Home
Eystein Sverre Husebye's picture

Eystein Sverre Husebye

Professor, Vice Head of Institute. Consultant in endocrinology
  • E-mailEystein.Husebye@uib.no
  • Phone+47 55 97 30 78
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen

Addison's disease

Autoimmune polyendocrine disorders

Hypoparathyroidism

Endocrinology

Academic article
  • Show author(s) (2024). Regulatory T cells in autoimmune primary adrenal insufficiency. Clinical and Experimental Immunology. 47-57.
  • Show author(s) (2024). Improving diagnostic precision in primary ovarian insufficiency using comprehensive genetic and autoantibody testing. Human Reproduction. 177-189.
  • Show author(s) (2022). Screening patients with autoimmune endocrine disorders for cytokine autoantibodies reveals monogenic immune deficiencies. Journal of Autoimmunity. 1-?.
  • Show author(s) (2022). Pulsatile Subcutaneous Hydrocortisone Replacement in Primary Adrenal Insufficiency. Hormone and Metabolic Research. 471-478.
  • Show author(s) (2022). Prenatal dexamethasone treatment for classic 21-hydroxylase deficiency in Europe. European Journal of Endocrinology (EJE). K17-K24.
  • Show author(s) (2022). Premature menopause and autoimmune primary ovarian insufficiency in two international multi-center cohorts. Endocrine Connections. 11 pages.
  • Show author(s) (2022). Novel inflammatory biomarkers in thyroid eye disease. European Journal of Endocrinology (EJE). 293-300.
  • Show author(s) (2022). Fear of Covid 19 during the third wave of infection in Norwegian patients with type 1 diabetes. PLOS ONE. 1-13.
  • Show author(s) (2022). Extrathymic expression of Aire controls the induction of effective T<inf>H</inf>17 cell-mediated immune response to Candida albicans. Nature Immunology. 1098-1108.
  • Show author(s) (2022). Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline. European Journal of Endocrinology (EJE). G1-G21.
  • Show author(s) (2022). Current clinical practice for thromboprophylaxis management in patients with Cushing’s syndrome across reference centers of the European Reference Network on Rare Endocrine Conditions (Endo-ERN). Orphanet Journal of Rare Diseases. 12 pages.
  • Show author(s) (2022). Cardiometabolic Disease Burden and Steroid Excretion in Benign Adrenal Tumors A Cross-Sectional Multicenter Study. Annals of Internal Medicine. 325-334.
  • Show author(s) (2022). Autoimmune Thyroid Disorders in Autoimmune Addison Disease. Journal of Clinical Endocrinology and Metabolism (JCEM). e2331-e2338.
  • Show author(s) (2021). X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19. Science immunology.
  • Show author(s) (2021). Pregnancy Outcome in Women With APECED (APS-1): A Multicenter Study on 43 Females With 83 Pregnancies. Journal of Clinical Endocrinology and Metabolism (JCEM).
  • Show author(s) (2019). HbA1c predicts long-term postoperative mortality in patients with unknown glycemic status at admission for vascular surgery: An exploratory study. Journal of Diabetes.
  • Show author(s) (2018). Assay of steroids by liquid chromatography-tandem mass spectrometry in monitoring 21-hydroxylase deficiency. Endocrine Connections. 1542-1550.
  • Show author(s) (2017). Simultaneous assay of cortisol and dexamethasone improved diagnostic accuracy of the dexamethasone suppression test. European Journal of Endocrinology (EJE). 705-713.
  • Show author(s) (2017). Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1. Autoimmunity. 223-231.
  • Show author(s) (2017). Expanding the Phenotypic and Genotypic Landscape of Autoimmune Polyendocrine Syndrome Type 1. Journal of Pediatric Endocrinology & Metabolism (JPEM). 3546-3556.
  • Show author(s) (2017). Clues for early detection of autoimmune Addison's disease - myths and realities. Journal of Internal Medicine. 190-199.
