Home
  • E-mailJelena.Mrdalj@uib.no
  • Phone+47 55 58 60 83
  • Visitor Address
    Jonas Liesvei 91
    5009 Bergen
    Room 
    9th floor, Bygg for biologiske basalfag (BBB)
  • Postal Address
    Postboks 7807
    5020 BERGEN

Association between stress across life and changes in sleep and circadian rhythms, with a translational perspective (animal models and human studies).

I investigate different early life conditions and consequences for health later in life (sleep, circadian rhythms, behavior and cognition), and which factors can moderate the effects of adverse early life events.

Another research focus is on consequences of nightshift-work for sleep, circadian rhythms and waking function. One of the main goals is to investigate how different lighting conditions can be used to alleviate sleepiness and improve cognitive function during nightshift-work and to identify molecular mechanisms.

 

Methods:

Animal models

  • Objective measures of sleep and waking function
  • Objective measures of circadian rhythmicity
  • Electrophysiology
  • Polysomnography
  • Behavioural tests

Human studies

  • Subjective and objective measures of sleep and waking function
  • Subjective and objective measures of circadian rhythmicity
  • Polysomnography
  • Cognitive tests 

Normal barin development (in Norwegian)

Journal SLEEP, p.14-15

 

Sommer school in circadian rhythms and sleep (in Norwegian)

Journal SLEEP, p.35-37

 

What happens with sleep in adolescents and how can we teach about the importance of sleep (in Norwegian)

Journal SLEEP, p.18-22

Course coordinator:

  • Behaviour, health and nutrition PSYK140

Other courses:

  • Biological psychology PROPSY303
  • Circadian rhythms, sleep and behavior PSYK115
  • Development, cognitive and biological psychology PSYK114
  • Circadian rhythms and sleep their role in mental and physical health, safety and productivity (NRSN summer school 2017)

Some topics thet I teach:

  • Neuroanatomi/physiology
  • Development of nervous system
  • Nutrition and brain function
  • Sleep across species
  • Sleep and circadian rhythms across life span
  • Stress regulation

