Hjem
Frode Bervens bilde

Frode Berven

Professor
  • E-postFrode.Berven@uib.no
  • Telefon+47 55 58 67 43+47 991 63 866
  • Besøksadresse
    Jonas Lies vei 91
  • Postadresse
    Postboks 7804
    5020 Bergen

Dr. Frode S. Berven (Ph.D.) is the head of the Proteomics Unit at the University of Bergen.

Berven completed his Masters degree at Department of Molecular Biologi, UiB, Ph.D. in bioinformatics at the Department of Informatics, UiB, and post doctor at the Institute of Medicine, UiB, and at the Proteomics Platform at the Broad Institute of MIT and Harvard.

He is working in the field of mass spectrometry based quantitative proteomics with emphaisis on biomarker disocovery and verification in cerebrospinal fluid of patients with multiple sclerosis.

Tidsskriftartikler
  • Bjørkum, Alvhild Alette; Oveland, Eystein; Stuhr, Linda Elin Birkhaug; Havnes, Marianne Bjordal; Berven, Frode; Grønning, Marit; Hope, Arvid. 2017. Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. PLoS ONE. 12: 1-16. doi: 10.1371/journal.pone.0185765
  • Brenner, Annette; Aasebø, Elise; Hernandez-Valladares, Maria; Selheim, Frode; Berven, Frode; Bruserud, Øystein. 2017. Rethinking the role of osteopontin in human acute myeloid leukemia. Leukemia and Lymphoma. 58: 1494-1497. doi: 10.1080/10428194.2016.1243682
  • Hernandez-Valladares, Maria; Vaudel, Marc; Selheim, Frode; Berven, Frode; Bruserud, Øystein. 2017. Proteogenomics approaches for studying cancer biology and their potential in the identification of acute myeloid leukemia biomarkers. Espert Review of Proteomics. 14: 649-663. doi: 10.1080/14789450.2017.1352474
  • Kroksveen, Ann Cathrine; Guldbrandsen, Astrid; Vaudel, Marc; Lereim, Ragnhild Reehorst; Barsnes, Harald; Myhr, Kjell-Morten; Torkildsen, Øivind; Berven, Frode. 2017. In-depth cerebrospinal fluid quantitative proteome and deglycoproteome analysis: presenting a comprehensive picture of pathways and processes affected by multiple sclerosis. Journal of Proteome Research. 16: 179-194. doi: 10.1021/acs.jproteome.6b00659
  • Nygaard, Gyrid; Herfindal, Lars; Sivertsen Åsrud, Kathrine; Bjørnstad, Ronja; Kopperud, Reidun Kristin; Oveland, Eystein; Berven, Frode; Myhren, Lene Elisabeth; Høivik, Erling Andre; Lunde, Turid Helen Felli; Bakke, Marit; Doskeland, Stein Ove; Selheim, Frode. 2017. Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression. Scientific Reports. 7:8725: 1-15. doi: 10.1038/s41598-017-08975-y
  • Yadetie, Fekadu; Oveland, Eystein; Døskeland, Anne Marie Simonne; Berven, Frode; Goksøyr, Anders; Karlsen, Odd Andre. 2017. Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. Aquatic Toxicology. 185: 19-28. doi: 10.1016/j.aquatox.2017.01.014
  • Aasebø, Elise; Forthun, Rakel Brendsdal; Berven, Frode; Selheim, Frode; Hernandez-Valladares, Maria. 2016. Global cell proteome profiling, phospho-signaling and quantitative proteomics for identification of new biomarkers in acute myeloid leukemia patients. Current Pharmaceutical Biotechnology. 17: 52-70. doi: 10.2174/1389201016666150826115626
  • Aasebø, Elise; Mjaavatten, Olav; Vaudel, Marc; Farag, Yehia Mohamed Mokhtar; Selheim, Frode; Berven, Frode; Bruserud, Øystein; Hernandez-Valladares, Maria. 2016. Freezing effects on the acute myeloid leukemia cell proteome and phosphoproteome revealed using optimal quantitative workflows. Journal of Proteomics. 145: 214-225. doi: 10.1016/j.jprot.2016.03.049
  • Finne, Kenneth; Marti, Hans-Peter; Leh, Sabine Maria; Skogstrand, Trude; Vethne, Heidrun; Tenstad, Olav; Berven, Frode; Scherer, Andreas; Vikse, Bjørn Egil. 2016. Proteomic Analysis of Minimally Damaged Renal Tubular Tissue from Two-Kidney-One-Clip Hypertensive Rats Demonstrates Extensive Changes Compared to Tissue from Controls. Nephron. 132: 70-80. doi: 10.1159/000442825
  • Guldbrandsen, Astrid; Farag, Yehia Mohamed Mokhtar; Kroksveen, Ann Cathrine; Oveland, Eystein; Lereim, Ragnhild Reehorst; Opsahl, Jill Anette; Myhr, Kjell-Morten; Berven, Frode; Barsnes, Harald. 2016. CSF-PR 2.0: an interactive literature guide to quantitative cerebrospinal fluid mass spectrometry data from neurodegenerative disorders. Molecular & Cellular Proteomics. 16: 300-309. doi: 10.1074/mcp.O116.064477
