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Causes and Mechanisms of Disease Group

The group investigates how genetic variation contribute to disease using multiple approaches.

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Working Dat at Genomics Group
Photo:
Stefan Johansson
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Causes and mechanisms of disease picture. Effect sizes of SNPs at timepoints.
Effect sizes for all time points. Regression betas are plotted in BMI-sd units at each time point for lead SNPs in LEPR (rs2767486), ADCY3 (rs13035244), LCORL (rs6842303), LEP (rs10487505), and FTO (rs9922708).
Photo:
Øyvind Helgeland
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Group leader: Stefan Johansson

Our team investigates how genetic variation contribute to disease using approaches such as GWAS in large cohorts, genome and transcriptome sequencing in rare monogenic disorders, and in depth functional analyses in cell models and zebra fish.

Key expertise

  • GWAS
  • Triad
  • RNA-seq
  • Proteomics
  • Pathway analysis
  • Transcriptomics
  • Metabolomics
  • Methylation

Resources

  • Helseundersøkelsene i Hordaland (HUSK)
  • Norwegian Mother and Child Sudy (MoBa) cohort
  • MODY Registry
  • Child Diabees Registry
  • ROAS biobank

Alle publications

Latest publications