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Nicolas Delaleu

Researcher , Group Leader; ‘Omics’ Data Analysis and Visualization Group
  • E-mailNicolas.Delaleu@uib.no
  • Phone+47 55 97 46 64
  • Visitor Address
    Department of Clinical Science, University of Bergen
    5021 Bergen
    Room 
    Laboratory Building, 5th floor, #5426
  • Postal Address
    Postboks 7803
    5020 Bergen
Journal articles
  • Benedyk, Małgorzata; Mydel, Piotr Mateusz; Delaleu, Nicolas; Płaza, Karolina; Gawron, Katarzyna; Milewska, Aleksandra; Maresz, Katarzyna; Kozieł, Joanna; Pyrć, Krzysztof; Potempa, Jan. 2016. Gingipains: critical factors in the development of aspiration pneumonia caused by porphyromonas gingivalis. Journal of Innate Immunity. 8: 185-198. doi: 10.1159/000441724
  • Bergum, Brith; Koro, Catalin; Delaleu, Nicolas; Solheim, Magne; Hellvard, Annelie; Binder, Veronika; Jonsson, Roland; Valim, Valeria; Hammenfors, Daniel; Jonsson, Malin V; Mydel, Piotr Mateusz. 2016. Antibodies against carbamylated proteins are present in primary Sjögren's syndrome and are associated with disease severity. Annals of the Rheumatic Diseases. 75: 1494-1500. doi: 10.1136/annrheumdis-2015-207751
  • Delaleu, Nicolas; Mydel, Piotr Mateusz; Brun, Johan G; Jonsson, Malin V; Alimonti, Andrea; Jonsson, Roland. 2016. Sjögren's syndrome patients with ectopic germinal centers present with a distinct salivary proteome. Rheumatology. 55: 1127-1137. doi: 10.1093/rheumatology/kew013
  • Hellvard, Annelie; Zeitlmann, Lutz; Heiser, Ulrich; Kehlen, Astrid; Niestroj, André; Demuth, Hans-Ulrich; Koziel, Joanna; Delaleu, Nicolas; Potempa, Jan; Mydel, Piotr Mateusz. 2016. Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis. Scientific Reports. 6:32441: 1-11. doi: 10.1038/srep31441
  • Koro, Catalin; Hellvard, Annelie; Delaleu, Nicolas; Binder, Veronika; Scavenius, Carsten; Bergum, Brith; Gówczyk, Izabela; Roberts, Helen M.; Chapple, Iain L.C.; Grant, Melissa M.; Rapala-Kozik, Maria; Klaga, Kinga; Enghild, Jan J.; Potempa, Jan; Mydel, Piotr Mateusz. 2016. Carbamylated LL-37 as a modulator of the immune response. Innate Immunity. 22: 218-229. doi: 10.1177/1753425916631404
  • Revandkar, Ajinkya; Perciato, Maria Luna; Toso, Alberto; Alajati, Abdullah; Chen, Jingjing; Gerber, Hermeto; Dimitrov, Mitko; Rinaldi, Andrea; Delaleu, Nicolas; Pasquini, Emiliano; D'Antuono, Rocco; Pinton, Sandra; Losa, Marco; Gnetti, Letizia; Arribas, Alberto; Fraering, Patrick; Bertoni, Francesco; Nepveu, Alain; Alimonti, Andrea. 2016. Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Nature Communications. 7:13719: 1-12. doi: 10.1038/ncomms13719
  • Delaleu, Nicolas; Mydel, Piotr Mateusz; Kwee, Ivo; Brun, Johan G; Jonsson, Malin V; Jonsson, Roland. 2015. High fidelity between saliva proteomics and the biologic state of salivary glands defines biomarker signatures for primary Sjögren's syndrome. Arthritis & Rheumatology. 67: 1084-1095. doi: 10.1002/art.39015
  • Kalathur, Madhuri; Toso, Alberto; Chen, Jingjing; Revandkar, Ajinkya; Danzer-Baltzer, Claudia; Guccini, Ilaria; Alajati, Abdullah; Sarti, Manuela; Pinton, Sandra; Brambilla, Lara; Di Mitri, Diletta; Carbone, Giuseppina; García-Escudero, Ramón; Padova, Alessandro; Magnoni, Letizia; Tarditi, Alessia; Maccari, Laura; Malusa, Federico; Kalathur, Ravi Kiran Reddy; Pinna, Lorenzo A.; Cozza, Giorgio; Ruzzene, Maria; Delaleu, Nicolas; Catapano, Carlo V.; Frew, Ian J.; Alimonti, Andrea. 2015. A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours. Nature Communications. 6:7227. doi: 10.1038/ncomms8227
  • Delaleu, Nicolas; Nguyen, Cuong Q; Tekle, Kidane M; Jonsson, Roland; Peck, Ammon B. 2013. Transcriptional landscapes of emerging autoimmunity: transient aberrations in the targeted tissue's extracellular milieu precede immune responses in Sjogren's syndrome. Arthritis Research & Therapy. 15. doi: 10.1186/ar4362
  • Ledahl, Suzanne; Vogelsang, Petra; Jonsson, Roland; Lycke, Nils; Delaleu, Nicolas. 2013. Modulation of experimental Sjögren's Syndrome and diabetes via mucosal vaccination with fusion proteins derived from cholera-toxin and heat shock protein 60 kDa. Scandinavian Journal of Immunology. 77: 321-321.
