CCBIO seminar: Biaoyang Lin
Critical roles of Chitinase 3-like 1 (CHI3L1) in inflammation, fibrosis and cancer and the transformation from bench to bedside
Zhejiang-California International Nanosystems Institute (ZCNI), Proprium Research Center, Zhejiang University, Hangzhou, China, and Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
Chitinase 3-like protein 1 (CHI3L1) is a key regulatory protein playing important roles in inflammation, which is related to fibrosis and cancer. In this talk, basic biological function of CHI3L1 will be discussed and then the focus will be on the roles of CHI3L1 in liver diseases including nonalcoholic fatty liver disease (NALFD) and hepatitis, and its implications on cancer. Finally, the diagnostic values of CHI3L1 on liver fibrosis and its transformation from bench to bedside will be discussed.
Professor Biaoyang Lin is the Founding Director of the Systems Biology Division of the Zhejiang-California International NanoSystems Institute, Zhejiang University, and affiliated to the Department of Urology, University of Washington, Seattle. His major long-term research interests lie in applying systems biology to understand the biology of inflammation, fibrosis and cancer of liver and prostate, to identify accompanying diagnostic or prediction biomarkers, and to develop novel therapeutic approaches. Dr. Lin published over 100 papers including publications in Science and Nature and also has extensive industry experience. He co-founded two companies and has over 15 patents.
Chairperson: Karl-Henning Kalland, CCBIO