  • Show author(s) (2017). Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population. Hormone and Metabolic Research. 838-846.
  • Show author(s) (2017). Autoantibody repertoire in APECED patients targets two distinct subgroups of proteins. Frontiers in Immunology.
  • Show author(s) (2017). Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins. Frontiers in Immunology.
  • Show author(s) (2016). Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1. Scientific Reports.
  • Show author(s) (2016). Epidemiology and health-related quality of life in hypoparathyroidism in Norway. Journal of Clinical Endocrinology and Metabolism (JCEM). 3045-3053.
  • Show author(s) (2016). Effect of a pre-exercise hydrocortisone dose on short-term physical performance in female patients with primary adrenal failure. European Journal of Endocrinology (EJE). 97-105.
  • Show author(s) (2016). Anticommensal responses are associated with regulatory T cell defect in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Journal of Immunology. 2955-2964.
  • Show author(s) (2016). Antibodies against NALP5 and it's role in hypoparathyroidism in autoimmune polyglandular syndrome type 1. Problemy Endokrinologii. 25-30.
  • Show author(s) (2016). Analysis of cellular and humoral immune responses against cytomegalovirus in patients with autoimmune Addison's disease. Journal of Translational Medicine.
  • Show author(s) (2016). Adrenal insufficiency therapy: How to keep the balance between good quality of life and low risk for long-term side effects? Frontiers of Hormone Research. 196-210.
  • Show author(s) (2016). Abdominal aortic aneurysms - glycaemic status and mortality. Journal of Diabetes and its Complications (JDC). 438-443.
  • Show author(s) (2016). A variant in the BACH2 gene is associated with susceptibility to autoimmune addison's disease in humans. Journal of Clinical Endocrinology and Metabolism (JCEM). 3865-3869.
  • Show author(s) (2016). A longitudinal follow-up of autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism (JCEM). 2975-2983.
  • Show author(s) (2015). Transglutaminase 4 as a prostate autoantigen in male subfertility. Science Translational Medicine.
  • Show author(s) (2015). The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nature Immunology. 737-745.
  • Show author(s) (2015). Peripheral blood cells from patients with autoimmune Addison's disease poorly respond to interferons in vitro, despite elevated serum levels of interferon-inducible chemokines. Journal of Interferon and Cytokine Research. 759-770.
  • Show author(s) (2015). Linkage analysis in autoimmune Addison's disease: NFATC1 as a potential novel susceptibility locus. PLOS ONE.
  • Show author(s) (2015). Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease - An association study and expression analysis. Autoimmunity. 100-107.
  • Show author(s) (2015). Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6. Endocrine Connections. 215-222.
  • Show author(s) (2015). En mann i 30-årene med diabetes og vitiligo. Tidsskrift for Den norske legeforening. 763-766.
  • Show author(s) (2015). Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity. 1185-1196.
  • Show author(s) (2015). Determination of 21-hydroxylase autoantibodies: Inter-laboratory concordance in the Euradrenal International Serum Exchange Program. Clinical Chemistry and Laboratory Medicine. 1761-1770.
  • Show author(s) (2015). Circadian hormone profiles and insulin sensitivity in patients with Addison's disease: a comparison of continuous subcutaneous hydrocortisone infusion with conventional glucocorticoid replacement therapy. Clinical Endocrinology. 28-35.
  • Show author(s) (2015). CTLA-4 as a genetic determinant in autoimmune Addison's disease. Genes and Immunity. 430-436.
  • Show author(s) (2014). The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease. Clinical and Experimental Immunology. 351-362.
  • Show author(s) (2014). High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients. Journal of Immunology. 2118-2126.
  • Show author(s) (2014). Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia. Endocrine Connections. 67-74.
  • Show author(s) (2014). Continuous subcutaneous hydrocortisone infusion versus oral hydrocortisone replacement for treatment of Addison's disease: A randomized clinical trial. Journal of Clinical Endocrinology and Metabolism (JCEM). 1665-1674.
