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Gottfried Greve's picture

Gottfried Greve

Professor
  • E-mailGottfried.Greve@uib.no
  • Phone+47 55 97 52 75+47 995 81 464
  • Visitor Address
    Barneklinikken/ Hjerteavdelingen, Haukeland universitetssykehus
    Bergen
  • Postal Address
    Postboks 7800
    5020 Bergen

Heart and vascular physiology in children and adolescents

 

 

 

Paediatrics; esp. congential heart defects

 

  • Medical students
  • Continuous Medical Education

 

Vice-dean for education 2010-11

Chairing the Program Committee for Continuous Medical Education 2011-date

Scientific international coordinator 

 

Academic article
  • Show author(s) 2021. Vascular endothelial function assessed by flow-mediated vasodilatation in young adults born very preterm or with extremely low birthweight: A regional cohort study. Frontiers in pediatrics. 1-13.
  • Show author(s) 2021. Speckle tracking derived strain in neonates: planes, layers and drift. The International Journal of Cardiovascular Imaging. 1-13.
  • Show author(s) 2021. Schistosomiasis hos norske studenter etter opphold i Afrika. Tidsskrift for Den norske legeforening. 243-247.
  • Show author(s) 2021. Interdisciplinary Approaches Suggested for Children With Multiple Hospital Referrals Presenting With Non-specific Conditions. Frontiers in pediatrics. 1-7.
  • Show author(s) 2021. Effect of temporal and spatial smoothing on speckle–tracking-derived strain in neonates. Pediatric Cardiology. 743-752.
  • Show author(s) 2020. How can we improve specialist health services for children with multi-referrals? Parent reported experience. BMC Health Services Research. 1-11.
  • Show author(s) 2020. Complex care pathways for children with multiple referrals demonstrated in a retrospective population-based study. Acta Paediatrica. 1-7.
  • Show author(s) 2019. Cardiopulmonary capacity in children during exercise testing: The differences between treadmill and upright and supine cycle ergometry. Frontiers in Physiology. 1-10.
  • Show author(s) 2018. The five-year survival of children with Down syndrome in Norway 1994-2009 differed by associated congenital heart defects and extracardiac malformations. Acta Paediatrica. 845-853.
  • Show author(s) 2018. Effectiveness of an oral health intervention program for children with congenital Health defects. BMC Oral Health. 1-13.
  • Show author(s) 2017. Recurrence of congenital heart defects among siblings - a nationwide study. American Journal of Medical Genetics. Part A. 1575-1585.
  • Show author(s) 2017. Mid-childhood outcomes after pre-viable preterm premature rupture of membranes. Journal of Perinatology. 1053-1059.
  • Show author(s) 2016. Oral health among children with congenital heart defects in Western Norway. European Archives of Paediatric Dentistry. 397-406.
  • Show author(s) 2016. Optimal acquisition settings for speckle tracking echocardiography-derived strains in infants: An in vitro study. Ultrasound in Medicine and Biology. 1660-1670.
  • Show author(s) 2016. Mortality and complications in 3495 children with isolated ventricular septal defects. Archives of Disease in Childhood. 808-813.
  • Show author(s) 2016. 4D Left Ventricular Resultant Wall Motion and Blood Flow assessed by Phase-Shift Velocity Mapping at high-field 3T MRI. Clinical Physiology and Functional Imaging. 615-621.
  • Show author(s) 2015. Possible Common Aetiology behind Maternal Preeclampsia and Congenital Heart Defects in the Child: a Cardiovascular Diseases in Norway Project Study. Paediatric and Perinatal Epidemiology. 76-85.
  • Show author(s) 2015. Periconceptional folic acid supplementation and infant risk of congenital heart defects in Norway 1999-2009. Paediatric and Perinatal Epidemiology. 391-400.
  • Show author(s) 2015. Parental anxiety related to referral of childhood heart murmur; an observational/interventional study. BMC Pediatrics.
  • Show author(s) 2014. Birth prevalence of congenital heart defects in Norway 1994-2009 - A nationwide study. American Heart Journal. 956-964.
  • Show author(s) 2013. Endocarditis prophylaxis and congenital heart defects in the Norwegian Public Dental Service. Acta Paediatrica. Supplement. 29-34.
  • Show author(s) 2013. Assessment of vascular reactivity in the peripheral and coronary arteries by cine 3T-magnetic resonance imaging in young normotensive adults after surgery for coarctation of the aorta. Pediatric Cardiology. 661-669.
  • Show author(s) 2012. Repeatability of blood pressure measurements during treadmill exercise. Blood Pressure Monitoring. 69-72.
