Home
Lars A. Akslen's picture

Lars A. Akslen

Professor, Centre Director of CCBIO
  • E-mailLars.Akslen@uib.no
  • Phone+47 55 97 31 82
  • Visitor Address
    Dept. of Pathology, Sentralblokka 2nd floor, Haukeland University Hospital (HUH)
    or CCBIO, Sentralblokka 2nd floor, Haukeland University Hospital (HUH)
  • Postal Address
    Postboks 7804
    5020 Bergen

Akslen is a certified specialist in surgical pathology and is directing the Tumor Biology Research Group (since the establishment in 1995) at Department of Clinical Medicine (University of Bergen). Since 2013, Akslen is the director of Centre for Cancer Biomarkers CCBIO. Akslen´s team, and now CCBIO, are engaged in translational cancer research with a strong focus on  exploration and validation of novel biomarkers for more biologically based classification and grading of malignant tumors, as a better guide for targeted treatment. The group has included projects on various cancers, such as breast cancer, malignant melanoma, prostate cancer, and gynecologic cancers. Studies of human tumor samples are combined with experimental cell and animal models to improve translation. The overall aim is to provide novel biomarkers which can assist in prediction of aggressive tumor behavior and be helpful in tailored treatment.

Books
  • Akslen, Lars A.; Watnick, Randolph S. 2017. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Springer. 534 pages. ISBN: 978-3-319-39145-8.
Journal articles
  • Aziz, Sura Mohammed; Wik, Elisabeth; Knutsvik, Gøril; Klingen, Tor Audun; Chen, Ying; Davidsen, Benedicte; Aas, Hans; Aas, Turid; Akslen, Lars A. 2017. Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer. PLoS ONE. 12:e0171853: 1-15. doi: 10.1371/journal.pone.0171853
  • Berg, Anna; Gulati, Ankush; Ytre-Hauge, Sigmund; Fasmer, Kristine Eldevik; Mauland, Karen Klepsland; Høivik, Erling Andre; Husby, Jenny Hild Aase; Tangen, Ingvild Løberg; Trovik, Jone; Halle, Mari Kyllesø; Stefansson, Ingunn; Akslen, Lars A.; Woie, Kathrine; Bjørge, Line; Salvesen, Helga; Salvesen, Øyvind; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Krakstad, Camilla. 2017. Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers. OncoTarget. 8: 68530-68541. doi: 10.18632/oncotarget.19708
  • Fang, Jun; Jia, Jinping; Makowski, Matthew; Xu, Mai; Wang, Zhaoming; Zhang, Tongwu; Hoskins, Jason W.; Choi, Jiyeon; Han, Younghun; Zhang, Mingfeng; Thomas, Janelle; Kovacs, Michael; Collins, Irene; Dzyadyk, Marta; Thompson, Abbey; O'Neill, Maura; Das, Sudipto; Lan, Qi; Koster, Roelof; Stolzenberg-Solomon, Rachael S.; Kraft, Peter; Wolpin, Brian M; Jansen, Pascal W. T. C.; Olson, Sara; McGlynn, Katherine A.; Kanetsky, Peter A.; Chatterjee, Nilanjan; Barrett, Jennifer H.; Dunning, Alison M.; Taylor, John C.; Newton-Bishop, Julia A.; Bishop, D Timothy; Andresson, Thorkell; Petersen, Gloria M.; Amos, Christopher I.; Iles, Mark M.; Nathanson, Katherine L; Landi, Maria Teresa; Vermeulen, Michiel; Brown, Kevin M.; Amundadottir, Laufey T.; Molven, Anders; Helsing, Per; Andresen, Per Arne; Rootwelt, Helge; Akslen, Lars A. 2017. Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications. 8:15034: 1-15. doi: 10.1038/ncomms15034
  • Fonnes, Tina; Berg, Hege Fredriksen; Onyango, Therese Bredholt; Edquist, Per-Henrik D.; Sortland, Kristina; Berg, Anna; Salvesen, Helga; Akslen, Lars A.; Werner, Henrica Maria Johanna; Trovik, Jone; Tangen, Ingvild Løberg; Krakstad, Camilla. 2017. Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions. Gynecologic Oncology. 148: 197-203. doi: 10.1016/j.ygyno.2017.10.025
  • Hugdahl, Emilia Signe; Kalvenes, May Britt; Mannelqvist, Monica; Ladstein, Rita Grude; Akslen, Lars A. 2017. Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and secondary cutaneous melanoma. British Journal of Cancer. 118: 98-105. doi: 10.1038/bjc.2017.384
  • Klingen, Tor Audun; Chen, Ying; Aas, Hans; Wik, Elisabeth; Akslen, Lars A. 2017. Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer. Human Pathology. 69: 72-80. doi: 10.1016/j.humpath.2017.09.001
  • Kraby, Maria Ryssdal; Opdahl, Signe; Akslen, Lars A.; Bofin, Anna M. 2017. Quantifying tumour vascularity in non-luminal breast cancers. Journal of Clinical Pathology. 70: 766-774. doi: 10.1136/jclinpath-2016-204208
  • Krüger, Kristi; Wik, Elisabeth; Knutsvik, Gøril; Nalwoga, Hawa; Klingen, Tor Audun; Arnes, Jarle; Chen, Ying; Mannelqvist, Monica; Dimitrakopoulou, Konstantina; Stefansson, Ingunn; Birkeland, Even; Aas, Turid; Tobin, Nicholas P.; Jonassen, Inge; Bergh, Jonas; Foulkes, William D; Akslen, Lars A. 2017. Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer. Scientific Reports. 7:1089: 1-12. doi: 10.1038/s41598-017-00862-w
  • Pilskog, Martin; Beisland, Christian; Akslen, Lars A.; Bostad, Leif; Haug, Åse; Heinrich, Daniel; Hjelle, Karin Margrethe; Straume, Oddbjørn. 2017. Predictive value of C-reactive protein in patients treated with sunitinib for metastatic clear cell renal cell carcinoma. BMC Urology. 17:74: 1-11. doi: 10.1186/s12894-017-0267-6
  • Ramnefjell, Maria; Aamelfot, Christina; Aziz, Sura Mohammed; Helgeland, Lars; Akslen, Lars A. 2017. Microvascular proliferation is associated with aggressive tumour features and reduced survival in lung adenocarcinoma. The journal of pathology. Clinical research. 3: 249-257. doi: 10.1002/cjp2.78
  • Ramnefjell, Maria; Aamelfot, Christina; Helgeland, Lars; Akslen, Lars A. 2017. Low expression of SerpinB2 is associated with reduced survival in lung adenocarcinomas. OncoTarget. 8: 90706-90718. doi: 10.18632/oncotarget.21456
  • Ramnefjell, Maria; Aamelfot, Christina; Helgeland, Lars; Akslen, Lars A. 2017. Vascular invasion is an adverse prognostic factor in resected non?small-cell lung cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 125: 197-206. doi: 10.1111/apm.12652
  • Reisæter, Lars Anders Rokne; Futterer, Jürgen J.; Losnegård, Are; Nygård, Yngve; Monssen, Jan Anker; Gravdal, Karsten; Halvorsen, Ole Johan; Akslen, Lars A.; Biermann, Martin; Haukaas, Svein Andreas; Rørvik, Jarle; Beisland, Christian. 2017. Optimising preoperative risk stratification tools for prostate cancer using mpMRI. European Radiology. 28: 1016-1026. Published 2017-10-06. doi: 10.1007/s00330-017-5031-5
  • Strand, Roger; Akslen, Lars A. 2017. Hva er ansvarlig kreftforskning? Tidsskrift for Den norske legeforening. 137: 292-294. doi: 10.4045/tidsskr.16.0295
  • Tangen, Ingvild Løberg; Venereis, Jennifer Taylor; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Trovik, Jone; Akslen, Lars A.; Salvesen, Helga; Conzen, Suzanne D.; Fleming, Gini F.; Krakstad, Camilla. 2017. Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions. Gynecologic Oncology. 147: 672-677. doi: 10.1016/j.ygyno.2017.09.013
  • Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. 2017. FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis. Breast Cancer Research and Treatment. 162: 243-253. doi: 10.1007/s10549-017-4125-8
  • Aziz, Sura Mohammed; Wik, Elisabeth; Knutsvik, Gøril; Klingen, Tor Audun; Chen, Yingshan; Davidsen, Benedicte; Aas, Hans; Aas, Turid; Akslen, Lars A. 2016. Evaluation of Tumor Cell Proliferation by Ki-67 Expression and Mitotic Count in Lymph Node Metastases from Breast Cancer. PLoS ONE. 11. doi: 10.1371/journal.pone.0150979
  • Frydenberg, Hanne; Thune, Inger; Lofterød, Trygve; Mortensen, Elin Synnøve; Eggen, Anne Elise; Risberg, Terje; Wist, Erik; Flote, Vidar Gordon; Furberg, Anne-Sofie; Wilsgaard, Tom; Akslen, Lars A.; McTiernan, Anne. 2016. Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival. Breast Cancer Research and Treatment. 155: 345-354. doi: 10.1007/s10549-015-3671-1
  • Helsing, Per; Robsahm, Trude Eid; Vos, Linda; Rizvi, Syed Mohammad H.; Akslen, Lars A.; Veierød, Marit Bragelien. 2016. Cutaneous head and neck melanoma (CHNM): A population-based study of the prognostic impact of tumor location. The Journal of American Academy of Dermatology. 75: 975-982.
