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Jarl Underhaugs bilde

Jarl Underhaug

Førsteamanuensis, Manager for den norske NMR-plattformen
  • E-postJarl.Underhaug@uib.no
  • Telefon+47 55 58 34 74+47 952 16 056
  • Besøksadresse
    Realfagsbygget
    Allégaten 41
    5007 Bergen
    Rom 
    3051C
  • Postadresse
    Postboks 7803
    5020 BERGEN
Tidsskriftartikler
  • Yuste-Checa, Patricia; Brasil, Sandra; Gamez, Alejandra; Underhaug, Jarl; Desviat, Lourdes Ruiz; Ugarte, Magdalena; Pérez-Cerdá, Celia; Martinez, Aurora; Pérez, Belén. 2017. Pharmacological Chaperoning: A Potential Treatment for PMM2-CDG. Human Mutation. 38: 160-168. doi: 10.1002/humu.23138
  • Hole, Magnus; Jorge Finnigan, Ana; Underhaug, Jarl; Teigen, Knut; Martinez, Aurora. 2016. Pharmacological chaperones that protect Tetrahydrobiopterin dependent aromatic amino acid hydroxylases through different mechanisms. Current Drug Targets. 17: 1515-1526. doi: 10.2174/1389450117666160307143512
  • Hole, Magnus; Underhaug, Jarl; Diez, Hector; Ying, Ming; Røhr, Åsmund Kjendseth; Jorge-Finnigan, Ana; Fernàndez-Castillo, Noèlia; Garcia-Cazorla, Àngels; Kristoffer Andersson, K.; Teigen, Knut; Martinez, Aurora. 2016. Erratum: Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms (Biochimica et Biophysica Acta - Proteins and Proteomics (2015) 1854:9 (1078-1089) DOI: 10.1016/j.bbapap.2015.04.030). Biochimica et Biophysica Acta - Proteins and Proteomics. 1864: 317. doi: 10.1016/j.bbapap.2015.11.008
  • Aubi Catevilla, Oscar; Flydal, Marte Innselset; Zheng, Huaixin; Skjærven, Lars; Rekand, Illimar; Leiros, Hanna-Kirsti S.; Haug, Bengt Erik; Cianciotto, Nicholas P.; Martinez, Aurora; Underhaug, Jarl. 2015. Discovery of a Specific Inhibitor of Pyomelanin Synthesis in Legionella pneumophila. Journal of Medicinal Chemistry. 58: 8402-8412. doi: 10.1021/acs.jmedchem.5b01589
  • Hole, Magnus; Underhaug, Jarl; Diez, Hector; Ying, Ming; Røhr, Åsmund Kjendseth; Jorge Finnigan, Ana; Fernàndez-Castillo, Noèlia; García-Cazorla, Angels; Andersson, K. Kristoffer; Teigen, Knut; Martinez, Aurora. 2015. Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms. Biochimica et Biophysica Acta - Proteins and Proteomics. 1854: 1078-1089. doi: 10.1016/j.bbapap.2015.04.030
  • Koldsø, Heidi; Andersen, Ole Juul; Nikolajsen, Camilla Lund; Scavenius, Carsten; Sørensen, Charlotte S.; Underhaug, Jarl; Runager, Kasper; Nielsen, Niels Chr.; Enghild, Jan J.; Schiøtt, Birgit. 2015. Early Events in the Amyloid Formation of the A546T Mutant of Transforming Growth Factor β‑Induced Protein in Corneal Dystrophies Compared to the Nonfibrillating R555W and R555Q Mutants. Biochemistry. 54: 5546-5556. doi: 10.1021/acs.biochem.5b00473
  • Wettstein, Sara; Underhaug, Jarl; Perez, Belen; Marsden, Brian D.; Yue, Wyatt W.; Martinez, Aurora; Blau, Nenad. 2015. Linking genotypes database with locus-specific database and genotype-phenotype correlation in phenylketonuria. European Journal of Human Genetics. 23: 302-309. doi: 10.1038/ejhg.2014.114
  • Jorge Finnigan, Ana; Brasil, Sandra; Underhaug, Jarl; Ruiz-Sala, Pedro; Amerinero, Begoña; Banerjee, Ruma; Desviat, Lourdes R.; Ugarte, Magdalena; Martinez, Aurora; Pérez, Belén. 2013. Pharmacological chaperones as a potential therapeutic option in methylmalonic aciduria cblB type. Human Molecular Genetics. 22: 3680-3689. doi: 10.1093/hmg/ddt217
