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Aurora Margrethe Brønstad's picture

Aurora Margrethe Brønstad

Researcher
K1: Dyreavdelingen
  • E-mailAurora.Bronstad@uib.no
  • Phone+47 55 97 37 82+47 909 58 067
  • Visitor Address
    Haukeland universitetssykehus
  • Postal Address
    Postboks 7804
    5020 Bergen

Laboratory Animal Science

Reseracher

Academic article
  • Show author(s) (2022). Intestinal permeability and gene expression after polyethylene and polyamide microplastic ingestion in Wistar rats. Toxicology Letters. 35-41.
  • Show author(s) (2022). Good Anesthesia Practice for Fish and Other Aquatics. Biology (Basel).
  • Show author(s) (2019). Examining compliance with ethical standards for animal research: is there a need for refinement? A qualitative study from northern Europe. Laboratory Animals. Journal of the Laboratory Animal Science Association. 1-9.
  • Show author(s) (2016). Recommendations for addressing harm-benefit analysis and implementation in ethical evaluation - Report from the AALAS?FELASA working group on harm-benefit analysis - Part 2. Laboratory Animals. Journal of the Laboratory Animal Science Association. 21-42.
  • Show author(s) (2016). Current concepts of harm-benefit analysis of animal experiments - Report from the AALAS-FELASA working group on harm-benefit analysis - Part 1. Laboratory Animals. Journal of the Laboratory Animal Science Association. 1-20.
  • Show author(s) (2011). The role of organizational culture in compliance with the principles of the 3Rs. Lab animal. 22-26.
  • Show author(s) (2007). Airway inflammation and bronchial remodelling in toluene diisocyanate-exposed BALB/c mouse model. Scandinavian Journal of Immunology. 118-125.
  • Show author(s) (2004). Problems in physiological experimental animal models investigated with factorial design. Journal of Experimental Animal Science. 1-12.
  • Show author(s) (2004). Effects of the taxanes paclitaxel and docetaxel on edema formation and interstitial fluid pressure. American Journal of Physiology. Heart and Circulatory Physiology.
  • Show author(s) (2004). Effect of the cytoskeletal fixation agent phalloidin on transcapillary albumin transport and interstitial fluid pressure following subdermal prostaglandin E-1 administration in the rat. Acta Physiologica Scandinavica. 125-132.
  • Show author(s) (2004). Continuous measurements of plasma protein extravasation with microdialysis after various inflammatory challenges in rat and mouse skin. American Journal of Physiology. Heart and Circulatory Physiology. H108-H112.
  • Show author(s) (1994). Et tilfelle av systemisk mastocytose og myeloid proliferasjon hos hund. Norsk Veterinærtidsskrift. 289-296.
Lecture
  • Show author(s) (2021). FISHEND/FISHENDS-DIG.
  • Show author(s) (2019). Introduction and Humane endpoints at Severity and humane endpoints in fish research.
  • Show author(s) (2019). Humane endpoint – Concept and misconceptions.
  • Show author(s) (2019). How to perform literature searches and systematic reviews.
  • Show author(s) (2019). Harm-Benefit Assessment and Public Summary .
  • Show author(s) (2019). Harm-Benefit Assessment & Public Project Summary.
  • Show author(s) (2018). Typical Findings and Quality Expectations for Ethical Review and Oversight. The AAALAC Experience.
  • Show author(s) (2018). Lansering: Etiske retningslinjer for bruk av dyr i forskning.
  • Show author(s) (2018). Harm-Benefit analysis The AAALAS-FELASA Working group approach.
  • Show author(s) (2018). Harm-Benefit analysis - Current concepts and practical approaches.
  • Show author(s) (2017). How to inegrate severity calsification into Harm-Benefit Analysis.
  • Show author(s) (2017). Harm-Benefit Analysis.
  • Show author(s) (2016). Harm Benefit analyse forsøksdyretikk.
  • Show author(s) (2014). Harm-Benefit Analysis of Research Proposals: A tool for practical Implementation.
  • Show author(s) (2014). Harm-Benefit Analysis of Animal experiments – an update from the AALAS-FELASA Working group.
  • Show author(s) (2014). Harm-Benefit Analysis of Animal experiments – an update from the AALAS-FELASA Working group.
