The Department of Biomedicine

CCBIO seminar: Johannes A. Eble

Beating around the bush, yet hitting the point: CAFs and vasculogenic mimicry vessels as anticancer targets

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Johannes A. Eble
Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Germany

The environment of cancer cells in a tumor mass sets a complex stage, in which the cancer cells progress. Targeting this tumor microenvironment (TME), such as cancer-associated fibroblasts or vasculogenic mimicry vessels, helps in curbing cancer cell growth and invasion. Snake venom components directed against integrins and neuropilin-1 may lead to new ways on how the TME components are drugable targets that make cancer cells vulnerable.

Chairperson: Donald Gullberg, CCBIO