  • Hernandez Sanchez, Luis Francisco; Aasebø, Elise; Selheim, Frode; Berven, Frode; Ræder, Helge; Barsnes, Harald; Vaudel, Marc. 2016. Systemic Analysis of Regulated Functional Networks. Methods in Molecular Biology. 1394: 287-310. doi: 10.1007/978-1-4939-3341-9_21
  • Hernandez-Valladares, Maria; Aasebø, Elise; Mjaavatten, Olav; Vaudel, Marc; Bruserud, Øystein; Berven, Frode; Selheim, Frode. 2016. Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients. Biological Procedures Online. 18:13: 1-10. doi: 10.1186/s12575-016-0043-0
  • Lereim, Ragnhild Reehorst; Oveland, Eystein; Xiao, Y.; Torkildsen, Øivind; Wergeland, Stig; Myhr, Kjell-Morten; Sun, Shao-Cong; Berven, Frode. 2016. The Brain Proteome of the Ubiquitin Ligase Peli1 Knock-Out Mouse during Experimental Autoimmune Encephalomyelitis. Journal of Proteomics & Bioinformatics. doi: 10.4172/jpb.1000408
  • Opsahl, Jill Anette; Vaudel, Marc; Guldbrandsen, Astrid; Aasebø, Elise; Van Pesch, Vincent; Franciotta, Diego; Myhr, Kjell-Morten; Barsnes, Harald; Berle, Magnus Foldal; Torkildsen, Øivind; Kroksveen, Ann Cathrine; Berven, Frode. 2016. Label-free analysis of human cerebrospinal fluid addressing various normalization strategies and revealing protein groups affected by multiple sclerosis. Proteomics. 16: 1154-1165. doi: 10.1002/pmic.201500284
  • Vaudel, Marc; Barsnes, Harald; Bjerkvig, Rolf; Bikfalvi, Andreas; Selheim, Frode; Berven, Frode; Daubon, Thomas. 2016. Practical considerations for omics experiments in biomedical sciences. Current Pharmaceutical Biotechnology. 17: 105-114. doi: 10.2174/1389201016666150817095348
  • Vaudel, Marc; Barsnes, Harald; Ræder, Helge; Berven, Frode. 2016. Using Proteomics Bioinformatics Tools and Resources in Proteogenomic Studies. Advances in Experimental Medicine and Biology. 926: 65-75. doi: 10.1007/978-3-319-42316-6_5
  • Vaudel, Marc; Verheggen, Kenneth; Csordas, Attila; Ræder, Helge; Berven, Frode; Martens, Lennart; Vizcaíno, Juan Antonio; Barsnes, Harald. 2016. Exploring the potential of public proteomics data. Proteomics. 16: 214-225. doi: 10.1002/pmic.201500295
  • Yadetie, Fekadu; Bjørneklett, Silje; Garberg, Hilde Kristin; Oveland, Eystein; Berven, Frode; Goksøyr, Anders; Karlsen, Odd Andre. 2016. Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. BMC Genomics. 17:554: 1-15. doi: 10.1186/s12864-016-2864-2
  • Farag, Yehia Mohamed Mokhtar; Berven, Frode; Jonassen, Inge; Petersen, Kjell; Barsnes, Harald. 2015. Distributed and interactive visual analysis of omics data. Journal of Proteomics. 129: 78-82. doi: 10.1016/j.jprot.2015.05.029
  • Horvatovich, Péter; Végvári, Ákos; Saul, Justin; Park, Jin G.; Qiu, Ji; Syring, Michael; Pirrotte, Patrick; Petritis, Konstantinos; Tegeler, Tony J.; Aziz, Meraj; Fuentes, Manuel; Diez, Paula; Gonzalez-Gonzalez, Maria; Ibarrola, Nieves; Droste, Conrad; De Las Rivas, Javier; Gil, Concha; Clemente, Felipe; Hernaez, Maria Luisa; Corrales, Fernando J.; Nilsson, Carol L.; Berven, Frode; Bischoff, Rainer; Fehniger, Thomas E.; LaBaer, Joshua; Marko-Varga, György. 2015. In vitro transcription/translation system: A versatile tool in the search for missing proteins. Journal of Proteome Research. 14: 3441-3451. doi: 10.1021/acs.jproteome.5b00486
  • Kroksveen, Ann Cathrine; Jaffe, Jacob D.; Aasebø, Elise; Barsnes, Harald; Bjørlykke, Yngvild; Franciotta, Diego; Keshishian, Hasmik; Myhr, Kjell-Morten; Opsahl, Jill Anette; van Pesch, Vincent; Teunissen, Charlotte E.; Torkildsen, Øivind; Ulvik, Rune Johan; Vethne, Heidrun; Carr, Steven A.; Berven, Frode. 2015. Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis. Proteomics. 15: 3361-3369. doi: 10.1002/pmic.201400142
  • Kroksveen, Ann Cathrine; Opsahl, Jill Anette; Guldbrandsen, Astrid; Myhr, Kjell-Morten; Oveland, Eystein; Torkildsen, Øivind; Berven, Frode. 2015. Cerebrospinal fluid proteomics in multiple sclerosis. Biochimica et Biophysica Acta - Proteins and Proteomics. 1854: 746-756. doi: 10.1016/j.bbapap.2014.12.013