  • Hofvind, Solveig; Holen, åsne Sørlien; Roman, Martha; Sebuødegård, Sofie; Puig-Vives, M; Akslen, Lars A. 2016. Mode of detection: an independent prognostic factor for women with breast cancer. Journal of Medical Screening. 23: 89-97. doi: 10.1177/0969141315604006
  • Hugdahl, Emilia Signe; Kalvenes, May Britt; Puntervoll, Hanne Eknes; Ladstein, Rita Grude; Akslen, Lars A. 2016. BRAF-V600E expression in primary nodular melanoma is associated with aggressive tumour features and reduced survival. British Journal of Cancer. 114: 801-808. doi: 10.1038/bjc.2016.44
  • Klingen, Tor Audun; Chen, Ying; Stefansson, Ingunn; Knutsvik, Gøril; Collett, Karin; Abrahamsen, Anne Line; Aase, Hildegunn Siv; Aas, Hans; Aas, Turid; Wik, Elisabeth; Akslen, Lars A. 2016. Tumour cell invasion into blood vessels is significantly related to breast cancer subtypes and decreased survival. Journal of Clinical Pathology. 70: 313-319. doi: 10.1136/jclinpath-2016-203861
  • Knutsvik, Gøril; Collett, Karin; Arnes, Jarle; Akslen, Lars A.; Stefansson, Ingunn. 2016. QSOX1 expression is associated with aggressive tumor features and reduced survival in breast carcinomas. Modern Pathology. Dec;29: 1485-1491. doi: 10.1038/modpathol.2016.148
  • Mauland, Karen Klepsland; Wik, Elisabeth; Høivik, Erling Andre; Kusonmano, Kanthida; Halle, Mari Kyllesø; Berg, Anna; Haugland, Hans Kristian; Øyan, Anne Margrete; Kalland, Karl-Henning; Stefansson, Ingunn; Akslen, Lars A.; Krakstad, Camilla; Trovik, Jone; Werner, Henrica Maria Johanna; Salvesen, Helga. 2016. Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival. OncoTarget. 8: 9696-9707. doi: 10.18632/oncotarget.14201
  • Nalwoga, Hawa; Ahmed, Lavina; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2016. Strong expression of hypoxia-inducible factor-1α (HIF-1α) is associated with Axl expression and features of aggressive tumors in African breast cancer. PLoS ONE. 11. doi: 10.1371/journal.pone.0146823
  • Nygård, Yngve; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2016. A positive Real-Time Elastography (RTE) combined with a Prostate Cancer Gene 3 (PCA3) score above 35 convey a high probability of intermediate- or high-risk prostate cancer in patient admitted for primary biopsy. BMC Urology. 16:39: 1-8. doi: 10.1186/s12894-016-0159-1
  • Opsahl, Else Marie; Brauckhoff, Michael; Schlichting, Ellen; Helset, Kristin; Svartberg, Johan; Brauckhoff, Katrin; Mæhle, Lovise Olaug; Engebretsen, Lars Fredri; Sigstad, Eva; Kotanska-Grøholt, Krystyna; Akslen, Lars A.; Jørgensen, Lars Hilmar; Varhaug, Jan Erik; Bjøro, Trine. 2016. A nationwide study of multiple endocrine neoplasia type 2A in Norway: predictive and prognostic factors for the clinical course of medullary thyroid carcinoma. Thyroid. 26: 1225-1238. doi: 10.1089/thy.2015.0673
  • Schuster, Cornelia; Akslen, Lars A.; Straume, Oddbjørn. 2016. Expression of Heat Shock Protein 27 in melanoma metastases is associated with overall response to bevacizumab monotherapy: Analyses of predictive markers in a clinical phase II study. PLoS ONE. 11. doi: 10.1371/journal.pone.0155242
  • Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe. 2016. Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences. Cancer Epidemiology, Biomarkers and Prevention. 25. doi: 10.1158/1055-9965.EPI-16-0427
  • Wang, Suming; Blois, Anna; El Rayes, Tina; Liu, Joyce F.; Hirsch, Michelle S.; Gravdal, Karsten; Palakurthi, Sangeetha; Bielenberg, Diane R.; Akslen, Lars A.; Drapkin, Ronny; Mittal, Vivek; Watnick, Randolph S. 2016. Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment. Science Translational Medicine. 8. doi: 10.1126/scitranslmed.aad5653
  • Ahmed, Lavina; Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Micklem, David Robert; Akslen, Lars A. 2015. Increased tumor cell expression of Axl is a marker of aggressive features in breast cancer among African women. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 123: 688-696. doi: 10.1111/apm.12403
  • Barrett, Jennifer H.; Taylor, John C.; Bright, C; Harland, Mark; Dunning, Alison M; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brossard, Myriam; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Molven, Anders; Novakovic, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; van der Stoep, Nienke; van Doorn, Remco; van Workum, Wilberg; Goldstein, Alisa M.; Kanetsky, Peter A.; Pharoah, Paul D.P.; Demenais, Florence; Hayward, Nicholas K.; Bishop, Julia A. Newton; Bishop, D. Timothy; Iles, Mark M. 2015. Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions. International Journal of Cancer. 136: 1351-1360. doi: 10.1002/ijc.29099
  • Biermann, Martin; Kråkenes, Jostein; Brauckhoff, Katrin; Haugland, Hans Kristian; Heinecke, Achim; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2015. Post-PET ultrasound improves specificity of 18F-FDG-PET for recurrent differentiated thyroid cancer while maintaining sensitivity. Acta Radiologica. 56: 1350-1360. doi: 10.1177/0284185115574298
  • Bredholt, Geir; Mannelqvist, Monica; Stefansson, Ingunn; Birkeland, Even; Bø, Trond Hellem; Øyan, Anne Margrete; Trovik, Jone; Kalland, Karl-Henning; Jonassen, Inge; Salvesen, Helga; Wik, Elisabeth; Akslen, Lars A. 2015. Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses. OncoTarget. 6: 39676-39691. doi: 10.18632/oncotarget.5344
  • Hofvind, Solveig; Holen, Åsne Sørlien; Aas, Turid; Roman, Martha; Sebuødegård, Sofie; Akslen, Lars A. 2015. Women treated with breast conserving surgery do better than those with mastectomy independent of detection mode, prognostic and predictive tumor characteristics. European Journal of Surgical Oncology. 41: 1417-1422. doi: 10.1016/j.ejso.2015.07.002
  • Knappskog, Stian; Berge, Elisabet Ognedal; Chrisanthar, Ranjan; Geisler, Stephanie; Staalesen, Vidar; Leirvaag, Beryl; Yndestad, Synnøve; de Faveri, Elise Norheim; Karlsen, Bård Ove; Wedge, David C.; Akslen, Lars A.; Lilleng, Peer Kåre; Løkkevik, Erik; Lundgren, Steinar; Østenstad, Bjørn; Risberg, Terje; Mjaaland, Ingvil; Aas, Turid; Lønning, Per Eystein. 2015. Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo. Molecular Oncology. 9: 1553-1564. doi: 10.1016/j.molonc.2015.04.008
  • Kraby, Maria Ryssdal; Krüger, Kristi; Opdahl, Signe; Vatten, Lars Johan; Akslen, Lars A.; Bofin, Anna M. 2015. Microvascular proliferation in luminal A and basal-like breast cancer subtypes. Journal of Clinical Pathology. 68: 891-897. doi: 10.1136/jclinpath-2015-203037
  • Law, Matthew H.; Bishop, D. Timothy; Lee, Jeffrey E.; Brossard, Myriam; Martin, Nicholas G.; Moses, Eric; Song, Fengju; Barrett, Jennifer H.; Kumar, Rajiv; Easton, Douglas F.; Pharoah, Paul D.P.; Swerdlow, Anthony J.; Kypreou, Katerina P.; Taylor, John C.; Harland, Mark; Randerson-Moor, Juliette; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brown, Kevin M; Debniak, Tadeusz; Duffy, David L.; Elder, David E.; Fang, Shenying; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hocevar, Marko; Höiom, Veronica; Ingvar, Christian; Kanetsky, Peter A.; Chen, Wei V.; Landi, Maria Teresa; Lang, Julie; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Mann, Graham J.; Molven, Anders; Montgomery, Grant W.; Novakovic, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; Qureshi, Abrar A.; Radford-Smith, Graham L; Van Der Stoep, Nienke; Van Doorn, Remco; Whiteman, David C.; Craig, Jamie E.; Schadendorf, Dirk; Simms, Lisa A.; Burdon, Kathryn P.; Nyholt, Dale R.; Pooley, Karen A.; Orr, Nick; Stratigos, Alexander J.; Cust, Anne E.; Ward, Sarah V.; Hayward, Nicholas K.; Han, Jiali; Schulze, Hans-Joachim; Dunning, Alison M.; Bishop, Julia A. Newton; Demenais, Florence; Amos, Christopher I.; MacGregor, Stuart; Iles, Mark M. 2015. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nature Genetics. 47: 987-995. doi: 10.1038/ng.3373
  • Moshina, Nataliia; Ursin, Giske; Hoff, Solveig Roth; Akslen, Lars A.; Roman, Martha; Sebuødegård, Sofie; Hofvind, Solveig. 2015. Mammographic density and histopathologic characteristics of screen-detected tumors in the Norwegian Breast Cancer Screening Program. Acta radiologica open.