Academic lecture
  • Show author(s) (2022). One Health / Én helse.
  • Show author(s) (2019). Harm-Benefit analysis The AAALAS-FELASA Working group approach .
  • Show author(s) (2016). Harm Benefit Analysis the AALAS-FELASA Working Group proposal an update.
  • Show author(s) (2016). Harm Benefit Analysis the AALAS FELASA Working Group proposal.
  • Show author(s) (2013). Harm-Benefit Analysis: An Ethical Framework for conducting Humane Animal Research. Update from the AALAS-FELASA Joint Working group on Harm-Benefit Analysis.
  • Show author(s) (2011). Project authorization "ethical approval" in Norway and establishing ethical committees.
  • Show author(s) (2011). How does repeated anaesthesia effect on animals: physiological and welfare aspects.
  • Show author(s) (2011). Bruk av score-sheet og aktivitetskart og hvordan utfyller disse hverandre?
  • Show author(s) (2010). 3R compliance, culture and consequeses, p24-28 in Proceedings of New Paradigms in Laboratory Animal Science.
  • Show author(s) (2009). The challenge of arranging accredited courses for fish researchers and technicians.
  • Show author(s) (2009). Refinement, Reduction and animals imaging.
  • Show author(s) (2009). Norecopa Norway´s concensus platform for replacement, reduction and refinement of animals experimenst.
  • Show author(s) (2009). Laboratory Animal Science for inspectors of the Food safety Authority in Norway.
Academic anthology/Conference proceedings
  • Show author(s) (2021). Experimental Design and Reproducibility in Preclinical Animal Studies. Springer Nature.
Letter to the editor
  • Show author(s) (2019). Response to the article “Mapping the Teaching of Laboratory Animal Science and Medicine in the European Union and European Free Trade Area”. Journal of Veterinary Medical Education.
Doctoral dissertation
  • Show author(s) (2004). Interstitial fluid pressure and transcapillary fluid and solute flux in acute inflammation: Modulation by cytoskeletal fixation.
Interview
  • Show author(s) (2022). Dyr viktigere for eldre under pandemien: – Blir medisin for dem.
  • Show author(s) (2021). Mener terapi med dyr kan føre til mindre bruk av medisiner.
  • Show author(s) (2021). Hesteterapi i Medisinutdanningen.
  • Show author(s) (2021). Hesteassistert terapi - Veronica Sellevold vlog27.
  • Show author(s) (2021). Gir unik opplæring i dyreterapi til UiB-studenter.
  • Show author(s) (2021). Dette foregår bak dørene til UiBs dyreavdeling.
  • Show author(s) (2019). Hvorfor er mus så mye brukt som forsøksdyr?
  • Show author(s) (2016). Håpar dyreforsøk snart blir overflødig.
  • Show author(s) (2016). Forsøksdyrenes forsvarer.
Academic chapter/article/Conference paper
  • Show author(s) (2011). Imaging techniques. 26 pages.
  • Show author(s) (2011). Ethical evaluation of procedures for experiments involving animals. Recommendations for ethics committees. 30 pages.
Poster
  • Show author(s) (2020). Effects of orally ingested microplastics in rats as a model organism: preliminary results .
  • Show author(s) (2018). The change of roles in the veterinary profession.
  • Show author(s) (2018). The art of comparing apples and oranges – Proposal from the AALAS - FELASA working group on harm-benefit analysis of animal studies.
  • Show author(s) (2011). The use of activity maps in project authorization.
  • Show author(s) (2011). Control of workstations for gas anesthesia and gas anesthesia apparatuses for rodents.
Website (informational material)
  • Show author(s) (2021). "Humane endpoints" on https://wiki.norecopa.no/index.php/Humane_endpoints.
Chapter
  • Show author(s) (2021). Harm to research animals, severity categories, and humane endpoints. 207-240. In:
    • Show author(s) (2021). Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU. Academic Press.

More information in national current research information system (CRIStin)

Publikasjoner i tidsskift og bøker

1.Brattebo J, Brattebo G, Wisborg T, Lonn R, Pillgram-Larsen J, and Bronstad AM. How do surgical teams train emergency surgical interventions? Tidsskr Nor Legeforen 121: 1513-1515, 2001.

