Title: Post doctor
Phone: +47 55 58 44 00
E-mail: Jerome.Ruzzin@bio.uib.no
Visiting address: 3. etasje Høyteknologisenteret, Bioblokka, Thormøhlensgate 55, 5008 Bergen
Room number: Rom 325C1/326C1
Environmental toxicology, insulin resistance syndrome, type 2 diabetes, obesity, nutrition, and public health
2011- : Post Doctoral researcher 2 (PI).
Environmental toxicology, Department of Biology, University of Bergen, Bergen, Norway.
2008-2011: Post Doctoral researcher 1 (PI).
National Institute of Nutrition and Seafood Research, Bergen, Norway.
2006-2007: Post-doctoral fellow.
University Hospital Research Center, and Institute of Nutraceuticals and Fonctional
Foods, Quebec, Canada (Supervisor: Pr. A. Marette).
2001-2005: Doctor Scientiarum.
Department of Physiology, National Institute of Occupational Health and University
of Sports, Oslo, Norway.
“Cellular mechanisms for insulin resistance in skeletal muscles and effects of
contraction: Studies in rats fed with carbohydrate solutions or treated with
dexamethasone” (Supervisor: Dr. J. Jensen).
PEER REVIEWED ARTICLES:
M. M. Ibrahim, E. Fjære, E.-J. Lock, L. Frøyland, N. Jessen, S. Lund, H. Vidal, J. Ruzzin. Metabolic impacts of high dietary exposure to persistent organic pollutants in mice. Toxicology Letters In Press, 2012. Impact factor: 3.60
Jérôme Ruzzin and David R. Jacobs Jr. The secret story of fish: decreasing nutritional value due to pollution? British Journal of Nutrition,2012. Impact factor: 3.446. doi:10.1017/S0007114512002048
Jérôme Ruzzin. Public heath concern behind the exposure to persistent organic pollutants and the risk of metabolic diseases. BMC Public Health 12:298 doi:10.1186/1471-2458-12-298, 2012. Impact factor: 2.36. http://www.biomedcentral.com/content/pdf/1471-2458-12-298.pdf
Jérôme Ruzzin, Duk-Hee Lee, David O Carpenter, David R. Jacobs Jr. Reconsidering metabolic diseases: The impacts of persistent organic pollutants. Atherosclerosis, 2012. Impact factor: 4.086; DOI: 10.1016/j.atherosclerosis.2012.02.039
M. M. Ibrahim, E. Fjære, E.-J. Lock, D. Naville, H. Amlund, E.Meugnier, B. Le Magueresse Battistoni, L. Frøyland, L. Madsen, N. Jessen, S. Lund, H. Vidal, J. Ruzzin. Chronic Consumption of Farmed Salmon Containing Persistent Organic Pollutants Causes Insulin Resistance and Obesity in Mice. PLoS ONE 6(9): e25170. doi:10.1371/journal.pone.0025170, 2011. Impact factor: 4.411
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0025170
G. Pilon, J.Ruzzin, L.E. Rioux, C. Lavigne, P.J. White, L. Frøyland, H. Jacques, L. Beaulieu, and A. Marette. Differential effects of various fish proteins in altering body weight, inflammatory status, and insulin sensitivity in high-fat-fed rats. Metabolism doi:10.1016/j.metabol.2010.12.005, 2011. Impact factor: 2.65
J. Ruzzin, R. Petersen, E. Meugnier, L. Madsen, E.J. Lock, H. Lillefosse, T. Ma, S. Pesenti, S. Brask Sonne, T.T. Marstrand, M.K. Malde, Z.Y. Du, C. Chavey, L. Fajas, A.K. Lundebye, C.L. Brand, H. Vidal, K. Kristiansen, L. Frøyland. Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome. Environmental Health Perspectives 118 (4):465-471, 2010. Impact factor: 7.04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854721/pdf/ehp-118-465.pdf
J. Ruzzin, S. Turcotte, V. Leblanc, C. Lavigne, L. Froyland, T. R. Remman and A. Marette. Dietary salmon protein improves insulin sensitivity in high-fat fed obese rats. Annals of Nutrition & Metabolism 51, p347, 2007. Impact factor: 1.24
Jensen J, Jebens E, Brennesvik EO, Ruzzin J, Soos MA, Engebretsen EM, O'Rahilly S, and Whitehead JP. Muscle glycogen inharmoniously regulates glycogen synthase activity, glucose uptake, and proximal insulin signalling. American Journal Physiology Endocrinol Metab 290: E154-E162, 2006. Impact factor: 4.14
Ruzzin J, Wagman AS, and Jensen J. Glucocorticoid-induced insulin resistance in skeletal muscles: defects in insulin signalling and the effects of a selective glycogen synthase kinase-3 inhibitor. Diabetologia 48 (10): 2119-30, 2005. Impact factor: 6.55
Brennesvik EO, Ktori C, Ruzzin J, Jebens E, Shepherd PR, and Jensen J. Adrenaline potentiates insulin stimulated PKB activation via cAMP and Epac: implications for cross talk between insulin and adrenaline. Cellular Signaling 17 (12):1551-9, 2005. Impact factor: 4.10
Jensen J, Ruzzin J, Jebens E, Brennesvik EO, and Knardahl S. Improved insulin-stimulated glucose uptake and glycogen synthase activation in rat skeletal muscles after adrenaline infusion: role of glycogen content and PKB phosphorylation. Acta Physiol Scand 184: 121-130, 2005. Impact factor: 2.81
Ruzzin J and Jensen J. Contraction activates glucose uptake and glycogen synthase normally in muscles from dexamethasone-treated rats. American Journal Physiology Endocrinol Metab 289: E241-E250, 2005. Impact factor: 4.14
Ruzzin J, Lai YC, and Jensen J. Consumption of carbohydrate solutions enhances energy intake without increased body weight and impaired insulin action in rat skeletal muscles. Diabetes Metabolism 31: 178-188, 2005. Impact factor: 2.06
Ruzzin J, Peronnet F, Tremblay J, Massicotte D, and Lavoie C. Breath [13CO2] recovery from an oral glucose load during exercise: comparison between [U-13C] and [1,2-13C]glucose. J Appl Physiol.Aug;95(2):477-82, 2003. Impact factor: 3.66
POPULAR ARTICLES:
http://www.svd.se/mat-och-vin/gifter-gor-laxen-till-halsofara_7362290.svd
http://journalen.hioa.no/journalen/Innenriks/article60004.ece
http://nyheter.uib.no/?modus=vis_nyhet&id=49879
http://www.forskning.no/artikler/2010/januar/239490
http://www.medicaldaily.com/articles/10463/20120626/diabetes-obesity-insulin-resistance-pops.htm
http://www.paneuropeannetworks.com/detail/health/pops-linked-to-growing-problem-of-obesity.html
http://hmunca.blogspot.no/2010/04/environmental-chemicals-obesity-and.html
http://www.environmentalhealthnews.org/ehs/newscience/pops-lead-to-insulin-resistance-in-rats
http://www.sciencedaily.com/releases/2012/06/120626092631.htm
VIDEOS
http://www.youtube.com/watch?v=P4PGWDm_zqU
Main research activities for 2010-2011
· Principal investigator of the project “Searching the origin of the insulin resistance syndrome”. Financed by Research Council of Norway (RCN) (2011-2013).
· Principal investigator and PhD supervisor of the project “Role of marine food to fight metabolic syndrome: evaluating the benefits and risks”. Financed by RCN (2009-2012).
· Principal investigator of the project “Salmon oil and contaminants: impacts on insulin sensitivity and metabolic diseases”. Financed by RCN (2008-2011).