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Nello Blaser

Associate Professor

My research interests are focused on topological methods in statistics and machine learning. Topological data analysis refers to the analysis of data shape. My research spans from encoding of data into filtered simplicial complexes (topological representation), approximations of filtered simplicial complexes (sparsification), validation measures of unsupervised persistent homology, data benchmarks, efficient vector representations of persistent homology for supervised machine learning and applications of topological methods in biology and geophysics.

Academic article
  • Show author(s) (2023). Kernelization for Finding Lineal Topologies (Depth-First Spanning Trees) with Many or Few Leaves. Lecture Notes in Computer Science (LNCS). 392-405.
  • Show author(s) (2023). Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod. Frontiers in Physiology. 17 pages.
  • Show author(s) (2023). Early response evaluation by single cell signaling profiling in acute myeloid leukemia. Nature Communications.
  • Show author(s) (2022). Relative Persistent Homology. Discrete & Computational Geometry. 949-963.
  • Show author(s) (2022). GUBS: Graph-based unsupervised brain segmentation in MRI images. Journal of Imaging. 1-17.
  • Show author(s) (2022). Early response evaluation by single cell signaling profiling in acute myeloid leukemia. Research Square.
  • Show author(s) (2022). ETH-Tight Algorithms for Finding Surfaces in Simplicial Complexes of Bounded Treewidth. Leibniz International Proceedings in Informatics. 1-16.
  • Show author(s) (2021). Semi-conditional variational auto-encoder for flow reconstruction and uncertainty quantification from limited observations. Physics of Fluids. 23 pages.
  • Show author(s) (2020). Wearing-off at the end of natalizumab dosing intervals is associated with low receptor occupancy. Neurology: Neuroimmunology and neuroinflammation. 1-8.
  • Show author(s) (2020). Relative Persistent Homology. Leibniz International Proceedings in Informatics. 1-10.
  • Show author(s) (2020). Optimal sensors placement for detecting CO2 discharges from unknown locations on the seafloor. International Journal of Greenhouse Gas Control.
  • Show author(s) (2020). Binary time series classification with Bayesian convolutional neural networks when monitoring for marine gas discharges . Algorithms. 24 pages.
  • Show author(s) (2019). Sparse Nerves in Practice. Lecture Notes in Computer Science (LNCS). 272-284.
  • Show author(s) (2019). Sparse Dowker nerves. Journal of Applied and Computational Topology.
  • Show author(s) (2019). Optimization of receptor occupancy assays in mass cytometry: Standardization across channels with QSC beads. Cytometry Part A. 314-222.
  • Show author(s) (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. Marine Environmental Research. 39-51.
  • Show author(s) (2019). Candidate markers for stratification and classification in rheumatoid arthritis. Frontiers in Immunology. 1-8.
  • Show author(s) (2018). The effect of monitoring viral load and tracing patients lost to follow-up on the course of the HIV epidemic in Malawi: A mathematical model. Open Forum Infectious Diseases. 1-9.
  • Show author(s) (2018). Sparse Filtered Nerves . arXiv.org.
  • Show author(s) (2018). RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. Aquatic Toxicology. 174-186.
  • Show author(s) (2018). Evaluating model reduction under parameter uncertainty. BMC Systems Biology. 1-10.
  • Show author(s) (2018). Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. Chemosphere. 328-339.
  • Show author(s) (2018). Divisive Cover. Mathematics in Computer Science. 1-9.
  • Show author(s) (2017). Impact of screening and antiretroviral therapy on anal cancer incidence in HIV-positive MSM. AIDS (London). 1859-1866.
  • Show author(s) (2017). Filtered covers. arXiv.org.
Lecture
  • Show author(s) (2019). Machine Learning in Mathematical Modeling.
  • Show author(s) (2019). A draft metabolic reconstruction of Atlantic cod (Gadus morhua) liver: how to and what for?
  • Show author(s) (2017). Clinical trials for biomarker detection and evaluation - opportunities, benefits and challenges - The biostatistician’s view.
Academic lecture
  • Show author(s) (2021). Revealing Multimodality in Ensemble Weather Prediction.
  • Show author(s) (2020). Relative Persistent Homology.
  • Show author(s) (2020). A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua).
  • Show author(s) (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • Show author(s) (2019). Toxicogenomic responses in Atlantic cod (Gadus morhua) after treatment with selected environmental contaminants in vivo and ex vivo.