  • Nilsson, Carol L.; Mostovenko, Ekaterina; Lichti, Cheryl F.; Ruggles, Kelly; Fenyö, David; Rosenbloom, Kate R.; Hancock, William S.; Paik, Young-Ki; Omenn, Gilbert S.; LaBaer, Joshua; Kroes, Roger A.; Uhlén, Mathias; Hober, Sophia; Végvári, Ákos; Andrén, Per E.; Sulman, Erik P.; Lang, Frederick F.; Fuentes, Manuel; Carlsohn, Elisabet; Emmett, Mark R.; Moskal, Joseph R.; Berven, Frode; Fehniger, Thomas E.; Marko-Varga, György. 2015. Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome. Journal of Proteome Research. 14: 603-608. doi: 10.1021/pr500564q
  • Oveland, Eystein; Muth, Thilo; Rapp, Erdmann; Martens, Lennart; Berven, Frode; Barsnes, Harald. 2015. Viewing the proteome: How to visualize proteomics data? Proteomics. 15: 1341-1355. doi: 10.1002/pmic.201400412
  • Vaudel, Marc; Burkhart, Julia M.; Zahedi, René P.; Oveland, Eystein; Berven, Frode; Sickmann, Albert; Martens, Lennart; Barsnes, Harald. 2015. PeptideShaker enables reanalysis of MS-derived proteomics data sets. Nature Biotechnology. 33: 22-24. doi: 10.1038/nbt.3109
  • Wang, Xiangdong; Zhang, Yong; Nilsson, Carol L.; Berven, Frode; Andrén, Per E.; Carlsohn, Elisabet; Horvatovich, Peter; Malm, Johan; Fuentes, Manuel; Végvári, Ákos; Welinder, Charlotte; Fehniger, Thomas E.; Rezeli, Melinda; Edula, Goutham; Hober, Sophia; Nishimura, Toshihide; Marko-Varga, György. 2015. Association of chromosome 19 to lung cancer genotypes and phenotypes. Cancer Metastasis Review. 34: 217-226. doi: 10.1007/s10555-015-9556-2
  • Wang, Xiangdong; Zhang, Yong; Nilsson, Carol L.; Berven, Frode; Andrén, Per E.; Carlsohn, Elisabet; Horvatovich, Peter; Malm, Johan; Fuentes, Manuel; Végvári, Ákos; Welinder, Charlotte; Fehniger, Thomas E.; Rezeli, Melinda; Edula, Goutham; Hober, Sophia; Nishimura, Toshihide; Marko-Varga, György. 2015. Erratum to: Association of chromosome 19 to lung cancer genotypes and phenotypes. Cancer Metastasis Review. 34: 227-227. doi: 10.1007/s10555-015-9571-3
  • Wheelock, Åsa M.; Paulson, Linda; Litton, Jan-Eric; Berven, Frode. 2015. The EuPA Biobank Initiative: Meeting the future challenges of biobanking in proteomics & systems medicine. Journal of Proteomics. 127: 414-416. doi: 10.1016/j.jprot.2015.07.014
  • Aasebø, Elise; Opsahl, Jill Anette; Bjørlykke, Yngvild; Myhr, Kjell-Morten; Kroksveen, Ann Cathrine; Berven, Frode. 2014. Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome. PLoS ONE. 9. doi: 10.1371/journal.pone.0090429
  • Aasebø, Elise; Vaudel, Marc; Mjaavatten, Olav; Gausdal, Gro; van der Burgh, Arthur Edward Emiel; Gjertsen, Bjørn Tore; Doskeland, Stein Ove; Bruserud, Øystein; Berven, Frode; Selheim, Frode. 2014. Performance of super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines. Proteomics. 14: 1971-1976. doi: 10.1002/pmic.201300448
  • Bjørlykke, Yngvild; Vethne, Heidrun; Vaudel, Marc; Barsnes, Harald; Berven, Frode; Tjora, Erling; Ræder, Helge. 2014. Carboxyl-ester lipase maturity-onset diabetes of the young disease protein biomarkers in secretin-stimulated duodenal juice. Journal of Proteome Research. 14: 521-530. doi: 10.1021/pr500750z
  • Finne, Kenneth; Vethne, Heidrun; Skogstrand, Trude; Leh, Sabine Maria; Dahl, Tone Dolva; Tenstad, Olav; Berven, Frode; Reed, Rolf K.; Vikse, Bjørn Egil. 2014. Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats. Nephrology, Dialysis and Transplantation. 11 sider. doi: 10.1093/ndt/gfu268
  • Guldbrandsen, Astrid; Vethne, Heidrun; Farag, Yehia Mohamed Mokhtar; Oveland, Eystein; Garberg, Hilde Kristin; Berle, Magnus Foldal; Myhr, Kjell-Morten; Opsahl, Jill Anette; Barsnes, Harald; Berven, Frode. 2014. In-depth characterization of the cerebrospinal fluid (CSF) proteome displayed through the CSF proteome resource (CSF-PR). Molecular & Cellular Proteomics. 13: 3152-3163. doi: 10.1074/mcp.M114.038554
  • Haaland, Ingvild; Opsahl, Jill Anette; Berven, Frode; Reikvam, Håkon; Fredly, Hanne Kristin; Haugse, Ragnhild; Thiede, Bernd; McCormack, Emmet; Lain, Sonia; Bruserud, Øystein; Gjertsen, Bjørn Tore. 2014. Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia. Molecular Cancer. 13. doi: 10.1186/1476-4598-13-116
  • Helgeland, Erik; Breivik, Lars Ertesvåg; Vaudel, Marc; Svendsen, Øyvind Sverre; Garberg, Hilde Kristin; Nordrehaug, Jan Erik; Berven, Frode; Jonassen, Anne K. 2014. Exploring the human plasma proteome for humoral mediators of remote ischemic preconditioning - A word of caution. PLoS ONE. 9. doi: 10.1371/journal.pone.0109279
