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PROBE Publications

Publications by researchers at PROBE or where PROBE contributed significantly to the analysis of the data (marked with *).

2017 (12)

Perez-Riverol Y, Ternent T, Koch M, Barsnes H, Vrousgou O, Jupp S, Vizcaíno JA: OLS Client and OLS Dialog: Open source tools to annotate public omics datasets. Proteomics. (in press)

Verheggen K, Berven FS, Martens L, Barsnes H, Vaudel M: Anatomy and evolution of database search engines, a central cog in mass spectrometry based proteomic workflows. Mass Spectrometry Reviews. (in press)

Chambers MC, Jagtap PD, Johnson JE, McGowan T, Kumar P, Onsongo G, Guerrero CR, Barsnes H, Vaudel M, Martens L, Grüning B, Cooke IR, Heydarian M, Reddy KL, Griffin TJ: An accessible proteogenomics informatics resource for cancer researchers. Cancer Research. (in press)

Kopczynski D, Barsnes H, Njølstad PR, Sickmann A, Vaudel M, Ahrends R: PeptideMapper: Efficient and Versatile Amino Acid Sequence and Tag Mapping. Bioinformatics. (in press)

Leprevost FdV, Aflitos SA, Grüning BA, Röst HL, Uszkoreit J, Barsnes H, Vaudel M, Moreno P, Gatto L, Weber J, Bai M, Jimenez RC, Sachsenberg T, Pfeufferz J, Alvarez RV, Griss J, Nesvizhskii AI, Perez-Riverol Y: BioContainers: An open-source and community-driven framework for software standardization. Bioinformatics. (in press)

Hernandez-Valladares M, Vaudel M, Selheim F, Berven F, Bruserud Ø: Proteogenomics approaches for studying cancer biology and their potential in the identification of acute myeloid leukemia biomarkers. Expert Rev Proteomics. 2017 Aug;14(8):649-663.

Johansson BB, Fjeld K, Solheim MH, Shirakawa J, Zhang E, Keindl M, Hu J, Lindqvist A, Døskeland A, Mellgren G, Flatmark T, Njølstad PR, Kulkarni RN, Wierup N, Aukrust I, Bjørkhaug L: Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation. Mol Cell Endocrinol. 2017 Jun 22; 454:146-157.

Vizcaíno JA, Mayer G, Perkins S, Barsnes H, Vaudel M, Perez-Riverol Y, Ternent T, Uszkoreit J, Eisenacher M, Fischer L, Rappsilber J, Netz E, Walzer M, Kohlbacher O, Leitner A, Chalkley RJ, Ghali F, Martínez-Bartolomé S, Deutsch EW, Jones AR: The mzIdentML data standard v1.2 - supporting advances in proteome informatics. Mol Cell Proteomics. 2017 Jul;16(7):1275-1285.

Yadetie F, Oveland E, Døskeland A, Berven F, Goksøyr A, Karlsen OA: Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. Aquat Toxicol. 2017 Jan 30;185:19-28.

Guldbrandsen A, Farag Y, Kroksveen AC, Oveland E, Lereim RR, Opsahl JA, Myhr KM, Berven FS, and Barsnes H: CSF-PR 2.0: an interactive literature guide to quantitative cerebrospinal fluid mass spectrometry data from neurodegenerative disorders. Mol Cell Proteomics. 2017 Feb;16(2):300-309.

Kopperud RK, Rygh CB, Karlsen TV, Krakstad C, Kleppe R, Høivik EA, Bakke M, Tenstad O, Selheim F, Lidén Å, Madsen L, Pavlin T, Taxt T, Kristiansen K, Curry FE, Reed RK, Døskeland SO: Increased microvascular permeability in mice lacking Epac1 (RapGef3). Acta Physiol (Oxf). 2017 Feb;219(2):441-452.

Kroksveen AC, Guldbrandsen A, Vaudel M, Lereim RR, Barsnes H, Myhr KM, Torkildsen Ø, Berven FS: In-depth cerebrospinal fluid quantitative proteome and deglycoproteome analysis; presenting a comprehensive picture of pathways and processes affected by multiple sclerosis. J Proteome Res. 2017 Jan 6;16(1):179-194.

2016 (23)

Verheggen K, Martens L, Berven FS, Barsnes H and Vaudel M: Database Search Engines: Paradigms, Challenges and Solutions. Adv Exp Med Biol. 2016;919:147-156.

Lereim RR, Oveland E, Berven FS, Vaudel M and Barsnes H: Visualization, Inspection and Interpretation of Shotgun Proteomics Identification Results. Adv Exp Med Biol. 2016;919:227-235.

Muth T, Rapp E, Berven FS, Barsnes H and Vaudel M: Tandem Mass Spectrum Sequencing: An Alternative to Database Search Engines in Shotgun Proteomics. Adv Exp Med Biol. 2016;919:217-226.

Hernandez-Valladares M, Aasebø E, Selheim F, Berven FS, Bruserud Ø: Selecting sample preparation workflows for mass spectrometry-based proteomic and phosphoproteomic analysis of patient samples with acute myeloid leukemia. Proteomes 2016, 4(3), 24.

Tvedt TH, Reikvam H, Aasebø E, Hernandez-Valladares M, Berven FS, Selheim F, Bruserud Ø: How should quality of life assessment be integrated in the evaluation of patients with acute myeloid leukemia?, Expert Review of Quality of Life in Cancer Care 2016, 1:5, 373-387.

Brenner AK, Aasebø E, Hernandez-Valladares M, Selheim F, Berven F, Bruserud Ø: Rethinking the role of osteopontin in human acute myeloid leukemia. Leuk Lymphoma. 2016 Oct 14:1-4.

