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  • E-mailIvar.Hordvik@uib.no
  • Phone+47 55 58 45 38
  • Visitor Address
    Thormøhlensgt. 53 A/B
  • Postal Address
    Postboks 7803
    5020 Bergen

The research of Ivar Hordvik is focused on components of the adaptive immune system in fish. A long term goal is to broaden the spectrum of well characterized molecules and develop molecular tools that can be used to study immune responses during experiments with vaccines and pathogens in fish.

After teleost fish made a separate branch on the phylogenetic tree significant differences have been introduced between fish and mammals, both with respect to primary sequence of corresponding molecules, and the introduction of new molecules by gene duplications. An example of this is the evolution of the immunoglobulins: Whereas IgM has been evolutionarily stable and maintained the primordial structure in all jawed vertebrates the IgD gene has been evolutionarily labile and has been subjected to many internal duplications and deletions. A newly discovered gene, encoding an isotype named IgT/IgZ appears to be specific for teleost fish. On the other hand, IgG, IgE, and IgA are isotypes present in mammals, but not in fish.

Several findings the last years have shown that studies of the immune system in fish still offers surprises. It is plausible to assume that improved knowledge on the function and ontogeny of immune components in fish will aid experimental design of future vaccination trials and interpretation of results. Delivery of vaccines across mucosal surfaces of fish would obviously be an advantage and boost the profitability of the aquaculture industry. Development of new reagents for identification of immune cells and for monitoring immune responses is also an issue which has been addressed by vaccine companies as well as many researchers.

