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Eva Gerdts's picture

Eva Gerdts

Professor, Member Norwegian Academy of Science & Letters
  • E-mailEva.Gerdts@uib.no
  • Phone+47 55 97 30 54+47 920 86 505
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen

Heart disease in women is the main focus of all our research. The research involves international partnerships in Italy, Germany and USA. Different projects focus on heart disease due to high blood pressure, obesity, autoimmune diseases and aortic valve stenosis. Our research has so far contributed to the publication of European recommendations for treatment of high blood pressure in patients with aortic valve stenosis (2020) and a strong international focus on sex differences in heart disease through scientific publications, reviews and position papers in high-end journals including European Heart Journal, Nature Medicine and Hypertension. A new Centre for research on heart disease in women was established at UiB in June 2020 supported by Hjertefondet, Bergen Sanitetskvinner/Norske Kvinners Sanitetsforening and Grieg Foundation (https://www.uib.no/en/femaleheart). Our future research will be integrated with this new network.

The third survey in the Hordaland Health Study (HUSK3) is being performed from June 2018 until June 2022. The main focus is to explore the impact of change in blood pressure and other health factors when the participants were in their forties for cardiovascular health 20 years later. The HUSK3 project is a collaboration between 4 research groups at UiB chaired by Eva Gerdts, Grethe S. Tell, Ottar Nygård and Jutta Dierkes, the BEVITAL academic laboratory and professor Marjolein Iversen at the Western Norway University of Applied Sciences. Additional information may be found under: PhD student Ester A. Kringeland, UiB; PhD student Zoya Sabir, UiB

Uncontrolled high blood pressure is a major health challenge in Norway and a focus area for my research, in particular related to sex differences in how high blood pressure promote damage to the heart. From 2019 we participate in a new research collaboration between the 4 Norwegian Medical Faculties in Bergen, Oslo, Trondheim and Tromsø focusing on mechanisms for uncontrolled high blood pressure among patients who use blood pressure lowering drug treatment. This IDA study is funded by the Norwegian Research Council. At campus, we have also developed a local collaboration with consultant PhD Marianne Grytaas, Section for endocrinology, Haukeland University Hospital, Bergen, to study mechanisms of heart damage in patients with primary aldosteronism, a common cause of uncontrolled high blood pressure. In particular these studies will explore whether high blood pressure associated heart damage differs between women and men or depending on the etiology. See information on: PhD student Arleen Aune, UiB

Women with autoimmune diseases represent a high-risk group for development of premature heart disease. A research program on heart disease in autoimmune disorders have been developed in collaboration with national and international partners. From 2018 a research collaboration with Department of Rheumatology, Haukeland University Hospital has focused on the cardiac benefit of modern immunomodulating therapy for rheumatoid arthritis.  See information on: Postdoctoral fellow PhD Helga Midtbø, Haukeland University Hospital

A program targeting preclinical heart disease in young patients with ischemic stroke was initiated in 2012 in collaboration with professor Ulrike Waje-Andreassen, Department of Neurology, Haukeland University Hospital. The follow-up examinations will be completed in 2021. The program also includes an engagement from the Helsinki University Hospital to serve as echocardiography core laboratory in an European multicenter study in patients who suffer a cryptogenic stroke before the age of 50 years. See information on: Professor Ulrike Waje-Andreassen, UiB 

 

 