Lereim RR, Oveland E, Xiao Y, Torkildsen Ø, Wergeland S, Myhr KM, Sun S and Berven FS: The Brain Proteome of the Ubiquitin Ligase Peli1 Knock-Out Mouse during Experimental Autoimmune Encephalomyelitis. J Proteomics Bioinform 2016, 9:9.

Vaudel M, Barsnes H, Ræder H, Berven FS: Using Proteomics Bioinformatics Tools and Resources in Proteogenomic Studies. Adv Exp Med Biol. 2016;926:65-75.

Yadetie F, Bjørneklett S, Garberg HK, Oveland E, Berven F, Goksøyr A, Karlsen OA: Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. BMC Genomics. 2016 Aug 5;17:554.

Aasebø E, Mjaavatten O, Vaudel M, Farag Y, Selheim F, Berven F, Bruserud Ø, Hernandez-Valladares M: Freezing effects on the acute myeloid leukemia cell proteome and phosphoproteome revealed using optimal quantitative workflows. J Proteomics. 2016 Aug 11;145:214-25.

Yılmaz Ş, Victor B, Hulstaert N, Vandermarliere E, Barsnes H, Degroeve S, Gupta S, Sticker A, Gabriël S, Dorny P, Palmblad M, Martens L.: A pipeline for differential proteomics in unsequenced species. J Proteome Res. 2016 Jun 3;15(6):1963-70.

Valladares M, Aasebø E, Mjaavatten O, Vaudel M, Bruserud Ø, Berven F, Selheim F: Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients. Hernandez. Biol Proced Online. 2016 Jun 21;18:13.

Opsahl JA, Vaudel M, Guldbrandsen A, Aasebø E, van Pesch V, Franciotta D, Myhr KM, Barsnes H, Berle M, Torkildsen Ø, Kroksveen AC, Berven FS: Label free analysis of human cerebrospinal fluid addressing various normalization strategies and revealing protein groups affected by multiple sclerosis. Proteomics. 2016 Apr;16(7):1154-65.

Verheggen K, Maddelein D, Hulstaert N, Martens L, Barsnes H, Vaudel M: Pladipus enables universal distributed computing in proteomics bioinformatics. J Proteome Res. 2016 Mar 4;15(3):707-12.

Vaudel M, Verheggen K, Csordas A, Ræder H, Berven FS, Martens L, Vizcaíno JA, Barsnes H: Exploring the potential of public proteomics data. Proteomics. 2016 Jan;16(2):214-25.

Finne K, Marti HP, Leh S, Skogstrand T, Vethe H, Tenstad O, Berven FS, Scherer A, Vikse BE: Proteomic Analysis of Minimally Damaged Renal Tubular Tissue from Two-Kidney-One-Clip Hypertensive Rats Demonstrates Extensive Changes Compared to Tissue from Controls. Nephron. 2016;132(1):70-80.

Sánchez LFH, Aasebø E, Selheim F, Berven F, Ræder H, Barsnes H, Vaudel M:Systemic Analysis of Regulated Functional Networks. Methods Mol Biol. 2016;1394:287-310.

Guldbrandsen A, Barsnes H, Kroksveen AC, Berven F, Vaudel M: A Simple Workflow for Large Scale Shotgun Glycoproteomics. Methods Mol Biol. 2016;1394:275-86.

Aasebø E, Berven FS, Selheim F, Barsnes H, Vaudel M: Interpretation of Quantitative Shotgun Proteomics  Datasets. Methods Mol Biol. 2016;1394:261-73.

Forthun RB, Hinrichs C, Dowling TH, Bruserud Ø, Selheim F: The Past, Present and Future Subclassification of Patients with Acute Myeloid Leukemia. Curr Pharm Biotechnol. 2016;17(1):6-19.

Aasebø E, Forthun RB, Berven F, Selheim F, Hernandez-Valladares M: Global Cell Proteome Profiling, Phospho-signaling and Quantitative Proteomics for Identification of New Biomarkers in Acute Myeloid Leukemia Patients. Curr Pharm Biotechnol. 2016;17(1):52-70.

Selheim F, Herfindal L: EDITORIAL: Toward Personalized Treatment for Acute Myeloid Leukemia. Curr Pharm Biotechnol. 2016;17(1):4-5.

Vaudel M, Barsnes H, Bjerkvig R, Bikfalvi A, Selheim F, Berven FS, Daubon T: Practical Considerations for Omics Experiments in Biomedical Sciences. Curr Pharm Biotechnol. 2016;17(1):105-14.

2015 (18)

Sleire L, Skeie BS, Netland IA, Førde HE, Dodoo E, Selheim F, Leiss L, Heggdal JI, Pedersen PH, Wang J, Enger PØ: Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion. Oncogene 2015 Dec 3;34(49):5951-9.

Kleppe R, Madsen L, Herfindal L, Selheim F, Døskeland SO: Assessing Cyclic Nucleotide Recognition in Cells: Opportunities and Pitfalls for selective Receptor activation. Cyclic Nucleotide signaling, Edited by Xiaodong Cheng, 01/2015: chapter 4; CRC Press, Taylor & Francis, Boca Raton, London, New York., ISBN: 1482235560.

Horvatovich P, Vegvari A, Saul J, Park JG, Qiu J, Syring M, Pirrotte P, Petritis K, Tegeler TJ, Aziz M, Fuentes M, Diez P, Gonzalez-Gonzalez M, Ibarrola N, Droste C, De Las Rivas J, Gil C, Clemente F, Hernáez ML, Corrales FJ, Nilsson CL, Berven FS, Bischoff R, Fehniger TE, LaBaer J, Marko-Varga G.: In vitro transcription translation system: a versatile tool in the search for missing proteins. J Proteome Res. 2015 Sep 4;14(9):3441-51.

Farag Y, Berven FS, Jonassen I, Petersen K, Barsnes H: DiVA: Distributed and interactive visual analysis of omics data. J Proteomics. 2015 Nov 3;129:78-82.

