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  • E-mailIvar.Hordvik@uib.no
  • Phone+47 55 58 45 38
  • Visitor Address
    Thormøhlensgt. 53 A/B
  • Postal Address
    Postboks 7803
    5020 Bergen

The research of Ivar Hordvik is focused on components of the adaptive immune system in fish. A long term goal is to broaden the spectrum of well characterized molecules and develop molecular tools that can be used to study immune responses during experiments with vaccines and pathogens in fish.

After teleost fish made a separate branch on the phylogenetic tree significant differences have been introduced between fish and mammals, both with respect to primary sequence of corresponding molecules, and the introduction of new molecules by gene duplications. An example of this is the evolution of the immunoglobulins: Whereas IgM has been evolutionarily stable and maintained the primordial structure in all jawed vertebrates the IgD gene has been evolutionarily labile and has been subjected to many internal duplications and deletions. A newly discovered gene, encoding an isotype named IgT/IgZ appears to be specific for teleost fish. On the other hand, IgG, IgE, and IgA are isotypes present in mammals, but not in fish.

Several findings the last years have shown that studies of the immune system in fish still offers surprises. It is plausible to assume that improved knowledge on the function and ontogeny of immune components in fish will aid experimental design of future vaccination trials and interpretation of results. Delivery of vaccines across mucosal surfaces of fish would obviously be an advantage and boost the profitability of the aquaculture industry. Development of new reagents for identification of immune cells and for monitoring immune responses is also an issue which has been addressed by vaccine companies as well as many researchers.