  • Show author(s) (2019). The chemical defensome of Atlantic cod (Gadus morhua).
  • Show author(s) (2019). Sparse Nerves in Practice.
  • Show author(s) (2019). EFFECTS OF SELECTED ENVIRONMENTAL ESTROGENS ON EXPRESSION OF FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY GENES IN THE LIVER OF ATLANTIC COD (GADUS MORHUA) IN VIVO AND EX VIVO.
  • Show author(s) (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • Show author(s) (2019). Bayesian convolutional neural networks as a tool to detect discharges of pollutants to marine waters through time series classification.
  • Show author(s) (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA).
  • Show author(s) (2018). The need for proper environmental statistics to design adequate monitoring for offshore geological storage of CO2 projects.
  • Show author(s) (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
  • Show author(s) (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
  • Show author(s) (2018). Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human.
  • Show author(s) (2018). Modelling the chemical defensome network - a dynamic visualisation of the involved genes and pathways in two fish species and humans .
  • Show author(s) (2018). Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans.
  • Show author(s) (2018). Machine Learning in CO2 leak detection.
  • Show author(s) (2018). Discovering pathway perturbations with topological edge set enrichment analysis (TESEA).
  • Show author(s) (2018). Combining Models and Machine Learning Techniques to Design Leak Detection Monitoring .
  • Show author(s) (2018). Adverse health effects related to chemical exposure in Atlantic cod (Gadus morhua) from Norwegian fjords.
  • Show author(s) (2017). Topological Data Analysis in Epidemiology.
  • Show author(s) (2017). PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT.
  • Show author(s) (2017). Model reduction under parameter uncertainty.
  • Show author(s) (2017). Model reduction under parameter uncertainty.
  • Show author(s) (2017). Divisive cover classification.
  • Show author(s) (2017). An attempt at using topology for classification.
  • Show author(s) (2017). Adverse effects in Atlantic cod (Gadus morhua) due to environmental exposure to pollutant mixtures from the Oslofjord, Norway.
Short communication
  • Show author(s) (2021). Wearing-off symptoms during standard and extended natalizumab dosing intervals: Experiences from the COVID-19 pandemic. Journal of the Neurological Sciences. 1-3.
Masters thesis
  • Show author(s) (2023). Learning Acquisition Functions for Cost-aware Bayesian Optimization.
Academic chapter/article/Conference paper
  • Show author(s) (2021). Revealing Multimodality in Ensemble Weather Prediction.
  • Show author(s) (2008). Sparse Nerves in Practice. 13 pages.
Poster
  • Show author(s) (2020). Reconstruction of Currents Based on Sparse Observations with Deep Learning.
  • Show author(s) (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • Show author(s) (2019). THE CHEMICAL DEFENSOME OF ATLANTIC COD (GADUS MORHUA): HOW DOES IT DIFFER FROM DEFENSOME NETWORKS IN OTHER TELEOST SPECIES?
  • Show author(s) (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) .
  • Show author(s) (2019). A draft metabolic reconstruction of Atlantic cod (Gadus morhua) liver .
  • Show author(s) (2018). Persistent homology and network analyses reveal key gene interactions affected by environmental pollutants in Atlantic cod.
  • Show author(s) (2018). Mathematical methods for detection and localization of CO2 leaks.
  • Show author(s) (2018). MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human.
  • Show author(s) (2018). Diagnosing rheumatoid arthritis with mass cytometry using topological data analysis.
  • Show author(s) (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua).
  • Show author(s) (2017). dCod 1.0 decoding the systems toxicology of Atlantic cod.
  • Show author(s) (2017). Model reduction under parameter uncertainty.
  • Show author(s) (2017). Assessment of Topological Data Analysis and Machine Learning Technologies as Tools for Seep Detection.
Errata
  • Show author(s) (2023). Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia (Nature Communications, (2023), 14, 1, (115), 10.1038/s41467-022-35624-4). Nature Communications.
Article in business/trade/industry journal
  • Show author(s) (2020). Semi Conditional Variational Auto-Encoder for Flow Reconstruction and Uncertainty Quantification from Limited Observations. arXiv.

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