Ann C. Kroksveen, Jacob D. Jaffe, Elise Aasebø, Harald Barsnes, Yngvild Bjørlykke, Diego Franciotta, Hasmik Keshishian, Kjell-Morten Myhr, Jill A. Opsahl, Vincent van Pesch, Charlotte E. Teunissen, Øivind Torkildsen, Rune J. Ulvik, Heidrun Vethe, Steven A. Carr and Frode S. Berven: Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis. Proteomics. 2015 Oct;15(19):3361-9.

Wang X, Zhang Y, Nilsson CL, Berven FS, Andrén PE, Carlsohn E, Malm J, Fuentes M, Végvári Á, Welinder C, Fehniger TE, Rezeli M, Edula G, Hober S, Nishimura T, Marko-Varga G.: Association of chromosome 19 to lung cancer genotypes and phenotypes. Cancer Metastasis Rev. 2015 Jun;34(2):217-26.

Vizcaíno JA, Barsnes H, Hermjakob H: Proteomics data visualization. Proteomics. 2015 Apr;15(8):1339-40.

Kroksveen AC, Opsahl JA, Guldbrandsen A, Myhr KM, Oveland E, Torkildsen Ø, Berven FS. Cerebrospinal fluid proteomics in multiple sclerosis. Biochim Biophys Acta. 2015 Jul;1854(7):746-756.

Vaudel M, Burkhart J, Zahedi RP, Oveland E, Berven FS, Sickmann A, Martens L, Barsnes H: PeptideShaker enables reanalysis of mass spectrometry-derived proteomics datasets. Nature Biotechnol. 2015 Jan;33(1):22–24.

Carol L. Nilsson, Ekaterina Mostovenko, Cheryl F. Lichti, Kelly Ruggles,& David Fenyö,Kate R. Rosenbloom, William S. Hancock Young-Ki Paik, Gilbert S. Omenn, Joshua LaBaer, Roger A. Kroes, Matthias Uhlén, Sophia Hober, Ákos Végvári, Per E. Andrén, Erik P. Sulman, Frederick F. Lang, Manuel Fuentes, Elisabet Carlsohn, Mark R. Emmett, Joseph R. Moskal, Frode S. Berven, Thomas E. Fehniger, and György Marko-Varga: Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome. J Proteome Res. 2015 Feb 6;14(2):603-8.

Oveland E, Muth T, Rapp E, Martens L, Berven FS and Barsnes H: Viewing the Proteome: How to Visualize Proteomics Data? Proteomics. 2015 Apr;15(8):1341-55.

Barsnes H, Vaudel M, Martens L: JSparklines: Making Tabular Proteomics Data Come Alive. Proteomics. 2015 Apr;15(8):1428-31.

Yngvild Bjørlykke, Heidrun Vethe, Marc Vaudel, Harald Barsnes, Frode S. Berven, Erling Tjora, and Helge Raeder: Carboxyl-ester Lipase-Maturity-Onset Diabetes of the Young disease protein biomarkers in secretin-stimulated duodenal juice. J Proteome Res. 2015 Jan 2;14(1):521-30.

Sagstad SJ, Oveland E, Karlsen TV, Haslene-Hox H, Tenstad O, Wiig H: Age-Related Changes in Rat Dermal Extracellular Matrix Composition Affect the Distribution of Plasma Proteins as a Function of Size and Charge. Am J Physiol Heart Circ Physiol. 2015 Jan 1;308(1):H29-38.

Haslene-Hox H, Oveland E, Woie K, Salvesen HB, Tenstad O, Wiig H: Distribution volume of macromolecules in human ovarian and endometrial cancers - effects of extracellular matrix structure. Am J Physiol Heart Circ Physiol. Am J Physiol Heart Circ Physiol. 2015 Jan 1;308(1):H18-28.

Vethe H, Finne K, Skogstrand T, Vaudel M, Vikse BE, Hultström M, Placier S, Scherer A, Tenstad O, Marti HP: Distinct protein signature of hypertension-induced damage in the renal proteome of the two-kidney, one-clip rat model. J Hypertens. 2015 Jan;33(1):126-35.

Hole M, Underhaug J, Diez H, Ying M, Røhr ÅK, Jorge-Finnigan A, Fernàndez-Castillo N, García-Cazorla A, Andersson KK, Teigen K, Martinez A: Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms. Biochim Biophys Acta. 2015 Sep;1854(9):1078-89. (*)

Korner G, Noain D, Ying M, Hole M, Flydal MI, Scherer T, Allegri G, Rassi A, Fingerhut R, Becu-Villalobos D, Pillai S, Wueest S, Konrad D, Lauber-Biason A, Baumann CR, Bindoff LA, Martinez A, Thöny B: Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency. Brain. 2015 Oct;138(Pt 10):2948-63. (*)

2014 (15)

Salwa Suliman, Zhe Xing, Xujun Wu, Ying Xue, Torbjorn O. Pedersen, Yang Sun, Anne P. Døskeland, Joachim Nickel, Thilo Waag, Henning Lygre, Anna Finne-Wistrand, Doris Steinmüller-Nethl, Anke Krueger, Kamal Mustafa: Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo. J Control Release. 2014 Nov 10;197C:148-157.

Finne K, Vethe H, Skogstrand T, Leh S, Dahl TD, Tenstad O, Berven FS, Reed RK, Vikse BE: Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats. Nephrol Dial Transplant. 2014 Dec;29(12):2217-27.

Erik Helgeland, Lars Ertesvåg Breivik, Marc Vaudel, Øyvind Sverre Svendsen, Hilde Garberg, Jan Erik Nordrehaug, Frode Steingrimsen Berven, Anne Kristine Jonassen: Exploring the Human Plasma Proteome for Humoral Mediators of Remote Ischemic Preconditioning - A Word of Caution. PLOS ONE 2014. DOI: 10.1371/journal.pone.0109279.