  • Lichti, Cheryl F.; Liu, Huiling; Shavkunov, Alexander S.; Mostovenko, Ekaterina; Sulman, Erik P.; Ezhilarasan, Ravesanker; Wang, Quianghu; Kroes, Roger A.; Moskal, Joseph c.; Fenyö, David; Oksuz, Betül Akgöl; Conrad, Charles A.; Lang, Frederick F.; Berven, Frode; Végvári, Ákos; Rezeli, Melinda; Marko-Varga, György; Hober, Sophia; Nilsson, Carol L. 2014. Integrated chromosome 19 transcriptomic and proteomic data sets derived from glioma cancer stem-cell lines. Journal of Proteome Research. 13: 191-199. doi: 10.1021/pr400786s
  • Vaudel, Marc; Venne, A. Saskia; Berven, Frode; Zahedi, René P.; Martens, Lennart; Barsnes, Harald. 2014. Shedding light on black boxes in protein identification. Proteomics. 14: 1001-1005. doi: 10.1002/pmic.201300488
  • Berle, Magnus Foldal; Kroksveen, Ann Cathrine; Garberg, Hilde Kristin; Aarhus, Mads; Haaland, Øystein; Wester, Knut; Ulvik, Rune Johan; Helland, Christian Andre; Berven, Frode. 2013. Quantitative proteomics comparison of arachnoid cyst fluid and cerebrospinal fluid collected perioperatively from arachnoid cyst patients. Fluids and Barriers of the CNS. 10. doi: 10.1186/2045-8118-10-17
  • Finne, Kenneth; Skogstrand, Trude; Tenstad, Olav; Berven, Frode; Hultström, Michael; Vethe, Heidrun; Vikse, Bjørn Egil. 2013. Proteomic analysis of outer and juxtamedullary cortex of non-clipped kidneys in 2K1C hypertensive rats. The FASEB Journal. 27:909.15. 1 sider.
  • Kroksveen, Ann Cathrine; Aasebø, Elise; Vethe, Heidrun; van Pesch, Vincent; Franciotta, Diego; Teunissen, Charlotte E.; Ulvik, Rune Johan; Vedeler, Christian A.; Myhr, Kjell-Morten; Barsnes, Harald; Berven, Frode. 2013. Discovery and initial verification of differentially abundant proteins between multiple sclerosis patients and controls using iTRAQ and SID-SRM. Journal of Proteomics. 78: 312-325. doi: 10.1016/j.jprot.2012.09.037
  • Malm, Johan; Fehninger, T.E.; Danmyr, Pia; Végvári, Ákos; Welinder, Charlotte; Lindberg, Henrik; APPELQVIST, ROGER; Sjödin, Karin; WIESLANDER, ELISABET; Laurell, Thomas; Hober, Sophia; Berven, Frode; Fenyö, David; Wang, Xiangdong; Andrén, Per E.; Edula, Goutham; Carlsohn, Elisabet; Fuentes, Manuel; Nilsson, Carol L.; Dahlbäck, MAGNUS; Rezeli, Melinda; Erlinge, David; Marko-Varga, Gyorgy. 2013. Developments in biobanking workflow standardization providing sample integrity and stability. Journal of Proteomics. 95: 38-45. doi: 10.1016/j.jprot.2013.06.035
  • Nilsson, Carol L.; Berven, Frode; Selheim, Frode; Liu, Huiling; Moskal, Joseph R.; Kroes, Roger A.; Sulman, Erik P.; Conrad, Charles A.; Lang, Frederick F.; Andrén, Per E.; Nilsson, Anna; Carlsohn, Elisabet; Lilja, Hans; Malm, Johan; Fenyö, David; Subramaniyam, Devipriya; Wang, Xiangdong; Gonzales-Gonzales, Maria; Dasilva, Noelia; Diez, Paula; Fuentes, Manuel; Végvári, Ákos; Sjödin, Karin; Welinder, Charlotte; Laurell, Thomas; Fehniger, Thomas E.; Lindberg, Henrik; Rezeli, Melinda; Edula, Goutham; Hober, Sophia; Marko-Varga, Györgi. 2013. Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium. Journal of Proteome Research. 12: 134-149. doi: 10.1021/pr3008607
  • Teunissen, Charlotte E.; Menge, Til; Altintas, Ayse; Álvarez-Cermeño, José C; Bertolotto, Antonio; Berven, Frode; Brundin, Lou; Comabella, Manuel; Degn, Matilde; Deisenhammer, Florian; Fazekas, Franz; Franciotta, Diego; Frederiksen, Jette Lautrup; Galimberti, Daniela; Gnanapavan, Sharmilee; Hegen, Harald; Hemmer, Bernhard; Hintzen, Rogier; Hughes, Steve G.; Iacobaeus, Ellen; Kroksveen, Ann Cathrine; Kuhle, Jens; Richert, John; Tumani, Hayrettin; Villar, Luisa Maria; Drulovic, Jelena; Dujmovic, Irena; Khalil, Michael; Bartos, Ales. 2013. Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis. Multiple Sclerosis. 19: 1802-1809. doi: 10.1177/1352458513488232
  • Aye, Thin Thin; Low, Teck Yew; Bjørlykke, Yngvild; Barsnes, Harald; Heck, Albert J.R.; Berven, Frode. 2012. Use of stable isotope dimethyl labeling coupled to selected reaction monitoring to enhance throughput by multiplexing relative quantitation of targeted proteins. Analytical Chemistry. 84: 4999-5006. doi: 10.1021/ac300596r