Journal articles
  • Bilal, Sumaira; Lie, Kai Kristoffer; Dalum, Alf Seljenes; Karlsen, Odd Andre; Hordvik, Ivar. 2019. Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. Fish and Shellfish Immunology. 87: 650-658. doi: 10.1016/j.fsi.2019.02.007
  • Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind; Hordvik, Ivar; Dalmo, Roy Ambli; Seternes, Tore. 2019. Intramuscular vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) induces inflammatory reactions and local immunoglobulin M production at the vaccine administration site. Journal of Fish Diseases. 13 pages. doi: https://doi.org/10.1111/jfd.13101
  • Bilal, Sumaira; Lie, Kai Kristoffer; Sæle, Øystein; Hordvik, Ivar. 2018. T cell receptor alpha chain genes in the teleost Ballan wrasse (Labrus bergylta) are subjected to somatic hypermutation. Frontiers in Immunology. 9:1101: 1-11. doi: 10.3389/fimmu.2018.01101
  • Bjørgen, Håvard; Koppang, Erling Olaf; Gunnes, Gjermund; Hordvik, Ivar; Moldal, Torfinn; Kaldhusdal, Magne; Dale, Ole Bendik. 2018. Ectopic epithelial cell clusters in salmonid intestine are associated with inflammation. Journal of Fish Diseases. 41: 1031-1040. Published 2018-03-23. doi: 10.1111/jfd.12780
  • Aas, Ida Bergva; Austbø, Lars; Falk, Knut; Hordvik, Ivar; Koppang, Erling Olaf. 2017. The interbranchial lymphoid tissue likely contributes to immune tolerance and defense in the gills of Atlantic salmon. Developmental and Comparative Immunology. 76: 247-254. doi: 10.1016/j.dci.2017.06.013
  • Erkinharju, Toni; Dalmo, Roy Ambli; Vågsnes, Øyvind; Hordvik, Ivar; Seternes, Tore. 2017. Vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) at a low temperature leads to a low antibody response against Aeromonas salmonicida. Journal of Fish Diseases. 41: 613-623. doi: 10.1111/jfd.12760
  • Erkinharju, Toni; Lundberg, Martin, Rønbeck; Isdal, Eivind; Hordvik, Ivar; Dalmo, Roy Ambli; Seternes, Tore. 2017. Studies on the antibody response and side effects after intramuscular and intraperitoneal injection of Atlantic lumpfish (Cyclopterus lumpus L.) with different oil-based vaccines. Journal of Fish Diseases. 40: 1805-1813. doi: 10.1111/jfd.12649
  • Bilal, Sumaira; Lie, Kai Kristoffer; Karlsen, Odd Andre; Hordvik, Ivar. 2016. Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). Fish and Shellfish Immunology. 59: 9-17. doi: 10.1016/j.fsi.2016.09.063
  • Dalum, Alf Seljenes; Tangen, Randi; Falk, Knut; Hordvik, Ivar; Rosenlund, Grethe; Torstensen, Bente Elisabeth; Koppang, Erling Olaf. 2016. Coronary changes in the Atlantic salmon Salmo salar L: characterization and impact of dietary fatty acid compositions. Journal of Fish Diseases. 39: 41-54. doi: 10.1111/jfd.12321
  • Dalum, Alf Seljenes; Austbø, Lars; Bjørgen, Håvard; Skjødt, Karsten; Hordvik, Ivar; Hansen, Tom Johnny; Fjelldal, Per Gunnar; Press, Charles McLean; Griffiths, David; Koppang, Erling Olaf. 2015. The interbranchial lymphoid tissue of Atlantic Salmon (Salmo salar L) extends as a diffuse mucosal lymphoid tissue throughout the trailing edge of the gill filament. Journal of morphology. 276: 1075-1088. doi: 10.1002/jmor.20403
  • Hordvik, Ivar. 2015. Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar. Biomolecules. 5: 166-177. doi: 10.3390/biom5010166
  • Aas, Ida Bergva; Austbø, Lars; Kønig, Melanie; Syed, Mohasina; Falk, Knut; Hordvik, Ivar; Koppang, Erling Olaf. 2014. Transcriptional characterization of the T cell population within the salmonid interbranchial lymphoid tissue. Journal of Immunology. 193: 3463-3469. doi: 10.4049/​jimmunol.1400797
  • Hordvik, Ivar. 2014. Laksen har dobbelt sett med gener (INNSIKT-artikkel). Bergens Tidende. 14-15. Published 2014-01-24.
  • Løkka, Guro; Austbø, Lars; Falk, Knut; Bromage, Erin; Fjelldal, Per Gunnar; Hansen, Tom Johnny; Hordvik, Ivar; Koppang, Erling Olaf. 2014. Immune parameters in the intestine of wild and reared unvaccinated and vaccinated Atlantic salmon (Salmo salar L.). Developmental and Comparative Immunology. 47: 6-16. doi: 10.1016/j.dci.2014.06.009
