Selected publications

List of publications Matrix biology 2005-2010

 

2005 

Bodevin-Authelet, S., Kusche-Gullberg, M., Pummill, P. E., DeAngelis, P. L. and Lindahl, U. (2005). Biosynthesis of hyaluronan: direction of chain elongation. J. Biol. Chem. 280, 8813-8818.

Lindahl, U., Li, J. P., Kusche-Gullberg, M., Salmivirta, M., Alaranta, S., Veromaa, T., Emeis, J., Roberts, I., Taylor, C., Oreste, P. et al. (2005). Generation of "neoheparin" from E. coli K5 capsular polysaccharide. J. Med. Chem. 48, 349-352.

Xu, S., Zhao, L., Larsson, A., Smeds, E., Kusche-Gullberg, M. and Venge, P. (2005). Purification of a 75 kDa protein from the organelle matrix of human neutrophils and identification as N-acetylglucosamine-6-sulphatase. Biochem. J. 387, 841-847.

 

2006

Ai, X., Do, A. T., Kusche-Gullberg, M., Lindahl, U., Lu, K. and Emerson, C. P., Jr. (2006). Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J. Biol. Chem. 281, 4969-4976.

Bystrom, B., Virtanen, I., Rousselle, P., Gullberg, D. and Pedrosa-Domellof, F. (2006). Distribution of laminins in the developing human eye. Invest. Ophthalmol. Vis. Sci. 47, 777-785.

Do, A. T., Smeds, E., Spillmann, D. and Kusche-Gullberg, M. (2006). Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation. J. Biol. Chem. 281, 5348-5356.

Ledin, J., Ringvall, M., Thuveson, M., Eriksson, I., Wilen, M., Kusche-Gullberg, M., Forsberg, E. and Kjellen, L. (2006). Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation. J. Biol. Chem. 281, 35727-35734.

Lu, N., Heuchel, R., Barczyk, M., Zhang, W. M. and Gullberg, D. (2006). Tandem Sp1/Sp3 sites together with an Ets-1 site cooperate to mediate alpha11 integrin chain expression in mesenchymal cells. Matrix Biol.25, 118-129.

Mirtti, T., Nylund, C., Lehtonen, J., Hiekkanen, H., Nissinen, L., Kallajoki, M., Alanen, K., Gullberg, D. and Heino, J. (2006). Regulation of prostate cell collagen receptors by malignant transformation. Int. J. Cancer 118, 889-898.

Zhang, Z. G., Bothe, I., Hirche, F., Zweers, M., Gullberg, D., Pfitzer, G., Krieg, T., Eckes, B. and Aumailley, M. (2006). Interactions of primary fibroblasts and keratinocytes with extracellular matrix proteins: contribution of á2â1 integrin. J. Cell Sci. 119, 1886-1895.

Zhou, Y. W., Thomason, D. B., Gullberg, D. and Jarrett, H. W. (2006). Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling. Biochemistry 45, 2042-2052.

Jakobsson, L., Kreuger, J., Holmborn, K., Lundin, L., Eriksson, I. Kjellén, L. & Claesson-Welsh, L. (2006) ” Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis” Dev. Cell 10, 625-634

Kurup, S., A. Abramsson, J.P. Li, U. Lindahl, L. Kjellén, C. Betsholtz, H. Gerhardt, and D. Spillmann. (2006) “Heparan sulphate requirement in platelet derived growth factor B-mediated pericyte recruitment” Biochem. Soc. Transact. 34, 454-455

van den Born, J., Pisa, B., Bakker, M.A., Celie, J.W., Straatman, C., Thomas, S., Viberti, G.C., Kjellén, L. & Berden, J.H. (2006) “No change in glomerular heparan sulfate structure in early human and experimental diabetic nephropathy” J. Biol. Chem. 281, 29606-29613

 

2007

Ai, X., Kitazawa, T., Do, A. T., Kusche-Gullberg, M., Labosky, P. A. and Emerson, C. P., Jr. (2007). SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation. Development 134, 3327-3338.

Busse, M., Feta, A., Presto, J., Wilen, M., Gronning, M., Kjellen, L. and Kusche-Gullberg, M. (2007). Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation. J. Biol. Chem. 282, 32802-32810.

Gullberg, D. (2007). Neuronal pathways leading to the kidney. Matrix Biol. 26, 407-408.

Langsdorf, A., Do, A. T., Kusche-Gullberg, M., Emerson, C. P., Jr. and Ai, X. (2007). Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration. Dev. Biol. 311, 464-477.

Popova, S. N., Barczyk, M., Tiger, C. F., Beertsen, W., Zigrino, P., Aszodi, A., Miosge, N., Forsberg, E. and Gullberg, D. (2007). Alpha11 beta1 integrin-dependent regulation of periodontal ligament function in the erupting mouse incisor. Mol. Cell Biol. 27, 4306-4316.

Popova, S. N., Lundgren-Akerlund, E., Wiig, H. and Gullberg, D. (2007). Physiology and pathology of collagen receptors. Acta. Physiol. (Oxf) 190, 179-187.

Whiteford, J. R., Behrends, V., Kirby, H., Kusche-Gullberg, M., Muramatsu, T. and Couchman, J. R. (2007). Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways. Exp. Cell Res. 313, 3902-3913.

Zhu, C. Q., Popova, S. N., Brown, E. R., Barsyte-Lovejoy, D., Navab, R., Shih, W., Li, M., Lu, M., Jurisica, I., Penn, L. Z. , Gullberg , D. and Tsao, M.-S. (2007). Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells. Proc. Natl. Acad. Sc.i U S A 104, 11754-11759.

