Addison’s disease, polyendocrine syndromes and beyond- update on research and clinical care

Dear participant

On behalf of the Euradrenal consortium and The Norwegian Endocrine Society, it is a great pleasure for me to welcome to this scientific venue on Addison’s disease at Os outside Bergen Norway.

The meeting will bring together not only the consortium members and their teams, but also leaders in fields related to Addison’s disease from Europe and the United States.

The programme will be a combination of presentations of the latest science, state of the art clinical updates, and interactive workshops with patient organisations as active participators. A poster session will facilitate interaction of faculty and younger scientists. The invited speakers have shown excellence in their respective fields and include the following persons:

• Dr. Jakub Abramson, The Weizmann Institute, Israel
• Prof. Bruno Allolio, University of Wurzburg, Germany
• Prof. Mark Anderson, University of California San Francisco, USA
• Prof. Gudmundur Johannsson, University of Gothenburg, Sweden
• Prof Stafford Lightman, University of Bristol
• Dr. Kerstin Lindblad-Toh, The Broad Institute, Cambridge, Mass, USA and Uppsala University, Sweden
• Prof. Lawrence Nelson, National Institute of Health, Bethesta, USA
• Prof. John Todd, University of Cambridge, UK

The meeting can be viewed as the second in a series of international conferences focusing on autoimmune Addisons disease and polyendocrine syndromes; the first was arranged in Helsinki in 2008 (at the end of FP6 EurAPS).

We plan to further extend this series of international meetings every 4th year.

Scientific Program

Draft schedule

Wednesday 7 March 2012

12.00   Arrival and check-in, refreshments/lunch

13.30   Information from Brussels  Catherine Berens

1^st session: Addresses and introduction

14.00   Welcome  Eystein Husebye, University of Bergen

14.05  An overview of Euradrenal achievements Eystein Husebye, University of Bergen

14.30   Autoimmune Addison’s disease, state-of-the-art Olle Kämpe, Uppsala Universitetet

15.10   State-of-the art diagnosis and follow-up of Addison’s disease – the Euradrenal consensus Alberto Falorni, University of Perugia

16.00   COFFEE

Parallel sessions

2^nd session: Genetics of autoimmune diseases

16.30   Common susceptibility genes in autoimmune disorders - HLA and other examples

              John Todd, University of Cambridge

17.30   Genetics of autoimmune Addison’s disease and polyendocrine syndromes

               Simon Pearce, University of Newcastle

3^rd  session: General assembly of The Norwegian Endocrine Society (NES)

16.30   For members of The Norwegian Endocrine Society, see separate agenda

19.00   DINNER

 Thursday 8 March 2012

 4^th session: Autoimmune polyendocrine syndrome type 1

08.30   Lessons learned from Aire knockout mouse models 

              Mark Anderson, UCSF

09.20   Autoimmune regulator and its partners, insights into how Aire regulates transcription 

          Jakub Abramson, The Weizmann Institute

10.10   COFFEE AND POSTERS

Parallel sessions

5^th session: Animal models of autoimmune diseases

10.40   Canine models of endocrine diseases                       

              Kerstin Lindblad-Toh, The Broad Institute, alt. William Ollier, University of Manchester

11.30   Novel experimental mouse models of Addison’s disease

             Georg Holländer, University of Basel

6^th session: Oral presentations

10.40   6 presentations of 10+5 minutes

12.15   LUNCH

7^th session: Natural course of Addison’s disease and autoimmune ovarian insufficiency

13.15   Epidemiology and mortality              

              Sophie Bensing/Anna-Lena Hulting, Karolinska Institute

13.45   Autoimmune Lymphocytic Oophoritis,

             Lawrence Nelson, National Institute of Health

14.30  Coffee

14.45   Acute adrenal failure

               Bruno Allolio, University of Würzburg

15.30   Quality of life

               Kristian Løvås, University of Bergen 

16.00   COFFEE AND POSTERS

8^th session: Cortisol effects

17.00   Why is ultradian rhythmicity such an important aspect of the

           circadian glucocorticoid rhythm?

