Eivind Valen

Professor, Associate group leader at Sars Centre and NCMM

Announcements:

Press (mostly Norwegian):

Interviews (mostly Norwegian):

Panel debates (mostly Norwegian):

Video:

I teach BINF201: Introduction to Omics

Academic article

Show author(s) (2023). Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes. Diabetologia. 2226-2237.

Show author(s) (2022). Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore cDNA sequencing. Nature Methods.
Show author(s) (2022). Long-read single-molecule RNA structure sequencing using nanopore. Nucleic Acids Research (NAR). 11 pages.

Show author(s) (2021). Rapid genome editing by CRISPR-Cas9-POLD3 fusion. eLIFE. 28 pages.
Show author(s) (2021). ORFik: a comprehensive R toolkit for the analysis of translation. BMC Bioinformatics. 1-16.
Show author(s) (2021). Deep conservation of ribosome stall sites across RNA processing genes. NAR Genomics and Bioinformatics. 1-13.
Show author(s) (2021). CRISPR Genome Editing Made Easy Through the CHOPCHOP Website. Current Protocols in Bioinformatics.

Show author(s) (2020). Profiling of Small Ribosomal Subunits Reveals Modes and Regulation of Translation Initiation. Cell reports. 18 pages.
Show author(s) (2020). Intellectual disability in KATP channel neonatal diabetes. Diabetes Care. 526-533.
Show author(s) (2020). Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation. PLoS Genetics. 1-25.
Show author(s) (2020). Assessment of tumor suppressor promoter methylation in healthy individuals. Clinical Epigenetics. 1-15.

Show author(s) (2019). tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing. RNA: A publication of the RNA Society. 1229-1241.
Show author(s) (2019). Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR. BMC Genomics.
Show author(s) (2019). CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing. Nucleic Acids Research (NAR). W171-W174.
Show author(s) (2019). Accurate analysis of genuine CRISPR editing events with ampliCan. Genome Research. 843-847.

Show author(s) (2018). Shoelaces: An interactive tool for ribosome profiling processing and visualization. BMC Genomics. 6 pages.

Show author(s) (2017). Ribosome signatures aid bacterial translation initiation site identification. BMC Biology. 1-14.
Show author(s) (2017). REPARATION: ribosome profiling assisted (re-) annotation of bacterial genomes. Nucleic Acids Research (NAR).

Show author(s) (2016). Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature Communications.
Show author(s) (2016). CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering. Nucleic Acids Research (NAR).

Show author(s) (2015). Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell reports. 875-883.

Show author(s) (2014). Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nature Communications.

Lecture

Editorial

Show author(s) (2022). Nye CRISPR-metoder og mer presis presisjonsmedisin. Tidsskrift for Den norske legeforening.

Doctoral dissertation

Show author(s) (2019). Understanding translational landscapes through the footprints of ribosomes.

Poster

Show author(s) (2022). CRISPR-Cas9 T cell editing pipeline for Finnish founder diseases.

Academic literature review

Show author(s) (2022). Small Open Reading Frames, How to Find Them and Determine Their Function. Frontiers in Genetics.

Show author(s) (2021). Transcript Isoform-Specific Estimation of Poly(A) Tail Length by Nanopore Sequencing of Native RNA. Methods in molecular biology. 543-567.

CRISPR genome engineering

RNA Biology

Nanopore sequencing

Regulation of Translation