  • Aas, Ida Bergva; Austbø, Lars; Kønig, Melanie; Syed, Mohasina; Hordvik, Ivar; Falk, Knut; Koppang, Erling Olaf. 2013. The immunological function of the interbranchial lymphoid tissue (ILT). Fish and Shellfish Immunology. 34: 1636-1636.
  • Frøyse, Alf Lars Dalum; Thorsen, Jim; Austbø, Lars; Press, Charles; Hordvik, Ivar; Koppang, Erling Olaf. 2013. Anatomy of the interbranchial lymphoid tissue (ILT) in salmonid fish. Fish and Shellfish Immunology. 34: 1651-1651. doi: 10.1016/j.fsi.2013.03.053
  • Hordvik, Ivar; Kamil, Atif; Bilal, Sumaira; Raae, Arnt Johan; Fjelldal, Per Gunnar; Koppang, Erling Olaf. 2013. Characterization of serum IgM in teleost fish, with emphasis on salmonids. Fish and Shellfish Immunology. 34: 1656-1656. doi: 10.1016/j.fsi.2013.03.067
  • Kamil, Atif; Fjelldal, Per Gunnar; Hansen, Tom Johnny; Raae, Arnt Johan; Koppang, Erling Olaf; Hordvik, Ivar. 2013. VACCINATION of Atlantic salmon leads to long-lasting higher levels of serum immunoglobulin and possible skewed ratios of two distinct IgM isotypes. Advances in Bioscience and Biotechnology. 4: 85-90. doi: 10.4236/abb.2013.44A012
  • Kamil, Atif; Raae, Arnt Johan; Fjelldal, Per Gunnar; Koppang, Erling Olaf; Fladmark, Kari Espolin; Hordvik, Ivar. 2013. Comparative analysis of IgM sub-variants in salmonid fish and identification of a residue in mu 3 which is essential for MAb4C10 reactivity. Fish and Shellfish Immunology. 34: 667-672. doi: 10.1016/j.fsi.2012.12.006
  • Løkka, Guro; Austbø, Lars; Falk, Knut; Hordvik, Ivar; Koppang, Erling Olaf. 2013. Expression of immune related genes in the Atlantic salmon intestine. Fish and Shellfish Immunology. 34: 1662-1662.
  • Yousaf, Muhammed; Koppang, Erling Olaf; Skjødt, Karsten; Hordvik, Ivar; Zou, Jun; Secombes, Chris; Powell, Mark Darryn. 2013. Comparative cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD). Veterinary Immunology and Immunopathology. 151: 49-62. doi: 10.1016/j.vetimm.2012.10.004
  • Larsen, Hilde; Austbø, Lars; Mørkøre, Turid; Thorsen, Jim; Hordvik, Ivar; Fischer, Uwe; Jirillo, Emilio; Rimstad, Espen; Koppang, Erling Olaf. 2012. Pigment-producing granulomatous myopathy in Atlantic salmon: A novel inflammatory response. Fish and Shellfish Immunology. 33: 277-285. doi: 10.1016/j.fsi.2012.05.012
  • Wiik-Nielsen, Jannicke; Løvoll, Marie Therese; Fritsvold, Camilla; Kristoffersen, Anja Bråthen; Haugland, Øyvind; Hordvik, Ivar; Aamelfot, Maria; Jirillo, Emilio; Koppang, Erling Olaf; Grove, Søren. 2012. Characterization of myocardial lesions associated with cardiomyopathy syndrome in Atlantic salmon, Salmo salar L., using laser capture microdissection. Journal of Fish Diseases. 35: 907-916. doi: 10.1111/j.1365-2761.2012.01431.x
  • Yousaf, Muhammed; Koppang, Erling Olaf; Skjødt, Karsten; Köllner, Bernd; Hordvik, Ivar; Zou, Jun; Secombes, Chris; Powell, Mark Darryn. 2012. Cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI). Fish and Shellfish Immunology. 33: 305-315. doi: 10.1016/j.fsi.2012.05.008
  • Hordvik, Ivar; Mortensen, Stein. 2011. Ville reinsdyr trives best. Bergens Tidende. 28-28. Published 2011-08-25.
  • Kamil, Atif; Falk, Knut; Sharma, Animesh; Raae, Arnt Johan; Berven, Frode; Koppang, Erling Olaf; Hordvik, Ivar. 2011. A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. Molecular Immunology. doi: 10.1016/j.molimm.2011.05.005
  • Tadiso, Tariku Markos; Krasnov, Aleksei; Skugor, Stanko; Afanasyev, Sergey; Hordvik, Ivar; Nilsen, Frank. 2011. Gene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition. BMC Genomics. 12. 17 pages. doi: 10.1186/1471-2164-12-141
  • Tadiso, Tariku Markos; Lie, Kai Kristoffer; Hordvik, Ivar. 2011. Molecular cloning of IgT from Atlantic salmon, and analysis of the relative expression of tau, mu, and delta in different tissues. Veterinary Immunology and Immunopathology. 139: 17-26. doi: 10.1016/j.vetimm.2010.07.024