2.Bronstad A, Berg A, and Reed RK. Effects of the taxanes paclitaxel and docetaxel on edema formation and interstitial fluid pressure. Am J Physiol Heart Circ Physiol 287: H963-968, 2004.

3.Bronstad A, Reed RK, and Berg A. Effect of the cytoskeletal fixation agent phalloidin on transcapillary albumin transport and interstitial fluid pressure following subdermal prostaglandin E1 administration in the rat. Acta Physiol Scand 180: 125-132, 2004.

4.Bronstad A, Reith A, Berg A, and Reed RK. Effect of the cytoskeletal fixation agent phalloidin on transcapillary albumin transport and interstitial fluid pressure in anaphylaxis in the wistar rat. Microcirculation 9: 197-205, 2002.

5.Brønstad A, Jenssen M, Ulstein T, Espenes A, and Sjaastad Ø. Et tilfelle av systemisk mastocytose og myeloid proliferasjon hos hund. Norsk Veterinær Tidsskrift 4: 289-295, 1994.

6.Brønstad AM. Interstitial fluid pressure and transcapillary fluid and solute flux in acute inflammation: modulation by cytoskeletal fixation. [Bergen]: Department of Biomedicine, Div. for Physiology, University of Bergen, 2004.

7.Gjerde EA, Eide DM, Bronstad A, and Reed RK. Problems in physiological experimental models investigated with factorial design. J Exp Animal Sc 43: 1-12, 2004.

8.Iversen VV, Bronstad A, Gjerde EA, and Reed RK. Continuous measurements of plasma protein extravasation with microdialysis after various inflammatory challenges in rat and mouse skin. Am J Physiol Heart Circ Physiol 286: H108-112, 2004.

9.Sun LZ, Elsayed S, Bronstad AM, Van Do T, Irgens A, Aardal NP, and Aasen TB. Airway inflammation and bronchial remodelling in toluene diisocyanate-exposed BALB/c mouse model. Scand J Immunol 65: 118-125, 2007.

10 Brønstad A, Dontas I. Imaging techniques. In Howard B, Perretta G, Nevalainen T (eds): COST Manual for the care and use of laboratory animals: Refinement, reduction and research. CRC press Oct 2010, ISBN:  9781439824924 (p287-312)

11 Rony Kalman R, I Anna Olsson, Claudio Bernardi, Frank van den Broek, Aurora Bronstad, Istvan Gyertyan, Aavo Lang, Katerina  A. Marinou, Walter Zeller. Ethical evaluation of procedures for experiments involving animals. Recommendations for ethics committees. In Howard B, Perretta G, Nevalainen T (eds): COST Manual for the care and use of laboratory animals: Refinement, reduction and research. CRC press Oct 2010, ISBN:  9781439824924 (p101-130)

12 ESF.EMRC Position on the Proposal for a Directive on the Protection of Animal used for Scientific Purposes, European Science Foundation – expert group

13 The role of orgaizational culture in compliance with the 3Rs, Aurora Brønstad, Faculty of Medicine and Dentistry, University of Bergen, Norway, Anne-Grethe Trønsdal BergHøgskolen i Nord-Trøndelag, Norway, Lab Animal - 40, 1 (2011) p 22-26

14 3R CULTURE, COMPLINACE and CONSEQUENCES Aurora Brønstad, Faculty of Medicine and Dentistry, University of Bergen, Norway, Anne-Grethe Trønsdal Berg Høgskolen i Nord-Trøndelag, Norway FELASA proceedings page 24-28

15 Current concepts of harm–benefit analysis of animal experiments – Report from the AALAS–FELASA working group on harm–benefit analysis – Part 1 Aurora Brønstad, Christian E Newcomer, Thierry Decelle, Jeffrey I Everitt, Javier Guillen and Kathy Laber. Laboratory Animals June 2016 vol. 50 no. 1 suppl 1-20

16 Recommendations for addressing harm–benefit analysis and implementation in ethical evaluation Report from the AALAS–FELASA working group on harm–benefit analysis – Part 2. Kathy Laber, Christian E Newcomer, Thierry Decelle, Jeffrey I Everitt, Javier Guillen and Aurora Brønstad Laboratory Animals Lab Anim June 2016 vol. 50 no. 1 suppl 21-42

