Runar Stokke

Title: Researcher

Phone: +47 55 58 38 61

E-mail: Runar.Stokke@bio.uib.no

Visiting address: Thormøhlensgt. 53 A/B

 

During my PhD. I focused on molecular features responsible for the stability of proteins from thermophilic and hyperthermophilic microorganisms. The study involved enzymology and structural biology.

At present my research is more focused on the total protein expression of single cells to investigate regulation of metabolism as a response to environmental changes.

Furthermore, I`m involved in establishing metaproteomics at the CGB, to investigate the complexity of different communities in the deep biosphere.

Publications in Cristin

Stokke R, Roalkvam I, Lanzen A, Haflidason H, Steen IH (2012). Integrated metagenomic and metaproteomic analyses of an ANME-1-dominated community in marine cold seep sediments. Environemntal microbiology 14(5):1333-1346

Roalkvam I, Jørgensen SL, Yifeng C, Stokke R, Dahle H, Hocking W, Lanzen A, Haflidason H, Steen IH (2011). New insight into stratification of anaerobic methanotrophs in cold seep sediments. FEMS Microbial Ecology 78(2):233-243

Stokke R , Birkeland NK, Steen IH. (2007). Thermal stability and biochemical properties of isocitrate dehydrogenase from the thermoacidophilic archaeon Thermoplasma acidophilum . Extremophiles . Mar; 11(2):397-402

Stokke R, Madern D, Fedøy AE, Karlsen S, Birkeland NK, Steen IH. (2007). Biochemical characterization of isocitrate dehydrogenase from Methylococcus capsulatus reveals a unique NAD(+)-dependent homotetrameric enzyme. Arch. Microbiol . 187(5):361-70

Stokke R , Karlström M, Yang N, Leiros I, Ladenstein R, Birkeland NK, Steen IH. (2007) Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers. Extremophiles . 11(3):481-93

Karlström, M., Stokke, R ., Steen, IH., Birkeland, N-K., and Ladenstein, R. (2005) Isocitrate Dehydrogenase from the Hyperthermophile Aeropyrum pernix : X-ray Structure Analysis of a Ternary Enzyme-Substrate Complex and Thermal Stability. Journal of Molecular Biology 345(3): 559-577.

• The hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus; Regulation of metabolism in response to environmental change
• Metagenomics and metaproteomics of Cold-Seeps and deep arctic hydrothermal vent systems
• Biogoldmine (http://www.uib.no/geobio/en/artikler/2011/04/mining-of-a-norwegian-biogoldmine-through-metagenomics)