Ingeborg Winge

Senior Engineer

E-mailIngeborg.Winge@uib.no
Phone+47 55 97 32 84+47 472 71 426
Visitor Address
Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
Postal Address
Postboks 7804

5020 Bergen

Academic article

Raasakka, Arne; Mahootchi, Elaheh; Winge, Ingeborg; Luan, Weisha; Kursula, Petri; Haavik, Jan. 2018. Structure of the mouse acidic amino acid decarboxylase GADL1. Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 65-73.

Winge, Ingeborg; Teigen, Knut; Fossbakk, Agnete; Mahootchi, Elaheh; Kleppe, Rune; Sköldberg, Filip; Kämpe, Olle; Haavik, Jan. 2015. Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression. Neurochemistry International. 173-184.

Mavroconstanti, Thegna; Johansson, Stefan; Winge, Ingeborg; Knappskog, Per; Haavik, Jan. 2013. Functional properties of rare missense variants of human CDH13 found in adult attention deficit/hyperactivity disorder (ADHD) patients. PLOS ONE. 9 pages.

Calvo, Ana C; Scherer, Tanja; Pey, Rodroguez Angel Luis; Ying, Ming; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Haavik, Jan; Thöny, Beat; Martinez, Aurora. 2010. Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2. Journal of Neurochemistry. 853-863.
Halmøy, Anne; Johansson, Stefan; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Knappskog, Per Morten; Haavik, Jan. 2010. Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production. Archives of General Psychiatry. 1033-1043.

Mckinney, Jeffrey Alan; Turel, Banu; Winge, Ingeborg; Knappskog, Per; Haavik, Jan. 2009. Functional Properties of Missense Variants of Human Tryptophan Hydroxylase 2. Human Mutation. 787-794.

Winge, Ingeborg; Mckinney, Jeffrey Alan; Knappskog, Per; Haavik, Jan. 2008. Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. Journal of Neurochemistry. 1648-1657.
Cichon, Sven; Winge, Ingeborg; Mattheisen, Manuel; Georgi, Alexander; Karpushova, Anna; Freudenberg, Jan; Freudenberg-Hua, Yun; Babadjanova, Gulia; Van Den Bogaert, Ann; Abramova, Lili I.; Kapiletti, Sofia; Knappskog, Per; Mckinney, Jeffrey Alan; Maier, Wolfgang; Abou Jamra, Rami; Schulze, Thomas G.; Schumacher, Johannes; Propping, Peter; Rietschel, Marcella; Haavik, Jan; Nöthen, Markus M. 2008. Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5 '-region are associated with bipolar affective disorder. Human Molecular Genetics. 87-97.
Winge, Ingeborg; Mckinney, Jeffrey; Ying, Ming; D Santos, Clive; Kleppe, Rune; Knappskog, Per; Haavik, Jan. 2008. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochemical Journal. 195-204.

Winge, Ingeborg; Mckinney, Jeffrey Alan; Knappskog, Per; Haavik, Jan. 2007. Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. Journal of Neurochemistry. 1648-1657.

Winge, Ingeborg; Mckinney, Jeffrey Alan; Knappskog, Per; Haavik, Jan. 2006. Characterization og wild-type and mutant forms of human trytopan hydroxylase 2. Journal of Neurochemistry. 10 pages.

Academic lecture

Cichon, S.; Knappskog, PM.; Babadjanova, G.; Karpushova, A.; Mattheisen, M.; Mühleisen, T. W.; Van Den Bogaert, A.; Freudenberg, J.; Freudenberg-Hua, Y.; Winge, Ingeborg; Mckinney, Jeffrey; Schumacher, J.; Abou Jamra, R.; Georgi, A.; Strohmaier, J.; Maier, W.; Schulze, T. G.; Propping, P.; Rieschel, M.; Haavik, Jan; Nöthen, M. M. 2007. Common and rare variation in the gene for brain-expressed tryptophan hydroxylase 2 (TPH2) is associated with bipolar affective disorder in independent samples from Germany and Russia.

Winge, Ingeborg; Johannessen, Arild; Pryme, Ian F; Hesketh, John E; Tauler, Albert. 1998. The effect of butyric acid on luciferase production in transfected CHO cells.

Reader opinion piece

Mckinney, Jeffrey; Johansson, Stefan; Halmøy, Anne; Dramsdahl, Margaretha; Winge, Ingeborg; Knappskog, Per; Haavik, Jan. 2008. A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention-deficit/hyperactivity disorder. Molecular Psychiatry. 365-367.

Doctoral dissertation

Winge, Ingeborg. 2008. Human Tryptophan Hydroxylase 2; Regulatory properties and characterization of missense variants involved in neuropsychiatric disorders.

Abstract

Martinez, Aurora; Calvo, Ana C; Scherer, Tanja; Pey, Rodroguez Angel Luis; Ying, Ming; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Haavik, Jan; Thöny, Beat. 2010. PHARMACOLOGICAL CHAPERONES FOR THE AROMATIC AMINO ACID HYDROXYLASES. Journal of Inherited Metabolic Disease. S163-S163.
Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Halmøy, Anne; Johansson, S; Knappskog, Per Morten; Haavik, Jan. 2010. FUNCTIONAL STUDIES OF DISEASE-RELATED VARIANTS IN HUMAN TRYPTOPHAN HYDROXYLASE 1 AND 2. Journal of Inherited Metabolic Disease. S165-S165.

Haavik, Jan; Johansson, Stefan; Knappskog, Per Morten; Winge, Ingeborg; McKinney, JA; Halmoy, A; Landaas, ET. 2009. From synthesis to uptake - serotonergic genes in adult ADHD. European Neuropsychopharmacology. S186-S186.

Winge, Ingeborg; Mckinney, Jeffrey Alan; Knappskog, Per; Haavik, Jan. 2005. Effects of mutations in human tryptophan hydroxylases associated with altered monoaminergic neurotransmission. Journal of Neurochemistry.
Haavik, Jan; Winge, Ingeborg; Mckinney, Jeffrey Alan; Knappskog, Per. 2005. Biochemical characterization of mutant aromatic amino acid hydroxylases implicated in psychiatric disorders. American Journal of Medical Genetics.

Poster

Winge, Ingeborg; Mckinney, Jeffrey; Ying, M.; D`Santos, C.; Kleppe, R.; Knappskog, PM.; Haavik, Jan. 2007. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding.

Haavik, Jan; Winge, Ingeborg; Mckinney, Jeffrey Alan. 2005. Functional analysis of candidate genes and mutations involved in psychiatric disorders.
Lundstad, Anne Christine; Winge, Ingeborg; Mckinney, Jeffrey Alan; Knappskog, Per; Haavik, Jan. 2005. Expression and molecular characterization of human tryptophan hydroxylases.

Academic literature review

Mavroconstanti, Thegna; Winge, Ingeborg; Mc Kinney, Jeffrey Alan; Knappskog, Per; Haavik, Jan. 2010. Functional studies of candidate genes involved in ADHD. 44-46.