           Stafford Lightman, University of Bristol

19.00   DINNER AND MORE

Friday 9 March 2012

9^th session: Novel treatment modalities in Addison’s disease 

08.30   Slow release hydrocortisone

               Gudmundur Johannsson, University of Gothenburg

09.10   Subcutanous hydrocortisone treatment

              Marianne Øksnes, University of Bergen

09.50   COFFEE

Parallel sessions

10^th session: Immunopathology of Addison’s disease

1015    The role of the adrenocortical cell in the pathogenesis of Addison’s disease           

              Eirik Bratland, University of Bergen

1045    The role of vitamin D in autoimmune disease

              Klaus Badenhoop, University of Frankfurt

1115    The role of 21-hydroxylase antibodies in pathogenesis revisited

            Olle Kämpe, Uppsala University

1145    Characterization of T cell epitopes in 21-hydroxylase

                Vincenzo Cerundolo, University of Oxford

11^th session: Work shop with patient organisations

1015    Use of social media in patient care and education

           Berit Borhaug, The Norwegian Addison Association

            Jette Kristensen, The Danish Addison Association

1115    Patient care across Europe

            Katherine White, The Addisons Self Help Group UK

1145    Patient emergency card

            Eva Rafner, The Swedish Addison Association

12^th session: Clinical cases day

1015    8 presentations of 10+5 minutes

12.30   LUNCH AND DEPARTURE

Confirmed international speakers

Jakub Abramson, The Weizmann Institute, Israel

Bruno Allolio, University of Wurzburg, Germany

Mark Anderson, University of California, San Francisco, USA

Gudmundur Johannsson, University of Gothenburg

Kerstin Lindblad-Toh, The Broad Institute, Cambridge, Massachusetts, USA

Stafford Lightman, University of Bristol, UK

Lawrence Nelson, National Institute of Health, Bethesda, USA

John Todd, University of Cambridge, UK

Registration and practical information

The symposium will take place at Solstrand Hotel & Bad .

Solstrand Hotel & Bad is situated right by the fjord only 30 km south of Bergen and the airport.

Online registration for the symposium will be open 1 November 2011.

The deadline for registration has now passed, however there are still a few spots available.

For registration enquiry, please contact Alexander Hellesen at rhe062@med.uib.no.

Registration fee for Hotel & dinner includes

• admission to the symposium
• program
• tea/coffe/lunch
• accommodation ( 2 nights 7-9 March)

Early registration: 4700NOK, normal registration fee: 4950NOK

Registration fee for admission and lunch includes

• admission to the symoposium
• program
• tea/coffe/lunch

Early registration: 1300NOK, normal registration fee:1450NOK

Transport from/to Bergen Airport Flesland

Informasjon + Link?

Poster sessions and oral presentations

Participants are welcome to present their research in the form of posters or oral presentations. Abstracts to be evaluated for presentation are to be submitted online through the link below.

Submission deadline: 15th of February

Abstract submission: https://reg.app.uib.no/euradrenal/

Organizing Committee and Contact

Eystein Husebye, University of Bergen, Chair

Klaus Badenhoop, University of Frankfurt, Germany

Alberto Falorni, University of Perugia, Italy

Georg Holländer, University of Basel, Switzerland

Anna-Lena Hulting, Karolinska Institutet, Sweden

Simon Pearche, University of Newcastle, UK

Olle Kämpe, Uppsala University

Anders Jørgensen, President, The Norwegian Endocrine Society

Contact:

Professor Eystein Husebye

Institute of Medicine, University of Bergen

Haukeland University Hospital

5020 Bergen

Norway

Phone: +47 55 97 3078

Email: Eystein.Husebye@med.uib.no

            post@euradrenal.org

Bergen Kongress & Kultur  AS

Torgallmenningen 1A

Postboks 947 Sentrum

5808 Bergen

Norway

Phone: +47 55 55 36 55

Email: email@kongress.no

Social Program

1. Hurtigruten - The Costal Steamer to Trondheim
2. Ski Weekend at Geilo, 3,5 h from Bergen.
   
3. Norway in a Nutshell  -  1 day tour on the Western area of Nordway, Fjords and Mountains.