See publication list i PubMed

Journal articles
  • Bjorvatn, Bjørn; Mrdalj, Jelena; Saxvig, Ingvild W.; Aasnæs, Tom; Pallesen, Ståle; Waage, Siri. 2017. Age and sex differences in bedroom habits and bedroom preferences. Sleep Medicine. 32: 157-161. doi: 10.1016/j.sleep.2017.01.003
  • Bjorvatn, Bjørn; Mrdalj, Jelena; Saxvig, Ingvild W.; Aasnes, Tom; Pallesen, Ståle; Waage, Siri. 2016. Use of electronic media in bed and reading in bed after bedtime – Age and sex differences in a representative adult population. Journal of Sleep Research. 25: 377-377. Published 2016-08-29. doi: 10.1111/jsr.12446
  • Grønli, Janne; Meerlo, Peter; Pedersen, Torhild; Pallesen, Ståle; Skrede, Silje; Marti, Andrea Rørvik; Wisor, Jonathan; Murison, Robert; Henriksen, Tone Elise Gjøtterud; Rempe, Michael J.; Mrdalj, Jelena. 2016. A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. Journal of Biological Rhythms. 32: 48-63. doi: 10.1177/0748730416675460
  • Hossain, Jubayer; Ystaas, Lars Andreas Rømo; Mrdalj, Jelena; Välk, Kristjan; Riecken, Kristoffer; Fehse, Boris; Bjerkvig, Rolf; Grønli, Janne; Miletic, Hrvoje. 2016. Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells. Journal of Gene Medicine. 18: 234-243. doi: 10.1002/jgm.2895
  • Marti, Andrea Rørvik; Meerlo, Peter; Grønli, Janne; Hasselt, Sjoerd van; Mrdalj, Jelena; Pallesen, Ståle; Pedersen, Torhild; Henriksen, Tone Elise Gjøtterud; Skrede, Silje. 2016. Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shiftwork: A rat model. Nutrients. 8:712: 1-13. doi: 10.3390/nu8110712
  • Marti, Andrea Rørvik; Mrdalj, Jelena; Skrede, Silje; Pedersen, Torhild Thue; Meerlo, Peter; van Hasselt, Sjoerd Johan; Henriksen, Tone Elise Gjøtterud; Pallesen, Ståle; Murison, Robert; Grønli, Janne. 2016. Simulated night work alters clock gene expression in central and peripheral tissue in rats. Journal of Sleep Research. 25: 57-57. Published 2016-08-29. doi: 10.1111/jsr.12446
  • Mrdalj, Jelena. 2016. Hva skjer med søvn hos ungdom og hvordan kan vi lære dem at søvn er viktig? SØVN. 8: 18-22.
  • Mrdalj, Jelena. 2016. Basalforskning på ESRS 2016. SØVN. 8: 31.
  • Mrdalj, Jelena. 2016. Basalforskning på WorldSleep konferansen 2015. SØVN. 8: 37.
  • Mrdalj, Jelena. 2016. Årets publikasjon 2015. SØVN. 8: 5.
  • Mrdalj, Jelena; Murison, Robert; Soule, Jonathan; Kinn Rød, Anne Marie; Milde, Anne Marita; Pallesen, Ståle; Grønli, Janne. 2016. Mild daily stressors in adulthood may counteract behavioural effects after constant presence of mother during early life. Physiology and Behavior. 165: 313-321. doi: 10.1016/j.physbeh.2016.08.018
  • Rempe, Michael J.; Pedersen, Torhild Thue; Meerlo, Peter; Mrdalj, Jelena; Pallesen, Ståle; Marti, Andrea Rørvik; Wisor, Jonathan; Murison, Robert; Henriksen, Tone Elise Gjøtterud; Grønli, Janne. 2016. A rat model for shiftwork: Effects on sleep architecture and sleep homeostasis. Journal of Sleep Research. 25: 248-249. Published 2016-08-29. doi: 10.1111/jsr.12446
  • Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine; Pallesen, Ståle; Mrdalj, Jelena; Håvik, Bjarte; Soule, Jonathan; Haavik, Jan; Milde, Anne Marita; Skrede, Silje; Murison, Robert; Krystal, John H; Grønli, Janne. 2016. Implication of NOTCH1 Gene in Susceptibility to Anxiety and Depression among Sexual Abuse Victims. Translational psychiatry. doi: 10.1038/tp.2016.248
  • Kinn Rød, Anne Marie; Murison, Robert; Mrdalj, Jelena; Milde, Anne Marita; Jellestad, Finn Konow; Øvernes, Leif Arvid; Grønli, Janne. 2014. Effects of social defeat on sleep and behaviour: Importance of the confrontational behaviour. Physiology and Behavior. 127: 54-63. doi: 10.1016/j.physbeh.2014.01.010
  • Mrdalj, Jelena; Mattson, Åse Lundegaard; Murison, Robert; Jellestad, Finn Konow; Milde, Anne Marita; Pallesen, Ståle; Ursin, Reidun; Bjorvatn, Bjørn; Grønli, Janne. 2014. Hypothermia after chronic mild stress exposure in rats with a history of postnatal maternal separations. Chronobiology International. 31: 252-264. doi: 10.3109/07420528.2013.846351
  • Mrdalj, Jelena. 2013. Normal utvikling av hjernen. SØVN. 1. 14-15.
  • Mrdalj, Jelena; Pallesen, Ståle; Milde, Anne Marita; Jellestad, Finn Konow; Murison, Robert; Ursin, Reidun; Bjorvatn, Bjørn; Grønli, Janne. 2013. Early and later life stress alter brain activity and sleep in rats. PLoS ONE. 8. Published 2013-07-26. doi: 10.1371/journal.pone.0069923
  • Kinn Rød, Anne Marie; Mrdalj, Jelena; Milde, Anne Marita; Jellestad, Finn Konow; Murison, Robert; Øvernes, Leif Arvid; Grønli, Janne. 2012. Sleep architecture, behaviour, corticosterone and acoustic startle response after double exposure to social defeat in rats. Journal of Sleep Research. 21: 212-212.
  • Steine, Iris Mulders; Milde, Anne Marita; Bjorvatn, Bjørn; Grønli, Janne; Nordhus, Inger Hilde; Mrdalj, Jelena; Pallesen, Ståle. 2012. Forekomsten av seksuelle overgrep i et representativt befolkningsutvalg i Norge. Tidsskrift for Norsk Psykologforening. 49: 950-957.
  • Øines, Eliann; Murison, Robert; Mrdalj, Jelena; Grønli, Janne; Milde, Anne Marita. 2012. Neonatal maternal separation in male rats increases intestinal permeability and affects behavior after chronic social stress. Physiology and Behavior. 105: 1058-1066. doi: 10.1016/j.physbeh.2011.11.024
  • Breivik, Lars Ertesvåg; Helgeland, Erik; Aarnes, Eva-Katrine; Mrdalj, Jelena; Jonassen, Anne K. 2011. Remote postconditioning by humoral factors in effluent from ischemic preconditioned rat hearts is mediated via PI3K/Akt-dependent cell-survival signaling at reperfusion. Basic Research in Cardiology. 106: 135-145. doi: 10.1007/s00395-010-0133-0
Reports and theses
  • Mrdalj, Jelena. 2014. The early life condition. Importance for sleep, circadian rhythmicity, behaviour and response to later life challenges. University of Bergen.
  • Mrdalj, Jelena. 2006. Meaning of motivation and spontaneous exploration for the firing properties of place cells in CA1 area of hippocampus: electrophysiological study in freely-moving rats. Institutt for biomedisin, Universitetet i Bergen.

More information in national current research information system (CRIStin)

2015-2017: Associate proffesor - substitute, Department of Biological and Medical Psychology, UiB

2014-2017: Advisor. Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital

2010-2014: PhD, Faculty of Psychology, University of Bergen

2008-2009: Trainee in sleep research, Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital

2004-2006: MSc, human physiology, Department of Biomedicine, University of Bergen