The PROMISE Research Consortium

Promoting infant health and nutrition in Sub-Saharan Africa

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Here you will find information about PROMISE. Our projects, team and collaborators.

History:

The PROMISE Research Consortium was founded in 2003 by 4 African partners: Centre Muraz, Burkina Faso; Makerere University, Uganda; University Teaching Hospital and University of Zambia, Zambia; University of the Western Cape, South Africa and 3 European partners: University of Bergen, Norway; University of Montpellier/INSERM U1058, France and Uppsala University, Sweden. We have run a number of studies and trials (see list of projects). Uppsala University, Sweden left the collaboration after the PROMISE EBF trial was completed in 2011. All collaboration involving three or more of the partners are counted as PROMISE studies/trials and included in this web site. In addition, there are several projects/studies/trials involving only two of the partners.

Our projects:

The EBF-group:

Steering Committee: Thorkild Tylleskär, Philippe Van de Perre, Eva-Charlotte Ekström, Nicolas Meda, James K. Tumwine, Chipepo Kankasa, Debra Jackson

Participating countries and investigators: (Country PI first, others in alphabetical order of surname)

Norway: Thorkild Tylleskär, Ingunn MS Engebretsen, Lars Thore Fadnes, Eli Fjeld, Knut Fylkesnes, Jørn Klungsøyr, Anne Nordrehaug-Åstrøm, Øystein Evjen Olsen, Bjarne Robberstad, Halvor Sommerfelt

France: Philippe Van de Perre

Sweden: Eva-Charlotte Ekström

Burkina Faso: Nicolas Meda, Hama Diallo, Thomas Ouedrago, Jeremi Rouamba, Bernadette Traoré Germain Traoré, Emmanuel Zabsonré

Uganda: James K. Tumwine, Caleb Bwengye, Charles Karamagi, Victoria Nankabirwa, Jolly Nankunda, Grace Ndeezi, Margaret Wandera

Zambia: Chipepo Kankasa, Mary Katepa-Bwalya, Chafye Siuluta, Seter Siziya

South Africa: Debra Jackson, Mickey Chopra, Mark Colvin, Tanya Doherty, Ameena E Googa, Lyness Matizirofa, Lungiswa Nkonki, David Sanders, Wanga Zembe

PROMISE

UiB coordinator: Thorkild Tylleskär

Website: PROMISE: Promoting infant health and nutrition in Sub-Saharan Africa (ext link)

Photo:

The PROMISE project

Projects and news

PROMISE consortium published in Nature

The PROMISE consortium has published the results of their long-term study showing similar long-term clinical outcomes from early use of two different HIV prophylactic drugs in Nature.

PROMISE EBF: Safety and efficacy of exclusive breastfeeding promotion in the era of HIV

Exclusive breastfeeding (EBF) for the first six months is an effective child survival strategy.

PROMISE SB: Saving Brains in Uganda and Burkina Faso

Exclusive breastfeeding (EBF) has been associated with better cognition in some developed countries. In this project scientists from Uganda and Burkina Faso will assess whether EBF promotion enhances human capital formation including cognitive function, mental and general health.

PROMISE PEP: Prevention of mother to child transmission of HIV

A randomised controlled trial comparing the efficacy of infant peri-exposure prophylaxis with Lopinavir/Ritonavir (LPV/r) versus Lamivudine to prevent HIV-1 transmission by breastfeeding

PROMISE M & S

Infant Peri-Exposure Prophylaxis to Prevent HIV-1 Transmission by Breastfeeding: Mechanisms & Safety

Promise-EPI Study

In spite of antiretroviral therapy, ART to HIV-positive mothers, breastfeeding transmission of HIV remains too high in many African countries. Our primary objective is to evaluate the efficacy of an innovative intervention to protect HIV-1-exposed uninfected infants.

The PROMISE-ZERO study

Most cases of paediatric HIV now occur during the breastfeeding period. In the last twenty years, considerable progress has been achieved to improve policies and scale up the roll out of...

28.11.2023