Ingeborg Winge

Senior Engineer

E-mailIngeborg.Winge@uib.no
Phone+47 55 97 32 84+47 472 71 426
Visitor Address
Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
Postal Address
Postboks 7804

5020 Bergen

Academic article

2018. Structure of the mouse acidic amino acid decarboxylase GADL1. Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 65-73.
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2015. Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression. Neurochemistry International. 173-184.
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2013. Functional properties of rare missense variants of human CDH13 found in adult attention deficit/hyperactivity disorder (ADHD) patients. PLOS ONE. 9 pages.
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2010. Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2. Journal of Neurochemistry. 853-863.
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2010. Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production. Archives of General Psychiatry. 1033-1043.
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2009. Functional Properties of Missense Variants of Human Tryptophan Hydroxylase 2. Human Mutation. 787-794.
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2008. Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. Journal of Neurochemistry. 1648-1657.
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2008. Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5 '-region are associated with bipolar affective disorder. Human Molecular Genetics. 87-97.
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2008. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochemical Journal. 195-204.
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2007. Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. Journal of Neurochemistry. 1648-1657.
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2006. Characterization og wild-type and mutant forms of human trytopan hydroxylase 2. Journal of Neurochemistry. 10 pages.
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Academic lecture

2007. Common and rare variation in the gene for brain-expressed tryptophan hydroxylase 2 (TPH2) is associated with bipolar affective disorder in independent samples from Germany and Russia.
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1998. The effect of butyric acid on luciferase production in transfected CHO cells.
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Reader opinion piece

2008. A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention-deficit/hyperactivity disorder. Molecular Psychiatry. 365-367.
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Doctoral dissertation

2008. Human Tryptophan Hydroxylase 2; Regulatory properties and characterization of missense variants involved in neuropsychiatric disorders.
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Abstract

2010. PHARMACOLOGICAL CHAPERONES FOR THE AROMATIC AMINO ACID HYDROXYLASES. Journal of Inherited Metabolic Disease. S163-S163.
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2010. FUNCTIONAL STUDIES OF DISEASE-RELATED VARIANTS IN HUMAN TRYPTOPHAN HYDROXYLASE 1 AND 2. Journal of Inherited Metabolic Disease. S165-S165.
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2009. From synthesis to uptake - serotonergic genes in adult ADHD. European Neuropsychopharmacology. S186-S186.
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2005. Effects of mutations in human tryptophan hydroxylases associated with altered monoaminergic neurotransmission. Journal of Neurochemistry.
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2005. Biochemical characterization of mutant aromatic amino acid hydroxylases implicated in psychiatric disorders. American Journal of Medical Genetics.
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Poster

2007. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding.
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2005. Functional analysis of candidate genes and mutations involved in psychiatric disorders.
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2005. Expression and molecular characterization of human tryptophan hydroxylases.
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Academic literature review

2010. Functional studies of candidate genes involved in ADHD. 44-46.
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