Aasebø E, Vaudel M, Mjaavatten O, Gausdal G, Van der Burgh A, Gjertsen BT, Døskeland SO, Bruserud O, Berven FS, Selheim F: Performance of Super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines. Proteomics. 2014 Sep;14(17-18):1971-6.

Guldbrandsen A, Vethe H, Farag Y, Garberg H, Berle M, Oveland E, Myhr KM, Opsahl JA, Barsnes H, Berven FS: In-depth characterization of the cerebrospinal fluid proteome including glycosylation patterns and molecular weights as a resource for design of targeted proteomics assays. Mol Cell Proteomics. 2014 Nov;13(11):3152-63.

Nygaard G, Herfindal L, Kopperud R, Aragay AM, Holmsen H, Døskeland SO, Kleppe R, Selheim F: Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. Biochem Biophys Res Commun. 2014 May 17. pii: S0006-291X(14)00886-9.

Haaland I, Opsahl JA, Berven FS, Reikvam H, Fredly HK, Haugse R, Thiede B, McCormack E, Lain S, Bruserud O, Gjertsen BT: Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia. Mol Cancer. 2014 May 21;13(1):116. doi: 10.1186/1476-4598-13-116.

Elise Aasebø, Jill Anette Opsahl, Yngvild Bjørlykke, Kjell-Morten Myhr, Ann Cathrine Kroksveen, Frode S Berven: Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome. PLOS ONE. 2014 Mar 5;9(3):e90429.

Vaudel M, Berven FS, Sickmann A, Martens L, Barsnes H: Shedding light on black boxes in protein identification. Proteomics. 2014 May;14(9):1001-5.

Vaudel M, Barsnes H, Martens L, Berven FS: Bioinformatics for Proteomics: Opportunities at the interface between the scientists, their experiments and the community. Methods Mol Biol. 2014;1156:239-48.

Kelchtermans P, Bittremieux W, De Grave K, Ramon J, Laukens K, Valkenborg D, Barsnes H, Martens L: Machine learning applications in proteomics research. Proteomics. 2014 Mar;14(4-5):353-66.

Verheggen K, Barsnes H, Martens L: Distributed computing and data storage in proteomics: many hands make light work, and a stronger memory. Proteomics. 2014 Mar;14(4-5):367-77.

Muth T, Weilnböck L, Rapp E, Huber C, Martens L, Vaudel M, Barsnes H: DeNovoGUI: an open source graphical user interface for de novo sequencing of tandem mass spectra. J Proteome Res. 2014 Feb 7;13(2):1143-6.

Lichti CF, Liu H, Shavkunov AS, Mostovenko E, Sulman EP, Ezhilarasan R, Wang Q, Kroes R, Moskal JR, Fenyö D, Oksuz BA, Conrad CA, Lang FF, Berven FS, Végvári A, Rezeli M, Marko-Varga G, Hober S, Nilsson CL: Integrated Chromosome 19 Transcriptomic and Proteomic Datasets Derived from Glioma Cancer Stem Cell Lines. J Proteome Res. 2014 Jan 3;13(1):191-9.

Vaudel M, Sickmann A, Martens L: Introduction to opportunities and pitfalls in functional mass spectrometry based proteomics. Biochim Biophys Acta. 2014 Jan;1844(1 Pt A):12-20.

2013 (12)

Malm J, Fehniger TE, Danmyr P, Végvári A, Welinder C, Lindberg H, Appelqvist R, Sjödin K, Wieslander E, Laurell T, Hober S, Berven F, Fenyö D, Wang X, Andrén PE, Edula G, Carlsohn E, Fuentes M, Nilsson C, Dahlbäck M, Rezeli M, Erlinge D, Marko-Varga G: Developments in biobanking workflow standardization providing sample integrity and stability. J Proteomics. 2013 Dec 16;95:38-45.

Hulstaert N, Reisinger F, Rameseder J, Barsnes H, Vizcaíno JA, Martens L: pride-asap: automatic fragment ion annotation of identified PRIDE spectra. J Proteomics. 2013 Dec 16;95:89-92.  

Teunissen C, Menge T, Altintas A, Alvarez-Cermeño JC, Bertolotto A, Berven FS, Brundin L, Comabella M, Degn M, Deisenhammer F, Fazekas F, Franciotta D, Frederiksen JL, Galimberti D, Gnanapavan S, Hegen H, Hemmer B, Hintzen R, Hughes S, Iacobaeus E, Kroksveen AC, Kuhle J, Richert J, Tumani H, Villar LM, Drulovic J, Dujmovic I, Khalil M, Bartos: Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis. Mult Scler. 2013 Nov;19(13):1802-9.

Haslene-Hox H, Oveland E, Woie K, Salvesen HB, Wiig H, Tenstad O: Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue. Biochim Biophys Acta. 2013 Nov;1834(11):2347-59.

Herfindal L, Nygaard G, Kopperud R, Krakstad C, Døskeland SO, Selheim F: Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets. Biochem Biophys Res Commun. 2013 Aug 9;437(4):603-8.

Opsahl JA, Ljostveit S, Solstad T, Risa K, Roepstorff P, Fladmark KE: Identification of dynamic changes in proteins associated with the cellular cytoskeleton after exposure to okadaic acid. Mar Drugs. 2013 May 24;11(6):1763-82.

Berle M, Kroksveen AC, Garberg H, Aarhus M, Haaland OA, Wester K, Ulvik RJ, Helland C, Berven F: Quantitative proteomics comparison of arachnoid cyst fluid and cerebrospinal fluid collected perioperatively from arachnoid cyst patients. Fluids Barriers CNS. 2013 Apr 29;10(1):17.