  • Nygård, Yngve; Haukaas, Svein Andreas; Eide, Geir Egil; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2015. Prostate cancer antigen-3 (PCA3) and PCA3-based nomograms in the diagnosis of prostate cancer: an external validation of Hansen's nomogram on a Norwegian cohort. Scandinavian journal of urology. 49: 8-15. doi: 10.3109/21681805.2014.949841
  • Reisæter, Lars Anders Rokne; Fütterer, Jurgen; Halvorsen, Ole Johan; Nygård, Yngve; Biermann, Martin; Andersen, Erling; Gravdal, Karsten; Haukaas, Svein Andreas; Monssen, Jan Anker; Huisman, Henkjan J; Akslen, Lars A.; Beisland, Christian; Rørvik, Jarle. 2015. 1.5-T multiparametric MRI using PI-RADS: a region by region analysis to localize the index-tumor of prostate cancer in patients undergoing prostatectomy. Acta Radiologica. 56: 500-511. doi: 10.1177/0284185114531754
  • Stefansson, Ingunn; Ræder, Maria B; Wik, Elisabeth; Mannelqvist, Monica; Kusonmano, Kanthida; Knutsvik, Gøril; Haldorsen, Ingfrid S.; Trovik, Jone; Øyan, Anne Margrete; Kalland, Karl-Henning; Staff, Anne Cathrine; Salvesen, Helga; Akslen, Lars A. 2015. Increased angiogenesis is associated with a 32-gene expression signature and 6p21 amplification in aggressive endometrial cancer. OncoTarget. 6: 10634-10645. doi: 10.18632/oncotarget.3521
  • Von Dobschuetz, Ernst; Leijon, Helena; Schalin-Jäntti, Camilla; Schiavi, Francesca; Brauckhoff, Michael; Peczkowska, Mariola; Spiazzi, Giovanna; Demattè, Serena; Cecchini, Maria Enrica; Sartorato, Paola; Krajewska, Jolanta; Hasse-Lazar, Kornelia; Roszkowska-Purska, Katarzyna; Taschin, Elisa; Malinoc, Angelica; Akslen, Lars A.; Arola, Johanna; Lange, Dariusz; Fassina, Ambrogio; Pennelli, Gianmaria; Barbareschi, Mattia; Luettges, Jutta; Prejbisz, Aleksander; Januszewicz, Andrzej; Strate, Tim; Bausch, Birke; Castinetti, Frederic; Jarzab, Barbara; Opocher, Giuseppe; Eng, Charis; Neumann, Hartmut P.H. 2015. A registry-based study of thyroid paraganglioma: histologic and genetic characteristics. Endocrine-Related Cancer. 22: 191-204. doi: 10.1530/ERC-14-0558
  • Chen, Ying; Klingen, Tor Audun; Wik, Elisabeth; Aas, Hans; Vigeland, Einar; Liestøl, Knut; Garred, Øystein; Mæhlen, Jan; Akslen, Lars A.; Lømo, Jon. 2014. Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study. Diagnostic Pathology. 9. 8 pages. doi: 10.1186/s13000-014-0230-8
  • Haldorsen, Ingfrid S.; Stefansson, Ingunn; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Taxt, Torfinn; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas. British Journal of Cancer. 110: 107-114. doi: 10.1038/bjc.2013.694
  • Hellesøy, Monica; Blois, Anna; Tiron, Crina Elena; Mannelqvist, Monica; Akslen, Lars A.; Lorens, James. 2014. Akt1 activity regulates vessel maturation in a tissue engineering model of angiogenesis. Tissue Engineering. Part A. 20: 2590-2603. doi: 10.1089/ten.tea.2013.0399
  • Iles, Mark M.; Bishop, D. Timothy; Taylor, John C.; Hayward, Nicholas K.; Brossard, Myriam; Cust, Anne E.; Dunning, Alison M.; Lee, Jeffrey E.; Moses, Eric K.; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Harland, Mark; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Kanetsky, Peter A.; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Martin, Nicholas G.; Molven, Anders; Montgomery, Grant W.; Novakovic, Srdian; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; Radford-Smith, Graham L.; Randerson-Moor, Juliette; Study Group, SDH; van der Stoep, Nienke; van Doorn, Remco; Whiteman, David C.; MacGregor, Stuart; Pooley, Karen A.; Ward, Sarah V.; Mann, Graham J.; Amos, Christopher I.; Pharoah, Paul D.P.; Demenais, Florence; Law, Matthew H.; Bishop, Julia A. Newton; Barrett, Jennifer H. 2014. The effect on melanoma risk of genes previously associated with telomere length. Journal of the National Cancer Institute. 106:dju267. doi: 10.1093/jnci/dju267
  • Knutsvik, Gøril; Stefansson, Ingunn; Aziz, Sura Mohammed; Arnes, Jarle; Eide, Johan; Collett, Karin; Akslen, Lars A. 2014. Evaluation of Ki67 expression across distinct categories of breast cancer specimens: A Population-based study of matched surgical specimens, core needle biopsies and tissue microarrays. PLoS ONE. 9. doi: 10.1371/journal.pone.0112121
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2014. Nestin expression is associated with aggressive cutaneous melanoma of the nodular type. Modern Pathology. 27: 396-401. doi: 10.1038/modpathol.2013.151
  • Lia, Wenliang; Ai, Nanping; Wang, Suming; Bhattacharya, Nandita; Vrbanac, Vladimir; Collins, Michael; Signoretti, Sabina; Hu, Yanhui; Boyce, Frederick M.; Gravdal, Karsten; Halvorsen, Ole Johan; Nalwoga, Hawa; Akslen, Lars A.; Harlow, Ed; Watnick, Randolph S. 2014. GRK3 is essential for metastatic cells and promotes prostate tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 111: 1521-1526. doi: 10.1073/pnas.1320638111
  • Mackay, Helen; Eisenhauer, Elizabeth A.; Kamel-Reid, Suzanne; Tsao, Ming-Sound; Clarke, Blaise; Karakasis, Katherine; Werner, Henrica Maria Johanna; Trovik, Jone; Akslen, Lars A.; Salvesen, Helga Birgitte; Dongsheng, Tu; Oza, Amit M. 2014. Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer. Cancer. 120: 603-610. doi: 10.1002/cncr.28414
  • Mannelqvist, Monica; Wik, Elisabeth; Stefansson, Ingunn; Akslen, Lars A. 2014. An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer. PLoS ONE. 9. doi: 10.1371/journal.pone.0098787
  • Nygård, Yngve; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2014. A positive real-time elastography is an independent marker for detection of high-risk prostate cancers in the primary biopsy setting. BJU International. 113: E90-E97. doi: 10.1111/bju.12401
  • Ojesina, Akinyemi; Lichtenstein, Lee; Freeman, Samuel S.; Pedamallu, Chandra Sekhar; Imaz-Rosshandler, I; Pugh, Trevor J.; Cherniack, Andrew D.; Ambrogio, Lauren; Cibulskis, Kristian; Bertelsen, Bjørn; Romero-Cordoba, S; Treviño, Victor; Vazquez-Santillan, K; Guadarrama, Alberto Salido; Wright, Alexi A.; Rosenberg, Mara W.; Duke, Fujiko; Kaplan, Bethany; Wang, Rui; Nickerson, Elizabeth; Walline, Heather M; Lawrence, Michael S.; Stewart, Chip; Carter, Scott L.; McKenna, Aaron; Rodriguez-Sanchez, Iram P.; Espinosa-Castilla, Magali; Woie, Kathrine; Bjørge, Line; Wik, Elisabeth; Halle, Mari Kyllesø; Høivik, Erling Andre; Krakstad, Camilla; Gabiño, Nayeli Belem; Gómez-Macías, Gabriela; Valdez-Chapa, Lezmes D.; Garza-Rodríguez, Maria Lourdes; Maytorena, German; Vazquez, Jorge; Rodea, Carlos; Cravioto, Adrian; Cortes, Maria L.; Greulich, Heidi; Crum, Christopher P.; Neuberg, Donna S.; Hidalgo-Miranda, Alfredo; Escareno, Claudia Rangel; Akslen, Lars A.; Carey, Thomas E.; Vintermyr, Olav Karsten; Gabriel, Stacey B.; Barrera-Saldana, Hugo A.; Melendez-Zajgla, Jorge; Getz, Gad; Salvesen, Helga Birgitte; Meyerson, Matthew. 2014. Landscape of genomic alterations in cervical carcinomas. Nature. 506: 371-375. doi: 10.1038/nature12881
  • Puntervoll, Hanne Eknes; Molven, Anders; Akslen, Lars A. 2014. Frequencies of KIT and GNAQ mutations in acral melanoma. Journal of cutaneous pathology. 41: 893-894. doi: 10.1111/cup.12382
  • Puntervoll, Hanne Eknes; Molven, Anders; Akslen, Lars A. 2014. Frequency of somatic BRAF mutations in melanocytic lesions from patients in a CDK4 melanoma family. Pigment Cell & Melanoma Research. 27: 149-151. doi: 10.1111/pcmr.12191
  • Rogers, Michael S.; Novak, Katherine; Zurakowski, David; Cryan, Lorna M.; Blois, Anna; Lifshits, Eugene; Bø, Trond; Øyan, Anne Margrete; Bender, Elise R.; Lampa, Michael; Kang, Soo-Young; Naxerova, Kamila; Kalland, Karl-Henning; Straume, Oddbjørn; Akslen, Lars A.; Watnick, Randolph S.; Folkman, Judah; Naumov, George N. 2014. Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Molecular Cancer Research. 12: 754-764. doi: 10.1158/1541-7786.MCR-13-0532-T
  • Shahrabi-Farahani, Shokoufeh; Wang, Lili; Zwaans, Bernadette MM; Santana, Jeans M; Shimizu, Akio; Takashima, Seiji; Kreuter, Michael; Coultas, Leigh; D'Amore, Patricia A; Arbeit, Jeffrey M.; Akslen, Lars A.; Bielenberg, Diane R. 2014. Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas. Laboratory Investigation. 94: 752-765. doi: 10.1038/labinvest.2014.66