Abramsson, A., Kurup, S., Busse, M., Yamada, S., Lindblom, P., Schallmeiner, E., Stenzel, D., Sauvaget, D., Ledin, J., Ringvall, M., Landegren, U., Kjellén, L., Bondjers, G., Li, J-P, Lindahl, U., Spillmann, D., Betsholtz, C. & Gerhardt, H. (2007) ”Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development” Genes Dev. 21, 316-331

 

2008

Caswell, C. C., Barczyk, M., Keene, D. R., Lukomska, E., Gullberg, D. E. and Lukomski, S. (2008). Identification of the first prokaryotic collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1. J. Biol. Chem. 283, 36168-36175.

Gullberg, D. (2008). Re-programmable tumour cells: cytokines from the immune system assume new roles with the help of stem cells. Scand. J. Immunol. 67, 632-633.

Gullberg, D. (2008). How to keep that stemmy-ness: stem cells in the spotlight. Matrix Biol. 27, 161-162.

Presto, J., Thuveson, M., Carlsson, P., Busse, M., Wilen, M., Eriksson, I., Kusche-Gullberg, M. and Kjellen, L. (2008). Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation. Proc. Natl. Acad. Sci. U S A 105, 4751-4756.

Wiig, H., Gyenge, C., Iversen, P. O., Gullberg, D. and Tenstad, O. (2008). The role of the extracellular matrix in tissue distribution of macromolecules in normal and pathological tissues: potential therapeutic consequences. Microcirculation 15, 283-296.

Carlsson, P., Presto, J., Spillmann, D., Lindahl, U. & Kjellén, L. (2008) ”Heparin/heparan sulfate biosynthesis: Processive formation of N-sulfated domains” J. Biol. Chem. 283, 20008-20014

Kawamura, H., Li, X., Goishi, K., van Meeteren, L.A., Jakobsson^, L., Cébe-Suarez, S., Shimizu, A., Edholm, D., Ballmer-Hofer, K., Kjellén, L., Klagsbrun, M. and Claesson-Welsh, L. (2008) “Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization” Blood 112, 3638-3649

 

2009

Bao, X., Kobayashi, M., Hatakeyama, S., Angata, K., Gullberg, D., Nakayama, J., Fukuda, M. N. and Fukuda, M. (2009). Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. Proc. Natl. Acad. Sci. U S A 106, 12109-12114.

Barczyk, M. M., Olsen, L. H., da Franca, P., Loos, B. G., Mustafa, K., Gullberg, D. and Bolstad, A. I. (2009). A role for alpha11beta1 integrin in the human periodontal ligament. J. Dent. Res. 88, 621-626.

Bystrom, B., Carracedo, S., Behndig, A., Gullberg, D. and Pedrosa-Domellof, F. (2009). Alpha11 integrin in the human cornea: importance in development and disease. Invest. Ophthalmol. Vis. Sci. 50, 5044-5053.

Feta, A., Do, A. T., Rentzsch, F., Technau, U. and Kusche-Gullberg, M. (2009). Molecular analysis of heparan sulfate biosynthetic enzyme machinery and characterization of heparan sulfate structure in Nematostella vectensis. Biochem. J. 419, 585-593.

Gullberg, D. (2009). Shift happens - a paradigm shift for the role of integrins in fibrosis. Matrix Biol. 28, 383.

Johnson, M. S., Lu, N., Denessiouk, K., Heino, J. and Gullberg, D. (2009). Integrins during evolution: Evolutionary trees and model organisms. Biochim. Biophys. Acta 1788, 779-789.

Nystrom, A., Shaik, Z. P., Gullberg, D., Krieg, T., Eckes, B., Zent, R., Pozzi, A. and Iozzo, R. V. (2009). Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood 114, 4897-4906.

Osterholm, C., Barczyk, M. M., Busse, M., Gronning, M., Reed, R. K. and Kusche-Gullberg, M. (2009). Mutation in the heparan sulfate biosynthesis enzyme EXT1 influences growth factor signaling and fibroblast interactions with the extracellular matrix. J. Biol. Chem. 284, 34935-34943.

Svendsen, O. S., Barczyk, M. M., Popova, S. N., Liden, A., Gullberg, D. and Wiig, H. (2009). The α11β1 Integrin Has a Mechanistic Role in Control of Interstitial Fluid Pressure and Edema Formation in Inflammation. Arterioscler. Thromb. Vasc. Biol. 29, 1864-1870.

 

2010

Barczyk, M., Carracedo, S. and Gullberg, D. (2010). Integrins. Cell Tissue Res. 339, 269-280.

Carracedo, S., Lu, N., Popova, S. N., Jonsson, R., Eckes, B. and Gullberg, D. (2010). The fibroblast integrin {alpha}11{beta}1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J. Biol. Chem. 285, 10434-10445.

Lu, N., Carracedo, S., Ranta, J., Heuchel, R., Soininen, R. and Gullberg, D. (2010). The human α11 integrin promoter drives fibroblast-restricted expression in vivo and is regulated by TGF-β1 in a Smad- and Sp1-dependent manner. Matrix. Biol. 29, 166-176.

Smeds, E., Feta, A. and Kusche-Gullberg, M. (2010). Target selection of heparan sulfate hexuronic acid 2-O-sulfotransferase. Glycobiology 20, 1274-1282

Isidor B, Pichon O, Redon R, Day-Salvatore D, Hamel A, Siwicka KA, Bitner-Glindzicz M, Heymann D, Kjellén L, Kraus C, Leroy JG, Mortier GR, Rauch A, Verloes A, David A, Le Caignec C. (2010) Mesomelia-synostoses syndrome results from deletion of SULF1 and SLCO5A1 genes at 8q13. Am. Hum. Genet 87, 95-100