Academic article
  • 2019. Intramuscular vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) induces inflammatory reactions and local immunoglobulin M production at the vaccine administration site. Journal of Fish Diseases. 1731-1743.
  • 2019. Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. Fish and Shellfish Immunology. 650-658.
  • 2019. A teleost structural analogue to the avian bursa of Fabricius. Journal of Anatomy. 1-11.
  • 2018. T cell receptor alpha chain genes in the teleost Ballan wrasse (Labrus bergylta) are subjected to somatic hypermutation. Frontiers in Immunology. 1-11.
  • 2018. Ectopic epithelial cell clusters in salmonid intestine are associated with inflammation. Journal of Fish Diseases. 1031-1040.
  • 2017. Vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) at a low temperature leads to a low antibody response against Aeromonas salmonicida. Journal of Fish Diseases. 613-623.
  • 2017. The interbranchial lymphoid tissue likely contributes to immune tolerance and defense in the gills of Atlantic salmon. Developmental and Comparative Immunology. 247-254.
  • 2017. Studies on the antibody response and side effects after intramuscular and intraperitoneal injection of Atlantic lumpfish (Cyclopterus lumpus L.) with different oil-based vaccines. Journal of Fish Diseases. 1805-1813.
  • 2016. Coronary changes in the Atlantic salmon Salmo salar L: characterization and impact of dietary fatty acid compositions. Journal of Fish Diseases. 41-54.
  • 2016. Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). Fish and Shellfish Immunology. 9-17.
  • 2015. The interbranchial lymphoid tissue of Atlantic Salmon (Salmo salar L) extends as a diffuse mucosal lymphoid tissue throughout the trailing edge of the gill filament. Journal of morphology. 1075-1088.
  • 2015. Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar. Biomolecules. 166-177.
  • 2014. Transcriptional characterization of the T cell population within the salmonid interbranchial lymphoid tissue. Journal of Immunology. 3463-3469.
  • 2014. Immune parameters in the intestine of wild and reared unvaccinated and vaccinated Atlantic salmon (Salmo salar L.). Developmental and Comparative Immunology. 6-16.
  • 2013. Comparative cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD). Veterinary Immunology and Immunopathology. 49-62.
  • 2013. Comparative analysis of IgM sub-variants in salmonid fish and identification of a residue in mu 3 which is essential for MAb4C10 reactivity. Fish and Shellfish Immunology. 667-672.
  • 2012. Pigment-producing granulomatous myopathy in Atlantic salmon: A novel inflammatory response. Fish and Shellfish Immunology. 277-285.
  • 2012. Characterization of myocardial lesions associated with cardiomyopathy syndrome in Atlantic salmon, Salmo salar L., using laser capture microdissection. Journal of Fish Diseases. 907-916.
  • 2012. Cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI). Fish and Shellfish Immunology. 305-315.
  • 2011. Molecular cloning of IgT from Atlantic salmon, and analysis of the relative expression of tau, mu, and delta in different tissues. Veterinary Immunology and Immunopathology. 17-26.
  • 2011. Gene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition. BMC Genomics. 17 pages.
  • 2011. Analysis of polymeric immunoglobulin receptor- and CD300-like molecules from Atlantic salmon. Molecular Immunology. 462-473.
  • 2011. A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. Molecular Immunology.
  • 2010. Salmonid T cells assemble in the thymus, spleen and in novel interbranchial lymphoid tissue. Journal of Anatomy. 728-739.
  • 2009. Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes. Fish and Shellfish Immunology. 707-713.
  • 2009. CD4 homologues in Atlantic salmon. Fish and Shellfish Immunology. 10-18.
  • 2009. CD4 homologues in Atlantic salmon. Fish and Shellfish Immunology. 10-18.
  • 2008. Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. Journal of Anatomy. 202-209.
  • 2008. Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. Journal of Anatomy. 202-209.
  • 2008. Characterization of the CD3f, CD3cd and CD3e subunits of the T cell receptor complex in Atlantic salmon. Developmental and Comparative Immunology. 26-35.
  • 2008. Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon. Developmental and Comparative Immunology. 26-35.
  • 2006. Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar. Aquaculture. 453-461.
  • 2006. MHC class ll+ cells in the gills of Atlantic salmon ( Salmo salar L.) affected by amoebic gill disease. Veterinary Immunology and Immunopathology. 297-303.
  • 2006. MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease. Veterinary Immunology and Immunopathology. 297-303.
  • 2006. Identification and characterization of a second CD4-like gene in teleost fish. Molecular Immunology. 410-419.
  • 2005. Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. Journal of Fish Diseases. 13-22.
  • 2005. Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. Journal of Fish Diseases.
  • 2005. The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). Fish and Shellfish Immunology. 49-60.
  • 2005. The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). Fish and Shellfish Immunology. 49-60.
  • 2005. Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon. BMC Molecular Biology. 1-9.
  • 2005. Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M. Molecular Immunology. 345-353.
  • 2005. Characterisation of salmon and trout CD8 alpha and CD8 beta. Molecular Immunology.
  • 2005. Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish. Journal of Allergy and Clinical Immunology. 1314-1320.
  • 2004. Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon. Molecular Immunology. 553-559.
  • 2004. Granulomatous uveitis associated with vaccination in the Atlantic salmon. Veterinary pathology. 122-130.
  • 2004. Granulomatous uveitis associated with vaccination in the Atlantic salmon. Veterinary pathology. 122-130.
  • 2003. Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye. Scandinavian Journal of Immunology. 9-14.
  • 2003. Vaccination Induces Major Histocompatibility Complex Class II Expression in the Atlantic Salmon Eye. Scandinavian Journal of Immunology. 9-14.
  • 2003. Production of rabbit antisera against recombinant MHC class II beta chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). Fish and Shellfish Immunology. 115-132.
  • 2003. Production of rabbit antisera against recombinant MHC class II B chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). Fish and Shellfish Immunology. 115-132.
  • 2002. Karakterisering av immungener hos fisk. Litt historikk, status og fremtidsutsikter. Fiskehelse.
  • 2002. Identification of a novel immunoglobulin δ transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut. Molecular Immunology. 85-91.
  • 2002. Analysis of two IgM isotypes in Atlantic salmon and brown trout. Molecular Immunology. 313-321.