  • Tangen, Ingvild Løberg; Krakstad, Camilla; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Rodriguez, Antoni Hurtado; Salvesen, Helga Birgitte. 2014. Switch in FOXA1 status associates with endometrial cancer progression. PLoS ONE. 9. doi: 10.1371/journal.pone.0098069
  • Werner, Henrica Maria Johanna; Trovik, Jone; Halle, Mari Kyllesø; Wik, Elisabeth; Akslen, Lars A.; Birkeland, Even; Bredholt, Therese; Tangen, Ingvild Løberg; Krakstad, Camilla; Salvesen, Helga Birgitte. 2014. Stathmin Protein Level, a Potential Peredictive Marker for Taxane Treatment Response in Endometrial Cancer. PLoS ONE. 9. doi: 10.1371/journal.pone.0090141
  • Wik, Elisabeth; Trovik, Jone; Kusonmano, Kanthida; Birkeland, Even; Ræder, Maria B; Pashtan, I; Høivik, Erling Andre; Krakstad, Camilla; Werner, Henrica Maria Johanna; Holst, Frederik; Mjøs, Siv; Halle, Mari Kyllesø; Mannelqvist, Monica; Mauland, Karen Klepsland; Øyan, Anne Margrete; Stefansson, Ingunn; Petersen, Kjell; Simon, R; Cherniack, AD; Meyerson, M; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations. Gynecologic Oncology. 134: 599-606. doi: 10.1016/j.ygyno.2014.06.026
  • Arnesen, Thomas; Glomnes, Nina; Strømsøy, Siri S.; Knappskog, Stian; Heie, Anette; Akslen, Lars A.; Grytaas, Marianne Aardal; Varhaug, Jan Erik; Gimm, Oliver; Brauckhoff, Michael. 2013. Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway. Langenbeck's archives of surgery (Print). 398: 869-874. doi: 10.1007/s00423-013-1093-2
  • Catena, Raúl; Bhattacharya, Nandita; El Rayes, Tina; Wang, Suming; Choi, Hyejin; Gao, Dingcheng; Ryu, Seongho; Joshi, Natasha; Bielenberg, Diane; Lee, Sharrell B.; Haukaas, Svein Andreas; Gravdal, Karsten; Halvorsen, Ole Johan; Akslen, Lars A.; Watnick, Randolph S.; Mittal, Vivek. 2013. Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discovery. 3: 578-589. doi: 10.1158/2159-8290.CD-12-0476
  • Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. 2013. Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients. Breast Cancer Research and Treatment. 140: 463-473. doi: 10.1007/s10549-013-2647-2
  • Garcia-Dios, Diego A; Lambrechts, Diether; Coenegrachts, Lieve; Vandenput, Ingrid; Capoen, An; Webb, Penelope M.; Ferguson, Kaltin; Akslen, Lars A.; Claes, Bart; Vergote, Ignace; Moerman, Philippe; Robays, Johan Van; Marcickiewicz, Janusz; Salvesen, Helga Birgitte; Spurdle, Amanda B; Amant, Frédéric. 2013. High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma. Gynecologic Oncology. 128: 327-334. doi: 10.1016/j.ygyno.2012.11.037
  • Geisler, Jürgen; Bachmann, Ingeborg M.; Nyakas, Marta Sølvi; Helsing, Per; Fjøsne, Hans E.; Mæhle, Lovise Olaug; Aamdal, Steinar; Eide, Nils; Svendsen, Henrik Løvendahl; Straume, Oddbjørn; Robsahm, Trude Eid; Dolven-Jacobsen, Kari; Akslen, Lars A. 2013. Malignt melanom – diagnostikk, behandling og oppfølging i Norge. Tidsskrift for Den norske legeforening. 133: 2154-2159. doi: 10.4045/tidsskr.12.1416
  • Haldorsen, Ingfrid S.; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Stefansson, Ingunn Marie; Akslen, Lars A.; Trovik, Jone; Taxt, Torfinn; Salvesen, Helga Birgitte. 2013. Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence. European Radiology. 23: 2916-2925. doi: 10.1007/s00330-013-2901-3
  • Hoem, Dag; Straume, Oddbjørn; Immervoll, Heike; Akslen, Lars A.; Molven, Anders. 2013. Vascular proliferation is associated with survival in pancreatic ductal adenocarcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 121: 1037-1046. doi: 10.1111/apm.12057
  • Iles, Mark M.; Law, Matthew H.; Stacey, Simon N.; Han, Jiali; Fang, Shenying; Pfeiffer, Ruth; Harland, Mark; MacGregor, Stuart; Taylor, John C.; Aben, Katja K.; Akslen, Lars A.; Avril, Marie Françoise; Azizi, Esther; Bakker, Bert; Benediktsdottir, Kristun R.; Bergman, Wilma; Scarra, Giovanna Bianchi; Brown, Kevin M.; Calista, Donato; Chaudru, Valerie; Fargnoli, Marie Concetta; Cust, Anne E.; Demenais, Florence; de Waal, Anne C.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Hopper, John L.; Ingvar, Christian; Janssen, Marjolein; Jenkins, Mark A.; Kanetsky, Peter A.; Kiemeney, Lambertus A.; Lang, Julie L.; Lathrop, G. Mark; Leachman, Sancy; Lee, Jeffrey E.; Lubiński, Jan; Mackie, Rona M.; Mann, Graham J.; Martin, Nicholas G.; Mayordomo, Jose Ignacio; Molven, Anders; Mulder, Suzanne; Nagore, Eduardo; Novakovic, Srdjan; Okamoto, Ichiro; Olafsson, Jon H.; Olsson, Håkan; Pehamberger, Hubert; Peris, Ketty; Grasa, Maria Pilar; Planelles, Dolores; Puig, Susana; Puig-Butille, Joan Anton; Randerson-Moor, Juliette; Requena, Celia; Rivoltini, Licia; Rodolfo, Monica; Santinami, Mario; Sigurgeirsson, Bardur; Snowden, Helen; Song, Fengju; Sulem, Patrick; Thorisdottir, Kristin; Tuominen, Rainer; Van Belle, Patricia; van der Stoep, Nienke; van Rossum, Michelle M.; Wei, Qingyi; Wendt, Judith; Zelenika, Diane; Zhang, Mingfeng; Landi, Maria Teresa; Thorleifsson, Gudmar; Bishop, D. Timothy; Amos, Christopher I.; Hayward, Nicholas K.; Stefansson, Kari; Bishop, Julia A. Newton; Barrett, Jennifer H. 2013. A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics. 45: 428-432. doi: 10.1038/ng.2571
  • Klingen, Tor Audun; Chen, Ying; Suhrke, Pål; Stefansson, Ingunn Marie; Gundersen, Marian D.; Akslen, Lars A. 2013. Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas. Diagnostic Pathology. 8. doi: 10.1186/1746-1596-8-80
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and mitotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Modern Pathology. 26: 50A-50A.
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and Mimtotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Laboratory Investigation. 93: 50A-50A.
  • Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Bofin, Anna M.; Engebråten, Olav; Mælandsmo, Gunhild; Akslen, Lars A.; Gribbestad, Ingrid S. 2013. Low-molecular contrast agent DCE-MRI and DW-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Journal of Magnetic Resonance Imaging. 38: 1043-1053. Published 2013-01-17. doi: 10.1002/jmri.24079
  • Ozhand, Ali; Lee, Eunjung; Wu, Anna H.; Ellingjord-Dale, Merete; Akslen, Lars A.; McKean-Cowdin, Roberta; Ursin, Giske. 2013. Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55. PLoS ONE. 8. 8 pages. doi: 10.1371/journal.pone.0065313
  • Pedersen, Torbjørn Østvik; Blois, Anna; Xing, Zhe; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Akslen, Lars A.; Lorens, James; Leknes, Knut N.; Fristad, Inge; Mustafa, Kamal Babikeir Eln. 2013. Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs. Stem Cell Research & Therapy. 4. 10 pages. doi: 10.1186/scrt202
  • Puntervoll, Hanne Eknes; Yang, Xiaohong R.; Vetti, Hildegunn Høberg; Bachmann, Ingeborg M.; Avril, Marie Françoise; Benfodda, Meriem; Catricala, Caterina; Dalle, Stéphane; Duval-Modeste, Anne B.; Ghiorzo, Paola; Grammatico, Paola; Harland, Mark; Hayward, Nicholas K.; Hu, Hui-Han; Jouary, Thomas; Martin-Denavit, Tanguy; Ozola, Aija; Palmer, Jane M.; Pastorino, Lorenza; Pjanova, Dace; Soufir, Nadem; Steine, Solrun; Stratigos, Alexander J.; Thomas, Luc; Tinat, Julie; Tsao, Hensin; Veinalde, Rūta; Tucker, Margaret A.; Bressac-de Paillerets, Brigitte B.D.; Newton-Bishop, Julia A.; Goldstein, Alisa M.; Akslen, Lars A.; Molven, Anders. 2013. Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants. Journal of Medical Genetics. 50: 264-U82. doi: 10.1136/jmedgenet-2012-101455
  • Ræder, Maria B; Birkeland, Even; Trovik, Jone; Krakstad, Camilla; Shehata, Shyemaa; Schumacher, Steven; Zack, Travis I.; Krohn, Antje; Werner, Henrica Maria Johanna; Moody, Susan E.; Wik, Elisabeth; Stefansson, Ingunn Marie; Holst, Frederik; Øyan, Anne Margrete; Tamayo, Pablo; Mesirov, Jill P.; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Beroukhim, Rameen; Salvesen, Helga Birgitte. 2013. Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. PLoS ONE. 8. 9 pages. doi: 10.1371/journal.pone.0054873
  • Tangen, Ingvild Løberg; Krakstad, Camilla; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Gilfillan, Siv; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Hurtado, A; Salvesen, Helga Birgitte. 2013. FOXA1 LOSS IN ENDOMETRIAL CANCER IS ASSOCIATED WITH POOR PROGNOSIS AND ER ALPHA LOSS. International Journal of Gynecological Cancer. 23. 1 pages.