  • Tadiso, Tariku Markos; Sharma, Animesh; Hordvik, Ivar. 2011. Analysis of polymeric immunoglobulin receptor- and CD300-like molecules from Atlantic salmon. Molecular Immunology. 49: 462-473. Published 2011-12-01. doi: 10.1016/j.molimm.2011.09.013
  • Koppang, Erling Olaf; Fischer, Uwe; Moore, Lindsey; Tranulis, Michael Andreas; Dijkstra, Johannes Martinus; Köllner, Bernd; Aune, Laila; Jirillo, Emilio; Hordvik, Ivar. 2010. Salmonid T cells assemble in the thymus, spleen and in novel interbranchial lymphoid tissue. Journal of Anatomy. 217: 728-739. doi: 10.1111/j.1469-7580.2010.01305.x
  • Moore, Lindsey; Dijkstra, J.M; Koppang, Erling Olaf; Hordvik, Ivar. 2009. CD4 homologues in Atlantic salmon. Fish and Shellfish Immunology. 26: 10-18.
  • Moore, Lindsey; Dijkstra, Johannes Martinus; Koppang, Erling Olaf; Hordvik, Ivar. 2009. CD4 homologues in Atlantic salmon. Fish and Shellfish Immunology. 26: 10-18. doi: 10.1016/j.fsi.2008.09.019
  • Øvergård, Aina-Cathrine; Hordvik, Ivar; Nerland, Audun H.; Eikeland, Gisle; Patel, Sonal. 2009. Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes. Fish and Shellfish Immunology. 27: 707-713. doi: 10.1016/j.fsi.2009.08.011
  • Haugarvoll, Erlend; Bjerkås, Inge; Nowak, BF; Hordvik, Ivar; Koppang, Erling Olaf. 2008. Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. Journal of Anatomy. 213: 202-209.
  • Haugarvoll, Erlend; Bjerkås, Inge; Nowak, Barbara F.; Hordvik, Ivar; Koppang, Erling Olaf. 2008. Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. Journal of Anatomy. 213: 202-209. doi: 10.1111/j.1469-7580.2008.00943.x
  • Liu, Yun; Moore, Lindsey; Koppang, Erling Olaf; Hordvik, Ivar. 2008. Characterization of the CD3f, CD3cd and CD3e subunits of the T cell receptor complex in Atlantic salmon. Developmental and Comparative Immunology. 32: 26-35.
  • Liu, Yun; Moore, Lindsey; Koppang, Erling Olaf; Hordvik, Ivar. 2008. Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon. Developmental and Comparative Immunology. 32: 26-35. doi: 10.1016/j.dci.2007.03.015
  • Dijkstra, Johannes Martinus; Somamoto, Tomonori; Moore, Lindsey; Hordvik, Ivar; Ototake, Mitsuru; Fischer, Uwe. 2006. Identification and characterization of a second CD4-like gene in teleost fish. Molecular Immunology. 43: 410-419. doi: 10.1016/j.molimm.2005.03.005
  • Hevrøy, Ernst Morten; Jordal, Ann-Elise Olderbakk; Hordvik, Ivar; Espe, Marit; Hemre, Gro Ingunn; Olsvik, Pål A. 2006. Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar. Aquaculture. 252: 453-461. doi: Sesammendrag
  • Morrison, RN; Koppang, Erling Olaf; Hordvik, Ivar; Nowak, BF. 2006. MHC class ll+ cells in the gills of Atlantic salmon ( Salmo salar L.) affected by amoebic gill disease. Veterinary Immunology and Immunopathology. 15: 297-303.
  • Morrison, Richard N.; Koppang, Erling Olaf; Hordvik, Ivar; Nowak, Barbara F. 2006. MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease. Veterinary Immunology and Immunopathology. 109: 297-303. doi: 10.1016/j.vetimm.2005.08.026
  • Fischer, Uwe; Dijkstra, J.M; Kollner, B; Kiryu, I; Koppang, Erling Olaf; Hordvik, Ivar; Sawamoto, Y; Ototake, M. 2005. The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). Fish and Shellfish Immunology. 18: 49-60.
  • Fischer, Uwe; Dijkstra, Johannes Martinus; Köllner, Bernd; Kiryu, Ikunari; Koppang, Erling Olaf; Hordvik, Ivar; Sawamoto, Yoshihiro; Ototake, Mitsuru. 2005. The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). Fish and Shellfish Immunology. 18: 49-60.
  • Koppang, Erling Olaf; Haugarvoll, E; Hordvik, Ivar; Aune, L; Poppe, TT. 2005. Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. Journal of Fish Diseases. 28.
  • Koppang, Erling Olaf; Haugarvoll, Erlend; Hordvik, Ivar; Aune, Laila; Poppe, Trygve. 2005. Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. Journal of Fish Diseases. 28: 13-22.
