Centre for International Health
Research project

DATURA – Better treatment for patients with tuberculosis and HIV co-infections

The project aims to assess whether an intensified initial TB treatment can increase survivability in hospitalised, HIV-infected adults and adolescents compared to the standard TB treatment regime.


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The Datura project is a multidisciplinary international research project involving four countries in four different sub-Saharan regions, two countries in Southeast Asia and two European academic institutions. It is studying the effect of using a modified TB treatment protocol in severely immunosuppressed TB patients. The name, Datura, is an acronym for: Determination of Adequate TUberculosis Regimen in Adults and Adolescents hospitalised with HIV-associated severe immune suppression.

The project is a collaboration between researchers in Norway, France, Zambia, Guinea, Cameroon, Uganda, Cambodia and Mozambique. It is co-ordinated by a research team at the Centre Hospitalier Universitaire de Montpellier in France. The project is funded by the European & Developing Countries Clinical Trials Partnership (EDCTP). Datura also addresses SDG Goal 3, target 3.3, aiming to end the epidemics of AIDS and TB, among others, by 2030.

Read more about Datura