  • Show author(s) (2014). Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency. Journal of Internal Medicine. 104-115.
  • Show author(s) (2014). Clinical and serologic parallels to APS-I in patients with thymomas and autoantigen transcripts in their tumors. Journal of Immunology. 3880-3890.
  • Show author(s) (2014). CYP21A2 polymorphisms in patients with autoimmune Addison's disease, and linkage disequilibrium to HLA risk alleles. European Journal of Endocrinology (EJE). 743-750.
  • Show author(s) (2014). Association of autoimmune Addison's disease with alleles of STAT4 and GATA3 in European Cohorts. PLOS ONE.
  • Show author(s) (2014). Altered DNA methylation profile in Norwegian patients with Autoimmune Addison's Disease. Molecular Immunology. 208-216.
  • Show author(s) (2014). A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. Clinical Immunology. 220-227.
  • Show author(s) (2013). Screening for X-linked adrenoleukodystrophy among adult men with Addison's disease. Clinical Endocrinology. 316-320.
  • Show author(s) (2013). BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Science Translational Medicine. 10 pages.
  • Show author(s) (2013). Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity. Immunobiology. 899-909.
  • Show author(s) (2013). Anti-cytokine autoantibodies preceding onset of autoimmune polyendocrine syndrome type I features in early childhood. Journal of Clinical Immunology. 1341-1348.
  • Show author(s) (2013). A candidate gene analysis of canine hypoadrenocorticism in 3 dog breeds. Journal of Heredity. 807-820.
  • Show author(s) (2012). Radioligand-binding assay reveals distinct autoantibody preferences for type I interferons in APS I and myasthenia gravis subgroups. Journal of Clinical Immunology. 230-237.
  • Show author(s) (2012). Quality of life in European patients with Addison's Disease: Validity of the disease-specific questionnaire AddiQoL. Journal of Clinical Endocrinology and Metabolism (JCEM). 568-576.
  • Show author(s) (2012). Genetic, anthropometric and metabolic features of adult Norwegian patients with 21-hydroxylase deficiency. European Journal of Endocrinology (EJE). 507-516.
  • Show author(s) (2012). Autoimmune polyendocrine syndrome Type 1: an Eetensive longitudinal study in Sardinian patients. Journal of Clinical Endocrinology and Metabolism (JCEM). 1114-1124.
  • Show author(s) (2011). TSGA10 – A target for autoantibodies in autoimmune polyendocrine syndrome Type 1 and systemic lupus erythematosus. Scandinavian Journal of Immunology. 147-153.
  • Show author(s) (2011). Multiple loci in the HLA complex are associated with Addison's Disease. Journal of Clinical Endocrinology and Metabolism (JCEM). E1703-E1708.
  • Show author(s) (2011). Measuring autoantibodies against IL-17F and IL-22 in Autoimmune Polyendocrine Syndrome Type I by radioligand binding assay using fusion proteins. Scandinavian Journal of Immunology. 327-333.
  • Show author(s) (2011). Hypoparathyroidism and autoimmunity in the 22q11.2 deletion syndrome. European Journal of Endocrinology (EJE). 345-352.
  • Show author(s) (2011). High frequency of adrenal myelolipomas and testicular adrenal rest tumours in adult Norwegian patients with classical congenital adrenal hyperplasia because of 21-hydroxylase deficiency. Clinical Endocrinology. 753-759.
  • Show author(s) (2011). Grapefruit juice and licorice increase cortisol availability in patients with Addison's disease. European Journal of Endocrinology (EJE). 761-769.
  • Show author(s) (2011). Genome-wide copy number variation (CNV) in patients with autoimmune Addison's disease. BMC Medical Genetics. 6 pages.
  • Show author(s) (2011). Cellular immunity and immunopathology in autoimmune Addison’s disease. Molecular and Cellular Endocrinology. 180-190.