Academic article
  • Show author(s) 2019. Searching for explanations for cryptogenic stroke in the young: Revealing the Etiology, Triggers, and outcome (SECRETO): Echocardiography performance protocol. Echo Research and Practice. 53-61.
  • Show author(s) 2019. Prognostic impact of increased pulse pressure/stroke index in a registry of hypertensive patients: the Campania Salute Network. Blood Pressure. 268-275.
  • Show author(s) 2019. Long-term blood pressure trajectories and incident atrial fibrillation in women and men: the Tromsø Study . European Heart Journal. 1554-1562.
  • Show author(s) 2019. Left ventricular hypertrophy contributes to Myocardial Ischemia in Non-obstructive Coronary Artery Disease (the MicroCAD study). International Journal of Cardiology. 1-6.
  • Show author(s) 2018. Sex differences in subclinical cardiac disease in overweight and obesity (the FATCOR study). NMCD. Nutrition Metabolism and Cardiovascular Diseases. 1054-1060.
  • Show author(s) 2018. Prevalence and covariates of uncontrolled hypertension in ischemic stroke survivors: the Norwegian stroke in the young study. Blood Pressure. 173-180.
  • Show author(s) 2018. Left Ventricular Systolic Myocardial Function in Ankylosing Spondylitis . Arthritis care & research. 1276-1283.
  • Show author(s) 2018. Cardiac adaptation to hypertension in adult female Dahl salt-sensitive rats is dependent on ovarian function, but loss of ovarian function does not predict early maladaptation. Physiological Reports. 1-14.
  • Show author(s) 2018. Ankylosing spondylitis is associated with increased prevalence of left ventricular hypertrophy. Journal of Rheumatology. 1249-1255.
  • Show author(s) 2017. Small aortic root in aortic valve stenosis: clinical characteristics and prognostic implications. European Heart Journal-Cardiovascular Imaging. 404-412.
  • Show author(s) 2017. Masked hypertension in obesity: Potential predictors and arterial damage. Blood Pressure Monitoring. 12-17.
  • Show author(s) 2017. Lower transaortic flow rate is Associated with increased mortality in aortic valve stenosis. JACC Cardiovascular Imaging. 912-920.
  • Show author(s) 2017. Left ventricular hypertrophy regression during antihypertensive treatment in an outpatient clinic (the Campania salute network). Journal of the American Heart Association (JAHA). 1-16.
  • Show author(s) 2017. Influence of left ventricular stroke volume on incident heart failure in a population with preserved ejection fraction (from the Strong Heart Study). American Journal of Cardiology. 1047-1052.
  • Show author(s) 2017. Impact of stroke volume on cardiovascular risk during progression of aortic valve stenosis. Heart. 1443-1448.
  • Show author(s) 2017. Echocardiographic aortic valve calcification and outcomes in women and men with aortic stenosis. Heart. 1619-1624.
  • Show author(s) 2017. Does fitness improve the cardiovascular risk profile in obese subjects? NMCD. Nutrition Metabolism and Cardiovascular Diseases. 518-524.
  • Show author(s) 2017. Differential effect of obesity on prevalence of cardiac and carotid target organ damage in hypertension (the Campania Salute Network). International Journal of Cardiology. 260-264.
  • Show author(s) 2017. Comparison of frequency of ischemic cardiovascular events in patients with aortic stenosis with versus without asymmetric septal hypertrophy (from the SEAS Trial). American Journal of Cardiology. 1082-1087.
  • Show author(s) 2016. The association of hypertension with asymptomatic cardiovascular organ damage in rheumatoid arthritis. Blood Pressure. 298-304.
  • Show author(s) 2016. Prevalence and covariates of masked hypertension in ischemic stroke survivors: the Norwegian Stroke in the Young Study. Blood Pressure Monitoring. 244-250.
  • Show author(s) 2016. Higher pulse pressure/stroke volume index is associated with impaired outcome in hypertensive patients with left ventricular hypertrophy: the LIFE study. Blood Pressure. 150-155.
  • Show author(s) 2016. Giant right ventricular outflow tract thrombus in heriditary spherocytosis: a case report. Thrombosis Journal. 1-5.
  • Show author(s) 2016. Gender in cardiovascular diseases: Impact on clinical manifestations, management, and outcomes. European Heart Journal. 24-34.
  • Show author(s) 2016. Disease activity is associated with reduced left ventricular systolic myocardial function in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases. 371-376.
  • Show author(s) 2016. Covariates of non-dipping and elevated night-time blood pressure in ischemic stroke patients: the Norwegian Stroke in the Young Study. Blood Pressure. 212-218.
  • Show author(s) 2016. Aortic root dimension and arterial stiffness in arterial hypertension: The Campania Salute Network. Journal of Hypertension. 1109-1114.
  • Show author(s) 2015. Relation of Left Ventricular Mass to Prognosis in Initially Asymptomatic Mild to Moderate Aortic Valve Stenosis. Circulation Cardiovascular Imaging.
  • Show author(s) 2015. Obesity-associated metabolic changes influence resting and peak heart rate in women and men. Scandinavian Cardiovascular Journal. 337-343.
  • Show author(s) 2014. Adjusting parameters of aortic valve stenosis severity by body size. Heart. 1024-1030.
