Hjem
Tomas Mikal Eagans bilde

Tomas Mikal Eagan

Professor
  • E-postTomas.Eagan@uib.no
  • Besøksadresse
    3 etg Sentralblokken, Lungefløyen
    Jonas Lies vei 65
    5021 Bergen
    Rom 
    3077
  • Postadresse
    Postboks 7804
    5020 Bergen

Medisinstudenter ved Universitet i Bergen i andre og fjerde termin av Indremedisin.

  • Aardal, Marit Elisabeth; Svendsen, Lene; Lehmann, Sverre; Eagan, Tomas Mikal; Haaland, Ingvild. 2017. A pilot study of hot-wire, ultrasonic and wedge-bellows spirometer inter- and intra-variability. BMC Research Notes. 10. doi: 10.1186/s13104-017-2825-0
  • Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L.; Dellacà, Raffaele; Eagan, Tomas Mikal; Bakke, Per S.; Hardie, Jon Andrew. 2017. The association of tidal EFL with exercise performance, exacerbations, and death in COPD. The International Journal of Chronic Obstructive Pulmonary Disease. 12: 2179-2188. doi: 10.2147/COPD.S138720
  • Tangedal, Solveig; Aanerud, Marianne; Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Bakke, Per S.; Eagan, Tomas Mikal. 2017. Comparing microbiota profiles in induced and spontaneous sputum samples in COPD patients. Respiratory Research. 18:164: 1-9. doi: 10.1186/s12931-017-0645-3
  • Eagan, Tomas Mikal; Hardie, Jon Andrew; Jul-Larsen, Åsne; Grydeland, Thomas Blix; Bakke, Per S.; Cox, Rebecca Jane. 2016. Self-reported influenza vaccination and protective serum antibody titers in a cohort of COPD patients. Respiratory Medicine. 115: 53-59. doi: 10.1016/j.rmed.2016.04.008
  • Erdal, Marta; Johannessen, Ane; Eagan, Tomas Mikal; Bakke, Per S.; Gulsvik, Amund; Grønseth, Rune. 2016. Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients. The International Journal of Chronic Obstructive Pulmonary Disease. 11: 2099-2108. doi: 10.2147/COPD.S108720
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2016. Respiratory timing and dynamic hyperinflation during incremental exercise in patients with COPD. European Respiratory Journal. 48. doi: DOI: 10.1183/13993003.congress-2016.PA1584
  • Husebø, Gunnar; Bakke, Per S.; Grønseth, Rune; Hardie, Jon Andrew; Ueland, Thor; Aukrust, Pål; Eagan, Tomas Mikal. 2016. Macrophage migration inhibitory factor, a role in COPD. American Journal of Physiology - Lung cellular and Molecular Physiology. 311: L1-L7. doi: 10.1152/ajplung.00461.2015
  • Jonassen, Trygve Muller; Eagan, Tomas Mikal; Bjorvatn, Bjørn; Lehmann, Sverre. 2016. Associations between obstructive lung disease and symptoms of obstructive sleep apnoea in a general population. Clinical Respiratory Journal. doi: 10.1111/crj.12472
  • Leiten, Elise Orvedal; Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Bakke, Per S.; Grønseth, Rune. 2016. Complications and discomfort of bronchoscopy: a systematic review. European Clinical Respiratory Journal. 3. 9 sider. Publisert 2016-11-11. doi: 10.3402/ecrj.v3.33324
  • Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Bakke, Per S.; Eagan, Tomas Mikal; Grønseth, Rune. 2016. Participation in research bronchoscopy: a literature review. European Clinical Respiratory Journal.
  • Roth, Kjetil; Eagan, Tomas Mikal; Hardie, Jon Andrew. 2016. Expert opinion of mediastinal lymph node positions from an intrabronchial view. BMC Pulmonary Medicine. 16. doi: 10.1186/s12890-016-0176-6