17 Current Concepts of Harm-Benefit Assessment of Animal Research - A Mini Review – Aurora Brønstad, Journal of Infectiology 2018; 1(1): 16-18

18 Examining compliance with ethical standards for animal research - is there a need for refinement? – A qualitative study. Aurora Brønstad, Department of clinical medicine, University of Bergen, Norway, Peter Sandøe, Department of Veterinary and Animal Sciences and Department of Food and Resource Economics, University of Copenhagen, Denmark – submitted

19 Response to the article “Mapping the Teaching of Laboratory Animal Science and Medicine in the European Union and European Free Trade Area” Aurora Brønstad and Peter Glerup. Letter to editor, Journal of Veterinary Medical Education 2019 46:1

20 Book chapter:  "Harm to research animals, severity categories, and humane endpoints" page 207-240  by Aurora Brønstad "Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU"  327 pg. by Gianni Dal Negro – November 18t,h 2022 by ELSEVIER 50 Hampshire St., 5th Floor, Cambridge, MA 02139, USA 

21 Experimental Design and Reproducibility in Preclinical Animal Studies. Volume 1 in Laboratory Animal Science and Medicine series – Editors: José M. Sánchez-Morgado, Aurora Brønstad – Published 1 September 2021, ISBN 978-3-030-66147-2

22 Animal and environmental factors that influence reproducibility in Book: Experimental Design and Reproducibility in Preclinical Animal Studies Authors: José M. Sánchez-Morgado, Aurora Brønstad and Kathleen Pritchett-Corning – Published 1 September 2021

23 Good anesthesia practice for fish and aquatic animals – Aurora Brønstad, invited author til Tidskriftet: Biology, Manuscript ID: biology-1817638

 

Presentasjoner på møter og konferanser

2022

  • FISHends/FISHends-DIG project to improve humane endpoints in fish studies, Focus on Fish, RSPCA, online event February 23 2022
  • Learn From The Hoard - Fishends/fishends-dig Refinement Of Endpoints In Fish Studies, abstract presentation, FELASA 2022, 13-16 June 2022
  • Expanding the toolbox and stories to share – Animal Assisted Therapy learning by doing, presentasjon,  Fjärde Nordiska Seminariet om Hästunderstödda insatser. 17 September, Drotningsholm, Sverige

2021

  • FishENDS-Dig: IT-assisted refinement of fish welfare assessment and humane endpoints, Nordic 3R webinar, 5-6 May 2021

2020

  • Establishing score sheets and defining endpoints in fish experiments. Bergen Norway January 28 2020

2019

  • Humane endpoint – Concept and misconceptions, oral presentation at 14th FELASA congress 2019, Prague, Check Republic 10-13 June 2019
  • https://journals.sagepub.com/doi/full/10.1177/0023677219839199
  • Severity and humane endpoints in fish research, Bergen Norway October 4, 2019
  • Classification and reporting of severity of procedures, FELASA Workshop, Bergen, Norway, October 3 2019
  • Harm-Benefit analysis. The AAALAS-FELASA Working group approach -   at the Mouse genome engineering Course, August 26 2019, Dresden, Germany
  • How to perform literature searches and systematic reviews- at the “Are you PREPARED? How to design animal experiments”
  • 17 September 2019, NTNU
  • Harm-Benefit analysis. The AAALAS-FELASA Working group approach STOCKHOLM 26 September 2019. “Design of animal experiments” workshop on harm-benefit assessment
  • Introduction and Humane endpoints at Severity and humane endpoints in fish research, Bergen Norway, October 4 2019

 

2018

  • Harm-Benefit Assessment and Public Summary Master Course in Laboratory Animal Science and Welfare, Universitat Autònoma de Barcelona, Spain April 16-21, 2018,
  • Harm-Benefit analysis - Current concepts and practical approaches, Scand-LAS 2018 Symposium, Kristiansand Norway April 28 2018
  • The change of roles in the veterinary profession: Poster presentasjon World Association for the History of Veterinary Medicine Conference Bergen Norway June 7-9 2018
  • The art of comparing apples and oranges – Proposal from the AALAS - FELASA working group on harm-benefit analysis of animal studies. Poster presentation, World Association for the History of Veterinary Medicine Conference Bergen Norway June 7-9 2018
  • NENT 26 september 2018 – innspill til nye retningslinjer
  • Harm-Benefit analysis. The AAALAS-FELASA Working group approach STOCKHOLM 27 September “design of animal experiments” workshop on harm-benefit assessment
  • ESLAV-ECLAM-AAALAC-SECAL conference.” Typical Findings and Quality Expectations for Ethical Review and Oversight. The AAALAC Experience” Barcelona, Spain October 15-16 2018