  • Show author(s) (2010). Subjective health status in men and women with congenital adrenal hyperplasia: a population-based survey in Norway. European Journal of Endocrinology (EJE). 453-459.
  • Show author(s) (2010). Sexuality and Fertility in Women with Addison's Disease. Journal of Clinical Endocrinology and Metabolism (JCEM). 4354-4360.
  • Show author(s) (2010). Phenotypic Variation in a Large Family with Autosomal Dominant Hypocalcaemia. Hypertension in Pregnancy. 399-405.
  • Show author(s) (2010). Novel sequence variation of AIRE and detection of interferon-ω antibodies in early infancy. Clinical Endocrinology. 641-647.
  • Show author(s) (2010). Flow cytometry study of blood cell subtypes reflects autoimmune and inflammatory processes in autoimmune polyendocrine syndrome type I. Scandinavian Journal of Immunology. 459-467.
  • Show author(s) (2010). Development of a Disease-Specific Quality of Life Questionnaire in Addison's Disease. Journal of Clinical Endocrinology and Metabolism (JCEM). 545-551.
  • Show author(s) (2010). Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. Journal of Experimental Medicine (JEM). 299-308.
  • Show author(s) (2010). A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Annals of the Rheumatic Diseases. 1471-1474.
  • Show author(s) (2009). X-Linked Congenital Adrenal Hypoplasia with Hypogonadotropic Hypogonadism Caused by an Inversion Disrupting a Conserved Noncoding Element Upstream of the NR0B1 (DAX1) Gene. Journal of Clinical Endocrinology and Metabolism (JCEM). 4086-4093.
  • Show author(s) (2009). Two adults with adrenal myelolipoma and 21-hydroxylase deficiency. Clinical Medicine : Case Reports. 4 pages.
  • Show author(s) (2009). The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: The major autoantigen in autoimmune Addison's disease. Journal of Autoimmunity. 58-67.
  • Show author(s) (2009). Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 304-314.
  • Show author(s) (2009). T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency. Journal of Clinical Endocrinology and Metabolism (JCEM). 5117-5124.
  • Show author(s) (2009). Skin changes as diagnostic aid. Tidsskrift for Den norske legeforening. 752-752.
  • Show author(s) (2009). Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility. Journal of Clinical Endocrinology and Metabolism (JCEM). 5139-5145.
  • Show author(s) (2009). Programmed Death Ligand 1 (PD-L1) Gene Variants Contribute to Autoimmune Addison’s Disease and Graves’ Disease Susceptibility. Journal of Clinical Endocrinology and Metabolism (JCEM). 5139-5145.
  • Show author(s) (2009). Pathogenesis of primary adrenal insufficiency. Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism. 147-157.
  • Show author(s) (2009). Glucocorticoid replacement therapy and pharmacogenetics in Addison's disease: effects on bone. European Journal of Endocrinology (EJE). 993-1002.
  • Show author(s) (2009). Development of a Disease-Specific Quality of Life Questionnaire in Addison’s Disease. Journal of Clinical Endocrinology and Metabolism (JCEM).
  • Show author(s) (2009). Clinical, Immunological, and Genetic Features of Autoimmune Primary Adrenal Insufficiency: Observations from a Norwegian Registry. Journal of Clinical Endocrinology and Metabolism (JCEM). 4882-4890.
  • Show author(s) (2009). Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I. Journal of Internal Medicine. 514-529.
  • Show author(s) (2009). A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes. Genes and Immunity. 120-124.
  • Show author(s) (2009). A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-CCP negative rheumatoid arthritis. Annals of the Rheumatic Diseases.
  • Show author(s) (2008). Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clinical Immunology. 163-169.
  • Show author(s) (2008). Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. Journal of Clinical Endocrinology and Metabolism (JCEM). 3310-3317.
  • Show author(s) (2008). Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease. European Journal of Human Genetics. 977-982.
  • Show author(s) (2008). Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes. Blood. 2657-2666.