  • Saure, Eirunn Waatevik; Bakke, Per S.; Eagan, Tomas Mikal; Aanerud, Marianne; Jensen, Robert Leroy; Grydeland, Thomas Blix; Johannessen, Ane; Nilsen, Roy Miodini; Thorsen, Einar; Hardie, Jon Andrew. 2016. Diffusion capacity and CT measures of emphysema and airway wall thickness – relation to arterial oxygen tension in COPD patients. European Clinical Respiratory Journal. 3. doi: 10.3402/ecrj.v3.29141
  • Storebø, Michael Langballe; Eagan, Tomas Mikal; Eide, Geir Egil; Gulsvik, Amund; Thorsen, Einar; Bakke, Per S. 2016. Change in Pulmonary Diffusion Capacity in a General Population Sample over 9 Years. European Clinical Respiratory Journal. 3. 9 sider. doi: 10.3402%2Fecrj.v3.31265
  • Wåtevik, Marie Johanne; Johannessen, Ane; Gomez Real, Francisco; Aanerud, Marianne; Hardie, Jon Andrew; Bakke, Per S.; Eagan, Tomas Mikal. 2016. Oxygen desaturation in 6-min walk test is a risk factor for adverse outcomes in COPD patients. European Respiratory Journal. 48: 82-91. doi: 10.1183/13993003.00975-2015
  • Aanerud, Marianne; Saure, Eirunn Waatevik; Benet, Marta; Basagana, Xavier; Bakke, Per S.; Garcia-Aymerich, Judith; Eagan, Tomas Mikal; Anto, Josep Maria; Hardie, Jon Andrew. 2015. Serial measurements of arterial oxygen tension are associated with mortality in COPD. COPD: Journal of Chronic Obstructive Pulmonary Disease. 12: 287-294. doi: 10.3109/15412555.2014.948996
  • Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L.; Eagan, Tomas Mikal; Bakke, Per S.; Hardie, Jon Andrew. 2015. Variability of within-breath reactance in COPD patients and its association with dyspnoea. European Respiratory Journal. 45: 625-634. doi: 10.1183/09031936.00051214
  • Frisk, Bente; Hardie, Jon Andrew; Espehaug, Birgitte; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2015. Peak oxygen uptake and breathing pattern in COPD patients - a four-year longitudinal study. BMC Pulmonary Medicine. 15:93. doi: 10.1186/s12890-015-0095-y
  • Persson, Louise Jeanette Pauline; Aanerud, Marianne; Hiemstra, Pieter Sicco; Michelsen, Annika; Ueland, Thor; Hardie, Jon Andrew; Aukrust, Pål; Bakke, Per S.; Eagan, Tomas Mikal. 2015. Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD. PLoS ONE. 10:e0121622. doi: 10.1371/journal.pone.0121622
  • Erdal, Marta; Johannessen, Ane; Askildsen, Jan Erik; Eagan, Tomas Mikal; Gulsvik, Amund; Grønseth, Rune. 2014. Productivity losses in chronic obstructive pulmonary disease: a population-based survey. BMJ Open Respiratory Research. 1: 1-8.
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients. Physiological Reports. 2. doi: 10.1002/phy2.222
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Physical activity and longitudinal change in 6-min walk distance in COPD patients. Respiratory Medicine. 108: 86-94. doi: 10.1016/j.rmed.2013.09.004
  • Husebø, Gunnar Reksten; Bakke, Per S.; Aanerud, Marianne; Hardie, Jon Andrew; Ueland, Thor; Grønseth, Rune; Persson, Louise Jeanette Pauline; Aukrust, Pål; Eagan, Tomas Mikal. 2014. Predictors of exacerbations in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study. PLoS ONE. 9:e0109721. doi: 10.1371/journal.pone.0109721
  • Olfert, I. Mark; Malek, Moh H.; Eagan, Tomas Mikal; Wagner, Harrieth; Wagner, Peter D. 2014. Inflammatory cytokine response to exercise in alpha-1-antitrypsin deficient COPD patients 'on' or 'off' augmentation therapy. BMC Pulmonary Medicine. 14:106. doi: 10.1186/1471-2466-14-106
  • Qvale, Tor Hatlestad; Storstein, Anette; Mazengia, Kibret Yimer; Eagan, Tomas Mikal; Bakke, Per S.; Vedeler, Christian A. 2014. Paraneoplastic Hu and CRMP5 antibodies are present in smokers without cancer or neurological disease. Respirology (Carlton South. Print). 19: 730-734. doi: 10.1111/resp.12292