  • Show author(s) 2012. Left ventricular function in children and adults after renal transplantation in childhood. Pediatric nephrology (Berlin, West). 1565-1574.
  • Show author(s) 2012. Assessment of coronary flow reserve in the coronary sinus by cine 3T-magnetic resonance imaging in young adults after surgery for tetralogy of fallot. Pediatric Cardiology. 65-74.
  • Show author(s) 2012. Anbefalinger for bruk av endokardittprofylakse knyttet til tannbehandling. Den norske tannlegeforenings tidende. 574-578.
  • Show author(s) 2011. Kinetic of monocytes Fc gamma receptors in patients after coronary artery bypass. Central European Journal of Medicine. 31-36.
  • Show author(s) 2011. Accurate single-nucleotide polymorphism allele assignment in trisomic or duplicated regions by using a single base-extension assay with MALDI-TOF mass spectrometry. Clinical Chemistry. 1188-1195.
  • Show author(s) 2009. Føtale arytmier. Hjerteforum. 57-68.
  • Show author(s) 2008. Molecular genetic analysis of long QT syndrome in Norway indicating a high prevalence of heterozygous mutation carriers. Scandinavian Journal of Clinical and Laboratory Investigation. 362-U28.
  • Show author(s) 2008. Brain abscess caused by paradoxical embolization in Ebstein's anomaly. European Heart Journal-Cardiovascular Imaging. 105-106.
  • Show author(s) 2007. Successful treatment of severe heart failure in an infant with Hurler syndrome. The Journal of Inherited Metabolic Disease (JIMD). 820-820.
  • Show author(s) 2006. Risikofaktor for brå hjertedød ved lang QT-syndrom. Tidsskrift for Den norske legeforening. 2515-2519.
  • Show author(s) 2006. Atriventrikulær nodal takykardi hos barn. Tidsskrift for Den norske legeforening. 2373-2376.
  • Show author(s) 2005. Trenger pasienter med ventrikkelseptumdefekt endokardittprofylakse? Tidsskrift for Den norske legeforening. 3256-3258.
  • Show author(s) 2004. Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambs. American Journal of Physiology. Heart and Circulatory Physiology. H1008-H1014.
  • Show author(s) 2004. Rate dependence of mechanically induced electrophysiological changes in right ventricle of anaesthetized lambs during pulmonary artery occlusion. Acta Physiologica Scandinavica. 13-19.
  • Show author(s) 2004. Pulmonal hypertensjon hos barn (del 2). Hjerteforum. 36-45.
  • Show author(s) 2004. Pulmonal hypertensjon hos barn (del 1). Hjerteforum. 35-44.
  • Show author(s) 2004. Miniserie om pulmonal hypertensjon hos barn (Del 2 av 2). (Behandling). Hjerteforum. 36-45.
  • Show author(s) 2004. Miniserie om pulmonal hypertensjon hos barn (Del 1 av 2). Åsaker, basal patofysiologi og utredning. Hjerteforum. 35-44.
  • Show author(s) 2004. Exercise capacity in young adults with hypertension and systolic blood pressure difference between right arm and leg after repair of coarctation of the aorta. European Journal of Applied Physiology. 116-123.
  • Show author(s) 2003. Transcatheter closure of patent foramen ovale in young stroke patients. Tidsskrift for Den norske legeforening. 785-788.
  • Show author(s) 2003. Right ventricular myocardial responses to pulmonary reguritation in lambs: disturbances and conduktion. Pediatric Research. 529-535.
  • Show author(s) 2003. Magnetic resonance imaging of patients with increased blood pressure and altered blood pressure response to exercise after coarctation repair. J Scand Cardiovasc. 98-103.
  • Show author(s) 2001. Right ventricular distesiom alters monophasic action potential duration pulmonary arterial occulsion in anaestethised lambs: evidence for arrythmogenic right ventricular mechanoelectrical feedback. Experimental Physiology. 651-657.
  • Show author(s) 2000. Heterotrisomy, a significant contributing factor to ventricular septal defect associated with Down syndrome? Human Genetics. 476-482.
  • Show author(s) 1992. Atrial natriuretic factor in cats subjected to acute myocardial ischaemia. Scandinavian Journal of Clinical and Laboratory Investigation. 571-578.
  • Show author(s) 1991. Ultrastructural changes at the border of the ischaemic zone within one hour of coronary artery occlusion. Acta Physiologica Scandinavica Supplementum. 109-116.
  • Show author(s) 1990. Early morphologic changes in cat heart muscle cells after acute coronary artery occlusion. American Journal of Pathology. 273-283.
  • Show author(s) 1988. Effects of verapamil and timolol on cellular morphometric changes in cat hearts with regional ischaemia. Virchows Archiv. A, Pathological anatomy and histopathology. 291-299.