  • Moore, LJ; Somamoto, T; Lie, KK; Dijkstra, JM; Hordvik, Ivar. 2005. Characterisation of salmon and trout CD8 alpha and CD8 beta. Molecular Immunology. 42.
  • Olsvik, Pål A.; Lie, Kai Kristoffer; Olderbakk Jordal, Anne-Lise; Nilsen, Tom Ole; Hordvik, Ivar. 2005. Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon. BMC Molecular Biology. 6: 1-9. doi: 10.1186/1471-2199-6-21
  • Van Do, Thien; Elsayed, Said; Florvaag, Erik; Hordvik, Ivar; Endresen, Curt. 2005. Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish. Journal of Allergy and Clinical Immunology. 116: 1314-1320. doi: 10.1016/j.jaci.2005.07.033
  • Van Do, Thien; Hordvik, Ivar; Endresen, Curt; Elsayed, Said. 2005. Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M. Molecular Immunology. 42: 345-353. doi: 10.1016/j.molimm.2004.09.001
  • Hordvik, Ivar; Torvund, Jannicke; Moore, Lindsey; Endresen, Curt. 2004. Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon. Molecular Immunology. 41: 553-559.
  • Koppang, Erling Olaf; Haugarvoll, E; Hordvik, Ivar; Poppe, TT; Bjerkas, I. 2004. Granulomatous uveitis associated with vaccination in the Atlantic salmon. Veterinary pathology. 41: 122-130.
  • Koppang, Erling Olaf; Haugarvoll, Erlend; Hordvik, Ivar; Poppe, Trygve; Bjerkås, Inge. 2004. Granulomatous uveitis associated with vaccination in the Atlantic salmon. Veterinary pathology. 41: 122-130.
  • Koppang, Erling Olaf; Bjerkås, Ellen; Bjerkås, Inge; Sveier, H; Hordvik, Ivar. 2003. Vaccination Induces Major Histocompatibility Complex Class II Expression in the Atlantic Salmon Eye. Scandinavian Journal of Immunology. 58: 9-14.
  • Koppang, Erling Olaf; Bjerkås, Ellen; Bjerkås, Inge; Sveier, Harald; Hordvik, Ivar. 2003. Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye. Scandinavian Journal of Immunology. 58: 9-14.
  • Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge; Torvund, J; Aune, Laila; Thevarajan, J; Endresen, Curt. 2003. Production of rabbit antisera against recombinant MHC class II B chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). Fish and Shellfish Immunology. 14: 115-132.
  • Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge; Torvund, Jannicke; Aune, Laila; Thevarajan, Jegathes; Endresen, Curt. 2003. Production of rabbit antisera against recombinant MHC class II beta chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). Fish and Shellfish Immunology. 14: 115-132.
  • Hordvik, Ivar. 2002. Identification of a novel immunoglobulin δ transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut. Molecular Immunology. 39: 85-91.
  • Hordvik, Ivar; Berven, Frode; Solem, Stein Tore; Hatten, Frode; Endresen, Curt. 2002. Analysis of two IgM isotypes in Atlantic salmon and brown trout. Molecular Immunology. 39: 313-321.
  • Hordvik, Ivar; Koppang, Erling Olaf. 2002. Karakterisering av immungener hos fisk. Litt historikk, status og fremtidsutsikter. Fiskehelse. 1.
  • Hatten, Frode; Fredriksen, Åse; Hordvik, Ivar; Endresen, Curt. 2001. Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus. Fish and Shellfish Immunology. 11: 257-268.
  • Solem, Stein T.; Hordvik, Ivar; Killie, Jan-Eirik A.; Warr, Gregory W.; Jørgensen, Trond Ø. 2001. Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci. Developmental and Comparative Immunology. 25: 403-417.
  • Do, Thien van; Hordvik, Ivar; Endresen, Curt; Elsayed, Said. 1999. Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). ?. 50: 619-625.
  • Hordvik, Ivar. 1999. En nyoppdaget type antistoffer hos beinfisk. Fiskehelse. 2. 17-21.
  • Hordvik, Ivar; Thevarajan, J.; Samdal, I.; Bastani, N.; Krossøy, B. 1999. Molecular cloning and phylogenetic analysis of the Atlantic salmon Immunoglobulin D gene. Scandinavian Journal of Immunology. 50: 202-210.
  • Krossøy, Bjørn; Hordvik, Ivar; Nilsen, Frank; Nylund, Are; Endresen, Curt. 1999. The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae. Journal of Virology. 73: 2136-2142.