  • Show author(s) 2013. Natural history of mild and of moderate aortic stenosis-new insights from a large prospective European study. Current problems in cardiology. 365-409.
  • Show author(s) 2012. Inappropriately high left-ventricular mass in asymptomatic mild-moderate aortic stenosis. Journal of Hypertension. 421-428.
  • Show author(s) 2012. Impact of QRS duration and morphology on the risk of sudden cardiac death in asymptomatic patients with aortic stenosis the SEAS (Simvastatin and Ezetimibe in aortic stenosis) study. Journal of the American College of Cardiology. 1142-1149.
  • Show author(s) 2012. Hypertension in Aortic Stenosis Implications for Left Ventricular Structure and Cardiovascular Events. Hypertension. 90-97.
  • Show author(s) 2012. Association of heart failure hospitalizations with combined electrocardiography and ehocardiography criteria for left ventricular hypertrophy. American Journal of Hypertension. 678-683.
  • Show author(s) 2012. Arterial stiffness is associated with carotid atherosclerosis in hypertensive patients (The Campania Salute Network). American Journal of Hypertension. 739-745.
  • Show author(s) 2010. Left atrial size and force in patients with systolic chronic heart failure: Comparison with healthy controls and different cardiac diseases. Experimental and clinical cardiology. e45-e51.
  • Show author(s) 2009. Low-flow aortic stenosis in asymptomatic patients: valvular-arterial impedance and systolic function from the SEAS Substudy. JACC Cardiovascular Imaging. 390-399.
  • Show author(s) 2009. Clustered metabolic abnormalities blunt regression of hypertensive left ventricular hypertrophy: the LIFE study. NMCD. Nutrition Metabolism and Cardiovascular Diseases. 634-640.
  • Show author(s) 2008. Prevalence and covariates of electrocardiographic left ventricular hypertrophy in diabetic patients in Tanzania. Cardiovascular Journal of Africa. 8-14.
  • Show author(s) 2008. Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study. Journal of Hypertension. 1472-1476.
  • Show author(s) 2008. Clinical impact of ' in-treatment' wall motion abnormalities in hypertensive patients with left ventricular hypertrophy: the LIFE study. Journal of Hypertension. 806-812.
  • Show author(s) 2006. Impact of hypertension on left ventricular hypertrophy regression and exercise capacity in patients operated for aortic valve stenosis. Scandinavian Cardiovascular Journal. 167-174.
  • Show author(s) 2006. Impact of diabetes mellitus on regression of electrocardiographic left ventricular hypertrophy and the prediction of outcome during antihypertensive therapy - The Losartan Intervention for Endpoint (LIFE) Reduction in Hypertension Study. Circulation. 1588-1596.
  • Show author(s) 2005. Cardiovascular morbidity and mortality in hypertensive patients with a history of atrial fibrillation: The Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. Journal of the American College of Cardiology. 705-711.
  • Show author(s) 2005. Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. Journal of the American College of Cardiology. 712-719.
  • Show author(s) 2004. Usefulness of the assessment of the appropriateness of left ventricular mass to detect left ventricular systolic and diastolic abnormalities in absence of echocardiographic left ventricular hypertrophy: the LIFE study. Journal of Human Hypertension. 423-430.
  • Show author(s) 2004. Sex-related difference in regression of left ventricular hypertrophy with antihypertensive treatment: the LIFE study. Journal of Human Hypertension. 411-416.
  • Show author(s) 2004. Relation of impaired left ventricular filling to systolic midwall mechanics in hypertensive patients with normal left ventricular systolic chamber function: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study. American Heart Journal. 538-544.
  • Show author(s) 2004. Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol - The Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial. Circulation. 1456-1462.
  • Show author(s) 2004. Prognostic significance of left ventricular mass change during treatment of hypertension. Journal of the American Medical Association (JAMA). 2350-2356.
  • Show author(s) 2004. Impact of valvular regurgitation on left ventricular geometry and function in hypertensive patients with left ventricular hypertrophy: the LIFE study. Journal of Human Hypertension. 411-416.
  • Show author(s) 2004. Impact of age on left ventricular hypertrophy regression during antihypertensive treatment with losartan or atenolol (the LIFE study). Journal of Human Hypertension. 417-422.
  • Show author(s) 2004. Hypertensjon og hjertesykdom. Tidsskrift for Den norske legeforening. 802-805.
  • Show author(s) 2004. Essential hypertension in women. Blood Pressure. 272-278.
  • Show author(s) 2004. Effect of losartan versus atenolol on aortic valve sclerosis (a LIFE substudy). American Journal of Cardiology. 1076-1080.
  • Show author(s) 2004. Blood pressure measurements by the Keito machine. Evaluation versus office blood pressure by physicians. Blood Pressure Monitoring. 167-172.