  • Trovik, Jone; Wik, Elisabeth; Werner, Henrica Maria Johanna; Krakstad, Camilla; Helland, Harald; Vandenput, Ingrid; Njølstad, Tormund Salvesen; Stefansson, Ingunn; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial. European Journal of Cancer. 49: 3431-3441. doi: 10.1016/j.ejca.2013.06.016
  • Veinalde, Rūta; Ozola, Aija; Azarjana, Kristine; Molven, Anders; Akslen, Lars A.; Donina, Simona; Proboka, Guna; Cema, Ingrida; Baginskis, Ainars; Pjanova, Dace. 2013. Analysis of Latvian familial melanoma patients shows novel variants in the noncoding regions of CDKN2A and that the CDK4 mutation R24H is a founder mutation. Melanoma research. 23: 221-226. doi: 10.1097/CMR.0b013e3283608695
  • Werner, Henrica Maria Johanna; Berg, Anna; Wik, Elisabeth; Birkeland, Even; Krakstad, Camilla; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Øyan, Anne Margrete; Akslen, Lars A.; Trovik, Jone; Salvesen, Helga Birgitte. 2013. ARID1A loss is prevalent in endometrial hyperplasia with atypia and low-grade endometrioid carcinomas. Modern Pathology. 26: 428-434. doi: 10.1038/modpathol.2012.174
  • Wik, Elisabeth; Birkeland, Even; Trovik, Jone; Werner, Henrica Maria Johanna; Høivik, Erling Andre; Mjøs, Siv; Krakstad, Camilla; Kusonmano, Kanthida; Mauland, Karen Klepsland; Stefansson, Ingunn Marie; Holst, Frederik; Petersen, Kjell; Øyan, Anne Margrete; Simon, Roland; Kalland, Karl-Henning; Ricketts, William; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. High phospho-stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition. Clinical Cancer Research. 19: 2331-2341. doi: 10.1158/1078-0432.CCR-12-3413
  • Wik, Elisabeth; Ræder, Maria B; Krakstad, Camilla; Trovik, Jone; Birkeland, Even; Høivik, Erling Andre; Mjøs, Siv; Werner, Henrica Maria Johanna; Mannelqvist, Monica; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Lack of estrogen receptor-alpha is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma. Clinical Cancer Research. 19: 1094-1105. doi: 10.1158/1078-0432.CCR-12-3039
  • Arnes, Jarle; Stefansson, Ingunn Marie; Straume, Oddbjørn; Baak, Jan P.A.; Lønning, Per Eystein; Foulkes, William D.; Akslen, Lars A. 2012. Vascular proliferation is a prognostic factor in breast cancer. Breast Cancer Research and Treatment. 133: 501-510. doi: 10.1007/s10549-011-1785-7
  • Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, R; Krakstad, Camilla; Salvesen, Helga Birgitte. 2012. KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer. British Journal of Cancer. 107: 1997-2004. doi: 10.1038/bjc.2012.477
  • Brauckhoff, Michael; Varhaug, Jan Erik; Hauptmann, Steffen; Akslen, Lars A.; Thanh, P. Nguyen; Viste, Asgaut; Heie, Anette; Dralle, Henning. 2012. Peritoneal carcinosis in apparently benign cortisol producing adrenal adenoma >= 5 cm in diameter: the need of regular postoperative surveillance. Experimental and clinical endocrinology & diabetes. 120: 472-476. doi: 10.1055/s-0032-1321807
  • Ellingjord-Dale, Merete; Lee, Eunjung; Couto, Elisabeth; Ozhand, Ali; Qureshi, Samera Azeem; Hofvind, Solveig; Van Den Berg, David J; Akslen, Lars A.; Grotmol, Tom; Ursin, Giske. 2012. Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users. Breast Cancer Research. 14. doi: 10.1186/bcr3337
  • Helsing, Per; Nymoen, Dag Andre; Rootwelt, Helge; Vårdal, Mari H; Akslen, Lars A.; Molven, Anders; Andresen, Per Arne. 2012. MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. Genes, Chromosomes and Cancer. 51: 654-661. doi: 10.1002/gcc.21952
  • Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita Maria; Bathen, Tone Frost; Nalwoga, Hawa; Krüger, Kristi; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebråten, Olav; Gribbestad, Ingrid S. 2012. In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts. Journal of Magnetic Resonance Imaging. 35: 1098-1107. doi: 10.1002/jmri.23507
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2012. Prognostic impact of proliferation markers Ki-67, PHH3 and mitotic count in breast carcinomas. Virchows Archiv. 461: S5-S5.
  • Krakstad, Camilla; Trovik, Jone; Wik, Elisabeth; Engelsen, Ingeborg Bøe; Werner, Henrica Maria Johanna; Birkeland, Even; Ræder, Maria B; Øyan, Anne Margrete; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2012. Loss of GPER identifies new targets for therapy among a subgroup of ER alpha-positive endometrial cancer patients with poor outcome. British Journal of Cancer. 106: 1682-1688. doi: 10.1038/bjc.2012.91
  • Krüger, Kristi; Stefansson, Ingunn Marie; Collett, Karin; Arnes, Jarle; Aas, Turid; Akslen, Lars A. 2012. Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer. Breast. 1-7. doi: 10.1016/j.breast.2012.07.008
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Tumor necrosis is a prognostic factor in thick cutaneous melanoma. American Journal of Surgical Pathology. 36: 1477-1482. doi: 10.1097/PAS.0b013e31825a5b45
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Prognostic Importance of the Mitotic Marker Phosphohistone H3 in Cutaneous Nodular Melanoma. Journal of Investigative Dermatology. 132: 1247-1252. doi: 10.1038/jid.2011.464
  • Lindholm, Evita Maria; Kristian, Alexandr; Nalwoga, Hawa; Kruger, Kristi; Nygård, Ståle; Akslen, Lars A.; Mælandsmo, Gunhild; Engebråten, Olav. 2012. Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal- and luminal-like breast cancer xenografts. Molecular Oncology. 6: 418-427. doi: 10.1016/j.molonc.2012.03.006
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Wik, Elisabeth; Kusonmano, Kanthida; Ræder, Maria B; Øyan, Anne Margrete; Kalland, Karl-Henning; Moses, Marsha A.; Salvesen, Helga Birgitte; Akslen, Lars A. 2012. Lipocalin 2 expression is associated with aggressive features of endometrial cancer. BMC Cancer. 12. 7 pages. doi: 10.1186/1471-2407-12-169
  • Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug. 2012. Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 12. 10 pages. doi: 10.1186/1471-2407-12-21
  • Moestue, Siver Andreas; Flatabø, Silje; Huuse, Else Marie; Lindholm, Evita Maria; Engebraaten, Olav; Maelandsmo, Gunnhild M; Akslen, Lars A.; Gribbestad, Ingrid S. 2012. Metabolic Responses to VEGF Inhibition in Patient-derived Breast Cancer Xenografts. European Journal of Cancer. 48: S32-S32.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2012. Expression of hypoxia-inducible factor-1a and associations with vascular endothelial growth factor expression, high microvessel density and features of aggressive tumors in African breast cancer. Virchows Archiv. 461: S249-S249.
  • Nygård, Yngve; Haukaas, Svein Andreas; Waage, Jo Erling Riise; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2012. Combination of real-time elastography and urine prostate cancer gene 3 (PCA3) detects more than 97 % of significant prostate cancers. Scandinavian Journal of Urology and Nephrology. 47: 211-216. doi: 10.3109/00365599.2012.727859
  • Schuster, Cornelia; Eikesdal, Hans Petter; Puntervoll, Hanne Eknes; Geisler, Jürgen; Geisler, Stephanie; Heinrich, Daniel; Molven, Anders; Lønning, Per Eystein; Akslen, Lars A.; Straume, Oddbjørn. 2012. Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension. PLoS ONE. 7. 8 pages. doi: 10.1371/journal.pone.0038364
  • Straume, Oddbjørn; Shimamura, Takeshi; Lampa, Michael J.G.; Carretero, Julian; Øyan, Anne Margrete; Jia, Di; Borgman, Christa L.; Soucheray, Margaret; Downing, Sean R.; Short, Sarah M.; Kang, Soo-Young; Wang, Suoming; Chen, Liang; Collett, Karin; Bachmann, Ingeborg M.; Wong, Kwok-Kin; Shapiro, Geoffrey I.; Kalland, Karl-Henning; Folkman, Judah; Watnick, Randolph S.; Akslen, Lars A.; Naumov, George N. 2012. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 8699-8704. doi: 10.1073/pnas.1017909109
  • Wik, Elisabeth; Rader, Maria; Krakstad, Camilla; Trovik, Jone; Erling, Hoivik; Mjøs, Siv; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2012. Estrogen receptor a loss in endometrial carcinoma is associated with epithelial-to-mesenchymal transition and a potential for PI3Kinase inhibition. Virchows Archiv. 461: S18-S18.