  • Show author(s) (2008). Autoimmune polyendocrine syndrome type I in Slovakia: relevance of screening patients with autoimmune Addison's disease. European Journal of Endocrinology (EJE). 705-709.
  • Show author(s) (2008). Autoimmune polyendocrine syndrome type 1 and NALP5, parathyroid autoantigen. New England Journal of Medicine. 1018-1028.
  • Show author(s) (2008). AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. Genes and Immunity. 130-136.
  • Show author(s) (2007). Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1. Proceedings of the National Academy of Sciences of the United States of America. 949-954.
  • Show author(s) (2007). Fc gamma receptor polymorphisms are not associated with autoimmune Addison's disease. Scandinavian Journal of Immunology. 555-558.
  • Show author(s) (2007). Epitope mapping of human aromatic L-amino acid decarboxylase. Biochemical and Biophysical Research Communications - BBRC. 692-698.
  • Show author(s) (2007). Continuous subcutaneous hydrocortisone infusion in Addison's disease. European Journal of Endocrinology (EJE). 109-112.
  • Show author(s) (2006). The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope. Endocrinology. 2411-2416.
  • Show author(s) (2006). Saliva cortisol measurement: simple and reliable assessment of the glucocorticoid replacement therapy in Addison's disease. Journal of Endocrinological Investigation. 727-731.
  • Show author(s) (2006). Detection of autoantibodies to the BTB-kelch protein KLHL7 in cancer sera. Scandinavian Journal of Immunology. 325-335.
  • Show author(s) (2006). Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Medicine. 1152-1164.
  • Show author(s) (2005). Primær binyrebarksvikt - årsaker, diagnostikk og behandling (=Primary adrenal failure - Causes, diagnostics and therapy). Tidsskrift for Den norske legeforening. 155-158.
  • Show author(s) (2005). Primær binyrebarksvikt - årsaker, diagnostikk og behandling. Tidsskrift for Den norske legeforening. 155-158.
  • Show author(s) (2005). CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Research. 55-58.
  • Show author(s) (2005). CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Research.
  • Show author(s) (2005). Autoantibodies to a NR2A peptide of the glutamate/NMDA receptor in sera of patients with systemic lupus erythematosus. Annals of the Rheumatic Diseases. 210-213.
  • Show author(s) (2004). Pyridoxal phosphatase is a novel cancer autoantigen in the central nervous system. British Journal of Cancer. 1508-1514.
  • Show author(s) (2004). Chronic mucocutaneous candidiasis and primary hypothyroidism in two families. European Journal of Pediatrics. 604-611.
  • Show author(s) (2004). Chronic mucocutaneous candidiasis and primary hypothyroidism in two families. European Journal of Pediatrics. 604-611.
  • Show author(s) (2004). Autoantibodies against 21-hydroxylase and side-chain cleavage enzyme in autoimmune Addison's disease are mainly immunoglobulin G1. European Journal of Endocrinology (EJE). 49-56.
  • Show author(s) (2004). Analysis of antibody reactivity against cysteine sulfinic acid decarboxylase, a pyridoxal phosphate-dependent enzyme, in endocrine autoimmune disease. Journal of Clinical Endocrinology and Metabolism (JCEM). 1636-1640.
  • Show author(s) (2003). Replacement therapy in Addison's disease. Expert Opinion on Pharmacotherapy. 2145-2149.
  • Show author(s) (2003). Replacement of Dehydroepiandrosterone in Adrenal Failure: No Benefit for Subjective Healt Status and Sexuality in a 9-Month, Randomized, Parallel Group Clinical Trial. Journal of Clinical Endocrinology and Metabolism (JCEM). 1112-1118.
  • Show author(s) (2003). Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells. Journal of Clinical Endocrinology and Metabolism (JCEM). 1445-1452.
  • Show author(s) (2003). High frequency of coeliac disease among patients with autoimmune adrenocortical failure. Scandinavian Journal of Gastroenterology. 511-515.
