Selected Publications

Main content

Original Research Articles

Eriksen, M. S., Nikolaienko, O., Hallin, E. I., Grødem, S., Bustad, H. J., Flydal, M. I., O’Connell, R., Hosokawa, T., Lascu, D., Akerkar, S., Cuéllar, J. Chambers, J.J., Muruganandam, G., Loris, R., Kanhema, T., Hayashi, Y., Stratton, M.M., Valpuesta, J.M., Kursula P., Martinez, A., and Bramham, C. R. (2019). Molecular determinants of Arc oligomerization and formation of virus-like capsids. BioRxiv, 667956. https://doi.org/10.1101/667956.
Berentsen B, Patil S, Wibrand K, Goff KM, Pajak M, Simpson IT, and Bramham CR. (2019) microRNA-34a acutely regulates synaptic efficacy in the adult dentate gyrus in vivo. Molecular Neurobiology, Doi: 10.1007/s12035-019-01816-1
Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Grødem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P. Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities.
J Neurochem. 2018 Jul 20. doi: 10.1111/jnc.14556. [Epub ahead of print]
PMID:30028513
Nikolaienko O, Eriksen MS, Patil S, Bito H, Bramham CR (2017) Stimulus-evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization. Neuroscience 360:68–80. doi: 10.1016/j.neuroscience.2017.07.026.
Myrum, C., Soulé, J., Bittins, M., Cavagnini, K., Eriksen, M.S., Goff, K., Ziemek, S., Patil, S., Szum, A., Nair, R.R. and Bramham, C.R. (2017) Arc interacts with the integral ER protein, calnexin. Frontiers Cell Neurosci. doi.org/10.3389/fncel.2017.00294.
Myrum, C., Nikolaienko, O. Bramham, C.R. Haavik, J., Zayats, T. Implication of the APP gene in intellectual abilities. (2017) J Alz Dis. 59(2):723-735. doi: 10.3233/JAD-170049.
Gozdz, A., Nikolaienko, O., Urbanska, M., Cymerman, I.A., Sitkiewicz, E., Dadlez, M., Bramham. C.R., and Jaworski, J (2017) GSK3α and GSK3β phosphorylate Arc and regulate its degradation. Front Mol Neurosci. doi: 10.3389/fnmol.2017.00192
Marti, A.R., Patil., S., Mrdalj, J., Meerlo, P., Skrede, S., Pallesen, S., Pedersen, T.T., Bramham, C.R., and Grønli, J. (2017) No escaping the rat race: Simulated night shift work alters the time-of-day variation in BMAL1 translational activity in the prefrontal cortex. Front Neural Circuits, 11:70. doi: 10.3389/fncir.2017.00070
Nair RR, Patil S, Tiron A, Kanhema TW, Panja D, Schiro L, Parobczak K, Wilczynski G, Bramham CR (2017) Dynamic Arc SUMOylation and selective interaction with F-actin binding protein drebrin A in LTP consolidation in vivo. Frontiers in Synaptic Neuroscience (2017). doi:10.3389/fnsyn.2017.00008.
J.L.V. Maag, D.C. Kaczorowski, D. Panja, T.J. Peters, C.R. Bramham, K. Wibrand, M.E. Dinger, Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo, BMC Genomics. 18 (2017) 250. doi:10.1186/s12864-017-3621-x
Kuipers, S., Trentani, A., Tiron, A, Mao, X., Kuhl, D., and Bramham, C.R. (2016) BDNF-induced LTP is associated with rapid Arc-dependent enhancement in adult hippocampal neurogenesis. Scientific Reports, 2016; 6: 21222
Maag, J.L.V., Panja,D., Sporild, I, Patil, S., Kaczorowski, D.C., *Bramham, C.R., *Dinger, M., and *Wibrand, K. (2015) Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity. Frontiers in Neuroscience. 2015 Oct 1;9:351
Myrum C, Giddaluru S, Jacobsen K, Espeseth T, Nyberg L, Lundervold A J, Haavik J, Nilsson L, Reinvang I, Steen V M, Johansson S, Wibrand K, *Le Hellard S, and *Bramham C R. (2015) Common variants in the ARC gene are not associated with cognitive abilities. Brain and Behavior, doi: 10.1002/brb3.376.
Myrum,C., Baumann, A., Bustad, H.J., Flydal, M.I., Mariaule,V., Alvira, S., Cuéllar, J., Soulé, J., Valpuesta J.M., Márquez, J.A., Martinez, A., and Bramham,C.R. (2015) Arc is a flexible modular protein capable of reversible self-oligomerization. Biochem J. 2015 May 15;468(1):145-58
Panja, D., Kenney, J.W., D’Andrea, L., Zalfa, F., Vedeler, A., Wibrand, K., Fukunaga, R., Bagni, C., Proud, C.G., and Bramham, C.R. (2014). Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK. Cell Rep. 9, 1430–1445.
Pai, B., Siripornmongcolchai, T., Berentsen, B., Pakzad, A., Vieuille, C., Pallesen, S., Pajak, M., Simpson, T.I., Armstrong, J.D., Wibrand, K., and Bramham, C.R. (2014). NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo. Front. Cell. Neurosci. 7, 1–15.
Wibrand, K., Pai, B., Siripornmongcolchai, T, Bittins, M., Berentsen, B., Ofte, M.L, Weigel, A., Skaftnesmo, K.O., and Bramham C.R. (2012) MicroRNA regulation of the synaptic plasticity related gene Arc. PLoS ONE 7(7): e41688.
Soule J, Alme MN, Myrum C, Schubert M, Kanhema T, Bramham CR (2012) Balancing Arc synthesis, mRNA decay, and proteasomal degradation: maximal protein expression triggered by REM sleep-like bursts of muscarinic cholinergic receptor stimulation. J Biological Chemistry, 287(26): 22354-66.
Wibrand, K., Panja, D., Tiron, A., Ofte, M.L., Skaftnesmo, K. Sohn-Lee, C., Pena, J., Tuschl, T. and Bramham, C.R. (2010) Differential regulation of mature and precursor microRNA expression by NMDAR and metabotropic glutamate receptor expression activation during LTP in the dentate gyrus in vivo. Eur J Neurosci 31: 636-645.