  • Martin, Ianire; Underhaug, Jarl; Celaya, Garbiñe; Moro, Fernando; Teigen, Knut; Martinez, Aurora; Muga, Arturo. 2013. Screening and evaluation of small organic molecules as ClpB inhibitors and potential antimicrobials. Journal of Medicinal Chemistry. 56: 7177-7189. doi: 10.1021/jm400499k
  • Underhaug, Jarl; Koldsø, Heidi; Runager, Kasper; Nielsen, Jakob Toudahl; Sørensen, Charlotte S; Kristensen, Torsten; Otzen, Daniel Erik; Karring, Henrik; Malmendal, Anders; Schiøtt, Birgit; Enghild, Jan J; Nielsen, Niels Chr. 2013. Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization. Biochimica et Biophysica Acta - Proteins and Proteomics. 1834: 2812-2822. doi: 10.1016/j.bbapap.2013.10.008
  • Bustad, Helene J.; Skjærven, Lars; Ying, Ming; Halskau jr, Øyvind; Baumann, Anne; Rodriguez-Larrea, David; Costas, Miguel; Underhaug, Jarl; Sanchez-Ruiz, Jose Manuel; Martinez, Aurora. 2012. The peripheral binding of 14-3-3gamma to membranes involves isoform-specific histidine residues. PLoS ONE. 7. doi: 10.1371/journal.pone.0049671
  • Havukainen, Heli; Underhaug, Jarl; Wolschin, Florian; Amdam, Gro Vang; Halskau jr, Øyvind. 2012. A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. Journal of Experimental Biology. 215: 1837-1846. doi: 10.1242/jeb.065623
  • Kulminskaya, Natalia V.; Pedersen, Marie Ø.; Bjerring, Morten; Underhaug, Jarl; Miller, Mette; Frigaard, Niels-Ulrik; Nielsen, Jakob T.; Nielsen, Niels Chr. 2012. In situ solid-state NMR spectroscopy of protein in heterogeneous membranes: the baseplate antenna complex of chlorobaculum tepidum. Angewandte Chemie International Edition. 51: 6891-6895. doi: 10.1002/anie.201201160
  • Underhaug, Jarl; Aubi, Oscar; Martinez, Aurora. 2012. Phenylalanine hydroxylase misfolding and pharmacological chaperones. Current Topics in Medicinal Chemistry. 12: 2534-2545. doi: 10.2174/1568026611212220008
  • Johannessen, Helene Bustad; Underhaug, Jarl; Halskau jr, Øyvind; Martinez, Aurora. 2011. The binding of 14-3-3 gamma to membranes studied by intrinsic fluorescence spectroscopy. FEBS Letters. 585: 1163-1168. doi: 10.1016/j.febslet.2011.03.027
  • Bustad, Helene J.; Rønneseth, Eva; Toska, Karen; Underhaug, Jarl; Martinez, Aurora; Sandberg, Sverre. 2010. Characterization of the molecular basis of acute intermittent porphyria. The FEBS Journal. 277: 76-76.
  • Johannessen, Helene Bustad; Rxnneseth, E; Underhaug, Jarl; Skjærven, Lars; Toska, Karen; Martinez, Aurora; Sandberg, Sverre. 2010. CHARACTERIZATION OF THE MOLECULAR BASIS OF ACUTE INTERMITTENT PORPHYRIA. Journal of Inherited Metabolic Disease. 33: S177-S177.
  • Jorge-Finnigan, A; Underhaug, Jarl; Desviat, Lourdes R.; Martinez, Aurora; Ugarte, Magdalena; Perez, Belen. 2010. POTENTIAL PHARMACOLOGYCAL CHAPERONE THERAPY FOR ISOLATED METHYLMALONIC ACIDURIA cbIB TYPE. Journal of Inherited Metabolic Disease. 33: S40-S40.
  • Halskau jr, Øyvind; Perez-Jimenez, Raul; Ibarra-Molero, Beatriz; Underhaug, Jarl; Muñoz, Victor; Martinez, Aurora; Sanchez-Ruiz, Jose Manuel. 2008. Large-scale modulation of thermodynamic protein folding barriers linked to electrostatics. Proceedings of the National Academy of Sciences of the United States of America. 105: 8625-8630. doi: 10.1073/pnas.0709881105
  • Halskau, Øyvind; Underhaug, Jarl; Frøystein, Nils Åge; Martinez, Aurora. 2005. Conformational flexibility of alpha-lactalbumin related to its membrane binding capacity. Journal of Molecular Biology. 349: 1072-1086. doi: 10.1016/j.jmb.2005.04.020

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