  • 2001. Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus. Fish and Shellfish Immunology. 257-268.
  • 2001. Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci. Developmental and Comparative Immunology. 403-417.
  • 1999. The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae. Journal of Virology. 2136-2142.
  • 1999. Molecular cloning and phylogenetic analysis of the Atlantic salmon Immunoglobulin D gene. Scandinavian Journal of Immunology. 202-210.
  • 1999. Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). Scandinavian Journal of Immunology. 619-625.
  • 1999. Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). ?. 619-625.
  • 1998. The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes. Immunological Reviews. 153-157.
  • 1998. Molecular phylogeny of mcrosoridians with particular reference to species that infect the muscles of fish. Journal of Eukaryotic Microbiology. 535-543.
  • 1997. Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar. Molecular Immunology. 631-639.
  • 1996. Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). Scandinavian Journal of Immunology. 335-344.
  • 1996. Cloning of two distinct cDNA encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). Allergy. European Journal of Allergy and Clinical Immunology. 139.
  • 1996. Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar). Immunogenetics. 9-14.
  • 1996. Avl og sykdomsresistens. Norsk Fiskeoppdrett. 25-27.
  • 1994. Immune genes of the Atlantic salmon. Application of modern genetic techniques to the study of antibodies and MHC antigens from Atlantic salmon. Aquaculture and Fisheries Management. 47-53.
  • 1994. Haploid gynogenesis. A powerful strategy for linkage analysis in fish. Animal Biotechnology.
  • 1993. Molecular cloning of major histocompability complex class I cDNAs from Atlantic salmon (Salmo salar). Immunogenetics. S. 469-473.
  • 1993. Cloning and sequence analysis of cDNAs encoding the MHC class II beta chain in Atlantic salmon (Salmo salar). Immunogenetics. 437-441.
  • 1992. The zebrafish homeobox gene Hox(zf-114): primary structure, expression pattern and evolutionary aspects. International Journal of Developmental Biology. 229-237.
  • 1992. Cloning and sequence analysis of two isotopic IgM heavy chain genes from Atlantic salmon, Salmo salar L. European Journal of Immunology. 2957-2962.
Academic lecture
  • 2019. Intramuscular vaccination of Atlantic lumpfish induces inflammation and local IgM production.
  • 2019. Distribution of different populations of T cells and B cells in the interbranchial lymphoid tissue (ILT) of salmon.
  • 2019. Characterization and development of focal red and melanised changes in the Atlantic salmon.
  • 2017. Intramuscular injection of oil-based vaccines in Atlantic lumpfish (Cyclopterus lumpus L.) – a possible route of administration or not? Emphasis on fish welfare and immune response .
  • 2017. Intramuscular injection of oil-based vaccines in Atlantic lumpfish (Cyclopterus lumpus L.) – a possible route of administration or not?
  • 2011. Tarmkreft hos laksefisk er assosiert med betennelse.
  • 2003. Analysis of IgD expression in Atlantic salmon.
  • 2002. Detection of MHC class II positive cells in the Atlantic salmon (Salmo salar).
  • 2002. Detection of MHC class II positive cells in the Atlantic salmon (Salmo salar).
  • 2001. Identification of IgD heavy chain RNA splice variants in Atlantic salmon, Salmo salar.
  • 2001. Analyse av immunoglobulin D uttrykking hos laks.
  • 2000. IgM and IgD heavy chain subvariants in Atlantic salmon and brown trout, related to ancestral tetraploidy.
  • 1993. Two isotypic IgM heavy chain genes of the Atlantic salmon.
  • 1993. MHC polymorphism in Atlantic salmon.
Reader opinion piece
  • 2011. Ville reinsdyr trives best. Bergens Tidende. 28-28.
Thesis at a second degree level
  • 2007. Deteksjon av IgM-positive celler i blodutstryk fra kveite (Hippoglossus hippoglossus L.): in situ hybridisering med to typer prober.
  • 2004. Expression of two fragments from the atlantic salmon major histocompability class 1α chain in E.coli, utilizing two different.
  • 2004. Analyse av IgM- og IgD-genuttrykking i ulike vev hos atlantisk laks (Salmo salar L.).
Popular scientific article
  • 2014. Laksen har dobbelt sett med gener (INNSIKT-artikkel). Bergens Tidende. 14-15.
  • 1999. En nyoppdaget type antistoffer hos beinfisk. Fiskehelse. 17-21.
Feature article
  • 1997. cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). Allergy. European Journal of Allergy and Clinical Immunology. 49.
  • 1997. cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). Allergy. European Journal of Allergy and Clinical Immunology. 49.
Doctoral dissertation
  • 2019. Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta).
  • 1993. Immune genes of the Atlantic salmon. Cloning and sequence analyses of genes encoding the IgM heavy chain, the MHC class I alpha-chain and the MHC class II beta-chain.
Academic chapter/article/Conference paper
  • 2007. The fish immune system. 12 pages.
  • 2006. Immunsystemet hos fisk. 12 pages.
Abstract
  • 2013. The immunological function of the interbranchial lymphoid tissue (ILT). Fish and Shellfish Immunology. 1636-1636.
  • 2013. Expression of immune related genes in the Atlantic salmon intestine. Fish and Shellfish Immunology. 1662-1662.
  • 2013. Characterization of serum IgM in teleost fish, with emphasis on salmonids. Fish and Shellfish Immunology. 1656-1656.
  • 2013. Anatomy of the interbranchial lymphoid tissue (ILT) in salmonid fish. Fish and Shellfish Immunology. 1651-1651.
Poster
  • 2019. Intramuscular injection of an oil-based vaccine in Atlantic lumpfish induces local IgM production.
  • 2019. Inflammatory changes and melanization in the Atlantic salmon (Salmo salar) targeted by in situ hybridization.
  • 2011. Intestinal epithelial dysplasia and adenocarcinoma in salmonids is associated with inflammation.
  • 2011. Comparative pathology of cardiac diseases in Atlantic salmon (Salmo salar L.) by immunohistochemistry.
  • 2010. Comparative pathology of cardiac diseases in Atlantic salmon (Salmo salar L.) by immunohistochemistry.
  • 2003. Major histocompatibility complex (MHC) class II expression during soybean meal-induced enteritis in Atlantic salmon (Salmo salar L.).
  • 2003. Major histocompatibility complex (MHC) class II expression during soybean meal-induced enteritis in Atlantic salmon (Salmo salar L.).
  • 2002. The immunoglobulin heavy chain gene loci in Atlantic salmon: Analysis of IgM subvariants related to ancestral tetraploidy and identification of a novel IgD transcript.
  • 2002. Analyse av immunoglobulin D uttrykking hos laks.
Article in business/trade/industry journal
  • 2013. VACCINATION of Atlantic salmon leads to long-lasting higher levels of serum immunoglobulin and possible skewed ratios of two distinct IgM isotypes. Advances in Bioscience and Biotechnology. 85-90.