  • Saure, Eirunn Waatevik; Eagan, Tomas Mikal; Jensen, Robert Leroy; Bakke, Per S.; Johannessen, Ane; Aanerud, Marianne; Nilsen, Roy Miodini; Thorsen, Einar; Hardie, Jon Andrew. 2014. Predictors for PaO2 and hypoxemic respiratory failure in COPD-A three-year follow-up. COPD: Journal of Chronic Obstructive Pulmonary Disease. 11: 531-538. doi: 10.3109/15412555.2014.898027
  • Tangedal, Solveig; Aanerud, Marianne; Persson, Louise Jeanette Pauline; Brokstad, Karl Albert; Bakke, Per S.; Eagan, Tomas Mikal. 2014. Comparison of inflammatory markers in induced and spontaneous sputum in a cohort of COPD patients. Respiratory Research. 15. doi: 10.1186/s12931-014-0138-6
  • Aanerud, Marianne; Braut, Harald; Wentzel-Larsen, Tore; Eagan, Tomas Mikal; Bakke, Per S. 2013. Non-response in telephone surveys of COPD patients does not introduce bias. Journal of Telemedicine and Telecare. 19: 40-44. doi: 10.1177/1357633X12474960
  • Aarli, Bernt Bøgvald; Eagan, Tomas Mikal; Ellingsen, Ivar; Bakke, Per S.; Hardie, Jon Andrew. 2013. Reference values for within-breath pulmonary impedance parameters in asymptomatic elderly. Clinical Respiratory Journal. 7: 245-252. doi: 10.1111/j.1752-699X.2012.00312.x
  • Hynninen, Kia Minna; Pallesen, Ståle; Hardie, Jon Andrew; Eagan, Tomas Mikal; Bjorvatn, Bjørn; Bakke, Per S.; Nordhus, Inger Hilde. 2013. Insomnia symptoms, objectively measured sleep, and disease severity in chronic obstructive pulmonary disease outpatients. Sleep Medicine. 14: 1328-1333. doi: 10.1016/j.sleep.2013.08.785
  • Johannessen, Ane; Nilsen, Roy Miodini; Storebø, Michael Langballe; Gulsvik, Amund; Eagan, Tomas Mikal; Bakke, Per S. 2013. Comparison of 2011 and 2007 global initiative for chronic obstructive lung disease guidelines for predicting mortality and hospitalization. American Journal of Respiratory and Critical Care Medicine. 188: 51-59. doi: 10.1164/rccm.201212-2276OC
  • Bakke, Per S.; Rönmark, Eva; Eagan, Tomas Mikal; Pistelli, Francesco; Annesi-Maesano, Isabella; Maly, Marek; Meren, Mari; Zielinski, Jan; Viegi, Giovanni; Lundbäck, Bo. 2012. Recommendations for epidemiological studies on COPD. European Respiratory Journal. 39: 1278-1279. doi: 10.1183/09031936.00011712
  • Eagan, Tomas Mikal; Gabazza, Esteban C.; D'Alessandro-Gabazza, Corina; Gil-Bernabe, Paloma; Aoki, Shinya; Hardie, Jon Andrew; Bakke, Per S.; Wagner, Peter D. 2012. TNF-alpha is associated with loss of lean body mass only in already cachectic COPD patients. Respiratory Research. 13. 10 sider. doi: 10.1186/1465-9921-13-48
  • Gjerde, Bjarte; Bakke, Per S.; Ueland, Thor; Hardie, Jon Andrew; Eagan, Tomas Mikal. 2012. The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway. Respiratory Medicine. 106: 361-366. doi: 10.1016/j.rmed.2011.10.004
  • Johannessen, Ane; Bakke, Per S.; Hardie, Jon Andrew; Eagan, Tomas Mikal. 2012. Association of exposure to environmental tobacco smoke in childhood with chronic obstructive pulmonary disease and respiratory symptoms in adults. Respirology (Carlton South. Print). 17: 499-505. doi: 10.1111/j.1440-1843.2012.02129.x
  • Jonassen, Trygve Muller; Eagan, Tomas Mikal; Lehmann, Sverre. 2012. Daytime respiratory symptoms are associated with obstructive sleep apnoea syndrome. Journal of Sleep Research. 21: 229-230.