Barsnes H, Martens L: Crowdsourcing in proteomics: public resources lead to better experiments. Amino Acids. 2013 Apr;44(4):1129-1137.

Myhren LE, Nygaard G, Gausdal G, Sletta H, Teigen K, Degnes KF, Zahlsen K, Brunsvik A, Bruserud O, Døskeland SO, Selheim F, Herfindal L.: Iodinin (1,6-Dihydroxyphenazine 5,10-Dioxide) from Streptosporangium sp. Induces Apoptosis Selectively in Myeloid Leukemia Cell Lines and Patient Cells. Mar Drugs. 2013 Jan 30;11(2):332-49.

Kroksveen AC, Aasebø E, Vethe H, Van Pesch V, Franciotta D, Teunissen C, Ulvik RJ, Vedeler C, Myhr KM, Barsnes H, Berven FS: Discovery and initial verification of differentially abundant proteins between multiple sclerosis patients and controls using iTRAQ and SID-SRM. J. Proteomics. 2013 Jan 14;78:312-25.

Carol L. Nilsson, Frode Berven, Frode Selheim, Huiling Liu, Joseph R. Moskal, Roger A. Kroes, Erik P. Sulman, Charles A. Conrad, Frederick F. Lang, Per E. Andrén, Anna Nilsson, Elisabet Carlsohn, Hans Lilja, Johan Malm, David Fenyö, Devipriya Subramaniyam, Xiangdong Wang, Maria Gonzales-Gonzales, Noelia Dasilva, Paula Diez, Manuel Fuentes, Ákos Végvári, Karin Sjödin, Charlotte Welinder, Thomas Laurell, Thomas E. Fehniger, Henrik Lindberg, Melinda Rezeli, Goutham Edula, Sophia Hober and György Marko-Varga: Chromosome 19 Annotations with Disease Speciation: A First Report from the Global Research Consortium, J. Proteome Res. 2013 Jan 4;12(1):135-50.

Eidhammer I, Barsnes H, Eide GE, Martens L: Computational and Statistical Methods for Protein Quantification by Mass Spectrometry, Wiley, 2013, ISBN: 978-1-1199-6400-1.

2012 (08)

Oveland, Eystein; Karlsen, Tine; Haslene-Hox, Hanne; Semaeva, Elvira; Janaczyk, Bartlomiej; Tenstad, Olav; Wiig, Helge: Proteomic evaluation of inflammatory proteins in rat spleen interstitial fluid and lymph during LPS-induced systemic inflammation reveals increased levels of ADAMST1. J Proteome Res. 2012 Nov 2;11(11):5338-49.

Kroksveen AC, Guldbrandsen A, Vedeler C, Myhr KM, Opsahl JA, Berven FS: Cerebrospinal fluid proteome comparison between multiple sclerosis patients and controls. MS-Acta Neurol Scand Suppl. 2012 Oct 8. pii: S1874-3919(12)00693-8.

Richard G. Côté, Johannes Griss, José A. Dianes, Rui Wang, James C. Wright, Henk W.P. van den Toorn, Bas van Breukelen, Albert J. R. Heck, Niels Hulstaert, Lennart Martens, Florian Reisinger, Attila Csordas, David Ovelleiro, Yasset Perez-Rivevol, Harald Barsnes, Henning Hermjakob and Juan Antonio Vizcaíno: The PRoteomics IDEntification (PRIDE) Converter 2 Framework: An Improved Suite of Tools to Facilitate Data Submission to the PRIDE Database and the ProteomeXchange Consortium. Mol Cell Proteomics. 2012 Dec;11(12):1682-9.

Oveland E, Wergeland L, Hovland R, Lorens JB, Gjertsen BT, Fladmark KE: Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines. Cell Biol Toxicol. 2012 Aug;28(4):201-12.

Aye, Thin Thin; Low, Teck; Bjørlykke, Yngvild; Barsnes, Harald; Heck, Albert; Berven, Frode: Stable isotope dimethyl labeling coupled to selected reaction monitoring enhances throughput by multiplexing relative quantitation of targeted proteins. Anal Chem. 2012 Jun 5;84(11):4999-5006.

Mjaavatten O, Nygaard G, Berven F and Selheim F: Minimization of side reactions during Lys Tag derivatization of C-terminal lysine peptides. Analytica Chimica Acta. 2012 Jan 27;712:101-7.

Sandvig K and Llorente A: Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3. Mol Cell Proteomics. 2012 Jul;11(7):M111.012914. (*)

Koehler CJ, Arntzen MO, Treumann A, Thiede B: Comparison of data analysis parameters and MS/MS fragmentation techniques for quantitative proteome analysis using isobaric peptide termini labeling (IPTL). Anal Bioanal Chem.2012 Sep;404(4):1103-14. (*)

2011 (20)

Kamil A, Falk K, Sharma A, Raae A, Berven FS, Koppang EO, Hordvik I.: A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. Mol Immunol. 2011 Sep;48(15-16):1859-67.

Colaert N., Barsnes H., Vaudel M., Helsens K., Timmerman E., Sickmann A., Gevaert K., Martens L.: thermo-msf-parser: an open source java library to parse and visualize Thermo Proteome Discoverer msf files. J Proteome Res. 2011 Aug 5;10(8):3840-3.

Teunissen C., Tumani H., Bennett J., Berven F.S., et al.: Consensus guidelines for CSF and blood biobanking for CNS biomarker studies. Multiple Sclerosis International, Volume 2011 (2011), Article ID 246412, 9 pages, doi:10.1155/2011/246412.

Fridén V, Oveland E, Tenstad O, Ebefors K, Nyström J, Nilsson UA, Haraldsson B: The glomerular endothelial cell coat is essential for glomerular filtration. Kidney Int. 2011 Jun;79(12):1322-30.

