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  • E-mailAurora.Martinez@uib.no
  • Phone+47 55 58 64 27
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen

Aurora Martinez is the leader of the research group Biorecognition that studies the relation between biomolecular structure and function to understand and develop new therapeutic options for genetic diseases, notably neurometabolic disorders such as phenylketonuria (PKU) and defects in dopamine synthesis.

Aurora is also a partner in the KG Jebsen Centre for neuropsychiatric disorders. In addition, she is also a partner in the project 'Molecular control of Arc protein: Decoding a master regulator of synaptic plasticity and cognition', coordinated by Clive Bramham, which received support from the Toppforsk Program (NFR).

  • Van Vliet, Danique; van der Goot, Els; van Ginkel, Wiggert G; van Faassen, Martijn H J R; de Blaauw, Pim; Kema, Ido P.; Martinez, Aurora; Heiner-Fokkema, M Rebecca; van der Zee, Eddy A; van Spronsen, Francjan J. 2019. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine-Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult Pah-Enu2 Mice. Nutrients.
  • Van Vliet, Danique; van der Groot, Els; van Ginkel, Wiggert G; van Faassen, Martijn H J R; Blaauw, Pim; Kema, Ido P.; Martinez, Aurora; Heiner-Fokkema, Rebecca; van der Zee, Eddy A; van Spronsen, Francjan J. 2019. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine- Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult Pah-Enu2 Mice. Nutrients.
  • Flydal, Marte Innselset; Alcorlo-Pagés, Martin; Johannessen, Fredrik Gullaksen; Martínez-Caballero, Siseth; Skjærven, Lars; Fernandez-Leiro, Rafael; Martinez, Aurora; Hermoso, Juan A. 2019. Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proceedings of the National Academy of Sciences of the United States of America. 11229-11234.
  • K C, Kunwar Jung; Himmelreich, Nastassja; Prestegård, Karina Skjervheim; Shi, Tie-Jun; Scherer, Tanja; Ying, Ming; Jorge Finnigan, Ana; Thöny, Beat; Blau, Nenad; Martinez, Aurora. 2019. Phenylalanine hydroxylase variants interact with the co-chaperone DNAJC12. Human Mutation. 483-494.
  • Ji, Jianxiong; Xu, Ran; Ding, Kaikai; Bao, Guoqing; Zhang, Xin; Huang, Bin; Wang, Xinyu; Martinez, Aurora; Wang, Xiuying; Li, Gang; Miletic, Hrvoje; Thorsen, Frits; Bjerkvig, Rolf; Xiang, Lei; Han, Bo; Chen, Anjing; Li, Xingang; Wang, Jian. 2019. Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-kappa B Signaling. Clinical Cancer Research. 6868-6881.
  • Brennecke, Philip; Rasina, Dace; Aubi Catevilla, Oscar; Herzog, Katja; Landskron, Johannes; Cautain, Bastien; Vicente, Francisca; Quintana, Jordi; Mestres, Jordi; Stechmann, Bahne; Ellinger, Bernhard; Brea, Jose; Kolanowski, Jacek L.; Pilarski, Radosław; Orzáez, Mar; Pineda-Lucena, Antonio; Laraia, Luca; Nami, Faranak; Zielenkiewicz, Piotr; Paruch, Kamil; Hansen, Espen; von Kries, Jens P.; Neuenschwander, Martin; Specker, Edgar; Bartunek, Petr; Šímová, Šárka; Leśnikowski, Zbigniew; Krauss, Stefan; Lehtiö, Lari; Bilitewski, Ursula; Brönstrup, Mark; Tasken, Kjetil; Jirgensons, Aigars; Lickert, Heiko; Clausen, Mads H.; Andersen, Jeanette hammer; Vicent, Maria J.; Genilloud, Olga; Martinez, Aurora; Nazaré, Marc; Fecke, Wolfgang; Gribbon, Philip. 2019. EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology. SLAS Discovery. 398-413.
  • Heggland, Erna Irene; Eichner, Christiane; Støve, Svein Isungset; Martinez, Aurora; Nilsen, Frank; Dondrup, Michael. 2019. A scavenger receptor B (CD36)-like protein is a potential mediator of intestinal heme absorption in the hematophagous ectoparasite Lepeophtheirus salmonis. Scientific Reports. 1-14.
  • Bustad, Helene J.; Toska, Karen; Schmitt, Caroline; Vorland, Marta; Skjærven, Lars; Kallio, Juha Pekka; Simonin, Sylvie; Lettéron, Philippe; Underhaug, Jarl; Sandberg, Sverre; Martinez, Aurora. 2019. A Pharmacological Chaperone Therapy for Acute Intermittent Porphyria. Molecular Therapy.
  • Bezem, Maria Teresa; Johannessen, Fredrik Gullaksen; K C, Kunwar Jung; Gundersen, Edvin Tang; Jorge Finnigan, Ana; Ying, Ming; Betbeder, Didier; Herfindal, Lars; Martinez, Aurora. 2018. Stabilization of Human Tyrosine Hydroxylase in Maltodextrin Nanoparticles for Delivery to Neuronal Cells and Tissue. Bioconjugate chemistry. 493-502.
  • Støve, Svein Isungset; Jorge-Finnigan, Ana; K C, Kunwar Jung; Martinez, Aurora. 2018. Regulation of protein-protein interactions crucial for dopamine synthesis.

More information in national current research information system (CRIStin)

Research groups