  • Persson, Louise; Aanerud, Marianne; Hiemstra, Pieter Sicco; Hardie, Jon Andrew; Bakke, Per S.; Eagan, Tomas Mikal. 2012. Chronic obstructive pulmonary disease is associated with low levels of vitamin D. PLoS ONE. 7. 8 sider. doi: 10.1371/journal.pone.0038934
  • Qvale, Tor H.; Storstein, Anette; Mazengia, Kibret Yimer; Eagan, Tomas Mikal; Bakke, Per S.; Vedeler, Christian A. 2012. Hu antibodies are present in smokers with chronic obstructive pulmonary disease without cancer or neurological disease. Journal of Neuroimmunology. 253: 21-22.
  • Saure, Eirunn Waatevik; Eagan, Tomas Mikal; Jensen, Robert Leroy; Aanerud, Marianne; Aukrust, Pål; Bakke, Per S.; Hardie, Jon Andrew. 2012. Explained variance for blood gases in a population with COPD. Clinical Respiratory Journal. 6: 72-80. doi: 10.1111/j.1752-699X.2011.00248.x
  • Waatevik, Marie Johanne; Johannessen, Ane; Hardie, Jon Andrew; Bjordal, Jan Magnus; Aukrust, Pål; Bakke, Per S.; Eagan, Tomas Mikal. 2012. Different COPD disease characteristics are related to different outcomes in the 6-minute walk test. COPD: Journal of Chronic Obstructive Pulmonary Disease. 9: 227-234. doi: 10.3109/15412555.2011.650240
  • Bakke, Per S.; Rönmark, Eva; Eagan, Tomas Mikal; Pistelli, Francesco; Annesi-Maesano, Isabella; Maly, Marek; Meren, Mari; Vermeire, Pat; Vestbo, Jørgen; Viegi, Giovanni; Zielinski, Jennifer; Lundbäck, Bo. 2011. Recommendations for epidemiological studies on COPD. European Respiratory Journal. 38: 1261-1277. doi: 10.1183/09031936.00193809
  • Edvardsen, Anne; Akerø, Aina; Hardie, Jon Andrew; Ryg, Morten; Eagan, Tomas Mikal; Skjønsberg, Ole Henning; Bakke, Per S. 2011. High prevalence of respiratory symptoms during air travel in patients with COPD. Respiratory Medicine. 105: 50-56. doi: 10.1016/j.rmed.2010.10.006
  • Fasmer, Ole Bernt; Halmøy, Anne; Eagan, Tomas Mikal; Ødegaard, Ketil Joachim; Haavik, Jan. 2011. Adult attention deficit hyperactivity disorder is associated with asthma. BMC Psychiatry. 11. 7 sider. doi: 10.1186/1471-244X-11-128
  • Fasmer, Ole Bernt; Riise, Trond; Eagan, Tomas Mikal; Lund, Anders; Dilsaver, Stephen C.; Hundal, Øivind; Ødegaard, Ketil Joachim. 2011. Comorbidity of Asthma With ADHD. Journal of Attention Disorders. 15: 564-571. doi: 10.1177/1087054710372493
  • Roth, Kjetil; Eagan, Tomas Mikal; Andreassen, Alf Henrik; Leh, Friedemann; Hardie, Jon Andrew. 2011. A randomised trial of endobronchial ultrasound guided sampling in peripheral lung lesions. Lung Cancer. 74: 219-225. doi: 10.1016/j.lungcan.2011.02.013
  • Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S.; Damås, Jan Kristian; Skorge, Trude Duelien; Hardie, Jon Andrew; Ueland, Thor; Mollnes, Tom Eirik. 2010. Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. Respiratory Medicine. 104: 283-290. doi: 10.1016/j.rmed.2009.09.015
  • Eagan, Tomas Mikal Lind; Aukrust, Pål; Ueland, Thor; Hardie, Jon Andrew; Johannessen, Ane; Mollnes, Tom Eirik; Damås, Jan Kristian; Bakke, Per S.; Wagner, P.D. 2010. Body composition and plasma levels of inflammatory biomarkers in COPD. European Respiratory Journal. 36: 1027-1033. doi: 10.1183/09031936.00194209
  • Eagan, Tomas Mikal Lind; Damås, Jan Kristian; Ueland, Thor; Voll-Aanerud, Marianne; Mollnes, Tom Eirik; Hardie, Jon Andrew; Bakke, Per S.; Aukrust, Pål. 2010. Neutrophil Gelatinase-Associated Lipocalin A Biomarker in COPD. Chest. 138: 888-895. doi: 10.1378/chest.09-2718
