Lab leaders
Matrix biology
Within the field of matrix biology we have two major areas of interest.
One concerns the function of cellular interactions with collagen. The project spans from interest in gene regulation of collagen receptor expression to functional studies of collagen receptors in vitro and in vivo.
Another concerns the structure, biosynthesis and function of heparan sulfate proteoglycans, complex molecules found in abundance at cell surfaces and in the extracellular matrix, where they bind to other matrix- and cell -associated molecules.
Our projects include studies of the regulation of the structure and function of heparan sulfate proteoglycans on a cellular and molecular level.
Master's Thesis projects
Our groups has several interesting topics for the degree of MSc. Please visit our Msc page: Gullberg-group, Kusche-Gullberg-group
Matrix biology
The matrix biology group investigates mechanisms of cell adhesion to collagen and the importance of proteoglycan synthesis for cellular function. The projects are within the research areas of cell biology, tumor-stroma interactions and developmental biology. Our work aims at developing new prognostic and therapeutic tools for tumor biology and connective tissue disorders.
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News
Paper evaluated in Faculty of 1000
The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation.
News
- Paper evaluated in Faculty of 1000 (26.11.2010)
- Integrins during evolution (22.05.2009)