  • Kroksveen, Ann Cathrine; Guldbrandsen, Astrid; Vedeler, Christian A.; Myhr, Kjell-Morten; Opsahl, Jill Anette; Berven, Frode. 2012. Cerebrospinal fluid proteome comparison between multiple sclerosis patients and controls. Acta Neurologica Scandinavica. 126: 90-96. doi: 10.1111/ane.12029
  • Mjaavatten, Olav; Nygaard, Gyrid; Berven, Frode; Selheim, Frode. 2012. Minimization of side reactions during Lys Tag derivatization of C-terminal lysine peptides. Analytica Chimica Acta. 712: 101-107. doi: 10.1016/j.aca.2011.11.017
  • Arntzen, Magnus; Koehler, Christian; Barsnes, Harald; Berven, Frode; Treumann, Achim; Thiede, Bernd. 2011. IsobariQ: Software for Isobaric Quantitative Proteomics using IPTL, iTRAQ, and TMT. Journal of Proteome Research. 10: 913-920. doi: 10.1021/pr1009977
  • Barsnes, Harald; Vaudel, Marc; Colaert, Niklaas; Helsens, Kenny; Sickmann, Albert; Berven, Frode; Martens, Lennart. 2011. compomics-utilities: an open-source Java library for computational proteomics. BMC Bioinformatics. 12. 5 sider. doi: 10.1186/1471-2105-12-70
  • Berle, Magnus Foldal; Kroksveen, Ann Cathrine; Haaland, Øystein; Aye, Thin Thin; Opsahl, Jill Anette; Wester, Knut; Ulvik, Rune Johan; Helland, Christian Andre; Berven, Frode. 2011. Protein profiling reveals inter-individual protein homogeneity of arachnoid cyst fluid and high qualitative similarity to cerebrospinal fluid. Fluids and Barriers of the CNS. 8. doi: 10.1186/2045-8118-8-19
  • Eijsink, Vincent; Berven, Frode. 2011. The field of proteomics in Norway. Public Service Review : European Union. 21.
  • Kamil, Atif; Falk, Knut; Sharma, Animesh; Raae, Arnt Johan; Berven, Frode; Koppang, Erling Olaf; Hordvik, Ivar. 2011. A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. Molecular Immunology. doi: 10.1016/j.molimm.2011.05.005
  • Karlsen, Odd Andre; Berven, Frode; Bagstevold, June Iren Larsen|; Larsen, Øivind; Jensen, Harald B. 2011. Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. Methods in Enzymology. 495: 63-79. doi: 10.1016/B978-0-12-386905-0.00005-X
  • Karlsen, Odd Andre; Berven, Frode; Jensen, Harald B; Fjellbirkeland, Anne. 2011. METHANOTROPH OUTER MEMBRANE PREPARATION. Methods in Enzymology. 167-176. doi: 10.1016/B978-0-12-386905-0.00011-5
  • Kroksveen, Ann Cathrine; Opsahl, Jill Anette; Aye, Thin Thin; Ulvik, Rune Johan; Berven, Frode. 2011. Proteomics of human cerebrospinal fluid: Discovery and verification of disease biomarker candidates in neurodegenerative diseases using quantitative proteomics. Journal of Proteomics. 74: 371-388. doi: 10.1016/j.jprot.2010.11.010
  • Vaudel, Marc; Barsnes, Harald; Berven, Frode; Sickmann, Albert; Martens, Lennart Martens. 2011. SearchGUI: An open-source graphical user interface for simultaneous OMSSA and X!Tandem searches. Proteomics. 11: 996-999. doi: 10.1002/pmic.201000595
  • Berle, Magnus Foldal; Wester, Knut; Ulvik, Rune Johan; Haaland, Øystein Ariansen; Kroksveen, Ann Cathrine; Amiry-Moghaddam, Mahmood; Berven, Frode; Helland, Christian Andre. 2010. Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults. Cerebrospinal Fluid Research. 7.
  • Berven, Frode; Ahmad, Rushdy; Clouser, Karl R.; Carr, Steven A. 2010. Optimizing performance of glycopeptide capture for plasma proteomics. Journal of Proteome Research. 9: 1706-1715. doi: 10.1021/pr900845m
  • Kvalheim, Tarja Anniki Rajalahti; Kroksveen, Ann Cathrine; Arneberg, Reidar; Berven, Frode; Vedeler, Christian A.; Myhr, Kjell-Morten; Kvalheim, Olav Martin. 2010. A multivariate approach to reveal biomarker signatures for disease classification: application to mass spectral profiles of cerebrospinal fluid from patients with multiple sclerosis. Journal of Proteome Research. 9: 3608-3620. doi: 10.1021/pr100142m
  • Teunissen, Charlotte E.; Petzold, Axel; Bennett, Jeffrey L.; Berven, Frode; Brundin, Lou; Comabella, Manuel; Franciotta, Diego; Federiksen, Jette L.; Fleming, John O.; Furlan, Robert; Hintzen, Rogier Q.; Hughes, Steve G.; Johnson, Michael H.; Krasulova, Eva; Kuhle, Jens; Magnone, Maria-Chiara; Rajda, Cecilia; Rejdak, Konrad; Schmidt, Holly K.; van Pesch, Vincent; Waubant, Emmanuelle; Wolf, Christian; Giovannoni, Gavin; Deisenhammer, Florian; Hegen, Harald; Hemmer, Bernhard; Tumani, Hayrettin. 2010. A consensus protocol for the standardisation of cerebrospinal fluid collection and biobanking. Laboratoriums Medizin. 34: 1-12. doi: 10.1515/JLM.2010.001