  • Ledahl, Suzanne Lovise; Vogelsang, Petra; Jonsson, Roland; Lycke, Nils Y.; Delaleu, Nicolas. 2012. Modulation of experimental Sjögren's syndrome and diabetes via mucosal vaccination with fusion proteins derived from cholera-toxin and heat shock protein 60 kDa. Immunology. 137: 766-766. doi: 10.1111/imm.12002
  • Delaleu, Nicolas; Nquyen, Cuong; Peck, Ammon B.; Jonsson, Roland. 2011. Sjögren's syndrome: studying the disease in mice. Arthritis Research & Therapy. 13. 16 pages. doi: 10.1186/ar3313
  • Jonsson, Malin V; Reksten, Tove Ragna; Delaleu, Nicolas; Cuida Marthinussen, Ileana Mihaela. 2011. Diagnostikk av munntørrhet og bruk av saliva somdiagnostisk verktøy. Den norske tannlegeforenings tidende. 121: 908-913.
  • Nordmark, Gunnel; Kristjansdottir, Gudlaug; Theander, Elke; Appel, Silke; Eriksson, Per; Vasaitis, Lillian; Kvarnström, Marika; Delaleu, Nicolas; Lundmark, Per; Lundmark, Anders; Sjöwall, Christopher; Brun, Johan G; Jonsson, Malin V; Harboe, Erna; Gøransson, Lasse G; Johnsen, Svein Joar Auglæn; Söderkvist, Peter; Eloranta, Maija-Leena; Alm, Gunnar V.; Baecklund, Eva; Wahren-Herlenius, Marie; Omdal, Roald; Rönnblom, Lars; Jonsson, Roland; Syvänen, Ann-Christine. 2011. Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome. Genes and Immunity. 12: 100-109. doi: 10.1038/gene.2010.44
  • Berggreen, Ellen; Nyløkken, Krister; Delaleu, Nicolas; Hajdaragic-Ibricevic, Hamieta; Jonsson, Malin V. 2009. Impaired vascular responses to parasympathetic nerve stimulation in the submandibular gland in NOD mice. Arthritis Research & Therapy. 11. doi: 10.1186/ar2609
  • Delaleu, Nicolas; Peck, AB. 2009. Autoimmunity: limited progress for the patient, despite decades of research. Scandinavian Journal of Immunology. 70: 411-414. doi: 10.1111/j.1365-3083.2009.02318.x
  • Delaleu, Nicolas; Immervoll, Heike; Cornelius, Janet; Jonsson, Roland. 2008. Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations. Arthritis Research & Therapy. 10. 14 pages. doi: 10.1186/ar2375
  • Delaleu, Nicolas; Jonsson, Malin V; Appel, Silke; Jonsson, Roland. 2008. New Concepts in the Pathogenesis of Sjogren's Syndrome. Rheumatic Disease Clinics of North America. 34: 833-+. doi: 10.1016/j.rdc.2008.08.004
  • Delaleu, Nicolas; Jonsson, Roland. 2008. Altered fractalkine cleavage results in an organ-specific 17 kDa fractalkine fragment in salivary glands of NOD mice. Arthritis Research & Therapy. 10. 2 pages. doi: 10.1186/ar2458
  • Delaleu, Nicolas; Madureira, Ana Carina; Immervoll, Heike; Jonsson, Roland. 2008. Inhibition of experimental Sjögren's syndrome through immunization with heat-shock protein 60kDa and its peptide aa437-460. Arthritis and Rheumatism. 58: S795-S795.