Berle, M; Kroksveen, AC; Haaland, ØA; Aye, TT; Opsahl, JA; Oveland, E; Wester, K; Ulvik, RJ; Helland, CA; Berven, FS: Protein profiling reveals inter-individual protein homogeneity of arachnoid cyst fluid and high qualitative similarity to cerebrospinal fluid. Fluids Barriers CNS. 2011 May 20;8(1):19.

Herfindal L, Myhren L, Kleppe R, Krakstad C, Selheim F, Jokela J, Sivonen K, Døskeland SO: Nostocyclopeptide-M1: A Potent, Nontoxic Inhibitor of the Hepatocyte Drug Transporters OATP1B3 and OATP1B1. Mol Pharm. 2011 Apr 4;8(2):360-7.

Barsnes, H.; Vaudel, M.; Colaert, N.; Helsens, K.; Sickmann, A.; Berven, F.S.; Martens, L.: compomics-utilities: an open-source Java library for computational proteomics. BMC Bioinformatics. 2011 Mar 8;12(1):70.

Barsnes, H.; Eidhammer I.; Martens L.: A global analysis of peptide fragmentation variability. Proteomics. 2011 Mar;11(6):1181-8.

Vaudel M.; Barsnes, H., Berven, F.S.; Sickmann, A; Martens, L.: SearchGUI: An open-source graphical user interface for simultaneous OMSSA and X!Tandem searches. Proteomics 2011. 11(5):996-9.

Arntzen, M.; Koehler, C.; Barsnes, H.; Berven, F; Treumann, A.; Thiede, B.: IsobariQ: software for isobaric quantitative proteomics using IPTL, iTRAQ and TMT. J Proteome Res. 2011 Feb 4;10(2):913-20.

Calvo, A.C.; Pey, A.L.; Miranda-Vizuete, A.; Døskeland, A.P.; Martinez, A.: Divergence in enzyme regulation between C. elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine. Biochem J. 2011 Jan 27;434(1):133-41.

Jensen, B.O, Kleppe R, Kopperud R, Nygard G, Døskeland S.O, Holmsen H and Selheim F: Dipyramidole synergizes with nitric oxide to prfolong inhibition of thrombin-induced platelet shape change in a PKG-independent manner. Platelets 2011;22(1):7-18.

Aurélia E Lewis, Lilly Sommer, Magnus Ø Arntzen, Yvan Strahm, Nicolas A. Morrice, Nullin Divecha and Clive S D’Santos. Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction. Mol Cell Proteomics 2011 Feb;10(2):M110.003376.

Kroksveen A.C.; Opsahl, J.A.; Aye T.T.; Ulvik R.J.; Berven F.S.: Proteomics of human cerebrospinal fluid. Discovery and verification of disease biomarker candidates in neurodegenerative diseases using quantitative proteomics. J Proteomics. 2011 Apr 1;74(4):371-88.

Odd Andre Karlsen, Frode S. Berven, June Iren Bagstevold, Øivind Larsen, and Harald B. Jensen: Methylococcus capsulatus (Bath): From Genome to protein function, and vice versa. Methods Enzymol. 2011;495:63-79.

Odd A. Karlsen, Frode S. Berven, Harald B. Jensen and Anne Fjellbirkeland: Methanotroph outer membrane preparation. Methods Enzymol. 2011;495:167-76.

 Kleppe R, Krakstad C, Selheim F, Kopperud R, and Døskeland SO: The cAMP-dependent protein kinase pathway as therapeutic target – possibilities and pitfalls. Curr Top Med Chem. 2011;11(11):1393-405.

de Souza GA, Arntzen MO, Fortuin S, Schürch AC, Målen H, McEvoy CR, van Soolingen D, Thiede B, Warren RM, Wiker HG: Proteogenomic analysis of polymorphisms and gene annotation divergences in prokaryotes using a clustered mass spectrometry-friendly database. Mol Cell Proteomics. 2011 Jan;10(1):M110.002527.

Ardawatia VV, Masià-Balagué M, Krakstad BF, Johansson BB, Kreitzburg KM, Spriet E, Lewis AE, Meigs TE, Aragay AM: (12) binds to the N-terminal regulatory domain of p120(ctn), and downregulates p120(ctn) tyrosine phosphorylation induced by Src family kinases via a RhoA independent mechanism. Exp Cell Res. 2011 Feb 1;317(3):293-306.

Oftedal L, Skjærven KH, Coyne RT, Edvardsen B, Rohrlack T, Skulberg OM, Døskeland SO, Herfindal L: The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity. J Ind Microbiol Biotechnol. 2011 Apr;38(4):489-501. (*)

2010 (13)

de Souza GA, Fortuin S, Aguilar D, Pando RH, McEvoy CR, van Helden PD, Koehler CJ, Thiede B, Warren RM and Wiker, HG: Using a label-free proteomic method to identify differentially abundant proteins in closely related hypo- and hyper-virulent clinical Mycobacterium tuberculosis Beijingi solates. Mol Cell Proteomics. 2010 Nov; 9(11):2414-23.

Målen, H.; Pathak, S., Søfteland, T.; de Souza, G.A. and Wiker, H.G.: Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv. BMC Microbiol. 2010 Apr 29;10:132.

Jokela J, Herfindal L, Wahlsten M, Permi P, Selheim F, Vasconçelos V, Døskeland SO, Sivonen K.: A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins. Chembiochem. 2010 Jul 26;11(11):1594-9.

Berle M, Wester KG, Ulvik RJ, Kroksveen AC, Haaland OA, Amiry-Moghaddam M, Berven FS, Helland CA: Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults. Cerebrospinal Fluid Res. 2010 Jun 10;7:8.