  • Show author(s) 1988. Cellular morphometric changes in cat hearts subjected to three hours of regional ischaemia. Virchows Archiv. A, Pathological anatomy and histopathology. 205-213.
Popular scientific article
  • Show author(s) 2005. Måling av blodstrømshastigheter i koronararterier hos barn ved transtorakal ekko-Dopplerkardiografi - en praktisk tilnærming. Hjerteforum. 50-54.
  • Show author(s) 2005. Måling av blodstrømshastigheter i koronararterier hos barn ved transtorakal ekko-Dopplerkardiografi - en praktisk tilnærming. Ductus. 3-8.
  • Show author(s) 2005. Koronarsirkulasjon hos barn. Hjerteforum. 45-48.
  • Show author(s) 2005. Koronarsirkulasjon barn. Ductus.
Letter to the editor
  • Show author(s) 2016. Preeclampsia and congenital heart defects. Journal of the American Medical Association (JAMA). 1167-1168.
Doctoral dissertation
  • Show author(s) 1990. Across the border : an ultrastructural study of hearts with regional ischaemia.
Abstract
  • Show author(s) 2016. Visualization and Quantification of Regional Ventricular Wall and Blood Velocities by 3T 4D PC-MRI. Journal of cardiovascular magnetic resonance. 349.
  • Show author(s) 2015. Optimizing speckle tracking echocardiography strain measurements in infants: an in-vitro phantom study . European Heart Journal-Cardiovascular Imaging. 102-129.
  • Show author(s) 2013. Day To Day Repeatability And Circadian Variation Of Lung Volume Measurements. Medicine & Science in Sports & Exercise. 291-291.
  • Show author(s) 2010. Novel high resolution method for visualization of regional ventricular wall motion and blood flow by 3T MRI. Journal of cardiovascular magnetic resonance. 234.
  • Show author(s) 2010. Blood velocities measured in the coronary sinus by 3T- MRI in patients operated for coarctation of the aorta. Journal of cardiovascular magnetic resonance. 31.
  • Show author(s) 2004. Right ventricular function of patients with transposition of the great arteries. Journal of cardiovascular magnetic resonance. 290-292.
  • Show author(s) 1990. Atrial Natriuretic peptide in acute myocardial infarction: An ultrastructural and biochemical study. Journal of Molecular and Cellular Cardiology. S63.
  • Show author(s) 1986. Morphometric changes in the ischaemic and border zones in cat hearts sugjected to 3 hours of regional ischaemia. Journal of Molecular and Cellular Cardiology.
  • Show author(s) 1986. Effects of timolol and verapamil on morphological changes in cat hearts with LAD occlusion. Journal of Molecular and Cellular Cardiology.
Poster
  • Show author(s) 2018. Schistosomiasis in Norwegian medical students .
  • Show author(s) 2017. Visualization and Quantification of Right Ventricular Wall Velocities and Blood Flow by 3T 4D PC-MRI.
  • Show author(s) 2013. Caries pattern in 5-yr-old children with congenital heart defects (CHD) in western Norway. (Abstract 155).
  • Show author(s) 2011. Antibiotoc Phrophylaxis in dental treatment of children with congential health defects (CHD).
  • Show author(s) 2009. Blood velocities measured in the coronary sinus by 3T-MRI in patients operated for coarctation of the aorta.
  • Show author(s) 2008. Blood velocities measured in the coronary sinus by 3T-MRI in patients operated for tetralogy of Fallot.
  • Show author(s) 2007. The significance of the bloodstream profile in a pathological dilated aorta.
  • Show author(s) 2006. 3-D vector visualisation of ventricular wall motion across a volume by the use of 3T MRI.
  • Show author(s) 2005. 3D vector and streamline visualisation of time-dependent blood flow across a volume of the aortic lumen - an open-source approach based on Java.
Academic literature review
  • Show author(s) 2019. What is left ventricular strain in healthy neonates? A systematic review and meta-analysis. Pediatric Cardiology. 1-11.
  • Show author(s) 2016. Maternal Diabetes, Birth Weight, and Neonatal Risk of Congenital Heart Defects in Norway, 1994-2009. Obstetrics and Gynecology. 1116-1125.
  • Show author(s) 2014. Fontansirkulasjon - en klinisk utfordring. Hjerteforum. 43-57.
  • Show author(s) 2013. Trends in pediatric imaging: ultrasound. Acta Radiologica. 1096-1105.
  • Show author(s) 2010. Forslag til retningslinjer for kardiologisk utredning og oppfølgning av pasienter med Turners syndrom. Hjerteforum. 45-49.
  • Show author(s) 2010. Eisenmenger syndrom - Fortsatt en utfordring. Hjerteforum. 27-35.
  • Show author(s) 2009. Genetic counseling in congenital long QT syndrome. Tidsskrift for Den norske legeforening. 1226-1229.
  • Show author(s) 2008. Intrauterin veksthemming og vaskulære forandringer hos nyfødte. Tidsskrift for Den norske legeforening. 177-179.

