BBB seminar: Simon Milling
Inflammatory disease, and the intestine
Institute of Infection, Immunity and Inflammation, University of Glasgow, Scotland, UK
A large proportion of our immune cells are resident in the intestine. It is important to understand the immunology of the intestine to develop vaccines and new therapies for increasingly common inflammatory diseases, including spondyloarthritis and inflammatory bowel disease. In my lab we focus on the T cells that often control the immune response, and the dendritic cells that initially activate these T cells. I will present data generated from experimental animals and from human samples, and discuss how over-active immune responses against our normal intestinal bacteria can not only affect our ability to respond to pathogens, but can also cause inflammatory disease, in the intestine and beyond.
Chairperson: Helge Wiig <email@example.com>, Department of Biomedicine