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  • E-mailDonald.Gullberg@uib.no
  • Phone+47 55 58 63 32
  • Visitor Address
    Department of Biomedicine
    Jonas Lies vei 91
    N-5009 Bergen
    Room 
    7A127aY
  • Postal Address
    Postboks 7804
    5020 Bergen

Molecular mechanisms of cell adehsion

The Gullberg laboratory has characterized the integrin α11β1, which is expressed on subsets of normal fibroblasts and on carcinoma-associated fibroblasts. Cells lacking α11β1 display disturbed cell-collagen interactions, altered metalloproteinase synthesis and reduced cell proliferation. Major projects within the group aim to further understand the role of this collagen receptor and other fibroblast integrins during health and in disease.

  • Show author(s) (2022). Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker? Journal of cell communication and signaling.
  • Show author(s) (2022). Integrin α11β1 and syndecan-4 dual receptor ablation attenuates cardiac hypertrophy in the pressure overloaded heart. American Journal of Physiology. Heart and Circulatory Physiology. H1057-H1071.
  • Show author(s) (2021). Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and obtustatin. Toxicology and Applied Pharmacology.
  • Show author(s) (2021). Role of evolutionary conserved residues in integrin α11 cytoplasmic tail.
  • Show author(s) (2021). Collagen assembly at the cell surface: dogmas revisited. Cells. 1-22.
  • Show author(s) (2020). Integrin α11β1 is a receptor for collagen XIII. Cell and Tissue Research.
  • Show author(s) (2020). Integrin Binding Dynamics Modulate Ligand-Specific Mechanosensing in Mammary Gland Fibroblasts. iScience.
  • Show author(s) (2020). Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase. Matrix Biology Plus.

More information in national current research information system (CRIStin)

1990 Phd Medical Chemistry, Uppsala University

1990-1992 Post Doc, Molecular Biology Institute, University of California Los Angeles

1993-2003 Researcher, Uppsala University

2004- today Professor, Department of Biomedicine, UoB

Research groups