  • Show author(s) 2004. Association of left bundle branch block with left ventricular structure and function in hypertensive patients with left ventricular hypertrophy: the LIFE study. Journal of Human Hypertension. 397-402.
  • Show author(s) 2004. Albuminuria predicts cardiovascular events independently of left ventricular mass in hypertension: a LIFE substudy. Journal of Human Hypertension. 453-459.
  • Show author(s) 2003. Pulse pressure/stroke index and left ventricular geometry and function:the Life Study. Journal of Hypertension. 781-787.
  • Show author(s) 2003. Left ventricular mass regression in the life study: effect of previous antihypertensive treatment. American Journal of Hypertension. 180-186.
  • Show author(s) 2003. Hjertesykdom ved genetisk hemokromatose. Hjerteforum. 16-20.
  • Show author(s) 2003. Echocardiographic wall motion abnormalities in hypertensive patients with electrocardiograaphhic left ventricular hypertrophy The life study. Hypertension. 75-82.
  • Show author(s) 2002. Urine albumin/creatinine ratio and echocardiographic left ventricular structure and function in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE study. Losartan Intervention for Endpoint Reduction. American Heart Journal. 319-326.
  • Show author(s) 2002. Sex differences in left ventricular systolic function. Cardiology Review. 29-32.
  • Show author(s) 2002. Relation of left ventricular geometry and function to aortic root dilatation in patients with systemic hypertension and left ventricular hypertrophy (the LIFE study). American Journal of Cardiology. 337-341.
  • Show author(s) 2002. Progressive hypertrophy regression with sustained pressure reduction in hypertension: the Losartan Intervention For Endpoint Reduction study. Journal of Hypertension. 1445-1450.
  • Show author(s) 2002. Impact of diastolic Doppler indices on exercise capacity in hypertensive patients with electrocardiographic left ventricular hypertrophy (a LIFE substudy). Journal of Hypertension. 1223-1229.
  • Show author(s) 2002. Correlates of pulse pressure reduction during antihypertensive treatment (losartan or atenolol) in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE study). American Journal of Cardiology. 399-402.
  • Show author(s) 2002. Correlates of left atrial size in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study. Hypertension. 739-743.
  • Show author(s) 2002. Change in systolic left ventricular performance after 3 years of antihypertensive treatment: the Losartan Intervention for Endpoint (LIFE) Study. Circulation. 227-232.
  • Show author(s) 2002. Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study. Circulation. 1071-1076.
  • Show author(s) 2002. Bruk av ekkokardiografi i hypertensjonsstudier. Hjerteforum. 77-83.
  • Show author(s) 2001. Similar effects of isolated systolic and combined hypertension on left ventricular geometry and function: the LIFE Study. American Journal of Hypertension. 768-774.
  • Show author(s) 2001. Renal hemodynamic effects of captopril and doxazosin during slight physical activity in hypertensive patients with type-1 diabetes mellitus. Kidney and Blood Pressure Research. 64-70.
  • Show author(s) 2001. Relation of left ventricular geometry and function to systemic hemodynamics in hypertension: the LIFE Study. Journal of Hypertension. 127-134.
  • Show author(s) 2001. Left ventricular function and hemodynamic features of inappropriate left ventricular hypertrophy in patients with systemic hypertension: the LIFE study. American Heart Journal. 784-791.
  • Show author(s) 2001. Gender differences in systolic left ventricular function in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE study). American Journal of Cardiology. 980-983.
  • Show author(s) 2001. Echocardiographic left ventricular geometry in hypertensive patients with electrocardiographic left ventricular hypertrophy: The LIFE Study. Blood Pressure. 74-82.
  • Show author(s) 2000. Long-term central hemodynamic effects at rest and during exercise of losartan in essential hypertension. American Heart Journal. 624-630.
  • Show author(s) 2000. Left ventricular wall stresses and stress-mass products in hypertensive patients with electrocardiographic left ventricular hypertrophy. Journal of Hypertension. 1129-1138.
  • Show author(s) 2000. Left ventricular wall stresses and stress-mass products in hypertensive patients with electrocardiographic left ventricular hypertrophy. Journal of Hypertension. 1129-1138.
  • Show author(s) 2000. Left ventricular diastolic filling patterns in hypertensive patients with electrocardiographic left ventricular hypertrophy: The LIFE Study. American Journal of Cardiology. 466-472.
  • Show author(s) 2000. Left ventricular diastolic filling patterns in hypertensive patients with electrocardiographic left ventricular hypertrophy: The LIFE Study. American Journal of Cardiology. 466-472.
  • Show author(s) 2000. Impact of different partition values on prevalences of left ventricular hypertrophy and concentric geometry in a large hypertensive population: the LIFE Study. Hypertension. 6-12.
  • Show author(s) 2000. Impact of different partition values on prevalences of left ventricular hypertrophy and concentric geometry in a large hypertensive population: the LIFE Study. Hypertension. 6-12.