  • Eagan, Tomas Mikal Lind; Ueland, Thor; Wagner, Peter D.; Hardie, Jon Andrew; Mollnes, Tom Eirik; Damås, Jan Kristian; Aukrust, Pål; Bakke, Per S. 2010. Systemic inflammatory markers in chronic obstructive pulmonary disease – results from the Bergen COPD Cohort Study. European Respiratory Journal. 35: 540-548. doi: 10.1183/09031936.00088209
  • Grydeland, Thomas; Dirksen, Asger; Coxson, Harvey O.; Eagan, Tomas Mikal Lind; Thorsen, Einar; Pillai, Sreekumar G.; Sharma, Sanjay; Eide, Geir Egil; Gulsvik, Amund; Bakke, Per S. 2010. Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms. American Journal of Respiratory and Critical Care Medicine. 181: 353-359. doi: 10.1164/rccm.200907-1008OC
  • Johannessen, Ane; Eagan, Tomas Mikal Lind; Omenaas, Ernst; Bakke, Per S.; Gulsvik, Amund. 2010. Socioeconomic risk factors for lung function decline in a general population. European Respiratory Journal. 36: 480-487. doi: 10.1183/09031936.00186509
  • Roth, Kjetil; Eagan, Tomas Mikal; Hardie, Jon Andrew. 2010. Significance of endobronchial lesion appearance in the diagnostic value of different endoscopic techniques Response. Respiratory Medicine. 104: 1387-1387. doi: 10.1016/j.rmed.2010.04.020
  • Voll-Aanerud, Marianne; Eagan, Tomas Mikal Lind; Plana, Estel; Omenaas, Ernst; Bakke, Per S.; Svanes, Cecilie; Siroux, Valérie; Pin, Isabelle; Anto, Josep Maria; Leynaert, Bénédicte. 2010. Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey. Health and Quality of Life Outcomes. 8. doi: 10.1186/1477-7525-8-107
  • Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S.; Damås, Jan Kristian; Skorge, Trude Duelien; Hardie, Jon Andrew; Ueland, Thor; Mollnes, Tom Eirik. 2009. Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. Respiratory Medicine. 104: 283-290. doi: 10.1016/j.rmed.2009.09.015
  • Grydeland, Thomas; Dirksen, Asger; Coxson, Harvey O.; Eagan, Tomas Mikal Lind; Thorsen, Einar; Pillai, Sreekumar G.; Sharma, S.; Eide, Geir Egil; Gulsvik, Amund; Bakke, Per S. 2009. Quantitative CT Measures of Emphysema and Airway Wall Thickness Are Related to Respiratory Symptoms. American Journal of Respiratory and Critical Care Medicine. Publisert 2009-11-19.
  • Roth, Kjetil; Hardie, Jon Andrew; Andreassen, Alf Henrik; Leh, Friedemann; Eagan, Tomas Mikal Lind. 2009. Cost minimization analysis for combinations of sampling techniques in bronchoscopy of endobronchial lesions. Respiratory Medicine. 103: 888-894. doi: 10.1016/j.rmed.2008.12.012
  • Skorge, Trude Duelien; Eagan, Tomas Mikal Lind; Eide, Geir Egil; Gulsvik, Amund; Bakke, Per S. 2009. Occupational exposure and incidence of respiratory disorders in a general population. Scandinavian Journal of Work, Environment and Health. 35: 454-460.
  • Roth, Kjetil; Hardie, Jon Andrew; Andreassen, Alf Henrik; Leh, Friedemann; Eagan, Tomas Mikal Lind. 2008. Predictors of diagnostic yield in bronchoscopy: a retrospective cohort study comparing different combinations of sampling techniques. BMC Pulmonary Medicine. 8. Publisert 2008-01-26.
  • Voll-Aanerud, Marianne; Eagan, Tomas Mikal Lind; Wentzel-Larsen, Tore; Gulsvik, Amund; Bakke, Per S. 2008. Respiratory symptoms, COPD severity, and health related quality of life in a general population sample. Respiratory Medicine. 102: 399-406. doi: 10.1016/j.rmed.2007.10.012
  • Aanerud, Marianne; Eagan, Tomas Mikal Lind; Wentzel-Larsen, Tore; Gulsvik, Amund; Bakke, Per S. 2007. Changes in Respiratory Symptoms and Health-Related Quality of Life. Chest. 131: 1890-1897. doi: 10.1378/chest.06-2629