  • Van Do, Thien; Hordvik, Ivar; Endresen, Curt; Elsayed, S. 1999. Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). Scandinavian Journal of Immunology. 50: 619-625.
  • Hordvik, Ivar. 1998. The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes. Immunological Reviews. 116: 153-157.
  • Nilsen, Frank; Endresen, Curt; Hordvik, Ivar. 1998. Molecular phylogeny of mcrosoridians with particular reference to species that infect the muscles of fish. Journal of Eukaryotic Microbiology. 45: 535-543.
  • Hordvik, Ivar; Lindstrøm, Christian De Vries; Voie, Ann-Mari; Jacob, Anne Lilybert J.; Endresen, Curt. 1997. Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar. Molecular Immunology. 34: 631-639.
  • Van Do, Thien; Hordvik, Ivar; Endresen, Curt; Elsayed, Said. 1997. cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). Allergy. European Journal of Allergy and Clinical Immunology. 37: 49.
  • Van, Dô; Hordvik, Ivar; Endresen, Curt; Elsayed, Said. 1997. cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). Allergy. European Journal of Allergy and Clinical Immunology. 37: 49.
  • Elsayed, Said; Lindstrøm, c.d-v; Van Do, Thien; Hordvik, Ivar; Endresen, Curt. 1996. Cloning of two distinct cDNA encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). Allergy. European Journal of Allergy and Clinical Immunology. 51: 139.
  • Hordvik, Ivar; Jacob, Anne Lilybert J.; Charlemagne, Jacques; Endresen, Curt. 1996. Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar). Immunogenetics. 45: 9-14.
  • Lindstrøm, Christian De Vries; Van Do, Thien; Hordvik, Ivar; Endresen, Curt; Elsayed, Said. 1996. Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). Scandinavian Journal of Immunology. 44: 335-344.
  • Nylund, Are; Hordvik, Ivar; Endresen, Curt. 1996. Avl og sykdomsresistens. Norsk Fiskeoppdrett. 22: 25-27.
  • Hordvik, Ivar. 1994. Immune genes of the Atlantic salmon. Application of modern genetic techniques to the study of antibodies and MHC antigens from Atlantic salmon. Aquaculture and Fisheries Management. 25: 47-53.
  • Lie, Ø.; Slettan, A.; Lingaas, F.; Olsaker, I.; Hordvik, Ivar; Refslie, I. 1994. Haploid gynogenesis. A powerful strategy for linkage analysis in fish. Animal Biotechnology.
  • Grimholt, U.; Hordvik, Ivar; Fosse, Vivian Jacobsen; Olsaker, I.; Endresen, Curt; Lie, Ø. 1993. Molecular cloning of major histocompability complex class I cDNAs from Atlantic salmon (Salmo salar). Immunogenetics. 37: S. 469-473.
  • Hordvik, Ivar; Grimholt, Unni; Fosse, Viggo M.; Lie, Øystein; Endresen, Curt. 1993. Cloning and sequence analysis of cDNAs encoding the MHC class II beta chain in Atlantic salmon (Salmo salar). Immunogenetics. 37: 437-441.
  • Hordvik, Ivar; Voie, A. M.; Glette, J.; Male, M.; Endresen, Curt. 1992. Cloning and sequence analysis of two isotopic IgM heavy chain genes from Atlantic salmon, Salmo salar L. European Journal of Immunology. 22: 2957-2962.
  • Molven, Anders; Hordvik, Ivar; Njølstad, Pål Rasmus; Gheulue, M. van; Fjose, Anders. 1992. The zebrafish homeobox gene Hox(zf-114): primary structure, expression pattern and evolutionary aspects. International Journal of Developmental Biology. 36: 229-237.
Reports and theses
  • Hordvik, Ivar. 1993. Immune genes of the Atlantic salmon. Cloning and sequence analyses of genes encoding the IgM heavy chain, the MHC class I alpha-chain and the MHC class II beta-chain. 72 pages.
Book sections
  • Robertsen, Børre; Hordvik, Ivar; Jørgensen, Trond Ø. 2007. The fish immune system. kapittel, pages 185-197. In:
    • Thomassen, Magny; Gudding, Roar; Norberg, Birgitta; Jørgensen, Leif. 2007. Aquaculture Research: From cage to consumption. ISBN: 978-82-12-02408-3.
  • Robertsen, Børre; Hordvik, Ivar; Jørgensen, Trond Ø. 2006. Immunsystemet hos fisk. kapittel, pages 176-188. In:
    • Thomassen, Magny; Gudding, Roar; Norberg, Birgitta; Jørgensen, Leif. 2006. Havbruksforskning: Fra merd til mat. Norges forskningsråd. 373 pages. ISBN: 82-12-02277-3.