  • Show author(s) 2000. HOPE ett år senere. Hjerteforum. 31-35.
  • Show author(s) 2000. HOPE ett år senere. Hjerteforum. 31-35.
  • Show author(s) 1999. Similar central hemodynamics in salt sensitive and salt resistant hypertensive patients. Blood Pressure. 233-241.
  • Show author(s) 1999. Reproducibility of salt sensitivity testing using a dictary approach in essential hypertension. Journal of Human Hypertension. 375-384.
  • Show author(s) 1999. Early complications and long-term mortality after urgent or routine coronary angioplasty. Scandinavian Cardiovascular Journal. 33.
  • Show author(s) 1998. The Bergen Blood pressure Study: changes in cardiac structure and function in offspring of hypertensive families. European Heart Journal. 474-474.
  • Show author(s) 1998. Is salt sensitivity a temporary phenomenon? Journal of Hypertension. 150-150.
  • Show author(s) 1998. Gender differences in systolic left ventricular function in hypertensive patients with electrocardiographic left ventricular hypertrophy. The LIFE. Circulation. 1-205.
  • Show author(s) 1998. Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using captopril or doxazosin for months months. American Journal of Hypertension. 1178-1187.
  • Show author(s) 1998. Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using Captopril or Doxazosin for months. American Journal of Hypertension. 1178-1187.
  • Show author(s) 1998. Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using Captopril or Doxazosin for months. American Journal of Hypertension. 1178-1187.
  • Show author(s) 1998. Factors Influencing Left Ventricular Mass in Salt Sensitive and Salt Resistant Essential Hypertensive Patients. Blood Pressure. 223-230.
  • Show author(s) 1998. Beta-2 adrenoceptor genetic variation is associated with genetic predisposition to essential hypertension: The Bergen Blood Pressure Study. Kidney International. 1455-1460.
  • Show author(s) 1997. Regression of left ventricular hypertrophy in type-1 diabetic patients using doxazosin as antihypertensive therapy @<abstract@>. Journal of Hypertension. 40.
  • Show author(s) 1997. Factors influencing LVM in hypertensitive type-1 diabetic patients. Blood Pressure. 197-202.
  • Show author(s) 1997. Factors influencing LVM in hypertensitive type-1 diabetic patients. Blood Pressure. 197-202.
  • Show author(s) 1997. Angiotensin converting enzyme inhibition and alpha<SUB>1</SUB>-receptor blockade as antihypertensive therapy in type-1 diabetic patients. American Journal of Hypertension. 121A.
  • Show author(s) 1996. Salt sensitivity in hypertensive type-1 diabetes mellitus. Blood Pressure. 78-85.
  • Show author(s) 1996. Salt sensitivity in hypertensive type-1 diabetes mellitus. Blood Pressure. 78-85.
  • Show author(s) 1996. Factors influencing left ventricular mass in hypertensive type-1 diabetic patients. American Journal of Hypertension. 65A.
  • Show author(s) 1994. Salt sensitive essential hyperdension evaluated by 24 hour ambulatory blood pressure. Blood Pressure. 375-380.
  • Show author(s) 1994. Salt sensitive essential hyperdension evaluated by 24 hour ambulatory blood pressure. Blood Pressure. 375-380.
  • Show author(s) 1994. Postoperative Doppler echocardiograpic evaluation in different sizes of Medtronic-Hall, Biocor and Carpentier-Edwards s.a.v. prosthetic-aortic valves. Scandinavian journal of thoracic and cardiovascular surgery. 25-29.
Academic lecture
  • Show author(s) 2018. Long-term systolic blood pressure trajectories predict risk of incident atrial fibrillation in a general population cohort study.
  • Show author(s) 2018. Long-term systolic blood pressure trajectories and incident atrial fibrillation in women and men: The Tromsø Study.
  • Show author(s) 2003. Left atrial size and risk of major cardiovascular events in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE trial).
  • Show author(s) 2002. The impact of concomitant diabtes on changes in left ventricular structure and function during antihypertensive treatment (the LIFE study).
  • Show author(s) 2002. Endocardial as well as midwll fractional shortening predict cardiovascular outcome in hypertension: The LIFE study.
  • Show author(s) 2001. Correlates of left atrial size in hypertensive patients with left ventricular hypertrophy: the LIFE study.
  • Show author(s) 2000. The effect of losartan treatment on left ventricular hypertrophy in patients with essential hypertension.
  • Show author(s) 2000. The effect of losartan treatment on left ventricular hypertrophy in patients with essential hypertension.
  • Show author(s) 2000. Reduction in left ventricular mass and blood pressure is not accompanied by improved exercise performance in hypertensive patients with left ventricular hypertrophy.
  • Show author(s) 2000. Reduction in left ventricular mass and blood pressure is not accompanied by improved exercise performance in hypertensive patients with left ventricular hypertrophy.
  • Show author(s) 2000. Parallel cardiac and renal damage in patients with left ventricular hypertrophy.