Se fullstendig oversikt over publikasjoner i CRIStin.

 1.      Eagan, T. M., Bakke, P. S., Eide, G. E. & Gulsvik, A. Incidence of asthma and respiratory symptoms by sex, age and smoking in a community study. Eur Respir J19, 599-605 (2002).

2.      Eagan, T., Eide, G., Gulsvik, A. & Bakke, P. Nonresponse in a community cohort study. Predictors and consequences for exposure-disease associations. J Clin Epidemiol 55, 775-781 (2002).

3.      Eagan, T. M., Gulsvik, A., Eide, G. E. & Bakke, P. S. Occupational airborne exposure and the incidence of respiratory symptoms and asthma. Am J Respir Crit Care Med 166, 933-938 (2002).

4.      Eagan, T. M., Gulsvik, A., Eide, G. E. & Bakke, P. S. Remission of respiratory symptoms by smoking and occupational exposure in a cohort study. Eur Respir J 23, 589-594 (2004).

5.      Eagan, T. M., Gulsvik, A., Eide, G. E. & Bakke, P. S. The effect of educational level on the incidence of asthma and respiratory symptoms. Respir Med 98, 730-736 (2004).

6.      Brøgger, J., Eagan, T., Eide, G. E., Bakke, P. & Gulsvik, A. Bias in retrospective studies of trends in asthma incidence. Eur Respir J 23, 281-286 (2004).

7.      Skorge, T. D., Eagan, T. M., Eide, G. E., Gulsvik, A. & Bakke, P. S. The Adult Incidence of Asthma and Respiratory Symptoms by Passive Smoking in Utero or Childhood. Am J Respir Crit Care Med (2005).

