Lipid Biochemistry: From Chemistry to Diseases

ECTS Credits

10

Level of Study

Bachelor

Teaching semester

Autumn.

This course has a limited capacity, enrolment is based on application. The application deadline is Wednesday in week 33 for the autumn semester. Please see this page for more information. You will receive confirmation of whether you received a seat in Studentweb no later than Monday the week after the deadline.

It is compulsory to attend the first lecture/orientation meeting, or you risk losing your seat. If you are unable to attend the first lecture, you must contact the Study Section (<email>studie.bio@uib.no</email>). The time of the first lecture/orientation meeting can be found in the schedule on the course website or on Mitt UiB.

Objectives and Content

Objectives:

The course aims to deepen the knowledge acquired in basic lipid biochemistry and to further understand the properties of lipids at the chemical, molecular and biological levels that contribute to cellular function and diseases.

Content:

The course covers the following main areas: properties and function of membrane and intracellular lipids, the biochemical and biological significance of lipid-protein interactions, advanced lipid methodology and lipid-related diseases

Learning Outcomes

On completion of the course the student should have the following learning outcomes defined in terms of knowledge, skills and general competence:

Knowledge

The student

• can explain phospholipid biosynthetic and catabolic pathways
• can explain methods of lipid analysis
• can describe and understand how lipid assemble into membranes and accommodate for trans-membrane proteins
• can explain lipid-protein interactions at membranes and their functions
• can describe lipid modification of proteins chemically and functionally
• can explain lipid-mediated signaling and its role in cellular processes
• can describe different lipid-mediated diseases at the molecular level

Skills

The student

• is able to apply new knowledge and principles to understand molecular mechanisms of normal cellular processes and lipid-related diseases
• to participate and to report in a small team provided with question-based assignments

General competence

The student can demonstrate advanced knowledge in lipid biochemistry and is able to apply it in a wider biochemical and biological context

Required Previous Knowledge

MOL100 and KJEM130 (or equivalent). The course is best suited for master studies, or at the 5th or 6th semester of the bachelor program.

Recommended Previous Knowledge

None

Credit Reduction due to Course Overlap

None

Teaching and learning methods

Lectures, tutorials

Compulsory Assignments and Attendance

1 obligatory written assignment based on a recent research article. Mandatory activity is valid for five subsequent semesters. All obligatory activity must be approved before one can take the exam.

Forms of Assessment

Written exam 4 hours.

Examination support materials: None

Examination Support Material

None

Grading Scale

The grading scale used is A to F. Grade A is the highest passing grade in the grading scale, grade F is a fail.