  • Delaleu, Nicolas; Madureira, Ana Carina; Immervoll, Heike; Jonsson, Roland. 2008. Inhibition of experimental Sjögren's syndrome through immunization with Hsp60 and its peptide amino acids 437-460. Arthritis and Rheumatism. 58: 2318-2328. doi: 10.1002/art.23656
  • Jonsson, Malin V; Delaleu, Nicolas; Jonsson, Roland. 2007. Animal models of Sjögren's syndrome. Clinical reviews in allergy and immunology. 32: 215-224. doi: 10.1007/s12016-007-8012-7
  • Berggreen, Ellen; Nyløkken, Krister; Delaleu, Nicolas; Jonsson, Malin V; Hajdaragic-Ibricevic, Hamieta. 2006. Impaired vascular responses to parasympathetic stimulation in the submandibular gland in NOD mice. Arthritis and Rheumatism. 54: S709-S709.
  • Jonsson, Malin V; Delaleu, Nicolas; Brokstad, Karl Albert; Berggreen, Ellen; Skarstein, Kathrine. 2006. Impaired salivary gland function in nod mice - Association with changes in cytokine profile but not with salivary gland histopathology. Arthritis and Rheumatism. 54: S707-S707.
  • Jonsson, Malin V; Delaleu, Nicolas; Brokstad, Karl Albert; Berggreen, Ellen; Skarstein, Kathrine. 2006. Impaired salivary gland function in NOD mice - Association with changes in cytokine profile but not with histopathologic changes in the salivary gland. Arthritis and Rheumatism. 54: 2300-2305. doi: 10.1002/art.21945
  • Delaleu, Nicolas; Jonsson, Roland; Koller, Markus M. 2005. Sjögren's syndrome. European Journal of Oral Sciences. 113: 101-113.
  • Szodoray, Peter; Alex, Phillip; Jonsson, Malin V; Knowlton, Nicholas; Dozmorov, Igor; Nakken, Britt; Delaleu, Nicolas; Jonsson, Roland; Centola, Mike. 2005. Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF. Clinical Immunology. 117: 168-176. doi: 10.1016/j.clim.2005.06.016
  • Delaleu, Nicolas; Jonsson, Malin V; Jonsson, Roland. 2004. Disease mechanisms of Sjögren's syndrome. Drug Discovery Today. 1: 329-336.
Reports and theses
  • Delaleu, Nicolas. 2008. The Autonomy of Different Aspects of Sjögren's Syndrome and their Treatment in an Experimental Model. 100 pages.
Book sections
  • Delaleu, Nicolas; Manoussakis, Manelaos N; Moutsopoulos, Haralampos M.; Jonsson, Roland. 2011. Etiology and Pathogenesis of Sjögren's Syndrome with Special Emphasis on the Salivary Glands. 15, pages 243-267. In:
    • Fox, Robert I; Fox, Carla M. 2011. Sjögren's Syndrome Practical Guidelines to Diagnosis and Therapy. Springer. 505 pages. ISBN: 978-1-60327-956-7.
  • Jonsson, Malin V; Delaleu, Nicolas; Cuida Marthinussen, Ileana Mihaela; Jonsson, Roland. 2011. Oral and Dental Manifestations of Sjögren's Syndrome: Current Approaches to Diagnostics and Therapy. 15, pages 221-242. In:
    • Fox, Robert I; Fox, Carla M. 2011. Sjögren's Syndrome Practical Guidelines to Diagnosis and Therapy. Springer. 505 pages. ISBN: 978-1-60327-956-7.

More information in national current research information system (CRIStin)

Curriculum Vitae:

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