8.      Eagan, T. M., Brogger, J. C., Eide, G. E. & Bakke, P. S. The incidence of adult asthma: a review. Int J Tuberc Lung Dis 9, 603-612 (2005).

9.      Skorge, T. D., Eagan, T. M., Eide, G. E., Gulsvik, A. & Bakke, P. S. Indoor exposures and respiratory symptoms in a Norwegian community sample. Thorax 60, 937-942 (2005).

10.    Eagan, T. M., Hetland, J. & Aaro, L. E. Decline in respiratory symptoms in service workers five months after a public smoking ban. Tob Control 15, 242-246 (2006).

11.    Skorge, T. D., Eagan, T. M., Eide, G. E., Gulsvik, A. & Bakke, P. S. Exposure to environmental tobacco smoke in a general population. Respir Med 101, 277-285 (2007).

12.    Voll-Aanerud, M., Eagan, T. M., Wentzel-Larsen, T., Gulsvik, A. & Bakke, P. S. Changes in respiratory symptoms and health-related quality of life. Chest 131, 1890-1897 (2007).

13.    Roth, K., Hardie, J. A., Andreassen, A. H., Leh, F. & Eagan, T. M. Predictors of diagnostic yield in bronchoscopy: a retrospective cohort study comparing different combinations of sampling techniques. BMC Pulm Med 8, 2 (2008).

14.    Voll-Aanerud, M., Eagan, T. M., Wentzel-Larsen, T., Gulsvik, A. & Bakke, P. S. Respiratory symptoms, COPD severity, and health related quality of life in a general population sample. Respir Med 102, 399-406 (2008).

15.    Roth, K., Hardie, J. A., Andreassen, A. H., Leh, F. & Lind Eagan, T. M. Cost minimization analysis for combinations of sampling techniques in bronchoscopy of endobronchial lesions. Respir Med 103, 888-894 (2009).

16.    Skorge, T. D., Eagan, T. M., Eide, G. E., Gulsvik, A. & Bakke, P. S. Occupational exposure and incidence of respiratory disorders in a general population. Scand J Work Environ Health 35, 454-461 (2009).

17.    Eagan, T. M. et al. Systemic inflammatory markers in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study. Eur Respir J 35, 540-548 (2010).

18.    Voll-Aanerud, M. et al. Respiratory symptoms in adults are related to impaired Quality of Life, regardless of asthma and COPD. Results from the European Community Respiratory Health Survey. Health and Quality of Life Outcomes 8, 107 (2010).

19.    Grydeland, T. B. et al. Quantitative computed tomography measures of emphysema and airway wall thickness are related to respiratory symptoms. Am J Respir Crit Care Med 181, 353-359 (2010).

20.    Fasmer, O. B. et al. Comorbidity of Asthma With ADHD. J Atten Disord (2010).

21.    Eagan, T. M. et al. Neutrophil Gelatinase Associated Lipocalin - a biomarker in Chronic Obstructive Pulmonary Disease. Chest 138, 888-895 (2010).

22.    Eagan, T. M. et al. Body composition and plasma levels of inflammatory biomarkers in COPD. Eur Respir J 36, 1027-1033 (2010).

23.    Johannessen, A., Eagan, T. M., Omenaas, E. R., Bakke, P. S. & Gulsvik, A. Socioeconomic risk factors for lung function decline in a general population. Eur Respir J 36, 480-487 (2010).

24.    Roth, K., Eagan, T. M., Andreassen, A. H., Leh, F. & Hardie, J. A. A randomised trial of endobronchial ultrasound guided sampling in peripheral lung lesions. Lung Cancer (2011).

