• E-mailDonald.Gullberg@uib.no
  • Phone+47 55 58 63 32+47 928 04 941
  • Visitor Address
    Department of Biomedicine
    Jonas Lies vei 91
    N-5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen

Molecular mechanisms of cell adehsion

The Gullberg laboratory has characterized the integrin α11β1, which is expressed on subsets of normal fibroblasts and on carcinoma-associated fibroblasts. Cells lacking α11β1 display disturbed cell-collagen interactions, altered metalloproteinase synthesis and reduced cell proliferation. Major projects within the group aim to further understand the role of this collagen receptor and other fibroblast integrins during health and in disease.

  • Show author(s) (2023). Novel roles for cooperating collagen receptor families in fibrotic niches. Current Opinion in Cell Biology.
  • Show author(s) (2023). Matrix Stiffness-dependent Regulation of Integrin α11β1 Expression.
  • Show author(s) (2023). Forward genetics and functional analysis highlight Itga11 as a modulator of murine psoriasiform dermatitis. Journal of Pathology. 184-197.
  • Show author(s) (2023). Ablation of integrin-mediated cell-collagen communication alleviates fibrosis. Annals of the Rheumatic Diseases. 1474-1486.
  • Show author(s) (2022). What does it take to be a collagen receptor? Matrix Biology.
  • Show author(s) (2022). Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis. Frontiers in Oncology. 17 pages.
  • Show author(s) (2022). Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker? Journal of cell communication and signaling. 649-660.
  • Show author(s) (2022). Integrin α11β1 and syndecan-4 dual receptor ablation attenuates cardiac hypertrophy in the pressure overloaded heart. American Journal of Physiology. Heart and Circulatory Physiology. H1057-H1071.

More information in national current research information system (CRIStin)

1990 Phd Medical Chemistry, Uppsala University

1990-1992 Post Doc, Molecular Biology Institute, University of California Los Angeles

1993-2003 Researcher, Uppsala University

2004- today Professor, Department of Biomedicine, UoB