  • Show author(s) 2000. Parallel cardiac and renal damage in patients with left ventricular hypertrophy.
  • Show author(s) 2000. Inappropriate left ventricular mass is associated with high cardiovascular risk profile in hypertensive subjects.
  • Show author(s) 2000. Inappropriate left ventricular mass is associated with high cardiovascular risk profile in hypertensive subjects.
  • Show author(s) 2000. In hypertensive patients with left ventricular hypertrophy inappropriate left ventricular mass identifies high risk phenotypes.
  • Show author(s) 2000. In hypertensive patients with left ventricular hypertrophy inappropriate left ventricular mass identifies high risk phenotypes.
  • Show author(s) 2000. Change in diastolic left ventricular function after one year of antihypertensive treatment.
  • Show author(s) 2000. Change in diastolic left ventricular function after one year of antihypertensive treatment.
  • Show author(s) 2000. Antihypertensive therapy has greater impact on left ventrular hypertrophy reduction in women than men.
  • Show author(s) 2000. Antihypertensive therapy has greater impact on left ventrular hypertrophy reduction in women than men.
  • Show author(s) 1997. Hypertensive women with electrocardiographic left ventricular hypertrophy have Doppler echocardiographic indications of more impaired diastolic left ventricular function compared to men, at rest and during exercise.
  • Show author(s) 1996. Salt sensitivity in hypertensive type-1 diabetes mellitus.
  • Show author(s) 1996. Factors influencing left ventricular mass in hypertense type-1 diabetic patients.
  • Show author(s) 1995. Factors influencing the regression of left ventricular mass in men and women operated for aortic stenosis.
  • Show author(s) 1994. Plasma atial natriuretic peptide in salt sensitive hypertensive patients.
Abstract
  • Show author(s) 2020. Sex-specific temporal trends in the incidence of atrial fibrillation in a large Norwegian population-based study 1986–2014. European Heart Journal. 509-509.
  • Show author(s) 2020. Sex-specific temporal trends in the incidence of atrial fibrillation in a large Norwegian population-based study 1986-2014. European Heart Journal.
  • Show author(s) 2018. 6168 Long-term systolic blood pressure trajectories predict risk of incident atrial fibrillation in a general population cohort study. European Heart Journal. 1275-1276.
  • Show author(s) 2014. Determinants of left ventricular systolic function after transcatheter aortic valve implantation. European Heart Journal-Cardiovascular Imaging.
  • Show author(s) 2013. Outcome in 1763 asymptomatic patients with mild or moderate calcific aortic stenosis followed prospectively with annual echocardiography. European Heart Journal. 334-334.
  • Show author(s) 2013. Impact of isolated systolic hypertension on normalization of left ventricular structure during antihypertensive treatment in patients with electrocardiographic left ventricular hypertrophy (LIFE). European Heart Journal. 597-597.
  • Show author(s) 2013. Hypertensive target organ damage predicts incident diabetes mellitus. European Heart Journal. 3419-3426.
  • Show author(s) 2013. Does rheumatoid arthritis predispose to abnormal left ventricular geometry independent of hypertension? European Heart Journal. 754-754.
  • Show author(s) 2013. Disease Activity In Rheumatoid Arthritis Is Associated With Abnormal Left Ventricular Geometry. Arthritis and Rheumatism. S182-S182.
  • Show author(s) 2013. Coronary artery plaque burden is a predictor of myocardial ischemia in non-ST elevation myocardial infarction in both genders. European Heart Journal. 74-75.
  • Show author(s) 2013. Arterial Stiffness Is Associated With Abnormal Left Ventricular Geometry In Patients With Rheumatoid Arthritis. Arthritis and Rheumatism. S174-S175.
  • Show author(s) 2012. Midwall left ventricular systolic function in asymptomatic aortic valve stenosis: is it prognostically important? The SEAS study. European Heart Journal. 97-98.
  • Show author(s) 2012. Covariates of global longitudinal strain and displacement in type 2 diabetes: a speckle tracking echocardiography study. European Heart Journal. 454-454.
  • Show author(s) 2011. Increased systolic strain rate early after transcatheter aortic valve implantation. European Heart Journal-Cardiovascular Imaging. ii37-ii37.
  • Show author(s) 2011. Impact of valvuloarterial impedance on cardiovascular outcome in patients with asymptomatic aortic stenosis. The SEAS study. Circulation.
  • Show author(s) 2011. Impact of aortic valve stenosis and hypertension on radial strain in multiple layers. European Heart Journal, Supplement. 1008-1009.
  • Show author(s) 2010. Risk factors for unexpected sudden death in patients with non-symptomatic aortic stenosis (the SEAS study). European Heart Journal. 886-887.
  • Show author(s) 2010. Left ventricular mass, an independent predictor of morbidity and mortality in aortic valve stenosis. European Heart Journal. 887-887.
  • Show author(s) 2010. Increased Relative Wall Thickness - A Frequent Marker of Subclinical Cardiac Target Organ Damage in African Diabetic Patients. Journal of Hypertension. E357-E357.