25.    Saure, E. W. et al. Explained variance for blood gases in a population with COPD. Clin Respir J (2011).

26.    Fasmer, O. B., Halmoy, A., Eagan, T. M., Oedegaard, K. J. & Haavik, J. Adult attention deficit hyperactivity disorder is associated with asthma. BMC Psychiatry 11, 128 (2011).

27.    Bakke, P. S. et al. Recommendations for epidemiological studies on COPD. Eur Respir J 38, 1261-1277 (2011).

28.    Edvardsen, A. et al. High prevalence of respiratory symptoms during air travel in patients with COPD. Respir Med 105, 50-56 (2011).

29.    Gjerde, B., Bakke, P. S., Ueland, T., Hardie, J. A. & Eagan, T. M. The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway. Respir Med (2011).

30.    Persson, L. P. J. et al. Chronic obstructive pulmonary disease is associated with low levels of vitamin D. PLoS One 7, :338934 (2012).

31.    Johannessen, A., Bakke, P. S., Hardie, J. A. & Eagan, T. M. Association of exposure to environmental tobacco smoke in childhood with chronic obstructive pulmonary disease and respiratory symptoms in adults. Respirology 17, 499-505 (2012).

32.    Aarli, B. B., Eagan, T. M., Ellingsen, I., Bakke, P. S. & Hardie, J. A. Reference values for within-breath pulmonary impedance parameters in asymptomatic elderly. Clin Respir J (2012).

33.    Waatevik, M. et al. Different COPD disease characteristics are related to different outcomes in the 6-minute walk test. COPD 9, 227-234 (2012).

34.    Eagan, T. M. et al. TNF-alpha is associated with loss of lean body mass only in already cachectic COPD patients. Respir Res 13, 48 (2012).

35.    Johannessen, A. et al. Comparison of 2011 and 2007 GOLD Guidelines for Predicting Mortality and Hospitalization. Am J Respir Crit Care Med (2013).

36.    Hynninen, M. J. et al. Insomnia symptoms, objectively measured sleep, and disease severity in chronic obstructive pulmonary disease outpatients. Sleep Med 14, 1328-1333 (2013).

37.    Aanerud, M., Braut, H., Wentzel-Larsen, T., Eagan, T. M. & Bakke, P. S. Non-response in telephone surveys of COPD patients does not introduce bias. J Telemed Telecare (2013).

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The Bergen COPD Microbiome Study (MikroKOLS)

The study aims to characterize the airways microbiome in patients with COPD, compared with healthy adults.

Secondary motives are to assess different bronchoscopic sampling techniques, to compare the microbiome within the lungs (upper versus lower airways, left versus right lung), and to study the impact of tobacco smoking and mody composition on the airways microbiome.

The pilot study was performed spring of 2012, data collection is well underway, and will be finalized by Summer of 2015.

Metagenomic sequencing is performed on the Illumina MiSeq platform.  

 

The lung microbiome in interstitial lung disease Study (MikroILS)

This is an extension of the MikroKOLS study, where we aim to characterize the airways microbiome in patients undergoing evaluation for interstitial lung diseases. The first patient was included in December 2014, planned project period is until end of 2016.

The Bergen GeneCOPD follow-up study (GenKOLS oppfølgingen)

The first Bergen GeneCOPD study was performed in 2002/04, where 500 COPD patients and healthy controls were assessed with a CT scan, lung function testing and clinical data, and genewide assosiation studies were performed. In 2014 the follow-up started, aiming to include 250 patients and 400 controls. Primaty study question is the assessment of longitudinal change in COPD assessed by CT thorax, secondary motive is to assess risk factors for comorbid coronary heart disease. 

The Bergen COPD Cohort Study (BergenKOLS)

The study started in 2006, and ended in 2014. More than 400 COPD patients and 300 healthy controls were included, and most were attempted followed until the end of 2014, with annual clinical examinations.

The main research question was to search for predictors of later advers outcomes such as mortality, exacerbation frequency, development of cachexia and lung function decline. Several papers are already published, and several more are underway.