  • Teunissen, Charlotte; Tumani, HT; Bennett, JL; Berven, Frode; Brundin, L; Comabella, M; Franciotta, D; Federiksen, Jette L.; Fleming, John O.; Furlan, R; Hintzen, R; Hughes, SG; Johnson, MH; Krasulova, E; Kuhle, Jens; Magnone, Maria-Chiara; Petzold, A; Rajda, Cecilia; Rejdak, Konrad; Schmidt, HK; van Pesch, Vincent; Waubant, E; Wolf, C; Hemmer, B; Deisenhammer, Florian; Giovannoni, Gavin. 2010. Short commentary on 'a consensus protocol for the standardization of cerebrospinal fluid collection and biobanking'. Multiple Sclerosis. 16: 129-132. doi: 10.1177/1352458509356368
  • Rajalahti, Tarja; Arneberg, Reidar; Berven, Frode; Myhr, Kjell-Morten; Ulvik, Rune Johan; Kvalheim, Olav Martin. 2009. Biomarker discovery in mass spectral profiles by means of selectivity ratio plot. Chemometrics and Intelligent Laboratory Systems. 95: 35-48. doi: 10.1016/j.chemolab.2008.08.004
  • Teunissen, Charlotte E.; Petzold, Andreas; Bennett, Jeffrey L.; Berven, Frode; Brundin, Lena; Comabella, Manuel; Franciotta, Diego; Frederiksen, Jette Lautrup; Fleming, John O.; Furlan, Rafaello; Hintzen, Rogier Q.; Hughes, S.G.; Johnson, Matk H.; Krasulova, Eva; Kuhle, Jens; Magnone, Maria Chiara; Rajda, Cecilia; Rejdak, Konrad; Schmidt, Hollie K.; van Pesch, Vincent; Waubant, Emmanuelle; Wolf, Claude; Giovannoni, Gavin; HemmerMd, Bernhard; Tumani, Hayrettin; Deisenhammer, Florian. 2009. A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking. Neurology. 73: 1914-1922. doi: 10.1212/WNL.0b013e3181c47cc2
  • Tumani, Hayrettin; Hartung, Hans-Peter; Hemmer, Bernhard; Teunissen, Charlotte; Deisenhammer, Florian; Giovannoni, Gavin; Zettl, Uwe; Berven, Frode; BioMS Study Group, x. 2009. Cerebrospinal fluid biomarkers in multiple sclerosis. Neurobiology of Disease. 35: 117-127. doi: 10.1016/j.nbd.2009.04.010
  • Målen, Hiwa; Berven, Frode; Søfteland, Tina; Arntzen, Magnus Øverlie; D Santos, Clive; De Souza, Gustavo Antonio; Wiker, Harald G. 2008. Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. Proteomics. 8: 1859-1870. doi: 10.1002/pmic.200700528
  • Rajalahti, Tarja; Arneberg, Reidar; Berven, Frode; Kroksveen, Ann Cathrine; Berle, Magnus Foldal; Myhr, Kjell-Morten; Vedeler, Christian A.; Ulvik, Rune Johan; Kvalheim, Olav Martin. 2008. Biomarker discovery from mass spectral profiles: A combined proteomics and multivariate analysis. European Journal of Pharmaceutical Sciences. 34: S27-S27. doi: 10.1016/j.ejps.2008.02.068
  • Rajalahti, Tarja; Arneberg, Reidar; Berven, Frode; Kroksveen, Ann Cathrine; Berle, Magnus Foldal; Myhr, Kjell-Morten; Vedeler, Christian A.; Ulvik, Rune Johan; Kvalheim, Olav Martin. 2008. Early diagnosis and biomarker discovery from mass spectral profiles: application to multiple sclerosis. Multiple Sclerosis. 14: S285-S285. doi: 10.1177/1352458508096399
  • Arneberg, Reidar; Rajalahti, Tarja; Flikka, Kristian; Berven, Frode; Kroksveen, Ann Cathrine; Berle, Magnus Foldal; Myhr, Kjell-Morten; Vedeler, Christian A.; Ulvik, Rune Johan; Kvalheim, Olav Martin. 2007. Pretreatment of mass spectral profiles: Application to proteomic data. Analytical Chemistry. 79: 7014-7026. doi: 10.1021/ac070946s
  • Berven, Frode; Kroksveen, Ann Cathrine; Berle, Magnus Foldal; Rajalahti, Tarja; Flikka, Kristian; Arneberg, Reidar; Myhr, Kjell-Morten; Vedeler, Christian A.; Kvalheim, Olav Martin; Ulvik, Rune Johan. 2007. Pre-analytical influence on the low molecular weight cerebrospinal fluid proteome. PROTEOMICS - Clinical Applications. 1: 699-711. doi: 10.1002/prca.200700126
  • Målen, Hiwa; Berven, Frode; Fladmark, Kari Espolin; Wiker, Harald G. 2007. Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics. 7: 1702-1718. doi: 10.1002/pmic.200600853
  • Aukrust, Ingvild; Evensen, Lasse; Hollås, Hanne; Berven, Frode; Atkinson, R. Andrew; Trave, Gilles Michel; Flatmark, Torgeir; Vedeler, Anni. 2006. Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation. Journal of Molecular Biology. 363: 469-481. doi: 10.1016/j.jmb.2006.08.042