More information in national current research information system (CRIStin)

1: Cuypers J, Leirgul E, Larsen TH, Berg A, Omdal TR, Greve G. Assessment of

Vascular Reactivity in the Peripheral and Coronary Arteries by Cine 3T-Magnetic

Resonance Imaging in Young Normotensive Adults after Surgery for Coarctation of

the Aorta. Pediatr Cardiol. 2012 Oct 13. [Epub ahead of print]

 

2: Sivertsen TB, Astrøm AN, Greve G, Assmus J, Skeie MS. Endocarditis prophylaxis 

and congenital heart defects in the Norwegian Public Dental Service. Acta

Paediatr. 2013 Jan;102(1):29-34.

 

3: Hirth A, Edwards NC, Greve G, Tangeraas T, Gerdts E, Lenes K, Norgård G. Left 

ventricular function in children and adults after renal transplantation in

childhood. Pediatr Nephrol. 2012 Sep;27(9):1565-74.

 

4: Insteb√∏ A, Helgheim V, Greve G. Repeatability of blood pressure measurements

during treadmill exercise. Blood Press Monit. 2012 Apr;17(2):69-72. 

 

5: Cuypers J, Leirgul E, Samnøy S, Larsen TH, Berg A, Schulze-Neick I, Greve G.

Assessment of coronary flow reserve in the coronary sinus by cine 3T-magnetic

resonance imaging in young adults after surgery for tetralogy of Fallot. Pediatr 

Cardiol. 2012 Jan;33(1):65-74. 

 

6: Trewick AL, Moustafa JS, de Smith AJ, Froguel P, Greve G, Njølstad PR, Coin

LJ, Blakemore AI. Accurate single-nucleotide polymorphism allele assignment in

trisomic or duplicated regions by using a single base-extension assay with

MALDI-TOF mass spectrometry. Clin Chem. 2011 Aug;57(8):1188-95. 

 

 

7: Hamang A, Solberg B, Bjorvatn C, Greve G, Øyen N. [Genetic counseling in

congenital long QT syndrome]. Tidsskr Nor Laegeforen. 2009 Jun 11;129(12):1226-9.

doi: 10.4045/tidsskr.09.32621. Review. Norwegian. PubMed PMID: 19521446.

 

 

8: Berge KE, Haugaa KH, Früh A, Anfinsen OG, Gjesdal K, Siem G, Oyen N, Greve G, 

Carlsson A, Rognum TO, Hallerud M, Kongsård E, Amlie JP, Leren TP. Molecular

genetic analysis of long QT syndrome in Norway indicating a high prevalence of

heterozygous mutation carriers. Scand J Clin Lab Invest. 2008;68(5):362-8. 

 

 

9: Svangtun H, Greve G, Leirgul E, Berg A. [Intrauterine growth retardation and

vascular changes in neonates]. Tidsskr Nor Laegeforen. 2008 Jan 17;128(2):177-9. 