  • Show author(s) (2003). Døgnrytme til besvær. Tidsskrift for Den norske legeforening. 1858-1859.
  • Show author(s) (2002). Subjective health status in Norwegian patients with Addison's disease. Clinical Endocrinology. 581-588.
  • Show author(s) (2002). Predictors of outcome and comparison of different drug regimens for the prevention of relapse in patients with Graves' disease. European Journal of Endocrinology (EJE). 583-589.
  • Show author(s) (2002). Mutational analysis of the autoimmune regulator gene in sporadic autoimmune Addison`s disease can reveal patients with unidentified autoimmune polyendocrine syndrome type I. European Journal of Endocrinology (EJE). 519-522.
  • Show author(s) (2002). High prevalence and increasing incidence of Addison's disease in western Norway. Clinical Endocrinology. 787-791.
  • Show author(s) (2002). Endoscopic ultrasonography for preoperative diagnosis and localization of insulinomas. Scandinavian Journal of Gastroenterology. 732-737.
  • Show author(s) (2002). Autoimmune adrenocortical failure in Norway. Autoantibodies and HLA class II associations related to clinical features. Journal of Clinical Endocrinology and Metabolism (JCEM). 618-623.
  • Show author(s) (2002). Autoimmune Regulator and Human Leucocyte Antigen Genotypes as Determinants of the Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Phenotype. Journal of Clinical Endocrinology and Metabolism (JCEM). 2568-2574.
  • Show author(s) (2000). Pteridine-dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism (JCEM). 2944-2950.
  • Show author(s) (2000). Pteridin dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism (JCEM). 2944-2950.
  • Show author(s) (2000). Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. Clinical Endocrinology. 775-780.
  • Show author(s) (2000). Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. Clinical Endocrinology. 775-780.
  • Show author(s) (2000). Inhibition of aromatic L-amino acid decarboxylase activity by human autoantibodies. Clinical and Experimental Immunology. 420-423.
  • Show author(s) (2000). Inhibition of aromatic 1-amino acid decarboxylase by human autoantibodies. Clinical and Experimental Immunology. 420-423.
  • Show author(s) (2000). Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 456-461.
  • Show author(s) (2000). Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 456-461.
  • Show author(s) (2000). Autoantibodies against aromatic L-amino acid decarboxylase delineate a subgroup of patients with Addison's disease. Journal of Clinical Endocrinology and Metabolism (JCEM). 460-463.
  • Show author(s) (2000). Autoantibodies against aromatic L-amino acid decarboxylase delineate a subgroup of patients with Addison's disease. Journal of Clinical Endocrinology and Metabolism (JCEM). 460-463.
  • Show author(s) (1999). Antibodies Against Hair Follicles are Associated with Alopecia Totalis in Autoimmune Polyendocrine Syndrome Type I. Journal of Investigative Dermatology. 1054-1058.
  • Show author(s) (1998). Three sisters with Addison's disease. Journal of Clinical Endocrinology and Metabolism (JCEM). 4204-4206.
  • Show author(s) (1998). Primær binyrebarksvikt - en diagnostisk utfordring. Tidsskrift for Den norske legeforening. 542-544.
  • Show author(s) (1998). Identification of tryptophan hydroxylase as an intestinal autoantigen. The Lancet. 279-283.
  • Show author(s) (1998). Identification of tryptophan hydroxylase as an intestinal autoantigen. The Lancet. 279-283.
  • Show author(s) (1998). A family with hereditary extra-adrenal paragangliomas without evidence for mutations in the Von Hippel Lindau disease or ret genes. Clinical Endocrinology. 11-16.
  • Show author(s) (1998). A cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism is associated with autoimmune Addison's disease in English patients. Clinical Endocrinology. 609-614.
  • Show author(s) (1997). Cytochrome P450IA2 and aromatic L-amino acid decarboxylase are hepatic autoantigens in autoimmune polyendocrine syndrome type I. FEBS Letters. 439-445.