2017

  • Harm-Benefit Analysis, Charles river short course 22-24 March 2017 Berlin Germany
  • How to inegrate severity calsification into Harm-Benefit Analysis, Severity Classification of Animal Procedures 29-30 June 2017 FGB Conference Centre, Varese Italy
  • Harm-Benefit analysis. The AAALAS-FELASA Working group approach -   at the Mouse genome engineering Course, 10 July 2017, Dresden, Germany

2016

  • Harm-Benefit Analysis: An Ethical Framework for conducting Humane Animal Research Update from the WG on Harm-Benefit Analysis, oral presentation, TT2016 Prague, March 22, 2016, Check Republic
  • Harm-Benefit Analysis: the AALAS-FELASA Working Group  proposal FELASA meeting June 16, 2016, Brussels, Belgium

2015

  • Harm-Benefit Assessment and non-technical project summaries (lectures) The UAB Master in Laboratory Animal Science & Welfare, Universitat Autonoma de Barcelona, Spain March 19 2015
  • Harm-Benefit Analysis - Update from the WG on Harm-Benefit Analysis. Animal welfare body workshop, Max Delbrück Center for Molecular Medicine – Berlin, Germany. September 25, 2015

2014

  • Harm-Benefit Analysis: An Ethical Framework for conducting Humane Animal Research Update from the WG on Harm-Benefit Analysis, (Workshop) 65 AALAS National Meeting, October 2014, San Antonio, Texas, USA
  • Harm-Benefit Analysis: An Ethical Framework for conducting Humane Animal Research Update from the WG on Harm-Benefit Analysis, (oral presentation) ebruary 14, 2014, Charles River Short Course, Strasbourg, France

2013

  • Humane endpoints, (lecture) FELASA C course, May 5, 2013, OSLO NVH, Norway
  • Workshop: Planning an efficient animal imaging unit, at 12the 2013 FELASA-SECAL Congress, Barcelona, Spain
  • Humane endpoints, (lecture) FELASA C course, oct 18 2013 OSLO NVH, Norway
  • Harm-Benefit Analysis: An Ethical Framework for conducting Humane
  • Animal Research Update from the WG on Harm-Benefit Analysis, Colorado State University, October 25, 2013. Fort Collins, Colorado USA
  • Harm-Benefit Analysis: An Ethical Framework for conducting Humane
  • Animal Research Update from the WG on Harm-Benefit Analysis, (oral presentation) 64 AALAS National Meeting, October 30, 2013, Baltimore, USA
  • Humane endpoints, (lecture) FELASA C course, nov18 2013, NTNU, Trondheim, Norway

2012

  • 3R, 3R culture and compliance with the 3R concept. Scand-LAS, Hell, Norway April 26-29, 2012 (oral)
  • A description of the Human-Animal bond found in different context: its impact on human and animal welfare. Berg AGT, Brønstad AM, Enmarker IC.  Scand-LAS, Hell, Norway April 26-29, 2012 (poster)

2011

  • Humane endpoints, (lecture) FEALASA C course, May 6, 2011, Tromsø, Norway
  • Ethical evaluation and project authorization in Norway, (oral), Scand-LAS, May 25*28 2011 Copenhagen, Denmark
  • The use of activity maps in project authorization (poster) 8th World Conference on Alternatives and Animal Use in Life Science August 21-25 2011, Montreal, Canada
  • Control of workstations and gas anesthesia equipment for rodents (poster) ESLAV-ECLAM-ILAF meeting: What´s New? Animal models, Housing and Techniques. Jerusalem, Israel, September 5-6, 2011
  • How does repeated anaesthesia effect on animals: physiological and welfare aspects - Challenges of Live Animal Imaging Facilities NorIMM, Turku Finland September 26-27, 2011
  • Bruk av score-sheet og aktivitetskart og hvordan utfyller disse hverandre? Kurs for ansvarshavende I regi av Forsøksdyrutvalget Oslo, Norway november 9 2011
  • Pig in research and Pig Anesthesia. NTNU, Trondheim, Norway November 25, 2011
  • Humane endpoints, (lecture) FELASA C course, May 6, 2011, OSLO NVH, Norway