Rajalahti T, Kroksveen AC, Arneberg R, Berven FS, Vedeler CA, Myhr KM, Kvalheim OM: A multivariate approach to reveal biomarker signatures for disease classification: application to mass spectral profiles of cerebrospinal fluid from patients with multiple sclerosis. J Proteome Res. 2010 Jul 2;9(7):3608-20.

Opsahl JA, Hjørnevik LV, Bull VH, Fismen L, Frøyset AK, Gromyko D, Solstad T, Fladmark KE: Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress. Proteomics. 2010 10,1494-504.

de Souza, G.A.; Arntzen, M.O. and Wiker, H.G. MSMSpdbb: Providing protein databases of closely related organisms to improve proteomic characterization of prokaryotic microbes. Bioinformatics 2010, 26(5), p 698-9, 2010.

Tomazella, G.G.; da Silva, I; Thome, C.H.; Greene, L.J.; Koehler, C.J.; Thiede, B.; Wiker, H.G. and de Souza, G.A.: Analysis of detergent-insoluble and whole cell lysate fractions of resting neutrophils using high-resolution mass spectrometry. J Proteome Res 9(4), p 2030-6, 2010.

Carpenter, J.E.; Jackson, W.; de Souza, G.A.; Haarr, L. and Grose, C.: Insulin degrading enzyme binds to the nonglycosylated precursor of varicella zoster virus gE protein found in the endoplasmic reticulum. J Virology 84(2), p 857-55, 2010.

de Souza, G.A. and Wiker, H.G.: Proteomic approaches to study immunity in infection. Invited as part of book chapter in Methods in Microbiology 37, Eds Dietrich Kabelitz and Stefan Kaufmann. Elsevier p 101-114, 2010.

Aumo L, Rusten M, Mellgren G, Bakke M, Lewis AE: Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. Endocrinology. 2010 May;151(5):2151-61.

Hoivik EA, Lewis AE, Aumo L, Bakke M: Molecular aspects of steroidogenic factor 1 (SF-1). Mol Cell Endocrinol. 2010 Feb 5;315(1-2):27-39.

Linn Oftedal, Frode Selheim, Matti Wahlsten, Kaarina Sivonen, Stein Ove Døskeland, and Lars Herfindal:Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes.Mar. Drugs 2010, 8(10), 2659-2672. 

2009 (09)

Prestegard SK, Oftedal L, Coyne RT, Nygaard G, Skjaerven KH, Knutsen G, Døskeland SO, Herfindal L: Marine benthic diatoms contain compounds able to induce leukemia cell death and modulate blood platelet activity. Mar Drugs. 2009 Nov 18;7(4):605-23.

Birkeland E, Nygaard G, Oveland E, Mjaavatten O, Ljones M, Doskeland SO, Krakstad C and Selheim F.: Epac-induced Alterations in the Proteome of Human SH-SY5Y Neuroblastoma Cells. J Proteomics Bioinform 2009 June 8: 244-254.

Oveland E, Gjertsen BT, Wergeland L, Selheim F, Fladmark KE, Hovland R.: Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells. Leuk Res. 2009 Feb;33(2):276-87

Kellmann R, Schaffner CA, Grønset TA, Satake M, Ziegler M, Fladmark KE.: Proteomic response of human neuroblastoma cells to azaspiracid-1. J Proteomics. 2009 May 2;72(4):695-707.

Tomazella GG, da Silva I, Laure HJ, Rosa JC, Chammas R, Wiker HG, de Souza GA, Greene LJ.: Proteomic analysis of total cellular proteins of human neutrophils. Proteome Sci. 2009 Aug 31;7(1):32.

Pathak S, De Souza GA, Salte T, Wiker HG, Asjö B.: HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells. Scand J Immunol. 2009 Sep;70(3):264-76.

de Souza GA, Søfteland T, Koehler CJ, Thiede B, Wiker HG.: Validating divergent ORF annotation of the Mycobacterium leprae genome through a full translation data set and peptide identification by tandem mass spectrometry.Proteomics. 2009 Jun;9(12):3233-43.

Leversen NA, de Souza GA, Målen H, Prasad S, Jonassen I, Wiker HG.: Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods.Microbiology. 2009 Jul;155(Pt 7):2375-83.

Arntzen  MØ, Osland CL, Rasch-Olsen Raa  C, Kopperud R, Doskeland  SO, Lewis AE, and D’Santos CS: POSTMan (POST-translational Modification analysis); a software application for PTM discovery.Proteomics (2009), 9: 1400–1406.

2008 (07)

Gausdal G, Gjertsen BT, McCormack E, Van Damme P, Hovland R, Krakstad C, Bruserud Ø, Gevaert K, Vandekerckhove J, Døskeland SO: Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death. Blood. 2008 Mar 1;111(5):2866-77. Epub 2008 Jan 8.

Solstad T, Fismen L, Garberg H, Fladmark KE.: Identification of a novel phosphorylation site of acyl-CoA binding protein (ACBP) in nodularin-induced apoptotic hepatocytes.Exp Cell Res. 2008 Jun 10;314(10):2141-9.

Malen H, Berven FS, Softeland T, Arntzen MØ, D’Santos CS, De Souza G and Wiker H.: Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies.Proteomics (2008) 8:1859-70.

Winge I, McKinney JA, Ying M, D'Santos CS, Kleppe R, Knappskog PM and Haavik J.: Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding.Biochemistry Journal. (2008) 410:195-204.

Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J et al.: The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene. 2008 Sep 4;27(39):5182-94.

de Souza GA, Målen H, Søfteland T, Saelensminde G, Prasad S, Jonassen I, Wiker HG.: High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example. BMC Genomics. 2008 Jul 2;9:316.

Målen H, Søfteland T, Wiker HG.: Antigen analysis of Mycobacterium tuberculosis H37Rv culture filtrate proteins.Scand J Immunol. 2008 Mar;67(3):245-52. Epub 2008 Jan 16.