More information in national current research information system (CRIStin)

Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes
Author(s): Overgard, AC; Hordvik, I; Nerland, AH, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 27   Issue: 6   Pages: 707-713   Published: 2009

 

CD4 homologues in Atlantic salmon
Author(s): Moore, LJ; Dijkstra, JM; Koppang, EO, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 26   Issue: 1   Pages: 10-18   Published: 2009

 

Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon
Author(s): Haugarvoll, E; Bjerkas, I; Nowak, BF, et al.
Source: JOURNAL OF ANATOMY   Volume: 213   Issue: 2   Pages: 202-209   Published: 2008

 

Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon
Author(s): Liu, Y; Moore, L; Koppang, EO, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY   Volume: 32   Issue: 1   Pages: 26-35   Published: 2008

 

FABP3 and FABP10 in Atlantic salmon (Salmo salar L.) - General effects of dietary fatty acid composition and life cycle variations
Author(s): Jordal, AEO; Hordvik, I; Pelsers, M, et al.
Source: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   Volume: 145   Issue: 2   Pages: 147-158   Published: OCT 2006

 

Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar
Author(s): Hevroy, EM; Jordal, AEO; Hordvik, I, et al.
Source: AQUACULTURE   Volume: 252   Issue: 2-4   Pages: 453-461   Published: MAR 10 2006

 

Identification and characterization of a second CD4-like gene in teleost fish
Author(s): Dijkstra, JM; Somamoto, T; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 43   Issue: 5   Pages: 410-419   Published: FEB 2006

 

MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease
Author(s): Morrison, RN; Koppang, EO; Hordvik, I, et al.
Source: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY   Volume: 109   Issue: 3-4   Pages: 297-303   Published: FEB 15 2006

 

Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish
Author(s): Van Do, T; Elsayed, S; Florvaag, E, et al.
Source: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Volume: 116   Issue: 6   Pages: 1314-1320   Published: DEC 2005

 

Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon
Author(s): Olsvik, PA; Lie, KK; Jordal, AEO, et al.
Source: BMC MOLECULAR BIOLOGY   Volume: 6   Article Number: 21   Published: NOV 17 2005

 

Characterisation of salmon and trout CD8 alpha and CD8 beta
Author(s): Moore, LJ; Somamoto, T; Lie, KK, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 42   Issue: 10   Pages: 1225-1234   Published: JUN 2005

 

Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 42   Issue: 3   Pages: 345-353   Published: FEB 2005

 

The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss)
Author(s): Fischer, U; Dijkstra, JM; Kollner, B, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 18   Issue: 1   Pages: 49-60   Published: JAN 2005

 

Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: JOURNAL OF FISH DISEASES   Volume: 28   Issue: 1   Pages: 13-22   Published: JAN 2005

 

Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon
Author(s): Hordvik, I; Torvund, J; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 41   Issue: 5   Pages: 553-559   Published: JUL 2004

 

Granulomatous uveitis associated with vaccination in the Atlantic salmon
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: VETERINARY PATHOLOGY   Volume: 41   Issue: 2   Pages: 122-130   Published: MAR 2004

 

Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye
Author(s): Koppang, EO; Bjerkas, E; Bjerkas, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 58   Issue: 1   Pages: 9-14   Published: JUL 2003

