Level of Study
Masters, PhD, or a combination
Place of Instruction
Objectives and Content
The student shall achieve knowledge on animal research and demonstrate that they can apply this knowledge in a new context, for example when planning own experiments or when evaluating or give input to plans of animals experiments. They must achieve knowledge necessary and useful when they are performing procedures in practice or evaluate suggested practical solutions.
They must be capable of evaluating common practice on light of new knowledge about alternative ways to do animal experiments. This includes methods that reduce negative impact on the animals (refinement), means that improve the conditions for the animals (refinement), planning and designing experiments to optimize knowledge output with the use of as few animals as possible (reduction) and use alternatives to animals whenever they are available (replacement).
The course shall cover the core module of Mattilsynets and the EU-directives (2010/63) demands to theoretical tra8ining for persons performing procedures (function A) and designing experiments (function B).
The aim is to give the students an introduction to central topics in LAS and make them available to apply this when panning and performing own experiments.
- Laboratory animal science (LAS) is a multidisciplinary branch of science contributing to human use of animals and collection of informative, reproducible and unbiased information
- LAS covers regulations ethics, external factors, factors with the animal themselves, literature search and design of experiments and how these factors influence experiment.
In LAS302 the following topics are covered
- Basic biological needs and behaviour.
Reproduction and gene-modified animal
- Health qualities and health monitoring
- Diet and nutrition
- Environmental conditions
- Anaesthesia and pain relieve
- Aseptic and surgical techniques
Persons performing procedures (function A) at UiB go through the same training program as function B, and in addition they must demonstrate that they master procedures properly to work independently without negative impact on the animals or on the experiments. Practical training must be tailor-made to the specific experiment and is therefore not a part of LAS302.
After the education the students shall have achieved the following learning outcome.
For rodents and pigs, the student must describe
- Basic physiology, reproduction and behaviour
- Dietary needs, practical feeding and watering. Storage and preparation of food and water.
- Know characteristics of common strains and how this can influence animal welfare and science
- When relevant, describe how modulation of genome can influence phenotype
- Appropriate routine for housing and husbandry of the species.
- How photoperiod can influence animal experiments
- Biological consequences of acclimatising, habituation and training
- How the animal facility is organized to take care of animal health as well as scientific procedures
- A breeding program
- How Gene-modified animals can be useful in research and the importance of good monitoring av such animals.
Generic knowledge: This course focuses on rodents and pigs. Similar factors are important also for other species.
Required Previous Knowledge
Recommended Previous Knowledge
Student should have some knowledge of anatomy and physiology. LAS301 is an advantage but not a formal demand
Access to the Course
The course is available for Master students and PhD students at The Faculty of Medicine, The Faculty of Mathematics and Natural Sciences and The Faculty of Psychology
Teaching Methods and Extent of Organized Teaching
- Litterature/pensum (approx. 220 pages)
- Tradisjonal lectures
Compulsory Assignments and Attendance
All lectures are mandatory
Forms of Assessment
60 minutes digital (multiple choice) exam
Will be continously updated
There will be evaluation of the teaching after the course
Aurora Margrethe Brønstad: Aurora.Bronstad@uib.no