2007 (07)

Flikka K, Meukens J, Helsens K, Vandekerckhove J, Eidhammer I, Gevaert K, Martens L: Implementation and application of a versatile clustering tool for tandem mass spectrometry data. Proteomics. 2007 Sep;7(18):3245-58.

Tait SW, de Vries E, Maas C, Keller AM, D'Santos CS and Borst J.: Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.J Cell Biol. (2007) 179:1453-66.

Kool J, Reubsaet L, Wesseldijk F,  Maravilha RT, Pinkse MW, D’Santos CS, van Hilten R, Zijlstra FJ, and Heck AJ.: Suction blister fluid as a potential biological matrix for biomarker proteins.Proteomics. (2007)  7: 3638-50.

Arneberg R, Rajalahti T, Flikka K, Berven FS, Kroksveen AC, Berle M, Myhr KM, Vedeler CA, Ulvik RJ, Kvalheim OM.: Pretreatment of mass spectral profiles: application to proteomic data.Anal Chem. 2007 Sep 15;79(18):7014-26.

Målen H, Berven FS, Fladmark KE, Wiker HG.: Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv.Proteomics. 2007 May;7(10):1702-18.

Aukrust I, Evensen L, Hollås H, Berven F, Atkinson RA, Travé G, Flatmark T, Vedeler A.: Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation.J Mol Biol. 2006 Oct 20;363(2):469-81.

Berven FS, Kroksveen AC, Berle M, Rajalahti T, Flikka K, Arneberg R, Myhr KM, Vedeler C, Kvalheim OM, Ulvik RJ: Pre-analytical influence on the low molecular weight cerebrospinal fluid proteome. Proteomics Clin Appl Volume 1 Issue 7, Pages 699 - 711.

2006 (15)

Sjøholt, G., Bedringaas, S.L., Døskeland, A.P. and Gjertsen, B.T.: Proteomic Strategies for Individualizing Therapy of Acute Myeloid Leukemia (AML). Curr. Pharm. Biotechnol. 2006; 7:159-170.

Døskeland, A.P.: A method for simple identification of signature peptides derived from polyUb-K48 and K63 by MALDI-TOF MS and chemically assisted MS/MS fragmentation. Amino Acids 2006;30, 99-103.

Krakstad C, Herfindal L, Gjertsen BT, Bøe R, Vintermyr OK, Fladmark KE, Døskeland SO: CaM-kinaseII-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation. Cell Death Differ. 2006 Jul;13(7):1191-202. Epub 2005 Nov 25.

Solstad T, Fladmark KE: Algal toxins as guidance to identify phosphoproteins with key roles in apoptotic cell death. Curr Pharm Biotechnol. 2006 Jun;7(3):209-15.

Oveland E, Fladmark KE, Wergeland L, Gjertsen BT, Hovland R: Proteomics approaches to elucidate oncogenic tyrosine kinase signaling in myeloid malignancies.  Curr Pharm Biotechnol. 2006 Jun;7(3):185-98.

Flikka K, Martens L, Vandekerckhove J, Gevaert K, Eidhammer I. Improving the reliability and throughput of mass spectrometry-based proteomics by spectrum quality filtering. Proteomics. 2006 Apr;6(7):2086-94.

Halstead J, van Rheenen J, Snel M, Meeuws S, Mohammed S, D'Santos CS, Heck AJ, Jalink K and Divecha N.: A Role for PtdIns(4,5)P2 and PIP5K? in Regulating Stress-Induced Apoptosis. Current Biology, (2006) 16: 1850-1856.

Jones D, Bultsma Y, Keune W, Halstead J, Elouarrat D, Mohammed S, Heck AJ, D'Santos CS, and Divecha N.: Nuclear PtdIns5P as a Transducer of Stress Signaling: An In Vivo Role for PIP4Kbeta. Molecular Cell, (2006)  23: 685-695.

Ånensen N, Haaland I, D’Santos CS, Van Belle W, and Gjertsen BT.: Proteomics of p53 in diagnostics and therapy of Acute Myeloid Leukemia. Current Pharmaceutical Biotechnology (2006) 7: 199-207.

Herfindal L and Selheim F.: Microcystin produces disparate effects on liver cells in a dose dependent manner.Mini Rev Med Chem. 2006 Mar;6(3):279-85.

Fladmark  K.E. and Selheim F.: PROBE – nasjonal platform for proteomikk. NBS – nytt 3/2006: 32-35. (without per-reviewer) .

Selheim F.: Proteomic Technologies in Translational medicine. Curr Pharm Biotechnol. 2006 Jun;7(3): (Editorial) 133.

Kleppe R, Kjarland E and Selheim F.: Proteomic and computational methods in systems modeling of cellular signaling. Curr Pharm Biotechnol. 2006 Jun;7(3):135-45.

Berven FS, Flikka K, Berle M, Vedeler C, Ulvik RJ.: Proteomic-based biomarker discovery with emphasis on cerebrospinal fluid and multiple sclerosis.Curr Pharm Biotechnol. 2006 Jun;7(3):147-58.

Berven FS, Karlsen OA, Straume AH, Flikka K, Murrell JC, Fjellbirkeland A, Lillehaug JR, Eidhammer I, Jensen HB.: Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. Arch Microbiol. 2006 Feb;184(6):362-77.

2005 (02)

Herfindal L, Oftedal L, Selheim F, Wahlsten M, Sivonen K, Doskeland SO.: A high proportion of Baltic Sea benthic cyanobacterial Isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes. Toxicon 2005 Sep 1;46(3):252-60.

Selheim F, Herfindal L, Martins R, Vasconcelos V, Døskeland SO.: Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast. Aquat Toxicol. 2005 Sep 30;74(4):294-306.