 

The major allergen (parvalbumin) of codfish is encoded by at least two isotypic genes: cDNA cloning, expression and antibody binding of the recombinant allergens
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 10   Pages: 595-602   Published: JAN 2003

 

Analysis of two IgM isotypes in Atlantic salmon and brown trout
Author(s): Hordvik, I; Berven, FS; Solem, ST, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 5-6   Pages: 313-321   Published: OCT 2002

 

Identification of a novel immunoglobulin delta transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut
Author(s): Hordvik, I
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 1-2   Pages: 85-91   Published: SEP 2002

 

Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci.
Author(s): Solem, ST; Hordvik, I; Killie, JEA, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY   Volume: 25   Issue: 5-6   Pages: 403-417   Published: JUN-JUL 2001

 

Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus
Author(s): Hatten, F; Fredriksen, A; Hordvik, I, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 11   Issue: 3   Pages: 257-268   Published: APR 2001

 

Expression and analysis of recombinant salmon parvalbumin, the major allergen in atlantic salmon (Salmo salar)
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 50   Issue: 6   Pages: 619-625   Published: 1999

 

Molecular cloning and phylogenetic analysis of the Atlantic salmon immunoglobulin D gene
Author(s): Hordvik, I; Thevarajan, J; Samdal, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 50   Issue: 2   Pages: 202-210   Published: AUG 1999

 

The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae
Author(s): Krossoy, B; Hordvik, I; Nilsen, F, et al.
Source: JOURNAL OF VIROLOGY   Volume: 73   Issue: 3   Pages: 2136-2142   Published: MAR 1999

 

The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes
Author(s): Hordvik, I
Source: IMMUNOLOGICAL REVIEWS   Volume: 166   Pages: 153-157   Published: DEC 1998

 

Molecular phylogeny of microsporidians with particular reference to species that infect the muscles of fish
Author(s): Nilsen, F; Endresen, C; Hordvik, I
Source: JOURNAL OF EUKARYOTIC MICROBIOLOGY   Volume: 45   Issue: 5   Pages: 535-543   Published: SEP-OCT 1998

 

Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar
Author(s): Hordvik, I; Lindstrom, CD; Voie, AM, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 34   Issue: 8-9   Pages: 631-639   Published: JUN 1997

 

Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar)
Author(s): Hordvik, I; Jacob, ALJ; Charlemagne, J, et al.
Source: IMMUNOGENETICS   Volume: 45   Issue: 1   Pages: 9-14   Published: 1996

 

Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar)
Author(s): Lindstrom, CDV; VanDo, T; Hordvik, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 44   Issue: 4   Pages: 335-344   Published: OCT 1996

 

Immune genes of the Atlantic salmon, Salmo salar L.: Application of modern molecular genetic techniques to the study of antibodies and major histocompatibility complex antigens
Author(s): Hordvik, I.
Source: Aquaculture and Fisheries Management   Volume: 25   Issue: 1   Pages: 47-53   Published: 1994

 

Haploid gynogenesis: A powerful strategy for linkage analysis in fish
Author(s): Lie, O.; Slettan, A.; Lingaas, F., et al.
Source: Animal Biotechnology   Volume: 5   Issue: 1   Pages: 33-45   Published: 1994

 

MOLECULAR-CLONING OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I CDNAS FROM ATLANTIC SALMON (SALMO-SALAR)
Author(s): GRIMHOLT, U; HORDVIK, I; FOSSE, VM, et al.
Source: IMMUNOGENETICS   Volume: 37   Issue: 6   Pages: 469-473   Published: FEB 1993

 

CLONING AND SEQUENCE-ANALYSIS OF CDNAS ENCODING THE MHC CLASS-II BETA-CHAIN IN ATLANTIC SALMON (SALMO-SALAR)
Author(s): HORDVIK, I; GRIMHOLT, U; FOSSE, VM, et al.
Source: IMMUNOGENETICS   Volume: 37   Issue: 6   Pages: 437-441   Published: FEB 1993

 

CLONING AND SEQUENCE-ANALYSIS OF 2 ISOTYPIC IGM HEAVY-CHAIN GENES FROM ATLANTIC SALMON, SALMO-SALAR L
Author(s): HORDVIK, I; VOIE, AM; GLETTE, J, et al.
Source: EUROPEAN JOURNAL OF IMMUNOLOGY   Volume: 22   Issue: 11   Pages: 2957-2962   Published: NOV 1992