enterotoxigenic Escherichia coli infections and diarrhea in a cohort of young children in Guinea-Bissau. Journal of Infectious Diseases. 1740-1747.
    • Show author(s) (2002). Efficacy of Zinc-fortified oral rehydration solution in 6- to 35-month-old children with acute diarrhea. Journal of Pediatrics. 677-682.
    • Show author(s) (2002). Effectiveness and efficacy of zinc for the treatment of acute diarrhea in young children. Pediatrics. 898-903.
    • Show author(s) (2002). Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. BMJ. British Medical Journal. 1358-1362.
    • Show author(s) (2002). Clonal clustering and colonization factors among thermolabile and porcine thermostable enterotoxin-producing Escherichia coli. APMIS - Journal of Pathologiy, Microbiology and Immunology. 665-672.
    • Show author(s) (2002). Antigenic variation within the subunit protein of members of the colonization factor antigen I group of fimbrial proteins in human enterotoxigenic Escherichia coli. International Journal of Medical Microbiology. 43-50.
    • Show author(s) (2001). Pneumococcal pulmonary infection, septicemia and survival in young zinc-depleted mice. British Journal of Nutrition. 301-306.
    • Show author(s) (2001). Micronutrient deficiency in children. Commentary. British Journal of Nutrition. 199-203.
    • Show author(s) (2001). Genotypic simultaneous detection of enterotoxigenic Escherichia coli harbouring genes for colonisation factor antigen I, coli surface antigens 1, 2, 4, 17, or putative colonisation factor O166. APMIS - Journal of Pathologiy, Microbiology and Immunology. 447-453.
    • Show author(s) (2001). Community-based controlled trial of dietary management of children with persistent diarrhea: sustained beneficial effect on ponderal and linear growth. American Journal of Clinical Nutrition. 968-974.
    • Show author(s) (2000). The measurement of specific IgA in fecal extracts and in intestinal lavage fluid for the monitoring of mucosal immune responses. Journal of Immunological Methods (JIM). 53-62.
    • Show author(s) (2000). Measurement of specific IgA in faecal extracts and intestinal lavage fluid for monitoring of mucosal immune responses. Journal of Immunological Methods (JIM). 53-62.
    • Show author(s) (2000). Genotype Profiles of Rotavirus Strains from Children in a Suburban Community in Guinea-Bissau, Western Africa. Journal of Clinical Microbiology. 264-267.
    • Show author(s) (1999). Community-based randomized controlled trial of reduced osmolarity oral rehydration solution in acute childhood diarrhea. Pediatr Infect Dis J. 789-795.
    • Show author(s) (1997). Expression of colonization factor antigen I fimbriae by enterotoxigenic Escherichia coli; influence by growth conditions and a recombinant positive regulatory gene. APMIS - Journal of Pathologiy, Microbiology and Immunology. 247-254.
    • Show author(s) (1997). Expression of colonization factor antigen I by enterotoxigenic <I>Escherichia coli</I>; influence of growth conditions and a recombinant positive regulatory gene. APMIS - Journal of Pathologiy, Microbiology and Immunology. 247-254.
    • Show author(s) (1997). A new putative colonization factor, CS19, of human enterotoxigenic Escherichia coli. Infection and Immunity. 507-513.
    • Show author(s) (1997). A new fimbrial putative colonization factor, CS19 in human enterotoxigenic <I>Escherichia coli</I>. Infection and Immunity. 507-13.
    • Show author(s) (1996). Identification and characterization of a new putative colonization fac tor of enterotoxigenic Escherichia coli. Infection and Immunity. 2635-2642.
    • Show author(s) (1996). Colonization factors of enterotoxigenic Esherichia coli isolated from children in North India. Journal of Infectious Diseases. 768-776.
    • Show author(s) (1996). Colonization factors of enterotoxigenic Echerichia coli isolated from children in North India. Journal of Infectious Diseases. 768-776.
    • Show author(s) (1994). Genotypic and phenotypic identification of coli surface antigen 6-positive enterotoxigenic Escherichia coli. Journal of Clinical Microbiology. 1295-1301.
    • Show author(s) (1993). Induction of Colonization Factor Antigen I and Coli Surface Antigen 4 of enterotoxigenic Escherichia coli. Vaccine. 221-226.
    • Show author(s) (1993). Evaluation of DNA-DNA hybridization for the direct detection of enterotoxigenic Escherichia coli in stool blots. Scandinavian Journal of Infectious Diseases. 457-463.
    • Show author(s) (1993). Enteroaggregative Escherichia coli, a possible new pathogen causing acute and persistent diarrhea. Scandinavian Journal of Infectious Diseases. 579-583.
    • Show author(s) (1992). Use of nonradioactive DNA Hybridization for the identification of enterotoxigenic Escherichia coli harboring genes for colonization factor antigen/1, coli surface antigen 4 and putative colonization factor 0166. Journal of Clinical Microbiology. 1823-1828.
    • Show author(s) (1992). Genetic relationship of putative colonization factor 0166 to colonization factor antigen I and coli surface antigen 4 of enterotoxigenic Escherichia coli. Infection and Immunity. 3799-3806.
    • Show author(s) (1992). Colonization factor antigen I, coli surface antigen 4 and putative colonization factor 0166 of enterotoxigenic Escherichia coli are genetically related. Vaccine. 289-289.
    • Show author(s) (1991). Presence of cfaD-homologous sequences and expression of coli surface antigen 4 on enterotoxigenic Escherichia coli; relevance for diagnostic procedures. Microbial Pathogenesis. 297-304.
    • Show author(s) (1991). Nucleic acid hybridization for the identification of enterotoxigenic Escherichia coli. Reviews in Medical Microbiology. 138-146.
    • Show author(s) (1989). Mechanism of spontaneous loss of heat-stable toxin (STa) Production in enterotoxigenic Escherichia coli. APMIS - Journal of Pathologiy, Microbiology and Immunology. 436-440.
    • Show author(s) (1988). Comparative Study of Colony Hybridization With Synthetic Oligonucleotide Probes and Enzyme-Linked Immunosorbent Assay for Identification of Enterotoxigenic Escherichia Coli. Journal of Clinical Microbiology. 530-534.

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    CISMAC - Centre for intervention science in maternal and child health

    ETECVac (https://www.uib.no/en/rg/etecvac). The project aims to develop vaccines against the important diarrheagenic bacterium enterotoxigenic Escherichia coli (ETEC), and has developed a patented toxoid which is now being evaluated for inclusion in an enteric vaccine development program by Valneva (https://valneva.com). The project has also established the to date only Scandinavian Controlled Human Infection Model (CHIM). In this model, we infect volunteers with ETEC so that approximately three quarters of them develop diarrhea. The model is an effective means to, in so called phase IIb trials, experimentally evaluate the efficacy of ETEC vaccine candidates, such as those developed by ETECVac.  For further details, please see: