- E-mailInari.Kursula@uib.no
- Phone+47 55 58 68 46
- Visitor AddressJonas Lies vei 915009 BergenRoom5B132B
- Postal AddressPostboks 78045020 Bergen
I am a structural biologist, interested in cell motility and in particular how malaria parasites move and invade their host cells. I did my PhD in structural biology at the University of Oulu, Finland, in 2003. After post-doctoral stays at the EMBL Hamburg Outstation and the Karolinska Institute, I have led my own research group in Oulu since 2008. In parallel, I have been a junior group leader at the Helmholtz Centre for Infection Research at CSSB/DESY in Hamburg (2009-2015), Academy of Finland Research Fellow (2012-2017), a 20% professor at the University of Bergen (2014-2017), and a visiting scientist at the European XFEL (2015-). Since 2017, my main position is at the Department of Biomedicine, University of Bergen.
Research in my group is focused on understanding malaria parasite gliding motility at the molecular/atomic level. For this aim, we use a broad range of structural biology and biochemical/biophysical methods.
No. of publications: 56 - No. of citations: 1747 - h-index: 25
Methods in Biomedical Research - BMED320
2023
Hung YF, Chen Q, Pires I, Han H, Rosenthal PB & Kursula I (2023) Structure of Toxoplasma gondii glideosome-associated connector suggests a role as an elastic element in actomyosin force generation for gliding motility. Preprint available on bioRxiv: https://doi.org/10.1101/2022.12.09.519741.
Dans MG, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, Das S, Schneider MP, Jonsdottir TK, Gabriela M, Gancheva MR, Tonkin C, Mollard V, Goodman CD, McFadden GI, Wilson DW, Barry AE, Crabb BS, de-Koning-Ward TF, Sleebs BE, Kursula I & Gilson PR (2023) The sulfonylpiperazine MMV020291 prevents red blood cell invasion by the malaria parasite Plasmodium falciparum through interference with actin-1/profilin dynamics. Preprint available on bioRxiv: https://doi.org/10.1101/2022.09.29.510018.
Lopez AJ, Andreadaki M, Vahokoski J, Deligianni E, Calder LJ, Camerini S, Freitag A, Bergmann U, Rosenthal PB, Sidén-Kiamos I & Kursula I (2023) Structure and function of Plasmodium actin II in the parasite mosquito stages. PLoS Pathog 19: e1011174.
2022
Pires I, Hung YF, Bergmann U, Molloy JE & Kursula I (2022) Analysis of Plasmodium falciparum myosin B ATPase activity and structure in complex with the calmodulin-like domain of its light chain MLC-B. J Biol Chem in press, https://doi.org/10.1016/j.jbc.2022.102634
Vahokoski J, Calder L, Lopez AJ, Molloy JE, Kursula I & Rosenthal PB (2022) High-resolution structures of malaria parasite actomyosin and actin filaments. PLoS Pathog 18: e1010408.
- Bendes ÁÁ, Kursula P & Kursula I (2022) Structure and function of an atypical homodimeric actin capping protein from the malaria parasite. Cell Mol Life Sci 79: 125.
2021
Han H, Round E, Schubert R, Gül Y, Makroczyová J, Meza D, Heuser P, Aepfelbacher M, Barák I, Betzel C, Fromme P, Kursula I, Nissen P, Tereschenko E, Schulz J, Uetrecht C, Ulicný J, Wilmanns M, Hajdu J, Lamzin VS & Lorenzen K. (2021) The XBI BioLab for life science experiments at the European XFEL. J Appl Crystallogr 54: 7-21.
Bustad HJ, Kallio JP, Laitaoja M, Toska K, Kursula I, Martinez A & Jänis J (2021) Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism. iScience 24: 102152.
2020
Makumire S, Zininga T, Vahokoski J, Kursula I & Shonhai A (2020) Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers. PLoS ONE 15: 0226657.
Bendes ÁÁ, Chatterjee M, Götte B, Kursula P & Kursula I (2020) Functional homo- and heterodimeric actin capping proteins from the malaria parasite. Biochem Biophys Res Commun 525: 681-686.
Moreau CA, Quadt KA, Piirainen H, Kumar H, Bhargav SP, Strauss L, Tolja NH, Wade RC, Spatz JP, Kursula I & Frischknecht F (2020) Optical tweezers uncover a function of profilin in force generation during malaria parasite motility independent of actin binding. J Cell Sci 134: jcs233775.
2019
Kumpula EP, Lopez AJ, Tajedin L, Han H & Kursula I (2019) Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation. PLoS Biol 17: e3000315.
Saghaug CS, Klotz C, Kallio JP, Brattbakk HR, Stokowy T, Aebischer T, Kursula I, Langeland N & Hanevik K (2019) Genetic variation in metronidazole metabolism and oxidative stress pathways in clinical Giardia lamblia assemblage A and B isolates. Infect Drug Resist 12: 1221-1235.
Szigetvari PD, Muruganandam G, Kallio JP, Hallin EI, Fossbakk A, Loris R, Kursula I, Møller LB, Knappskog PM, Kursula P & Haavik J (2019) The quaternary structure of human tyrosine hydroxylase: effects of dystonia-associated missense variants on oligomeric state and enzyme activity. J Neurochem 148: 291-306.
2018
Mukherjee B, Tessaro F, Vahokoski J, Kursula I, Marq JB, Scapozza L & Soldati-Favre D (2018) Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases. EMBO J 37: e98047.
2017
Pino P, Caldelari R, Mukherjee B, Vahokoski J, Klages N, Maco B, Collins CR, Blackman MJ, Kursula I, Heussler V, Brochet M & Soldati-Favre D (2017) A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress. Science 358: 522-528.
Kumpula EP, Pires IP, Lasiwa D, Piirainen H, Bergmann U, Vahokoski J & Kursula I (2017) Apicomplexan actin polymerization depends on nucleation. Sci Rep 7: 12137.
Pospich S, Kumpula EP, von der Ecken J, Vahokoski J, Kursula I & Raunser S (2017) Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proc Natl Acad Sci 114: 10636-10641.
Green JL, Wall RJ, Vahokoski J, Yusuf NA, Ridzuan MAM, Stanway RR, Stock J, Knuepfer E, Brady D, Martin SR, Howell SA, Pires IP, Moon RW, Molloy JE, Kursula I, Tewari R & Holder AA (2017) Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility. J Biol Chem 292: 17857-17875.
Panneerselvam S, Kumpula EP, Kursula I, Burkhardt A & Meents A (2017) Rapid cadmium SAD phasing at the standard wavelength (1 Å). Acta Cryst D 73: 581-590.
Moreau C, Bhargav SP, Kumar H, Quadt KA, Piirainen H, Strauss L, Kehrer J, Streichfuss M, Spatz J, Wade R, Kursula I & Frischknecht F (2017) A unique profilin-actin interface is important for malaria parasite motility. PLoS Pathog 13: e1006412.
Muruganandam G, Raasakka A, Myllykoski M, Kursula I & Kursula P (2017) Structural similarities and functional differences point to evolutionary relationship between tRNA healing enzymes and the myelin enzyme CNPase. BMC Biochem 18: 7.
2016
Jacot D, Tosetti N, Pires I, Stock J, Graindorge A, Hung YF, Han H, Tewari R, Kursula I & Soldati-Favre D (2016) An apicomplexan actin-binding protein serves as a connector and lipid sensor to coordinate motility and invasion. Cell Host Microbe 20: 731-743.
Mueller C, Samoo A, Hammoudi PM, Klages N, Kallio JP, Kursula I & Soldati-Favre D (2016) Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein. J Cell Sci 129: 1031-1045.
2015
- Raasakka A, Myllykoski M, Laulumaa S, Lehtimäki M, Haertlein M, Moulin M, Kursula I & Kursula P (2015) Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3-cyclic nucleotide 3'-phosphodiesterase. Sci Rep 5: 16520.
- Bhargav SP, Vahokoski J, Kallio JP, Torda AE, Kursula P & Kursula I (2015) Two independently folding units of Plasmodium profilin suggest evolution via gene fusion. Cell Mol Life Sci 72: 4193-4203.
- Kumpula EP & Kursula I (2015) Towards a molecular understanding of the apicomplexan actin motor – on a road to novel targets for malaria remedies? Acta Cryst F 71: 500-513.
2014
- Salamun J, Kallio JP, Daher W, Soldati-Favre D & Kursula I (2014) Structure of Toxoplasma gondii coronin – an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress. FASEB J 28: 4729-4747.
- Vahokoski J, Bhargav SP, Desfosses A, Andreadaki M, Kumpula EP, Muñico Martinez S, Ignatev A, Lepper S, Frischknecht F, Sidén-Kiamos I, Sachse C & Kursula I (2014) Structural differences explain diverse functions of Plasmodium actins. PLoS Pathog 10: e1004091.
- Kallio JP & Kursula I (2014) Recombinant production, purification, and crystallization of the Toxoplasma gondii coronin WD40 domain. Acta Cryst F 70: 517-521.
- Ruskamo S, Yadav RP, Sharma S, Lehtimäki M, Laulumaa S, Aggarwal S, Simons M, Bürck J, Ulrich AS, Juffer AH, Kursula I & Kursula P (2014) Atomic-resolution view into structure-function relationships of human myelin peripheral membrane protein P2. Acta Cryst D 70: 165-176.
2013
- Muruganandam G, Bürck J, Ulrich AS, Kursula I & Kursula P (2013) Lipid membrane association of myelin proteins and peptide segments studied by oriented and synchrotron radiation circular dichroism spectroscopy. J Phys Chem B 117: 14983-14993.
- Vervaet N, Kallio JP, Meier S, Salmivaara E, Eberhardt M, Zhang S, Sun X, Wu Z, Kursula P & Kursula I (2013) Recombinant production, crystallization, and preliminary structural characterization of Schistosoma japonicum profilin. Acta Cryst F 69: 1264-1267.
Bhargav SP, Vahokoski J, Kumpula EP & Kursula I (2013) Crystallization and preliminary structural characterization of the two actin isoforms of the malaria parasite. Acta Cryst F 69: 1171-1176.
- Wedderhoff I, Kursula I, Groves MR & Ortiz de Orué Lucana D (2013) Iron binding at specific sites within the octameric HbpS protects streptomycetes from iron-mediated oxidative stress. PLoS ONE 8: e71579.
- Myllykoski M, Raasakka A, Lehtimäki M, Han H, Kursula I & Kursula P (2013) Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a member of the 2H phosphoesterase family. J Mol Biol 425: 4307-4322.
2012
- Ruskamo S, Chukhlieb M, Vahokoski J, Bhargav SP, Liang F, Kursula I & Kursula P (2012) Juxtanodin is an intrinsically disordered F-actin binding protein. Sci Rep 2: 899.
- Myllykoski M, Itoh K, Kangas SM, Heape AM, Kang SU, Lubec G, Kursula I & Kursula P (2012) Direct molecular interaction of the myelin enzyme 2’,3’-cyclic nucleotide 3’-phosphodiesterase with the calcium sensor calmodulin. J Neurochem 123: 515-524.
- Ignatev A, Bhargav SP, Vahokoski J, Kursula P & Kursula I (2012) The lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domain. PLoS ONE 7: e33586.
2011
- Singh BK, Sattler JM, Chatterjee M, Huttu J, Schüler H & Kursula I (2011) Crystal structures explain functional differences in the two actin depolymerization factors of the malaria parasite. J Biol Chem 286: 28256-28264.
- Nilsson S, Moll K, Angeletti D, Albrecht L, Kursula I, Jiang N, Sun X, Berzins K, Wahlgren M & Chen Q (2011) Characterization of the Duffy-binding like domain of Plasmodium falciparum blood-stage antigen 332. Malaria Res Treat 2011: 671439.
- Patel AK, Yadav RP, Majava V, Kursula I & Kursula P (2011) Structure of the pro-apoptotic protein kinase DAPK2, a member of the death-associated protein kinase family J Mol Biol 409: 369-383.
2010
- Huttu J, Singh BK, Bhargav SP, Sattler JM, Schüler H & Kursula I (2010) Crystallization and preliminary structural characterization of the two actin depolymerization factors of the malaria parasite. Acta Cryst F 66: 583-587.
- Majava V, Polverini E, Mazzini A, Nanekar R, Knoll W, Peters J, Natali F, Baumgärtel P, Kursula I & Kursula P (2010) Structural and functional characterization of human peripheral nervous system myelin protein P2. PLoS ONE 5: e10300.
- Wigren E, Bourhis JM, Kursula I, Guy JE & Lindqvist Y (2010) Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of Factor V and Factor VIII. FEBS Lett 584: 878-882.
2008
- Kursula I, Kursula P, Ganter M, Panjikar S, Matuschewski K & Schüler H (2008) Structural basis for parasite‐specific functions of the divergent profilin of Plasmodium falciparum. Structure 16: 1638-1648.
- Kursula P, Kursula I, Massimi M, Song YH, Downer, J, Stanley WA, Witke W & Wilmanns M (2008) High‐resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: formin homology 1 domain of mDia1 and the proline rich domain of VASP. J Mol Biol 375: 270‐290.
2007
Sultana A, Alexeev I, Kursula I, Mäntsälä P, Niemi J & Schneider G (2007) Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidase: indications of multidomain pseudomerohedral twinning. Acta Cryst D 63: 149‐159.
2006
Müller S, Kursula I, Zou P & Wilmanns M (2006) Crystal structure of the PB1 domain of NBR1. FEBS Lett 581: 341‐344.
2005
Kursula I, Heape AM & Kursula P (2005) Crystal structure of non‐fused glutathione‐S-transferase from Schistosoma japonicum in complex with glutathione. Protein Pept Lett 12: 709‐712.
2004
Kursula I, Salin M, Sun J, Norledge BV, Haapalainen AM, Sampson NS & Wierenga RK (2004) Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase. Protein Eng Des Sel 17: 375‐382.
2003
Kursula I & Wierenga RK (2003) Crystal structure of triosephosphate isomerase complexed with 2‐phosphoglycolate at 0.83‐Å resolution. J Biol Chem 278: 9544‐9551.
2002
Kursula I, Partanen S, Lambeir AM & Wierenga RK (2002) The importance of the conserved Arg191‐Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis. FEBS Lett 518: 39‐42.
2001
Kursula I, Partanen S, Lambeir AM, Antonov DM, Augustyns K & Wierenga RK (2001) Structural determinants for ligand binding and catalysis of triosephosphate isomerase. Eur J Biochem 268: 5189‐5196.
2000
- Lambeir AM, Backmann J, Ruiz‐Sanz J, Filimonov V, Nielsen JE, Kursula I, Norledge BV & Wierenga RK (2000) The ionisation of Glu65 buried at the monomer‐monomer interface in Leishmana mexicana triosephosphate isomerase is thermodynamically linked to the stability of the dimer. Eur J Biochem 267: 2516‐2524.
1999
Pospiech H, Kursula I, Abdel‐Aziz W, Malkas L, Uitto L, Kastelli M, Vihinen‐Ranta M, Eskelinen S & Syväoja JE (1999) A neutralizing antibody against human DNA polymerase ε inhibits cellular but not SV40 DNA replication. Nucleic Acids Res 27: 3799‐3804.
- (2022). Structure and function of an atypical homodimeric actin capping protein from the malaria parasite. Cellular and Molecular Life Sciences (CMLS). 15 pages.
- (2022). High-resolution structures of malaria parasite actomyosin and actin filaments. PLoS Pathogens. 20 pages.
- (2022). Analysis of Plasmodium falciparum myosin B ATPase activity and structure in complex with the calmodulin-like domain of its light chain MLC-B. Journal of Biological Chemistry. 12 pages.
- (2021). Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism. iScience.
- (2020). Functional homo- and heterodimeric actin capping proteins from the malaria parasite. Biochemical and Biophysical Research Communications - BBRC. 681-686.
- (2020). Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers. PLOS ONE.
- (2020). A function of profilin in force generation during malaria parasite motility that is independent of actin binding. Journal of Cell Science. 1-12.
- (2019). Genetic variation in metronidazole metabolism and oxidative stress pathways in clinical giardia lamblia assemblage A and B isolates. Infection and Drug Resistance. 1221-1235.
- (2019). Atomic view into plasmodium actin polymerization, ATP hydrolysis, and fragmentation. PLoS Biology.
- (2018). The quaternary structure of human tyrosine hydroxylase: effects of dystonia‐associated missense variants on oligomeric state and enzyme activity. Journal of Neurochemistry. 291-306.
- (2018). Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases. EMBO Journal.
- (2017). Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase. BMC Biochemistry. 1-14.
- (2017). Rapid cadmium SAD phasing at the standard wavelength (1 Å). Acta Crystallographica Section D: Structural Biology. 581-590.
- (2017). Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proceedings of the National Academy of Sciences of the United States of America. 10636-10641.
- (2017). Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility. Journal of Biological Chemistry. 17857-17875.
- (2017). Apicomplexan actin polymerization depends on nucleation. Scientific Reports.
- (2017). A unique profilin-actin interface is important for malaria parasite motility. PLoS Pathogens.
- (2017). A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress. Science. 522-528.
- (2016). Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein. Journal of Cell Science. 1031-1045.
- (2016). An apicomplexan actin-binding protein serves as a connector and lipid sensor to coordinate motility and invasion. Cell Host and Microbe. 731-743.
- (2015). Two independently folding units of Plasmodium profilin suggest evolution via gene fusion. Cellular and Molecular Life Sciences (CMLS). 4193-4203.
- (2015). Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase. Scientific Reports.
More information in national current research information system (CRIStin)
Molecular mechanisms of parasite motility
Work in my research group is aimed at a mechanistic understanding of gliding motility, which malaria parasites and their relatives use for getting to and invading their host cells. We employ a broad range of biochemical, biophysical and hybrid structural biology methods for creating a complete molecular picture of the parasite actin-myosin motor and the entire glideosome. We also want to understand the evolution of apicomplexan gliding motility and eukaryotic actin-myosin motors in a broader sense. Understanding the mechanistic differences in cell motility between parasites and humans may, furthermore, open up new avenues for treatment and/or prevention of malaria.
We have determined atomic structures of malaria parasite actins in both monomeric and filamentous form and characterized their polymerization properties as well as nearly all the parasite actin-binding proteins known to date. Our future work is directed more towards larger complexes and reconstructing the entire parasite glideosome for structural and functional characterization.
My research group is divided between the Faculty of Biochemistry and Molecular Medicine at the University of Oulu, Finland, and the Department of Biomedicine, University of Bergen, Norway.
Personal details
Kursula, née Alavuotunki, Inari Talvikki
ORCID: 0000-0001-5236-7056
year of birth: 1974
married to Prof. Petri Kursula, 4 children (born 1994, 1997, 2000, 2006)
nationality: Finnish
Education and degrees completed
2013 Docent, Department of Biochemistry, University of Oulu, Finland
2003 PhD, Department of Biochemistry, University of Oulu, Finland
2001 MSc, Department of Biochemistry, University of Oulu, Finland
1992 Matriculation examination, Kastellin lukio, Oulu, Finland
Current positions
2015- Professor, Department of Biomedicine, University of Bergen, Norway
2021- Professor (10%), Faculty of Biochem. and Mol. Medicine, U. Oulu, Finland
Seleted grants
Sigrid Jusélius Foundation research grants (2009-2012, 2012-2014, 2015-2018, 2019-2022, 2022-2025)
Academy of Finland research grants (2010-2012, 2013-2015, 2015-2017, 2017-2021)
Norwegian Research Council research grant (2017-2020)
Jane and Aatos Erkko foundation research grant (2015-2017)
Emil Aaltonen foundation research grant (2015-2017)
Academy of Finland Research Fellow (2012-2017)
Academy of Finland post-doctoral researcher’s project grant (2008-2010)
European Commission Marie Curie European Reintegration Grant (2008-2010)
European Commission Marie Curie Intra-European Fellowship (2005-2007)
Academy of Finland personal post-doctoral grants (2003-2004)
Leadership and supervision experience
Ph.D. students supervised:
Gopinath Muruganandam, HZI / University of Hamburg, Ph.D. 2014
Saligram Prabhakar Bhargav, University of Oulu, Ph.D. 2014
Moon Chatterjee, HZI / University of Hamburg, Ph.D. 2015
Nele Vervaet, HZI / University of Hamburg, Ph.D. 2015
Esa-Pekka Kumpula, University of Oulu, Ph.D. 2019
Ábris Bendes, University of Oulu, Ph.D. 2021
Andrea Johana Lopez Móreno, University of Bergen, Ph.D. 2021
Isa Pires, University of Oulu, Ph.D. 2022
Atta Samoo, University of Oulu, Ph.D. 2022
Devaki Lasiwa, University of Oulu, Ph.D. examination estimated 2023
M.Sc. students supervised:
Bishal Singh, Dept. Biochemistry, University of Oulu, 2010
Emilia Pekkala, Dept. Biochemistry, University of Oulu, 2010
Jani Huttu, Dept. Biochemistry, University of Oulu, 2010
Katharina Höfler, Department of Chemistry, University of Hamburg, 2011
Ben Götte, University of Lübeck, 2014
Tiril Pedersen, University of Bergen, 2018
Maiken Fridal Trones, University of Bergen, 2022-2023
Jude Santhampillai, University of Oulu, 2022-2023
In addition, I have supervised >10 post-doctoral fellows and ~20 undergraduate students during short internships or B.Sc. thesis projects in Oulu, Hamburg, and Bergen.
Other key scientific or academic merits
Service in international expert peer-review committees etc:
2021 Chairperson of recruitment panel for Professor in Biomedicine, U. Bergen
2019-2022 Chairperson of the European XFEL Proposal Review Panel for the SPB/SFX instrument
2019-2025 Member of the Swiss FEL Proposal Review Committee
2018-2019 Vice chair of the Swedish Research Council Proposal Review Panel ‘Biochemistry and Structural Biology’
2017-2018 Member of recruitment panels for three post-doctoral fellowships, U. Bergen
2017-2022 Member of the European XFEL Proposal Review Panel for the SPB/SFX instrument
2017 Member of recruitment panel for Professor in Molecular Biology, U. Bergen
2017-2019 Member of the Swedish Research Council Proposal Review Panel ‘Biochemistry and Structural Biology’
Reviewer for grant applications for HFSP, Research Foundation Flanders, and MRC/BBSRC (UK)
Frequent reviewer for a number of scientific journals (e.g. PLoS ONE, FASEB J, FEBS Lett, Acta Cryst F, Acta Cryst D, J Mol Biol, Cytoskeleton, Biochimie, PLoS Pathog, Nature Microbiol, Mol Microbiol)
Key roles in international research projects or research infrastructures:
2016-2021 Board member of the BioCat Norwegian National Graduate School in Biocatalysis
2016-2019 Coordinator of the XBI User Consortium of the European XFEL
2015-2019 Representative of the University of Oulu in the XBI User Consortium (biological infrastructure related to the European XFEL)
2014-2021 Member of the Scientific Advisory Committee of the European XFEL
2014 Coordinator of the Finnish Research Infrastructure Roadmap application concerning the European XFEL/XBI
Service as pre-examiner or opponent of doctoral dissertations:
2021 Dissertation panel member of the Ph.D. thesis of Aseem Salhotra (Linnaeus U.)
2017 Reviewer of the Ph.D. thesis of Gergana Gateva (U. Helsinki)
2016 Member of the Ph.D. thesis dissertation committee of Theis Sommer (U. Oslo)
2015 Opponent in the Ph.D. defense of Helena Taberman (U. Eastern Finland)
2013-2016 Member of the Ph.D. thesis advisory committee of Joana Pereira (U. Hamburg/EMBL)
2012 Member of the Ph.D. thesis defense committee of Tim Wiegels (U. Hamburg/EMBL)
2012-2014 Member of the Ph.D. thesis advisory committee of Catherine Moreau (U. Heidelberg)
2011 Reviewer of the Ph.D. thesis of Heikki Takala (University of Jyväskylä)