  • Berven, Frode; Flikka, Kristian; Berle, Magnus Foldal; Vedeler, Christian A.; Ulvik, Rune Johan. 2006. Proteomic-based biomarker discovery with emphasis on cerebrospinal fluid and multiple sclerosis. Current Pharmaceutical Biotechnology. 7: 147-158.
  • Berven, Frode; Karlsen, Odd Andre; Straume, Anne Hege; Flikka, Kristian; Murrell, J. Collin; Fjellbirkeland, Anne; Lillehaug, Johan; Eidhammer, Ingvar; Jensen, Harald B. 2006. Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. Archives of Microbiology. 184: 362-377.
  • Karlsen, Odd Andre; Ramsevik, Linda; Bruseth, Live J.; Larsen, Øivind; Brenner, Annette Katharina; Berven, Frode; Jensen, Harald B; Lillehaug, Johan. 2005. Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). The FEBS Journal. 272: 2428-2440.
  • Berven, Frode; Flikka, Kristian; Jensen, Harald B; Eidhammer, Ingvar. 2004. BOMP: a program to predict integral beta-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria. Nucleic Acids Research. 32: W394-W399. doi: 10.1093/nar/gkh351
  • Berven, Frode; Karlsen, Odd Andre; Murrell, Colin; Jensen, Harald B. 2003. Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. Electrophoresis. 24: 757-761.
  • Karlsen, Odd Andre; Berven, Frode; Stafford, Grasham; Larsen, Øivind; Murrell, Colin; Jensen, Harald B; Fjellbirkeland, Anne. 2003. The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. Applied and Environmental Microbiology. 69: 2386-2388.
  • Hordvik, Ivar; Berven, Frode; Solem, Stein Tore; Hatten, Frode; Endresen, Curt. 2002. Analysis of two IgM isotypes in Atlantic salmon and brown trout. Molecular Immunology. 39: 313-321.
Rapporter/avhandlinger
  • Berven, Frode. 2005. Analysing the outer membrane and subproteome of Methylococcus capsulatus (Bath) using proteomics and bioinformatics. 72 sider.
  • Berven, Frode. 2001. The establishement and use of 2-dimensional gel electrophoresis in proteome studies of Methylococcus capsulatus(Bath).
Bokkapitler
  • Aasebø, Elise; Berven, Frode; Selheim, Frode; Barsnes, Harald; Vaudel, Marc. 2016. Interpretation of Quantitative Shotgun Proteomic Data. Chapter 19, sider 261-274. I:
    • Reinders, Jörg. 2016. Proteomics in Systems Biology. Springer. 313 sider. ISBN: 978-1-4939-3339-6.
  • Guldbrandsen, Astrid; Barsnes, Harald; Kroksveen, Ann Cathrine; Berven, Frode; Vaudel, Marc. 2016. A Simple Workflow for Large Scale Shotgun Glycoproteomics. Chapter 20, sider 275-286. I:
    • Reinders, Jörg. 2016. Proteomics in Systems Biology. Springer. 313 sider. ISBN: 978-1-4939-3339-6.
  • Lereim, Ragnhild Reehorst; Oveland, Eystein; Berven, Frode; Vaudel, Marc; Barsnes, Harald. 2016. Visualization, Inspection and Interpretation of Shotgun Proteomics Identification Results. Part III Bioinformatic Tools for Proteomics data Analysis, sider 227-236. I:
    • Mirzaei, Hamid; Carrasco, Martin. 2016. Modern Proteomics – Sample Preparation, Analysis and Practical Applications. Springer. 525 sider. ISBN: 978-3-319-41446-1.
  • Muth, Thilo; Rapp, Erdmann; Berven, Frode; Barsnes, Harald; Vaudel, Marc. 2016. Tandem Mass Spectrum Sequencing: An Alternative to Database Search Engines in Shotgun Proteomics. Part III Bioinformatic Tools for Proteomics data Analysis, sider 217-226. I:
    • Mirzaei, Hamid; Carrasco, Martin. 2016. Modern Proteomics – Sample Preparation, Analysis and Practical Applications. Springer. 525 sider. ISBN: 978-3-319-41446-1.
  • Verheggen, Kenneth; Martens, Lennart; Berven, Frode; Barsnes, Harald; Vaudel, Marc. 2016. Database Search Engines: Paradigms, Challenges and Solutions. Part II Mass Spectrometry for Proteomics Analysis, sider 147-156. I:
    • Mirzaei, Hamid; Carrasco, Martin. 2016. Modern Proteomics – Sample Preparation, Analysis and Practical Applications. Springer. 525 sider. ISBN: 978-3-319-41446-1.
  • Vaudel, Marc; Barsnes, Harald; Martens, Lennart; Berven, Frode. 2014. Bioinformatics for Proteomics: Opportunities at the interface between the scientists, their experiments and the community. Part VI, sider 239-248. I:
    • Martins-de-Souza, Daniel. 2014. Shotgun Proteomics. Springer. 492 sider. ISBN: 978-1-4939-0684-0.