  • Akslen, Lars A.; Straume, Oddbjørn; Geisler, Stephanie; Sørlie, Therese; Chi, Jen-Tan Ashley; Aas, Turid; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 2011. Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer. British Journal of Cancer. 105: 9-12. doi: 10.1038/bjc.2011.203
  • Barrett, Jennifer H.; Iles, MM; Harland, M; Taylor, JC; Aitken, JF; Andresen, Per Arne; Akslen, Lars A.; Armstrong, BK; Avril, MF; Azizi, E; Bakker, B; Bergman, W; Bianchi-Scarra, G; Bressac-de Paillerets, B; Calista, D; Cannon-Albright, LA; Corda, E; Cust, AE; Debniak, T; Duffy, D; Dunning, AM; Easton, DF; Friedman, E; Galan, P; Ghiorzo, P; Giles, GG; Hansson, J; Hocevar, M; Hoiom, V; Hopper, JL; Ingvar, C; Janssen, B; Jenkins, MA; Jonsson, G; Kefford, RF; Landi, G; Landi, MT; Lang, J; Lubinski, J; Mackie, R; Malvehy, J; Martin, NG; Molven, Anders; Montgomery, GW; van Nieuwpoort, FA; Novakovic, S; Olsson, H; Pastorino, L; Puig, S; Puig-Butille, JA; Randerson-Moor, J; Snowden, H; Tuominen, R; VanBelle, P; van der Stoep, N; Whiteman, DC; Zelenika, D; Han, JL; Fang, SY; Lee, JE; Wei, QY; Lathrop, GM; Gillanders, EM; Brown, KM; Goldstein, AM; Kanetsky, PA; Mann, GJ; MacGregor, S; Elder, DE; Amos, CI; Hayward, NK; Gruis, NA; Demenais, F; Bishop, JAN; Bishop, D. Timothy. 2011. Genome-wide association study identifies three new melanoma susceptibility loci. Nature Genetics. 43: 1108-U98. doi: 10.1038/ng.959
  • Hegen, Anja; Blois, Anna; Tiron, Crina Elena; Hellesøy, Monica; Micklem, David Robert; Nör, Jacques E; Akslen, Lars A.; Lorens, James. 2011. Efficient in vivo vascularization of tissue-engineering scaffolds. Journal of Tissue Engineering and Regenerative Medicine. 5: E52-E62. doi: 10.1002/term.336
  • Ke, Xisong; Li, Wencheng; Hovland, Randi; Qu, Yi; Liu, Run-hui; McCormack, Emmet Martin; Thorsen, Frits Alan; Olsen, Jan Roger; Molven, Anders; Kogan-Sakin, Ira; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2011. Reprogramming of cell junction modules during stepwise epithelial to mesenchymal transition and accumulation of malignant features in vitro in a prostate cell model. Experimental Cell Research. 317: 234-247. doi: 10.1016/j.yexcr.2010.10.009
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Bredholt, Geir; Bø, Trond Hellem; Øyan, Anne Margrete; Jonassen, Inge; Kalland, Karl-Henning; Salvesen, Helga Birgitte; Akslen, Lars A. 2011. Gene Expression Patterns Related to Vascular Invasion and Aggressive Features in Endometrial Cancer. American Journal of Pathology. 178: 861-871. doi: 10.1016/j.ajpath.2010.10.040
  • Mauland, Karen Klepsland; Trovik, Jone; Wik, Elisabeth; Ræder, Maria B; Njølstad, Tormund Salvesen; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Bjørge, Tone; Akslen, Lars A.; Salvesen, Helga Birgitte. 2011. High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer. British Journal of Cancer. 104: 921-926. doi: 10.1038/bjc.2011.46
  • Myklebust, Line Merethe; Akslen, Lars A.; Varhaug, Jan Erik; Lillehaug, Johan R. 2011. Receptor for Activated Protein C Kinase 1 (RACK1) Is Overexpressed in Papillary Thyroid Carcinoma. Thyroid. 21: 1217-1225. doi: 10.1089/thy.2010.0186
  • Nalwoga, Hawa; Arnes, Jarle; Stefansson, Ingunn Marie; Wabinga, Henry; Foulkes, William D.; Akslen, Lars A. 2011. Vascular proliferation is increased in basal-like breast cancer. Breast Cancer Research and Treatment. 130: 1063-1071. doi: 10.1007/s10549-011-1740-7
  • Tiron, Crina Elena; Gjerdrum, Christine; Høiby, Torill; Maugen, Hallvard; Stefansson, Ingunn Marie; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2011. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Clinical and Experimental Metastasis. 28: 234-235.
  • Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Njølstad, Tormund Salvesen; Vandenput, Ingrid; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte; Ellstrøm Engh, Marie; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik. 2011. Stathmin Overexpression Identifies High-Risk Patients and Lymph Node Metastasis in Endometrial Cancer. Clinical Cancer Research. 17: 3368-3377. doi: 10.1158/1078-0432.CCR-10-2412
  • Vandenput, Ingrid; Trovik, Jone; Leunen, Karin; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Moerman, Philippe; Vergote, Ignace; Salvesen, Helga Birgitte; Amant, Frédéric. 2011. Evolution in endometrial cancer evidence from an immunohistochemical study. International Journal of Gynecological Cancer. 21: 316-322. doi: 10.1097/IGC.0b013e31820575f5
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2010. Multimodal imaging of differentiated thyroid cancer: FDG-PET-CT, I-131-SPECT-CT and ultrasound [Abstract]. European Journal of Nuclear Medicine and Molecular Imaging. 37: S291-S291.
  • Blows, Fiona M.; Driver, Kristy E.; Schmidt, Marjanka K.; Broeks, Annegien; van Leeuwen, Fllora E.; Wesseling, Jelle; Cheang, Maggie C.U.; Gelmon, Karen; Nielsen, Torsten O.; Blomqvist, Carl; Heikkila, Päivi; Heikkinen, Tuomas; Nevanlinna, Heli; Akslen, Lars A.; Bégin, Louis R.; Foulkes, William D.; Couch, Fergus J.; Wang, Xianshu; Cafourek, Vicky; Olson, Janet E.; Baglietto, Laura; Giles, Graham G.; Severi, Gianluca; McLean, Catriona A.; Southey, Melissa C.; Rakha, Emad A.; Green, Andrew R.; Ellis, Ian O.; Sherman, Mark E.; Lissowska, Jolanta; Anderson, William F.; Cox, Angela; Cross, Simon S.; Reed, Malcolm W.R.; Provenzano, Elena; Dawson, Sarah-Jane; Dunning, Alison M.; Humphreys, Manjeet; Easton, Douglas F.; García-Closas, Montserrat; Caldas, Carlos; Pharoah, Paul D.; Huntsman, David G. 2010. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies. PLoS Medicine. 7. 12 pages. doi: 10.1371/journal.pmed.1000279
  • Gjerdrum, Christine; Tiron, Crina Elena; Høiby, Torill; Stefansson, Ingunn Marie; Haugen, Hallvard; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2010. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proceedings of the National Academy of Sciences of the United States of America. 107: 1124-1129. doi: 10.1073/pnas.0909333107
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2010. Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma. BMC Cancer. 10. 15 pages. doi: 10.1186/1471-2407-10-140
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2010. Expression of aldehyde dehydrogenase a (ALDH1) is associated with basal-like markers and features of aggressive tumors in African breast cancer. British Journal of Cancer. 102: 369-375. doi: 10.1038/sj.bjc.6605488
  • Stefansson, Ingunn Marie; Mannelquist, M; Salvesen, HB; Akslen, Lars A. 2010. Prognostic importance of vascular proliferation and tumor cell invasion in blood and lymphatic vessels in endometrial carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 118: 248-248.
  • Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Carter, Scott L.; Beroukhim, Rameen; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2010. Stathmin is superior to AKT and phospho-AKT staining for the detection of phosphoinositide 3-kinase activation and aggressive endometrial cancer. Histopathology. 57: 641-646. doi: 10.1111/j.1365-2559.2010.03661.x
  • Arnes, Jarle; Begin, LR; Brunet, JS; Nielsen, TO; Foulkes, WD; Akslen, Lars A.; Akslen, LA. 2009. Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer. Journal of Clinical Pathology. 62: 139-146. doi: 10.1136/jcp.2008.056291
  • Bhriain, Hannah Ni; Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Salvesen, Helga Birgitte; Staff, Anne Cathrine. 2009. Plasma calprotectin concentrations in women with endometrial carcinoma. Gynecologic Oncology. 114: 491-495. doi: 10.1016/j.ygyno.2009.06.008
  • Bruland, Ove; Fluge, Øystein; Akslen, Lars A.; Eiken, Hans Geir; Lillehaug, Johan R.; Varhaug, Jan Erik; Knappskog, Per Morten. 2009. Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas. BMC Cancer. 9: 425. doi: 10.1186/1471-2407-9-425
  • Engelsen, Ingeborg Bøe; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Biologic markers in endometrial cancer treatment. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 693-707. doi: 10.1111/j.1600-0463.2009.02467.x
  • Etemadmoghadam, Dariush; deFazio, Anna; Beroukhim, Rameen; Mermel, Craig; George, Joshy; Getz, Gad; Tothill, Richard; Okamoto, Aikou; Ræder, Maria Therese Barøy; Harnett, Paul; Lade, Stephen; Akslen, Lars A.; Tinker, Anna V.; Locandro, Bianca; Alsop, Kathryn; Chiew, Yoke-Eng; Traficante, Nadia; Fereday, Sian; Johnson, Daryl; Fox, Stephen; Sellers, William R.; Urashima, Mitsuyoshi; Salvesen, Helga Birgitte; Meyerson, Matthew; Bowtell, David. 2009. Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas. Clinical Cancer Research. 15: 1417-1427. doi: 10.1158/1078-0432.CCR-08-1564
  • Fluge, Øystein; Gravdal, K; Carlsen, E; Carlsen, Erik; Vonen, Barthold; Kjellevold, K; Refsum, S; Lilleng, R; Eide, Tor J.; Halvorsen, TB; Tveit, KM; Tveit, Kjell Magne; Otte, AP; Akslen, LA; Dahl, O. 2009. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. British Journal of Cancer. 101: 1282-1289. doi: 10.1038/sj.bjc.6605333
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer. Cancer Research. 69: 4708-4715. doi: 10.1158/0008-5472.CAN-08-4417
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progress in prostate cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 233-233. doi: 10.1111/j.1600-0463.2009.02434.x
  • Kang, Soo-Young; Halvorsen, Ole Johan; Gravdal, Karsten; Bhattacharya, Nandita; Lee, Jung Min; Liu, Nathan W.; Johnston, Brian T.; Johnston, Adam B.; Haukaas, Svein Andreas; Aamodt, Kristie; Yoo, Sun; Akslen, Lars A.; Watnick, Randolph S. 2009. Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 12115-12120. doi: 10.1073/pnas.0903120106
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Li, Wen-Cheng; Lin, Biaoyang; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Jonassen, Inge; Petersen, Kjell; Goldfinger, Naomi; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. Genome-wide profiling of histone H3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis. PLoS ONE. 4. 14 pages. doi: 10.1371/journal.pone0004687
  • Klingen, Tor A; Klaasen, Heman; Aas, Hans; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 762-767. doi: 10.1111/j.1600-0463.2009.02529.x
  • Klingen, Tor Audun; Klaasen, Herman; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 762-767. doi: 10.1111/j.1600-0463.2009.02529.x
