• E-mailDonald.Gullberg@uib.no
  • Phone+47 55 58 63 32+47 928 04 941
  • Visitor Address
    Department of Biomedicine
    Jonas Lies vei 91
    N-5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen

Molecular mechanisms of cell adehsion

The Gullberg laboratory has characterized the integrin α11β1, which is expressed on subsets of normal fibroblasts and on carcinoma-associated fibroblasts. Cells lacking α11β1 display disturbed cell-collagen interactions, altered metalloproteinase synthesis and reduced cell proliferation. Major projects within the group aim to further understand the role of this collagen receptor and other fibroblast integrins during health and in disease.

  • Show author(s) 2020. Integrin α11β1 is a receptor for collagen XIII. Cell and Tissue Research.
  • Show author(s) 2020. Integrin Binding Dynamics Modulate Ligand-Specific Mechanosensing in Mammary Gland Fibroblasts. iScience.
  • Show author(s) 2020. Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase. Matrix Biology Plus.
  • Show author(s) 2019. Toward understanding scarless skin wound healing and pathological scarring [version 1; peer review: 2 approved]. F1000 Research.
  • Show author(s) 2019. Stromal integrin α11 regulates PDGFR-β signaling and promotes breast cancer progression. Journal of Clinical Investigation. 4609-4628.
  • Show author(s) 2019. Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes. The journal of pathology. Clinical research. 69-82.
  • Show author(s) 2019. Integrin alpha 11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation. Scientific Reports. 1-12.
  • Show author(s) 2019. Cancer-associated fibroblasts in desmoplastic tumors: emerging role of integrins. Seminars in Cancer Biology. 1-16.

More information in national current research information system (CRIStin)

1990 Phd Medical Chemistry, Uppsala University

1990-1992 Post Doc, Molecular Biology Institute, University of California Los Angeles

1993-2003 Researcher, Uppsala University

2004- today Professor, Department of Biomedicine, UoB

Research groups