Night shift work is associated with sleep problems and multiple other negative health effects. Prolonged wakefulness induces deficits in brain functions, which affects alertness, performance and mood. My PhD-project is a translational project and involves simulating night-shift work in both rats and humans. I aim to investigate how night-shift work affects waking function and cognitive performance during work, and subsequent sleep. I will also investigate how different light interventions during simulated night-shifts will affect the brains' processing capasity and how it may impact daytime sleep.
- 2016. A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. Journal of Biological Rhythms. 32: 48-63. doi: 10.1177/0748730416675460
- 2016. Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shiftwork: A rat model. Nutrients. 8:712: 1-13. doi: 10.3390/nu8110712
A rodent model of night-shift work induces short-term and enduring sleep and electroencephalographic disturbances. Grønli J, Meerlo P, Pedersen TT, Pallesen S, Skrede S, Marti AR, Wisor JP, Murison R, Henriksen TEG, Rempe MJ, Mrdalj J. J Biol Rhythm, 2017 Feb;32(1):48-63. doi: 10.1177/0748730416675460.
Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shift work. A rat model. Marti AR, Meerlo P, Grønli J, van Hasselt SJ, Mrdalj J, Pallesen S, Pedersen TT, Henriksen TEG, Skrede S.Nutrients, 2016 Nov 8;8(11). pii: E712