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Department of Clinical Medicine

Pancreas Research Group

The pancreas secretes digestive enzymes and is at the same time a hormone-producing organ that regulates glucose metabolism. Our research group focuses on the molecular mechanisms involved in development of pancreatic disease.

A microscopic section of pancreatic tissue (200X magnification). In the...
A microscopic section of pancreatic tissue (200X magnification). In the middle of the picture, a hormone-producing islet of Langerhans is present. It is surrounded by enzyme-secreting acinar cells, whereas two exocrine ducts are seen in the upper left and right corners.

The pancreas serves both exocrine and endocrine functions in the body. Most of the organ’s mass consists of exocrine tissue that produces digestive enzymes and delivers them to the alimentary tract. The endocrine cells are found as islets of Langerhans, which are dispersed throughout the pancreas and serve a fundamental role in regulating glucose metabolism.

Our research group is interested in molecular pathology, i.e. molecular mechanisms involved in disease development. We are studying several disorders that affect the pancreas:

  • Inherited (monogenic) diabetes
  • Congenital hyperinsulinism of infancy
  • Pancreatic cancer
  • Exocrine pancreatic dysfunction/chronic pancreatitis

For a description about our projects and a list of group members and publications, please visit our web pages.  The group is headed by professor Anders Molven.

Our research activities are supported by the Helse Vest Regional Health Authority, KG Jebsen Foundation and NOVO Nordisk Foundation.