  • Show author(s) (1997). Chromogranin A and chromogranin B in phaeochromocytoma. European Journal of Endocrinology (EJE). 67-73.
  • Show author(s) (1997). Autoantibodies against aromatic L-amino acid decarboxylase in autoimmune polyendocrine syndrome type I correlate with the presence of autoimmune hepatitis and vitiligo. Journal of Clinical Endocrinology and Metabolism (JCEM). 147-150.
Academic lecture
  • Show author(s) (2005). Variable expression of FKBP51 in Addison's Disease - a parameter of glucocorticoid sensitivity ?
  • Show author(s) (2005). Severe neurological impairment in patient with allgrove syndrome caused by frame shift mutation G363X (1066-1067delCT) and novel missense mutation W272S (TGG->TCG).
  • Show author(s) (2005). Ganglioneuroma in patient with adrenal insufficiency - rare coincidence of adrenal cortex and medulla disorders.
  • Show author(s) (2005). Cellular immunity to 21-hydroxylase in patients with autoimmune Addison's disease.
  • Show author(s) (2003). Meet the expert session on "Hypoadrenalism: substitution by corticoids and androgens".
  • Show author(s) (2003). Autoimmune polyendocrine syndromes.
  • Show author(s) (2003). Autoimmune Addisons disease and polyendocrine syndromes.
  • Show author(s) (2002). Prevalens og insidens av Addison's sykdom i Vest-Norge Livskvalitet hos pasienter med Addison's sykdom.
  • Show author(s) (2002). Pituitary tumours in multiple endocrine neoplasia type 1.
  • Show author(s) (2002). Høy forekomst av cøliaci hos pasienter med autoimmun binyrebarksvikt.
  • Show author(s) (2002). Dehydroepiandrosterone replacement in adrenal failure.
  • Show author(s) (2002). Autoimmune polyendocrine syndromes.
  • Show author(s) (2001). Klinisk handläggning av APS I patienter.
  • Show author(s) (2001). Autoimmun primær binyrebarksvikt i Norge. Autoantistoffer og HLA klasse II assosiasjoner relatert til kliniske manifestasjoner.
  • Show author(s) (1997). Ductal autoantigens in Sjøgren's syndrome.
Abstract
  • Show author(s) (2013). Human leukocyte antigen (DQ2/DQ8) and 21-hydroxylase antibodies determine the thyroid peroxidase antibody status of patients in autoimmune Addison's disease. Experimental and clinical endocrinology & diabetes. 2 pages.
  • Show author(s) (2013). Dominant Inheritance in Autoimmune Endocrine Syndrome Type 1. Scandinavian Journal of Immunology. 306-307.
  • Show author(s) (2013). Characterisation of the CYP21A2 Gene in Patients with Autoimmune Addison's Disease. Scandinavian Journal of Immunology. 310-310.
  • Show author(s) (2012). Poly (I:C)-induced CXCL10 production in adrenocortical cells - implications for autoimmune Addison's disease? Immunology. 300-301.
  • Show author(s) (2012). Mice deficient for the autoimmune regulator, Aire, display altered T cell responses against 21-hydroxylase, the major autoantigen in autoimmune Addison's disease. Immunology. 542-542.
  • Show author(s) (2012). Measuring autoantibodies against IL-17F and IL-22 in autoimmune polyedocrine sydnrome type I. Immunology. 673-674.
  • Show author(s) (2012). Deviant expression of defensins in sera and saliva of patients with autoimmune polyendocrine syndrome type I. Immunology. 211-212.
  • Show author(s) (2011). Oral manifestations of autoimmune polyendocrine syndrome type I. Caries Research. 186-187.
  • Show author(s) (2011). Endogenous Production of CXC Chemokine Ligand 10 (CXCL10) by Adrenocortical Cells and its Implications for Autoimmune Addison's Disease. Scandinavian Journal of Immunology. 371-371.
