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The Department of Biomedicine
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CCBIO seminar: Sebastian Marwitz

A pathway and spatial biology approach to non-small cell lung carcinoma (NSCLC)

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Sebastian Marwitz
Research Center Borstel, Leibniz Lung Center, Borstel, Germany

Lung cancer is the leading cause of cancer-related death worldwide and many patients have despite recent developments an unfavorable prognosis, which results in an ongoing need for new or combined therapeutic approaches targeting molecular pathways or cellular functions. The transforming growth factor beta (TGFB) pathway is pleiotropically involved in a multitude of processes at the cellular level and is considered as either pro- or anti-tumorigenic, depending on the microenvironment and stage of carcinogenesis. The talk will be focused on TGFB signaling as well as spatial biology approaches in lung cancer.

Chairperson: Donald Gullberg, CCBIO