2009

  • “Norecopa Norway´s consensus platform for replacement, reduction and refinement of animals experiments “at ‘Towards a common understanding of the meaning of the 3Rs' 22 &23 January 2009 Vilvorde KursusCenter, Denmark (poster + oral presenation)
  • COST B24 Lausanne Sveits, 16-17 April 2009 10 WG-meeting, Refinement, Reduction and animals imaging, Submittet to Cost B24 manual
  • Harmonisation of the Care and Use of Fish in Research, ” The challenge of arranging accredited courses for fish researchers and technicians” Gardermoen, Oslo, Norway, September 24 2009 (lecture)
  • 3R award 2009, Novo Nordisk, Denmark. Lecture: Implementing 3R – the human factor in an organizational theory perspective” (lecture)
  • Laboratory Animal Science for inspectors of the Food safety Authority in Norway October 30, 2009, Bergen Norway
  • Humane endpoints, (lecture) FEALASA C course, November 23, 2009, Trondheim, Norway
  • Experimental Physiology at University of Bergen, NorIMM research training course, November 25, 2009, Bergen Norway

2008

  • “How to make scientists compliant to research protocol”. Anne-Grethe T. Berg1, Aurora M. Brønstad2 & Lisbeth Ø. Rygg1 1Department of Health Science, Nord-Trøndelag University College, Namsos, Norway 2 Animal facilities, Facilty of medicine and dentistry, Bergen,Norway, at Scand-Las meeting Tartu, Estonia 8-11 may 2008 (poster)
  • Peri-anesthetic challenges in small animal imaging, BCCR 23-24 May 2008, Solstrand-Os, Norway (oral presentation)
  • Technology and philosophy – surveillance and handling in an animal’s welfare perspective, Scanbur 10th International Symposium, June 11-12 2008, Køge, Denmark (oral presentation)
  • Humane endpoints, (lecture) FEALASA C course, November 26, 2008, Trondheim, Norway

2007

  • ESLAV Courses in Laboratory Animal Science for Fish Researchers (poster) Cernobbio, Italy June 10-11, 2007
  • Magnet resonance Imaging for small laboratory animals. Lecture International course 26-27 November 2007, Vilnius, Litauen

2006

  • Establishing a national platform for alternatives to use of animals (oral presentation) October 18, 2006, Oslo Norway

2005

  • Bergen Conference on Cancer Research, Solstrand Bergen 20-21 mai 2005 magnetic resonance imaging (mri) of small laboratory animals – a new option at vivarium – University of Bergen” (oral presentation)

2002

  • 22nd Meeting of the European Society for Microcirculation: Exeter, UK, 28-30 aug 2002 “the effect of the taxanes; paclitaxel and docetaxel; and cremophor –el on edema formation and interstitial fluid pressure” A Brønstad, A Berg, RK Reed. (poster)

2001

  • Joint Congress of the Ger. & and Scand. Phys.Socs, Berlin 10-13 March 2001, ”Phalloidin inhibits the fall in interstitial fluid pressure and edema formation in rat paw skin normally asso

ciated with dextran anaphylaxis” A Brønstad, A Berg, A Reith, RK Reed. (poster)

2000

  • British Society of Matrix Biology (BSMB) London UK, 3-4 April 2000 “Measurement of interstitial fluid pressure in the rat paw skin after chemical modification of cytoskeletal proteins.” A.Berg, A.Reith, A.Brønstad, RK Reed (poster)
  • NorFAs Søndenborg Danmark 17-21 juni 2000, ”Internordic course on the regulation of vascular structure and function” (poster)
  • Scand.Phys.Soc.& Am.Phys.Soc. Joint Meeting, Stockholm Sweden 16-19 August 2000 “differences in interstitial fluid pressure in the trachea of rats from different strains” EAB Gjerde, DM Eide, A Brønstad, RK Reed (poster)

DVM PhD