  • Show author(s) 2010. Hypoperfusion by contrast echocardiography predicts coronary artery disease severity in non-ST elevation myocardial infarction. European Heart Journal. 914-914.
  • Show author(s) 2010. Hypokalemi blunts left ventricular mass regression in hypertensive patients during losartan- or atenolol-based treatmend: The LIFE echo-substudy. Journal of Hypertension. E442-E443.
  • Show author(s) 2010. COMBINED USE OF ELECTROCARDIOGRAM AND ECHOCARDIOGRAM TO BETTER IDENTIFY HYPERTENSIVE PATIENTS AT HIGH RISK FOR HEART FAILURE. Journal of Hypertension. E214-E214.
  • Show author(s) 2009. Relation of degree of aortic valve calcification to left ventricular geometry and systolic function in asymptomatic aortic valve stenosis: A SEAS substudy. Journal of the American College of Cardiology. A410-A410.
  • Show author(s) 2009. Outcome of Asymptomatic Patients With Low Gradient "Severe" Aortic Valve Stenosis and Preserved Ejection Fraction - Results From the Prospective SEAS Study. Circulation. S371-S371.
  • Show author(s) 2009. Impact of severity of aortic valve stenosis on effect of intensive lipid-lowering therapy: The SEAS study. Journal of the American College of Cardiology. A415-A415.
  • Show author(s) 2009. ISOLATED SYSTOLIC HYPERTENSION IN PATIENTS WITH ASYMPTOMATIC AORTIC STENOSIS (A SEAS SUBSTUDY). Journal of Hypertension. S248-S248.
  • Show author(s) 2009. IMPACT OF STROKE VOLUME ON CARDIOVASCULAR RISK IN HYPERTENSIVE PATIENTS WITH ELECTROCARDIOGRAPHIC LEFT VENTRICULAR HYPERTROPHY (A LIFE SUBSTUDY). Journal of Hypertension. S319-S320.
  • Show author(s) 2009. Gender Differences in Outcome During Antihypertensive Therapy in Relation to Regression of Electrocardiographic Left Ventricular Hypertrophy: The LIFE Study. Circulation. S1111-S1111.
  • Show author(s) 2009. Development of Systolic Dysfunction Not Related to Myocardial Infarction in Treated Hypertensive Patients With Left Ventricular Hypertrophy: The LIFE Echo Substudy. Circulation. S1164-S1165.
  • Show author(s) 2009. Compensatory or inappropriate left ventricular mass in asymptomatic aortic stenosis. Journal of the American College of Cardiology. A408-A409.
  • Show author(s) 2009. 2D Longitudinal Myocardial Strain: A More Sensitive Parameter of Left Ventricular Dysfunction in Aortic Valve Stenosis? Circulation. S372-S373.
  • Show author(s) 2008. The differential impact of static and pulsatile blood pressure components on regional myocardial deformation in patients with asymptomatic aortic valve stenosis. A SEAS substudy. Journal of Hypertension. S255-S256.
  • Show author(s) 2008. Impact of global afterload on left ventricular myocardial contractility in asymptomatic aortic stenosis: A SEAS substudy. Journal of the American College of Cardiology. A380-A380.
  • Show author(s) 2008. Impact of Pressure Recovery on Diagnosis of Severe Aortic Stenosis In Asymptomatic Patients. (A SEAS Substudy). Circulation. S931-S931.
  • Show author(s) 2008. Gender differences in left ventricular structure and function during antihypertensive treatment (the LIFE study). Journal of Hypertension. S275-S275.
  • Show author(s) 2007. Relationship of left ventricular Systolic function to persistence or development,of Electrocardiographic left ventricular hypertrophy in hypertensive patients: Implications for the development of new heart failure. Circulation. 473-473.
  • Show author(s) 2007. Pulse pressure - An independent predictor of left ventricular hyperthrophy in patients with asymptomatic aortic stenosis. A SEAS substudy. Circulation. 671-671.
  • Show author(s) 2007. Mitral E wave deceleration time to peak E velocity ratio and cardiovascular outcome in hypertensive patients during anti-hypertensive treatment: The LIFE echo-substudy. Circulation. 498-498.
  • Show author(s) 2007. Impact of left ventricular geometry on stress-corrected left ventricular systolic function in asymptomatic aortic valve stenosis. A SEAS substudy. Journal of the American College of Cardiology. 298A-299A.
  • Show author(s) 2007. Gender difference in the association of aortic valve sclerosis and cardiovascular events in hypertensive adults with left ventricular hypertrophy: The LIFE study. Circulation. 735-735.
  • Show author(s) 2007. Does metabolic syndrome influence reduction of ECG left ventricular hypertrophy? The LIFE study. Journal of Hypertension. S78-S78.
  • Show author(s) 2007. Association of aortic regurgitation with cardiovascular morbidity and mortality in hypertensive patients with left ventricle hypertrophy: The LIFE study. Circulation. 735-735.
  • Show author(s) 2006. Relationship of left atrial enlargement to persistence or development of electrocardiographic left ventricular hypertrophy in hypertensive patients: implications for the development of new atrial fibrillation. Circulation. 366-366.
  • Show author(s) 2006. Prevalence and covariates of low left ventricular midwall shortening in patients with asymptomatic aortic valve stenosis. A SEAS substudy. Circulation. 656-657.
  • Show author(s) 2006. Impact of gender on left atrial and ventricular response to asymptornatic aortic valve stenosis. The SEAS study. Journal of the American College of Cardiology. 285A-286A.