Se fullstendig oversikt over publikasjoner i CRIStin.

1.      A    Berle M, Wester KG, Ulvik RJ, Kroksveen AC, Haaland OA, Amiry-Moghaddam M, Berven FS, Helland CA. “Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults.” Cerebrospinal fluid research,  2010 June 10;7:8.

2.      A    Rajalahti T, Kroksveen AC, Arneberg R, Berven FS, Vedeler CA, Myhr KM, Kvalheim OM. “A multivariate approach to reveal biomarker signatures for disease classification: application to mass spectral profiles of cerebrospinal fluid from patients with multiple sclerosis.” Journal of Proteome Research, 2010 July 2;9(7):3608-20.

3.      A    Berven FS. Ahmad R. Clauser K. Carr SA. “Optimizing performance of glycopeptides capture for plasma proteomics”. Journal of Proteome Research, 2010 April 5;9(4):1706-15.

4.      A    Teunissen CE, Tumani HT, Bennett JL, Berven FS, ++, Deisenhammer F, Giovannoni G. “Short commentary on 'a consensus protocol for the standardization of cerebrospinal fluid collection and biobanking'. Multiple Sclerosis, 2010; 16(2) 129-32.

5.      A    Teunissen CE, Tumani HT, JL. Bennett, FS. Berven, ++, M. Comabella, D., C. Wolf, H. Tumani, B. Hemmer, F. Deisenhammer. “A consensus protocol for standardisation of CSF sampling and biobanking”. Neurology, 2009;73;1914-1922.

6.      A    Tumani H, Hartung HP, Hemmer B, Teunissen C, Deisenhammer F, Giovannoni G, Zettl UK, Altintas A, Bennett JL, Berven FS, Petzold A, Rajda C, Rejdak K, van Pesch V, Waubant E. “Cerebrospinal fluid biomarkers in multiple sclerosis”. Neurobiol Dis. 2009 Aug;35(2):117-27.

7.      A    Rajalahti T. Arneberg R. Berven FS. Myhr KM. Ulvik RJ. Kvalheim OM. “Biomarker discovery in mass spectral profiles by means of selectivity ratio plot”. Chemometrics and Intelligent Laboratory Systems. 2008 August

8.      A    Målen, H. Berven, FS. Søfteland, T. Arntzen, ØM. D’Santos, C. Wiker, H. “Membrane- and membrane associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies”. Proteomics. 2008 may 8(9) 1859-70.

9.      A    Rajalahti, T. Arneberg, R. Berven, FS. Kroksveen, AC. Berle, M. Flikka, K. Myhr, KM. Vedeler, C. Kvalheim, OM. Ulvik, RJ. “Pretreatment of mass spectral profiles: Application to proteomic data”. Analytical Chemistry. 2007 August 79 (18) 7014-7026.

10.   A    Berven, FS. Kroksveen, AC. Berle, M. Flikka, K. Myhr, KM. Vedeler, C. Arneberg, R. Rajalahti, T. Kvalheim, OM. Ulvik, RJ. “Pre-analytical influence on the low molecular weight cerebro spinal fluid proteome”. Proteomics Clinical Applications. 2007 July 1(7) 699-711. Selected as an “In this issue” highlighted article.

11.   A    Målen, H. Berven, FS. Fladmark, K. Wiker, H. “Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv”.  Proteomics. 2007 May 7(10) 1702-18. Selected as an “In this issue” highlighted article.

12.   A    Aukrust I, Evensen L, Hollas H, Berven F, Atkinson RA, Trave G, Flatmark T, Vedeler A. “Engineering, biophysical  characterization and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation”. Journal of molecular biology. 2006 Oct 20;363(2):469-81.

13.   A    Berven FS, Flikka K, Berle M, Vedeler C, Ulvik RJ. “Proteomic-based biomarker discovery with emphasis on cerebrospinal fluid and multiple sclerosis”. Curr Pharm Biotechnol. 2006 Jun;7(3):147-58. Review.

14.   A    Berven, FS. Karlsen, OA. Straume, AH. Flikka, K. Murrell, JC. Lillehaug, JR. Fjellbirkeland, A. Eidhammer, I. Jensen, HB. ”Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools”. Arch Microbiol. 2006 Feb;184(6):362-77. Epub 2005 Nov 26.

15.   A    Karlsen, OA. Ramsevik, L. Bruseth, LJ. Larsen O. Brenner, A. Berven, FS. Jensen, HB. Lillehaug, JR. “Characterization of a prokaryotic haemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath)”. FEBS journal 2005, Volume 272, Issue10, Pages 2428-2440.

16.   A    Berven, FS. Flikka, K. Jensen, HB. Eidhammer, I. “BOMP: a program to predict integral b-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria”. Nucleic Acids Research 2004, Volume 32, Web Server Issue, Pages W394-399.

17.   A    Karlsen, OA. Berven, FS. Stafford, GP. Larsen, O. Murrell, JC. Jensen, HB. Fjellbirkeland, A. “The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium”. Applied Environmental Microbiology, April 2003, Volume 69, Issue 4, Pages 2386-2388.

18.   A    Berven, FS. Karlsen OA. Murrell, JC. Jensen, HB. “Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure”. Electrophoresis, February 2003, Volume 24, Issue 4, Pages 757-761.

 

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