More information in national current research information system (CRIStin)

Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes
Author(s): Overgard, AC; Hordvik, I; Nerland, AH, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 27   Issue: 6   Pages: 707-713   Published: 2009

 

CD4 homologues in Atlantic salmon
Author(s): Moore, LJ; Dijkstra, JM; Koppang, EO, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 26   Issue: 1   Pages: 10-18   Published: 2009

 

Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon
Author(s): Haugarvoll, E; Bjerkas, I; Nowak, BF, et al.
Source: JOURNAL OF ANATOMY   Volume: 213   Issue: 2   Pages: 202-209   Published: 2008

 

Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon
Author(s): Liu, Y; Moore, L; Koppang, EO, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY   Volume: 32   Issue: 1   Pages: 26-35   Published: 2008

 

FABP3 and FABP10 in Atlantic salmon (Salmo salar L.) - General effects of dietary fatty acid composition and life cycle variations
Author(s): Jordal, AEO; Hordvik, I; Pelsers, M, et al.
Source: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   Volume: 145   Issue: 2   Pages: 147-158   Published: OCT 2006

 

Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar
Author(s): Hevroy, EM; Jordal, AEO; Hordvik, I, et al.
Source: AQUACULTURE   Volume: 252   Issue: 2-4   Pages: 453-461   Published: MAR 10 2006

 

Identification and characterization of a second CD4-like gene in teleost fish
Author(s): Dijkstra, JM; Somamoto, T; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 43   Issue: 5   Pages: 410-419   Published: FEB 2006

 

MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease
Author(s): Morrison, RN; Koppang, EO; Hordvik, I, et al.
Source: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY   Volume: 109   Issue: 3-4   Pages: 297-303   Published: FEB 15 2006

 

Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish
Author(s): Van Do, T; Elsayed, S; Florvaag, E, et al.
Source: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Volume: 116   Issue: 6   Pages: 1314-1320   Published: DEC 2005

 

Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon
Author(s): Olsvik, PA; Lie, KK; Jordal, AEO, et al.
Source: BMC MOLECULAR BIOLOGY   Volume: 6   Article Number: 21   Published: NOV 17 2005

 

Characterisation of salmon and trout CD8 alpha and CD8 beta
Author(s): Moore, LJ; Somamoto, T; Lie, KK, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 42   Issue: 10   Pages: 1225-1234   Published: JUN 2005

 

Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 42   Issue: 3   Pages: 345-353   Published: FEB 2005

 

The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss)
Author(s): Fischer, U; Dijkstra, JM; Kollner, B, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 18   Issue: 1   Pages: 49-60   Published: JAN 2005

 

Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: JOURNAL OF FISH DISEASES   Volume: 28   Issue: 1   Pages: 13-22   Published: JAN 2005

 

Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon
Author(s): Hordvik, I; Torvund, J; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 41   Issue: 5   Pages: 553-559   Published: JUL 2004

 

Granulomatous uveitis associated with vaccination in the Atlantic salmon
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: VETERINARY PATHOLOGY   Volume: 41   Issue: 2   Pages: 122-130   Published: MAR 2004

 

Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye
Author(s): Koppang, EO; Bjerkas, E; Bjerkas, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 58   Issue: 1   Pages: 9-14   Published: JUL 2003

 

The major allergen (parvalbumin) of codfish is encoded by at least two isotypic genes: cDNA cloning, expression and antibody binding of the recombinant allergens
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 10   Pages: 595-602   Published: JAN 2003

 

