The Department of Biomedicine

BBB Seminar: Kamal Babikeir Eln Mustafa

Stem cells and biomedical engineering

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Kamal Babikeir Eln Mustafa
Department of Clinical Dentistry, University of Bergen

Bone defects due to ablative surgery, injuries and to pathological and physiological bone resorption still represent a major challenge for oral/maxillofacial surgeons and periodontologists. Due to the complicated anatomy and physiology of bone tissue, as well as the limitations in the current medical technology, clinical treatments to repair bone defects are problematic and often yield poor healing. Tissue engineering has emerged as an interdisciplinary field for regenerative therapy of bone defects with tremendous potential to improve and replace the current classic strategies. Significant growth opportunities exist for synthetic bone grafts in association with mesenchymal stem cells from autologous or allogenic sources as alternatives to biological bone grafts.

This lecture covers research areas of central importance for bone tissue repair, including biomaterial scaffolds for tissue engineering, mesenchymal stem cells, osteogenesis and its molecular markers. A variety of cells, in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, will be discussed.

Host: Ellen Berggreen, Department of Biomedicine