  • Show author(s) 2005. Relationship of electrocardiographic strain pattern to left ventricular diastolic function in hypertensive patients: The LIFE study. Journal of the American College of Cardiology.
  • Show author(s) 2005. Influence of hypertension on angiographic findings in patients with angina pectoris. American Journal of Hypertension. 175A.
  • Show author(s) 2005. Impact of concomitant hypertension on left ventricular structure in patients with aortic valve stenosis. The SEAS study. European Heart Journal-Cardiovascular Imaging. S76.
  • Show author(s) 2005. Echocardiographic determinants of new-onset atrial fibrillation in patients with hypertension and electrocardiographic left ventricular hypertrophy: The LIFE study. Journal of the American College of Cardiology.
  • Show author(s) 2004. Tissue Doppler findings in patients with genetic hemochromatosis. Hjerteforum. 101.
  • Show author(s) 2004. Pulse pressure as cardiovascular risk marker during losartan or atenolol based therapy in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE Trial). Journal of the American College of Cardiology. 448A.
  • Show author(s) 2004. Myocardial performance index independently predicts cardiovascular morbidity and mortality in hypertensive patients with electrocardiographic left ventricular hypertrophy: The LIFE Study. Journal of the American College of Cardiology. 227A.
  • Show author(s) 2004. Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: The LIFE Study. Journal of the American College of Cardiology. 357A.
  • Show author(s) 2004. Ethnicity, left ventricular hypertrophy regressio and cardiovascular events in the LIFE echocardiography substudy. American Journal of Hypertension. A195.
  • Show author(s) 2004. Does losartan improve diastolic left ventricular function beetter than atenolol during more then four years of antihypertensive treatment? The LIFE Study. Circulation. 637.
  • Show author(s) 2004. Clinical and echocardiographic risk factors for congestive heart failure in controlled hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE Study). Circulation. 682-682.
  • Show author(s) 2004. Blood pressure and cardiovascular risk factors in hypertensive patients referred to a regional hospital in Ghana. American Journal of Hypertension. A196.
Academic literature review
  • Show author(s) 2021. Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: Position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart. Cardiovascular Research (CVR). 367-385.
  • Show author(s) 2020. Management of patients with combined arterial hypertension and aortic valve stenosis: a consensus document from the Council on Hypertension and Council on Valvular Heart Disease of the European Society of Cardiology, the European Association of Cardiovascular Imaging (EACVI), the European Association of Percutaneous Cardiovascular Interventions (EAPCI). European Heart Journal (EHJ) - Cardiovascular Pharmacotherapy.
  • Show author(s) 2019. Sex differences in cardiometabolic disorders. Nature Medicine. 1657-1666.
  • Show author(s) 2018. Managing complications of hypertension in aortic valve stenosis patients. Expert Review of Cardiovascular Therapy. 897-907.
  • Show author(s) 2016. Epidemiology of left ventricular hypertrophy in hypertension: implications for the clinic. Expert Review of Cardiovascular Therapy. 915-926.
  • Show author(s) 2016. Atherosclerosis in Sjögren's syndrome: Evidence, possible mechanisms and knowledge gaps. Clinical and Experimental Rheumatology. 133-142.
  • Show author(s) 2013. Left ventricular geometry in obesity: Is it what we expect? NMCD. Nutrition Metabolism and Cardiovascular Diseases. 905-912.
  • Show author(s) 2010. Impact of ultrasound contrast agents in echocardiographic assessment of ischemic heart disease. Recent patents on cardiovascular drug discovery. 103-112.
  • Show author(s) 2004. Essential hypertension in women. Blood Pressure. 272-278.

More information in national current research information system (CRIStin)

FEMALE HEART project

International collaboration from 2012 with researchers at UiT The Arctic University of Norway and federico II University of Naples, Italy. Translational project involving experimental animal studies and clinical studies. The project aim to identify mechanisms for why high blood pressure is more damaging to the heart in women than in men. An annual Female Heart workshop is organized at UiB based on this collaboration. 

Hordaland Health Study - 3rd survey (HUSK3)

Focus on how blood pressure in 40 years old women and men predicts their cardiovascular health 20 years later. Follow up of 3000 individuals.

FAT associated cardiovascular dysfunction (FATCOR)

Focus on how obesity influences cardiac and arterial function in women and men. Crossectional study of 620 individuals.

The IDA study

Focuses on mechanisms for uncontrolled high blood pressure in patients who are perscribed antihypertensive drugs. Estimated 1000 participants. National Norwegian research project.

Sex differences and hypertension in aortic stenosis

Based upon 1873 patients with aortic valve stenosis who participated in the Simvastatin Ezetimibe in Aortic Stenosis (SEAS) study.