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Anne-Kristin Støbakk Stavrum's picture

Anne-Kristin Støbakk Stavrum

Researcher
  • E-mailAnne-kristin.Stavrum@uib.no
  • Phone+47 55 97 70 33+47 926 96 663
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen

I am working as a researcher in Professor Stephanie Le Hellards lab, which focuses on the epigenetics of mental disorders. We are part of the Dr. Einar Martens Research Group for Biological Psychiatry and the Norwegian Center for Mental Disorders Research (NORMENT).

We are working on several project where we study the interaction between the environment and genetic background, and how this affect variations in gene regulation and expression.

Current projects include epigenetic effects of

  • Cannabis usage
  • Anti-psychotic drugs
  • Alcohol
  • Childhood trauma

An underestimated factor in most studies is sex. Several disorders display sex imbalances, which can be observed as differences in disease prevalence, onset or outcome. Sex differences are driven by the sex chromosomes and sex specific environment (incl. hormones). Understanding how sex differences impact the genetic architecture of complex disorders is something we are particularly interested in.

 

  • Show author(s) 2020. Epigenetic Effects of THC and CBD in Neuronal Stem Cells.
  • Show author(s) 2020. Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder. Frontiers in Psychiatry. 1-10.
  • Show author(s) 2018. Gene expression response in peripheral blood cells of petroleum workers exposed to sub-ppm benzene levels. International Journal of Environmental Research and Public Health (IJERPH). 1-18.
  • Show author(s) 2017. SBMLmod: a Python-based web application and web service for efficient data integration and model simulation. BMC Bioinformatics. 1-8.
  • Show author(s) 2016. Tissue specific models of Tryptohan-metabolism — insights into metabolic crosstalk.
  • Show author(s) 2016. Tissue specific models of Trp- and NAD-metabolism — insights into metabolic crosstalk.
  • Show author(s) 2015. Dynamics of NAD-metabolism - everything but constant.
  • Show author(s) 2014. Predicting pathological metabolic changes using a kinetic model of tryptophan metabolism.
  • Show author(s) 2014. NAD-metabolism and the circadian clock -- Unraveling contradictions.
  • Show author(s) 2014. Interactively illustrating polymerization using three-level model fusion. BMC Bioinformatics.
  • Show author(s) 2014. Illustrative visualization of molecular reactions using omniscient intelligence and passive agents. Computer Graphics Forum. 141-150.
  • Show author(s) 2014. A kinetic model of tryptofan metabolism - Developments towards accurate and scalable kinetic models.
  • Show author(s) 2013. NAD-metabolism and the circadian clock.
  • Show author(s) 2013. Model of tryptophan metabolism, readily scalable using tissue-specific gene expression data. Journal of Biological Chemistry. 34555-34566.
  • Show author(s) 2013. Effect of substrate competition in kinetic models of metabolic networks. FEBS Letters. 2818-2824.
  • Show author(s) 2012. Mycobacterium tuberculosis Mcel protein complex initiates rapid induction of transcription of genes involved in substrate trafficking. Genes and Immunity. 496-502.
  • Show author(s) 2011. Modulation of transcriptional and inflammatory responses in murine macrophages by the mycobacterium tuberculosis mammalian cell entry (Mce) 1 complex. PLOS ONE. 11 pages.
  • Show author(s) 2011. Hepatic in vitro toxicity assessment of PBDE congeners BDE47, BDE153 and BDE154 in Atlantic salmon (Salmo salar L.). Aquatic Toxicology. 246-263.
  • Show author(s) 2010. Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. PLOS ONE. 12 pages.
  • Show author(s) 2010. From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery. Endocrine journal. S429-S429.
  • Show author(s) 2010. From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery.
  • Show author(s) 2009. Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L). Molecular Vision. 1332-1350.
  • Show author(s) 2009. Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L).
  • Show author(s) 2008. Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.). BMC Pharmacology. 14 pages.
  • Show author(s) 2007. Zebrafish as a genetic model for the nutritional impact on growth in fish.
  • Show author(s) 2007. The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice. Arthritis Research & Therapy. 1-15.
  • Show author(s) 2007. Synaptic activity-induced global gene expression patterns in the dentate gyrus of adult behaving rats: Induction of immunity-linked genes. Neuroscience. 925-936.
  • Show author(s) 2007. Gene-expression profiling in gill and liver of zebrafish exposed to produced water. International Journal of Environmental Analytical Chemistry. 195-210.
  • Show author(s) 2006. Dynamics of global macrophage expression responses to in vitro infection with wild-type and a hypervirulent mce1-mutant of M. tuberculosis.

More information in national current research information system (CRIStin)

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