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Salvesen, Helga Birgitte; Akslen, Lars A. 2009. Importance of tumour cell invasion in blood and lymphatic vasculature among patients with endometrial carcinoma. Histopathology. 54: 174-183. doi: 10.1111/j.1365-2559.2008.03201.x
  • Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2009. Hyperoxic treatment induces mesenchymal to epithelial transition in a rat adenocarcinoma model. PLoS ONE. 4. doi: 10.1371/journal.pone.0006381
  • Mæhle, BO; Mæhle, Bjørn Ove; Collett, Karin; Tretli, Steinar; Akslen, Lars A.; Grotmol, Tom. 2009. Estrogen receptor β– an independent prognostic marker in estrogen receptor α and progesterone receptor-positive breast cancer? Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 644-650. doi: 10.1111/j.1600-0463.2009.02510.x
  • Naumov, George N.; Nilsson, Monique B.; Cascone, Tina; Briggs, Alexandra; Straume, Oddbjørn; Akslen, Lars A.; Lifshits, Eugene; Byers, Lauren Averett; Xu, Li; Wu, Hua-kang; Jänne, Pasi; Kobayashi, Susumu; Halmos, Balazs; Tenen, Daniel; Tang, Xi M.; Engelman, Jeffrey; Yeap, Beow; Folkman, Judah; Johnson, Bruce E.; Heymach, John V. 2009. Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clinical Cancer Research. 15: 3484-3494. doi: 10.1158/1078-0432.CCR-08-2904
  • Pjanova, Dace; Molven, Anders; Akslen, Lars A.; Engele, Ludmila; Streinerte, Baiba; Azarjana, Kristine; Heisele, Olita. 2009. Identification of a CDK4 R24H mutation-positive melanoma family by analysis of early-onset melanoma patients in Latvia. Melanoma research. 19: 119-122. doi: 10.1097/CMR.0b013e3283287d3e
  • Rakha, Emad A.; Elsheikh, Somaia E.; Aleskandarany, Muhammed A.; Habashi, Hany O.; Green, Andrew R.; Powe, Desmond G.; El-Sayed, Maysa E.; Benhasouna, Ahmed; Brunet, Jean-Sébastien; Akslen, Lars A.; Evans, Andy J.; Blamey, Roger; Reis-Filho, Jorge S.; Foulkes, William D.; Ellis, Ian O. 2009. Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes. Clinical Cancer Research. 15: 2302-2310. doi: 10.1158/1078-0432.CCR-08-2132
  • Rostad, Kari; Hellwinkel, Olaf JC; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Øyan, Anne Margrete; Haese, Alexander; Budäus, Lars; Albrecht, Heiko; Akslen, Lars A.; Schlomm, Thorsten; Kalland, Karl-Henning. 2009. TMPRSS2:ERG fusion transcripts in urine from prostate cancer patients correlate with a less favorable prognosis. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 575-582. doi: 10.1111/j.1600-0463.2009.02517.x
  • Salvesen, Helga Birgitte; Carter, Scott L.; Mannelqvist, Monica; Dutt, Amit; Getz, Gad; Stefansson, Ingunn Marie; Ræder, Maria Therese Barøy; Sos, Martin L.; Engelsen, Ingeborg Bøe; Trovik, Jone; Wik, Elisabeth; Greulich, Heidi; Bø, Trond Hellem; Jonassen, Inge; Thomas, Roman K.; Zander, Tim; Garraway, Levi A.; Øyan, Anne Margrete; Sellers, William R.; Kalland, Karl-Henning; Meyerson, Matthew; Akslen, Lars A.; Beroukhim, Rameen. 2009. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 4834-4839. doi: 10.1073/pnas.0806514106
  • Wik, Elisabeth; Trovik, Jone; Iversen, Ole-Erik; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Vestrheim, LC; Haugland, Hans K.; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting. American Journal of Obstetrics and Gynecology. 201: 603-607. doi: 10.1016/j.ajog.2009.07.029
  • Akslen, Lars A.; Naumov, George N. 2008. Tumor dormancy - from basic mechanisms to clinical practice. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 545-547. doi: 10.1111/j.1600-0463.2008.01209.x
  • Akslen, Lars A.; Puntervoll, Hanne Eknes; Bachmann, Ingeborg M.; Straume, Oddbjørn; Vuhahula, Edda; Kumar, Rajiv; Molven, Anders. 2008. Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma. Melanoma research. 18: 29-35.
  • Arnes, Jarle; Collett, Karin; Akslen, Lars A. 2008. Lesson of the Month - Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1. Histopathology. 52: 370-380. doi: 10.1111/j.1365-2559.2007.02957.x
  • Arnes, Jarle; Foulkes, William D.; Akslen, Lars A. 2008. Candidate stem cell marker ALDH1 expression and relationship with BRCA-mutations and basal-like differentiation in breast carcinoma. Histopathology. 53: 25-25.
  • Bachmann, Ingeborg M.; Ladstein, Rita Grude; Straume, Oddbjørn; Naumov, GN; Akslen, Lars A. 2008. Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer. 8: 362-372. doi: 10.1186/1471-2407-8-362
  • Bachmann, Ingeborg M.; Puntervoll, Hanne Eknes; Otte, Arie P.; Akslen, Lars A. 2008. Loss of BMI-1 expression is associated with clinical progress of malignant melanoma. Modern Pathology. 21: 583-590. doi: 10.1038/modpathol.2008.17
  • Borkamo, Erling Dahl; Fluge, Øystein; Mella, Olav; Akslen, Lars A.; Bruland, Ove; Dahl, Olav. 2008. Hyperthermia improves the antitumour effect of metronomic cyclophosphamide in a rat transplantable brain tumour. Radiotherapy and Oncology. 86: 435-442. doi: 10.1016/j.radonc.2008.01.022
  • Dutt, Amit; Salvesen, Helga; Chent, Tzu-Hsiu; Ramos, Alex H.; Onofrio, Robert C.; Hatton, Charlie; Nicoletti, Richard; Winckler, Wendy; Grewal, Rupinder; Hanna, Megan; Wyhs, Nicolas; Ziaugra, Liuda; Richter, Daniel J.; Trovik, Jone; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Fennell, Tim; Cibulskis, Kristian; Zody, Michael C.; Akslen, Lars A.; Gabriel, Stacey; Wong, Kwok-Kin; Sellers, William R.; Meyerson, Matthew; Greulich, Heidi. 2008. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 8713-8717. doi: 10.1073/pnas.0803379105
  • Engelsen, Ingeborg Bøe; Mannelqvist, Monica; Stefansson, Ingunn Marie; Carter, Scott L.; Beroukhim, Rameen; Øyan, Anne Margrete; Otte, Ariel P.; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2008. Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma. British Journal of Cancer. 98: 1662-1669. doi: 10.1038/sj.bjc.6604360
  • Engelsen, Ingeborg Bøe; Stefansson, IM; Akslen, Lars A.; Salvesen, Helga Birgitte. 2008. GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival. American Journal of Obstetrics and Gynecology. 199: e 1-7. doi: 10.1016/j.ajog.2008.04.043
  • Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Beroukhim, Rameen; Sellers, William R.; Meyerson, Matthew; Akslen, Lars A.; Salvesen, Helga. 2008. HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas. International Journal of Oncology. 32: 307-316.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2008. Vascular proliferation by Nestin/Ki-67 is a novel predictor of the clinical progress of prostate cancer. Histopathology. 53: 276-277.
  • Helsing, Per; Nyrnoen, Dag André; Ariansen, Sarah; Steine, Solrun; Mæhle, Lovise; Aamdal, Steinar; Langmark, Frøydis; Loeb, Mitchell; Akslen, Lars A.; Molven, Anders; Andresen, Per Arild Kjølseth. 2008. Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas. Genes, Chromosomes and Cancer. 47: 175-184. doi: 10.1002/gcc.20518
  • Ke, Xisong; Qu, Yi; Goldfinger, Naomi; Rostad, Kari; Hovland, Randi; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation. PLoS ONE. 3. doi: 10.1371/journal.pone.0003368
  • Lin, Biaoyang; Utleg, Angelita G.; Gravdal, Karsten; White, James T.; Halvorsen, Ole Johan; Lu, Wei; True, Lawrence D.; Vessella, Robert; Lange, Paul H.; Nelson, Peter S.; Hood, Leroy; Kalland, Karl-Henning; Akslen, Lars A. 2008. WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence. Clinical Cancer Research. 14: 1397-1406. doi: 10.1158/1078-0432.CCR-07-1535
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2008. Expression of EGFR and c-kit is associated with the basal-like phenotype in breast carcinomas of African women. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 515-525. doi: 10.1111/j.1600-0463.2008.01024.x
  • Naumov, George N.; Folkman, Judah; Straume, Oddbjørn; Akslen, Lars A. 2008. Tumor-vascular interactions and tumor dormancy. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 569-585. doi: 10.1111/j.1600-0463.2008.01213.x
  • Naumov, George N.; Heymach, John; Akslen, Lars A. 2008. Dr. Folkman's legacy - a life of angiogenesis research. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 89-92. doi: 10.1111/j.1600-0463.2008.00123.x
  • Bachmann, Ingeborg M.; Eknes, HE; Otte, Ariel P.; Akslen, Lars A. 2007. Loss of BMI-1 expression is associated with the clinical progress of malignant melanoma. Virchows Archiv. 451: 452-452.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. A Switch from E-Cadherin to N-Cadherin Expression Indicates Epithelial to Mesenchymal Transition and Is of Strong and Independent Importance for the Progress of Prostate Cancer. Clinical Cancer Research. 13: 7003-7011. doi: 10.1158/1078-0432.CCR-07-1263
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. Epithelial to mesenchymal transition is of strong prognostic importance in prostate cancer. Virchows Archiv. 451: 344-344.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Puntervoll, Hanne Eknes; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2007. Increased expression of sim2-s protein is a novel marker of aggressive prostate cancer. Clinical Cancer Research. 13: 892-897. doi: 10.1158/1078-0432.CCR-06-1207
  • Nalwoga, H; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2007. Basal-like phenotype is frequent in invasive breast carcinoma from Ugandan Africans and is strongly associated with a high expression of EGFR/c-Kit and features of aggressive tumors. Virchows Archiv. 451: 137-137.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2007. Frequency of the basal-like phenotype in African breast cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 115: 1391-1399. doi: 10.1111/j.1600-0463.2007.00862.x
  • Naumov, George N.; Watnick, Randolph S.; Almog, Nava; Akslen, Lars A.; Folkman, Judah. 2007. Re: A model of human tumor dormancy: An angiogenic escape from the nonangiogenic phenotype - Response. Journal of the National Cancer Institute. 99: 331-332. doi: 10.1093/jnci/djk056
  • Petersen, Kjell; Øyan, Anne Margrete; Rostad, Kari; Olsen, Sue; Bø, Trond Hellem; Salvesen, Helga; Gjertsen, Bjørn Tore; Bruserud, Øystein; Halvorsen, Ole Johan; Akslen, Lars A.; Steen, Vidar Martin; Jonassen, Inge; Kalland, Karl-Henning. 2007. Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization. Analytical Biochemistry. 366: 46-58. doi: 10.1016/j.ab.2007.03.013
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2007. ERG upregulation and related ETS transcription factors in prostate cancer. International Journal of Oncology. 30: 19-32.
