Flow chemistry and technology

ECTS Credits

10

Level of Study

Master

Teaching semester

Autumn

Place of Instruction

Bergen

Objectives and Content

Objectives:

The course aims to give the candidate theoretical knowledge and practical skills at a high level within flow chemistry and technology. The candidate should be able to utilize the established knowledge and take part in an innovative and further development of the field of flow chemistry and technology. The course also provides the students training in searching and evaluating relevant scientific literature.

Contents:

Basic theoretical knowledge of how to design the manufacture micro--rectors and their characteristics, in-situ reaction monitering, and the limitations and advantages of flow reactor systems. Advanced knowledge and general skills in the use of flow reactors, micro mixers, pumps and other devices included in the flow reactor systems. Furthermore, experimental experience acquired through assignments and demonstrations where flow reactor systems are used for the synthesis of a variety organic target molecules, such as intermediates for pharmaceuticals, active ingredients (drugs) and the analysis of pharmaceuticals, metabolites and biomarkers contained in the biological material.

Learning Outcomes

On completion of the course the student should have the following learning outcomes defined in terms of knowledge, skills and general competance:

Knowledge

The student

• possesses a broad knowledge about flow-chemistry and the technology
• has knowledge about instrumentation used in the field, understand the limitations and advantages of the flow-chemistry and technology
• possess knowledge about how flow chemistry processes can be developed and used for the production of pharmaceutical chemicals.

Skills

The student

• can perform professional development and use technologies and methods in flowchemistry for the production of intermediates and active substances for application as drug substances
• design experiments and conduct experiments in the laboratory
• describe and use flow reactor technology of importance for drug synthesis and other fine chemicals applications
• communicate and cooperation with other professionals

General competance

Students

• can analyze and identify issues in flow-chemistry associated with the synthesis of drugs substances, intermediates and other fine chemicals
• can used their skills and knowledge in an innovative in the field of flow-chemistry
• have knowledge about scientific methods and instrumentation required for working with flow-technology
• can communicate professional issues, with both professionals and in popularized form
• can contribute to innovative technology development for flow-chemistry applications.

Required Previous Knowledge

KJEM130, KJEM131, KJEM250, KJEM230/KJEM235

Recommended Previous Knowledge

KJEM110, KJEM120, KJEM140, PHYS225, KJEM231

Access to the Course

To gain acess to this course, one must be enrolled in the Integrated Masters programme for Medical Technology at the Faculty for Mathematics and Natural Sciences. Students at Masterprogramme in Chemistry (chemical synthesis) may also be able to take the course if available capacity on the course.

Teaching and learning methods

The teaching will be provided as lectures, seminars and laboratory work.

Compulsory Assignments and Attendance

Laboratory excersizes and laboratory demonstration. The compulsory activities are valid for two (2) consecutive semesters after the approval.

Forms of Assessment

Written examiniation (60%) and assessment of laboratory reports (40%)

Examination Support Material

None

Grading Scale

The grading scale used is A to F. Grade A is the highest passing grade in the grading scale, grade F is a fail.

Assessment Semester

Spring semester and autumn semester. In semester without teaching is examination early in the semester.

Course Evaluation

The course will be evaluated by the students in accordance with the quality control system at UiB and the department.

Programme Committee

The programme committee is responsible for the content, structure and quality of the programme and courses.

Course Coordinator

Contact information for the course coordinator is available at MittUiB, alternatively contact the student advisor.

Course Administrator

The Faculty of Mathematics and Natural Sciences and Chemistry Department are administratively responsible for the course.