  • Show author(s) (2011). Cytokine Antibodies in Autoimmune Polyendocrine Syndrome Type I Correlates to Chronic candidiasis. Scandinavian Journal of Immunology. 379-379.
  • Show author(s) (2010). The Possible Roles of Interferon-Gamma, CXC Chemokine Ligand 10 (CXCL10) and the CXCR3 Circuit in the Pathogenesis of Autoimmune Addison's Disease. Scandinavian Journal of Immunology. 479-480.
  • Show author(s) (2010). Sexuality, Fertility and Androgens in Women with Addison's Disease. Endocrine reviews. 3.
  • Show author(s) (2010). Nucleoporin 62, a Novel Autoantigen in Patients with Autoimmune Polyendocrine Syndrome Type I (APS I). Scandinavian Journal of Immunology. 493-494.
  • Show author(s) (2010). Immunoreactivity against kidney collecting ducts in patients with autoimmune polyendocrine syndrome type 1 and systemic hypertension. Endocrine journal. S641-S641.
  • Show author(s) (2010). Grapefruit and Liquorice Increase Bioavailable Cortisol in Addison's Disease. Endocrine reviews. 1 pages.
  • Show author(s) (2009). Loss of AIRE Expression in Thymoma Tissue Associated with Multiple Endocrine Autoimmunity: A Novel Case of APS1. Clinical Immunology. S128-S128.
  • Show author(s) (2008). 21-hydroxylase as a T cell autoantigen in autoimmune Addison's disease. Scandinavian Journal of Immunology. 191-191.
  • Show author(s) (2007). Epitope mapping of human aromatic L-amino acid decarboxylase. Scandinavian Journal of Immunology. 592-592.
Academic literature review
  • Show author(s) (2023). Plasma-Metanephrines in Patients with Autoimmune Addison’s Disease with and without Residual Adrenocortical Function. Journal of Clinical Medicine. 1-10.
  • Show author(s) (2022). The genetics of autoimmune Addison disease: past, present and future. Nature Reviews Endocrinology.
  • Show author(s) (2022). Human genetic and immunological determinants of critical COVID-19 pneumonia. Nature. 587-598.
  • Show author(s) (2021). Therapy options for adrenal insufficiency and recommendations for the management of adrenal crisis. Endocrine. 586-594.
  • Show author(s) (2021). B cells and autoantibodies in aire deficiency. Biomedicines. 1-15.
  • Show author(s) (2021). Adrenal insufficiency. The Lancet. 613-629.
  • Show author(s) (2021). Adrenal insufficiency. Nature Reviews Disease Primers. 1-24.
  • Show author(s) (2018). Autoimmune polyendocrine syndromes. New England Journal of Medicine. 1132-1141.
  • Show author(s) (2016). Management of endocrine disease - Epidemiology, quality of life and complications of primary adrenal insufficiency: A review. European Journal of Endocrinology (EJE). R107-R116.
  • Show author(s) (2016). Autoimmune regulator and self-tolerance - molecular and clinical aspects. Immunological Reviews. 127-140.
  • Show author(s) (2016). AIRE-mutations and autoimmune disease. Current Opinion in Immunology. 8-15.
  • Show author(s) (2010). Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis. Immunity. 479-487.
  • Show author(s) (2009). Immunology of Addison's Disease and premature ovarian failure. Endocrinology and metabolism clinics of North America (Print). 389-405.
  • Show author(s) (2009). Autoantibodies in autoimmune polyglandular syndrome type I patients react with major brain neurotransmitter systems. Journal of Comparative Neurology. 1-20.
  • Show author(s) (2008). Replacement therapy for Addison's disease: recent developments. Expert Opinion on Investigational Drugs. 497-509.

More information in national current research information system (CRIStin)

Co-ordinator of the EU FP7 project Euradrenal

Consultant in endocrinology and internal medicine