  • Tischkowitz, Marc; Brunet, Jean-Sébastien; Bégin, Louis R.; Huntsman, David G.; Cheang, Maggie C.U.; Akslen, Lars A.; Nielsen, Torsten O.; Foulkes, William D. 2007. Use of immunohistochemical markers can refine prognosis in triple negative breast cancer. BMC Cancer. 7. 11 pages. doi: 10.1186/1471-2407-7-134
  • Bachmann, Ingeborg Margrethe; Halvorsen, Ole Johan; Collett, Karin; Stefansson, Ingunn Marie; Straume, Oddbjørn; Haukaas, Svein Andreas; Salvesen, Helga; Otte, Arie P.; Akslen, Lars A. 2006. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. Journal of Clinical Oncology. 24: 268-273. doi: 10.1200/JCO.2005.01.5180
  • Collett, Karin; Eide, Geir Egil; Arnes, Jarle; Stefansson, Ingunn Marie; Eide, Johan; Braaten, Audun; Aas, Turid; Otte, Ariel P.; Akslen, Lars A. 2006. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clinical Cancer Research. 12: 1168-1174. doi: 10.1158/1078-0432.CCR-05-1533
  • Engeland, Anders; Tretli, Steinar; Akslen, Lars Andreas; Bjørge, Tone. 2006. Body size and thyroid cancer in two million Norwegian men and women. British Journal of Cancer. 95: 366-370. doi: 10.1038/sj.bjc.6603249
  • Engelsen, Ingeborg; Stefansson, Ingunn Marie; Akslen, Lars A.; Salvesen, Helga. 2006. Pathologic expression of p53 or p16 in preoperative curettage specimens identifies high-risk endometrial carcinomas. American Journal of Obstetrics and Gynecology. 195: 979-986.
  • Fluge, Øystein; Bruland, Ove; Akslen, Lars A.; Lillehaug, Johan; Varhaug, Jan Erik. 2006. Gene expression in poorly differentiated papillary thyroid carcinomas. Thyroid. 16: 161-175.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2006. Expression of bFGF/FGFR-1 and vascular proliferation related to clinicopathologic features and tumor progress in localized prostate cancer. Virchows Archiv. 448: 68-74.
  • Haukaas, Svein Andreas; Halvorsen, Ole Johan; Dæhlin, Lars; Høstmark, Jens; Akslen, Lars A. 2006. Is preoperative serum prostate-specific antigen level significantly related to clinical recurrence after radical 14 retropubic prostatectomy for localized prostate cancer? BJU International. 97: 51-55. doi: 10.1111/j.1464-410X.2006.05886
  • Kalland, Karl-Henning; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2006. Global gene expression analysis of transcription factors in prostate cancer and cell lines. International Journal of Molecular Medicine. 18: S27. Published 2006-10-14.
  • Naumov, George N.; Akslen, Lars A.; Folkman, Judah. 2006. Role of angiogenesis in human tumor dormancy - Animal models of the angiogenic switch. Cell Cycle. 5: 1779-1787.
  • Naumov, George N.; Bender, Elise; Zurakowski, David; Kang, Soo-Young; Sampson, David; Flynn, Evelyn; Watnick, Randolph S.; Straume, Oddbjørn; Akslen, Lars A.; Folkman, Judah; Almog, Nava. 2006. A model of human tumor dormancy: An angiogenic switch from the nonangiogenic phenotype. Journal of the National Cancer Institute. 98: 316-325. doi: 10.1093/jnci/djj068
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Ulvestad, Elling; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2006. ERG upregulation in relation to other transcription factors in prostate cancer. NBS-nytt. 1: 72.
  • Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2006. Vascular proliferation is important for clinical progress of endometrial cancer. Cancer Research. 66: 3303-3309.
  • Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2006. Loss of p63 and cytokeratin 5/6 expression is associated with more aggressive tumors in endometrial carcinoma patients. International Journal of Cancer. 118: 1227-1233. doi: 10.1002/ijc.21415
  • Sørlie, Therese; Perou, Charles M.; Fan, Cheng; Geisler, Stephanie; Aas, Turid; Nobel, Andrew; Anker, Gun; Akslen, Lars A.; Botstein, David; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 2006. Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer. Molecular Cancer Therapeutics. 5: 2914-2918. doi: 10.1158/1535-7163.MCT-06-0126
  • Akslen, Lars A.; Angelini, Sabrina; Straume, Oddbjørn; Molven, Anders; Bachmann, Ingeborg; Hemminki, Kari; Kumar, Rajiv. 2005. BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival. Journal of Investigative Dermatology. 125: 312-317.
  • Bachmann, Ingeborg; Straume, Oddbjørn; Puntervoll, Hanne Eknes; Kalvenes, May Britt; Akslen, Lars A. 2005. Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clinical Cancer Research. 11: 8606-8614. doi: 10.1158/1078-0432.CCR-05-0011
  • Collett, Karin; Stefansson, Ingunn Marie; Eide, Johan; Braaten, Audun; Wang, Hege; Eide, Geir Egil; Thoresen, Steinar Østerbø; Thoresen, Steinar; Foulkes, William D.; Akslen, Lars A. 2005. A basal epithelial phenotype is more frequent in interval breast cancers compared with screen detected tumors. Cancer Epidemiology, Biomarkers and Prevention. 14: 1108-1112.
  • Gjengstø, Peder; Paus, Elisabeth; Halvorsen, OJ; Eide, J; Akslen, LA; Wentzel-Larsen, T; Hoisaeter, PA. 2005. Predictors of prostate cancer evaluated by receiver operating characteristics partial area index: a prospective institutional study. Journal of Urology. 173: 425-428.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2005. Single-minded 2 homolog gene is overexpressed in prostate cancer. Virchows Archiv. 447: 432-432.
  • Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Rostad, Kari; Haukaas, Svein Andreas; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Stordrange, Laila; Lin, Biaoyang; Jonassen, Inge; Hood, Leroy; Akslen, Lars A.; Kalland, Karl-Henning. 2005. Gene expression profiles in prostate cancer: Association with patient subgroups and tumour differentiation. International Journal of Oncology. 26: 329-336.
  • Kalland, Karl-Henning; Halvorsen, Ole Johan; Rostad, Kari; Mannelqvist, Monica; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2005. Overexpression of ERG and SIM2 transcription factors in prostate cancer. International Journal of Molecular Medicine. 16: S76-S76.
  • Molven, Anders; Grimstvedt, Magne B.; Steine, Solrun; Harland, Mark; Avril, Marie-Françoise; Hayward, Nicholas K.; Akslen, Lars A. 2005. A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation. Genes, Chromosomes and Cancer. 44: 10-18. doi: 10.1002/gcc.20202
  • Salvesen, Helga; Kumar, Rajiv; Stefansson, Ingunn Marie; Angelini, Sabrina; MacDonald, Nicola; Smeds, Johanna; Jacobs, Ian J.; Hemminki, Kari; Das, Soma; Akslen, Lars A. 2005. Low frequency of BRAF and CDKN2A mutations in endometrial cancer. International Journal of Cancer. 115: 930-934. doi: 10.1002/ijc.20702
  • Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Skaane, P; Urdal, Petter; Berghagen, Hege; Jensen, Maianne; Kristiansen, Lena; Moen, Cecilie; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Sauer, Toril; Akslen, Lars A; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Lönneborg, Anders. 2005. Early detection of brest cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. 7: R634-R644. doi: 10.1186/bcr1203
  • Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Urdal, Petter; Berghagen, Hege; Jensen, Marianne; Moen, Cecilie; Kristiansen, Lena; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Akslen, Lars A.; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Lönneborg, Anders. 2005. Early detection of breast cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. 7: 634-644. doi: 10.1186/bcr1203
Book sections
  • Akslen, Lars A. 2017. Tissue-Based Biomarkers of Tumor-Vascular Interactions. 3, pages 55-76. In:
    • Akslen, Lars A.; Watnick, Randolph S. 2017. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Springer. 534 pages. ISBN: 978-3-319-39145-8.
  • Akslen, Lars A.; Watnick, Randolph S. 2017. Preface. Preface. In:
    • Akslen, Lars A.; Watnick, Randolph S. 2017. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Springer. 534 pages. ISBN: 978-3-319-39145-8.
  • Wik, Elisabeth; Akslen, Lars A. 2017. Gene expression signatures of the tumor microenvironment: relation to tumor progress in breast cancer. 16, pages 379-407. In:
    • Akslen, Lars A.; Watnick, Randolph S. 2017. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Springer. 534 pages. ISBN: 978-3-319-39145-8.
  • Akslen, Lars A. 2008. Pathology of Breast Tumors in Hereditary Breast Cancer. Section 5: Cliical Management of Heredidtary Breast Cancer, Chapter 18, pages 319-332. In:
    • Isaacs, Claudine; Rebbeck, Timothy R. 2008. Hereditary Breast Cancer. 400 pages. ISBN: 978-0-8493-9022-7.

More information in national current research information system (CRIStin)