Analysis of two IgM isotypes in Atlantic salmon and brown trout
Author(s): Hordvik, I; Berven, FS; Solem, ST, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 5-6   Pages: 313-321   Published: OCT 2002

 

Identification of a novel immunoglobulin delta transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut
Author(s): Hordvik, I
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 1-2   Pages: 85-91   Published: SEP 2002

 

Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci.
Author(s): Solem, ST; Hordvik, I; Killie, JEA, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY   Volume: 25   Issue: 5-6   Pages: 403-417   Published: JUN-JUL 2001

 

Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus
Author(s): Hatten, F; Fredriksen, A; Hordvik, I, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 11   Issue: 3   Pages: 257-268   Published: APR 2001

 

Expression and analysis of recombinant salmon parvalbumin, the major allergen in atlantic salmon (Salmo salar)
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 50   Issue: 6   Pages: 619-625   Published: 1999

 

Molecular cloning and phylogenetic analysis of the Atlantic salmon immunoglobulin D gene
Author(s): Hordvik, I; Thevarajan, J; Samdal, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 50   Issue: 2   Pages: 202-210   Published: AUG 1999

 

The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae
Author(s): Krossoy, B; Hordvik, I; Nilsen, F, et al.
Source: JOURNAL OF VIROLOGY   Volume: 73   Issue: 3   Pages: 2136-2142   Published: MAR 1999

 

The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes
Author(s): Hordvik, I
Source: IMMUNOLOGICAL REVIEWS   Volume: 166   Pages: 153-157   Published: DEC 1998

 

Molecular phylogeny of microsporidians with particular reference to species that infect the muscles of fish
Author(s): Nilsen, F; Endresen, C; Hordvik, I
Source: JOURNAL OF EUKARYOTIC MICROBIOLOGY   Volume: 45   Issue: 5   Pages: 535-543   Published: SEP-OCT 1998

 

Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar
Author(s): Hordvik, I; Lindstrom, CD; Voie, AM, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 34   Issue: 8-9   Pages: 631-639   Published: JUN 1997

 

Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar)
Author(s): Hordvik, I; Jacob, ALJ; Charlemagne, J, et al.
Source: IMMUNOGENETICS   Volume: 45   Issue: 1   Pages: 9-14   Published: 1996

 

Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar)
Author(s): Lindstrom, CDV; VanDo, T; Hordvik, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 44   Issue: 4   Pages: 335-344   Published: OCT 1996

 

Immune genes of the Atlantic salmon, Salmo salar L.: Application of modern molecular genetic techniques to the study of antibodies and major histocompatibility complex antigens
Author(s): Hordvik, I.
Source: Aquaculture and Fisheries Management   Volume: 25   Issue: 1   Pages: 47-53   Published: 1994

 

Haploid gynogenesis: A powerful strategy for linkage analysis in fish
Author(s): Lie, O.; Slettan, A.; Lingaas, F., et al.
Source: Animal Biotechnology   Volume: 5   Issue: 1   Pages: 33-45   Published: 1994

 

MOLECULAR-CLONING OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I CDNAS FROM ATLANTIC SALMON (SALMO-SALAR)
Author(s): GRIMHOLT, U; HORDVIK, I; FOSSE, VM, et al.
Source: IMMUNOGENETICS   Volume: 37   Issue: 6   Pages: 469-473   Published: FEB 1993

 

CLONING AND SEQUENCE-ANALYSIS OF CDNAS ENCODING THE MHC CLASS-II BETA-CHAIN IN ATLANTIC SALMON (SALMO-SALAR)
Author(s): HORDVIK, I; GRIMHOLT, U; FOSSE, VM, et al.
Source: IMMUNOGENETICS   Volume: 37   Issue: 6   Pages: 437-441   Published: FEB 1993

 

CLONING AND SEQUENCE-ANALYSIS OF 2 ISOTYPIC IGM HEAVY-CHAIN GENES FROM ATLANTIC SALMON, SALMO-SALAR L
Author(s): HORDVIK, I; VOIE, AM; GLETTE, J, et al.
Source: EUROPEAN JOURNAL OF IMMUNOLOGY   Volume: 22   Issue: 11   Pages: 2957-2962   Published: NOV 1992