 

10: Hirth A, Berg A, Greve G. Successful treatment of severe heart failure in an 

infant with Hurler syndrome. J Inherit Metab Dis. 2007 Oct;30(5):820. 

 

11: Lønnebakken MT, Greve G, Leirgul E, Gerdts E. Brain abscess caused by

paradoxical embolization in Ebstein's anomaly. Eur J Echocardiogr. 2008

Jan;9(1):105-6

 

12: Greve G, Leirgul E. [Tachyarrhythmia and cor triatriatum]. Tidsskr Nor

Laegeforen. 2007 Apr 19;127(8):1058.

 

13: Thorsen PJ, Berg A, Hoff PI, Greve G. [Risk factors for sudden cardiac death 

related to the long QT syndrome]. Tidsskr Nor Laegeforen. 2006 Oct

5;126(19):2515-9

 

 

14: Vislie CH, Mikkelsen RB, Hoff PI, Greve G. [Atrioventricular nodal reentry

tachycardia in children]. Tidsskr Nor Laegeforen. 2006 Sep 21;126(18):2373-6

 

15: Midtbø H, Hirth A, Norgård G, Greve G. [Do patients with ventricular septal

defect need endocarditis prophylaxis?]. Tidsskr Nor Laegeforen. 2005 Dec

1;125(23):3256-8. 

 

16: Berg A, Greve G, Hirth A, Rosland GA, Norgård G. [Evaluation of cardiac

murmurs in children]. Tidsskr Nor Laegeforen. 2005 Apr 21;125(8):1000-3.

 

17: Norgård G, Greve G, Rosland GA, Berg A. [Referral practice and clinical

assessment of heart murmurs in children]. Tidsskr Nor Laegeforen. 2005 Apr

21;125(8):996-8. 

 

18: Zadinello M, Greve G, Liu XQ, Barbosa JR Jr, Schulze-Neick I, Wilkinson JL,

Redington AN. Angiotensin I converting enzyme genotype affects ventricular

remodelling in children with aortic coarctation. Heart. 2005 Mar;91(3):367-8.

 

19: Instebø A, Norgård G, Helgheim V, Røksund OD, Segadal L, Greve G. Exercise

capacity in young adults with hypertension and systolic blood pressure difference

between right arm and leg after repair of coarctation of the aorta. Eur J Appl

Physiol. 2004 Oct;93(1-2):116-23. 

 

20: Chen RL, Penny DJ, Greve G, Lab MJ. Stretch-induced regional mechanoelectric 

dispersion and arrhythmia in the right ventricle of anesthetized lambs. Am J

Physiol Heart Circ Physiol. 2004 Mar;286(3):H1008-14

 

21: Chen R, Penny DJ, Greve G, Lab MJ. Rate dependence of mechanically induced

electrophysiological changes in right ventricle of anaesthetized lambs during

pulmonary artery occlusion. Acta Physiol Scand. 2004 Jan;180(1):13-9. 

 

22: Gray R, Greve G, Chen R, Fry C, Barron D, Lab MJ, White PA, Redington AN,

Penny DJ. Right ventricular myocardial responses to chronic pulmonary

regurgitation in lambs: disturbances of activation and conduction. Pediatr Res.

2003 Oct;54(4):529-35. 

 

23: Larsen TH, Taxt AM, Aslaksen A, Segadal L, Norgård G, Røksund OD, Greve G.

Magnetic resonance imaging of patients with increased blood pressure and altered 

blood pressure response to exercise after coarctation repair. Scand Cardiovasc J.

2003 May;37(2):98-103

 

24: Hirth A, Greve G, Rosland GA, Thomassen L, Norgård G. [Transcatheter closure 

of patent foramen ovale in young stroke patients]. Tidsskr Nor Laegeforen. 2003

Mar 20;123(6):785-8

 

25: Berg A, Norgård G, Greve G. Haemoptysis as a late complication of a Mustard

operation treated by balloon dilation of a superior caval venous obstruction.

Cardiol Young. 2002 May;12(3):298-301

 

·      Reproducibility of physiologic tests for measuring basic metabolism, and heart- and lung function

·      Measurements of blood flow in the aorta, and coronary and brachial arteries in patients with congenital heart defects by cMRI and echocardiography 

·      Left ventricular systolic deformation in subclinical metabolic cardiomyopathies

 

·      Congenital heart defects in Norway - a nation-wide study