Institutt for biomedisin

Prof. emeritus Torgeir Flatmark (1931 - 2020)


Prof. emeritus fra 2001 til 2017.

10 Utvalgte publikasjoner 2005-2008

1. Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PØ, Sandal T, Lønning PE, Flatmark T, Enger PØ, Bjerkvig R, Sioud M, Stallcup WB (2008)
The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling.
Oncogene. 27, 5182-94.

2. Molnes J, Bjørkhaug L, Søvik O, Njølstad PR, Flatmark T (2008)
Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions.
FEBS J. 275, 2467-81. 

3. Bjørkhaug L, Molnes J, Søvik O, Njølstad PR, Flatmark T (2007)
Allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation.
J Biol Chem. 282, 22757-64.

4. Aukrust I, Hollås H, Strand E, Evensen L, Travé G, Flatmark T, Vedeler A (2007)
The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV.
J Mol Biol. 368, 1367-78.

5. Hollås H, Aukrust I, Grimmer S, Strand E, Flatmark T, Vedeler A (2006)
Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA.
Biochim Biophys Acta. 1763, 1325-34.

6. Terland O, Almås B, Flatmark T, Andersson KK, Sørlie M (2006)
One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime.
Free Radic Biol Med. 41, 1266-71.

7. Aukrust I, Evensen L, Hollås H, Berven F, Atkinson RA, Travé G, Flatmark T, Vedeler A (2006)
Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation.
J Mol Biol.  363, 469-81.

8. Ying M, Flatmark T (2006)
Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+.
FEBS J.  273, 513-22.

9. Barroso JF, Carvalho RN, Flatmark T (2005)
Kinetic analysis and ligand-induced conformational changes in dimeric and tetrameric forms of human thymidine kinase 2.
Biochemistry.  44, 4886-96.

10. Related Articles, LinksLauvrak SU, Hollås H, Døskeland AP, Aukrust I, Flatmark T, Vedeler A (2005)
Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction.
FEBS Lett.  579, 203-6.